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Showing metabocard for Oleic acid (HMDB0000207)

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enzymes (11) Show 11 proteins
Record Information
Version5.0
StatusDetected and Quantified
Creation Date2005-11-16 15:48:42 UTC
Update Date2022-03-07 02:48:59 UTC
HMDB IDHMDB0000207
Secondary Accession Numbers
  • HMDB0002066
  • HMDB00207
  • HMDB02066
Metabolite Identification
Common NameOleic acid
DescriptionOleic acid (or 9Z)-Octadecenoic acid) is an unsaturated C-18 or an omega-9 fatty acid that is the most widely distributed and abundant fatty acid in nature. It occurs naturally in various animal and vegetable fats and oils. It is an odorless, colorless oil, although commercial samples may be yellowish. The name derives from the Latin word oleum, which means oil. Oleic acid is the most abundant fatty acid in human adipose tissue, and the second most abundant in human tissues overall, following palmitic acid. Oleic acid is a component of the normal human diet, being a part of animal fats and vegetable oils. Triglycerides of oleic acid represent the majority of olive oil (about 70%). Oleic acid triglycerides also make up 59-75% of pecan oil, 61% of canola oil, 36-67% of peanut oil, 60% of macadamia oil, 20-80% of sunflower oil, 15-20% of grape seed oil, sea buckthorn oil, 40% of sesame oil, and 14% of poppyseed oil. High oleic variants of plant sources such as sunflower (~80%) and canola oil (70%) also have been developed. consumption has been associated with decreased low-density lipoprotein (LDL) cholesterol, and possibly with increased high-density lipoprotein (HDL) cholesterol, however, the ability of oleic acid to raise HDL is still debated. Oleic acid may be responsible for the hypotensive (blood pressure reducing) effects of olive oil that is considered a health benefit. Oleic acid is used in manufacturing of surfactants, soaps, plasticizers. It is also used as an emulsifying agent in foods and pharmaceuticals. Oleic acid is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent.
Structure
Data?1600188291
MOL3D MOLSDF3D SDFPDB3D PDBSMILESInChI

MOL for HMDB0000207 (Oleic acid)


  Mrv1652309272007412D          

 20 19  0  0  0  0            999 V2000
   -3.7393   -0.6182    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4544   -0.2068    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1677   -0.6182    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8826   -0.2068    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.5958   -0.6182    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8826    0.6182    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0254   -0.2046    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3102   -0.6160    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5965   -0.2023    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6574   -0.2013    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1669   -0.2013    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8821   -0.6127    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8010   -0.6127    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0859   -0.2013    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3726   -0.6127    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5149   -0.1991    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2300   -0.6104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9438   -0.1968    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6582   -0.6072    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3718   -0.1932    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  4  6  2  0  0  0  0
  1  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
 10 11  2  0  0  0  0
 11 12  1  0  0  0  0
  9 12  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 13 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 10 15  1  0  0  0  0
 19 20  1  0  0  0  0
M  END
Download

3D MOL for HMDB0000207 (Oleic acid)

HMDB0000207
     RDKit          3D
Oleic acid
 54 53  0  0  0  0  0  0  0  0999 V2000
   -6.3665    1.9995    0.8770 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4256    0.5166    1.1015 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7428   -0.2404   -0.0352 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2925    0.2245   -0.0651 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5347   -0.4807   -1.1718 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5095   -1.9541   -1.0277 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9184   -2.5399    0.1807 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4833   -2.3002    0.4822 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0537   -0.9265    0.6722 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1487   -0.2966   -0.0272 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6247   -0.8351   -1.1502 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1189   -0.8113   -0.8620 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5929    0.6048   -0.6117 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1014    0.4962   -0.3356 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6066    1.8748   -0.0836 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0845    1.8301    0.1871 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3987    0.9893    1.3900 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8894    1.0142    1.5785 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.6454    1.6466    0.8216 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.4842    0.3132    2.6314 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1086    2.2561   -0.1694 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6034    2.4667    1.5225 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.3511    2.4509    1.1646 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9304    0.3029    2.0623 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.4836    0.1963    1.2122 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1888    0.0294   -1.0142 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8512   -1.3023    0.1869 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3141    1.3011   -0.3403 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8113    0.1431    0.9143 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1542   -0.2718   -2.1099 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6016    0.0362   -1.3453 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0858   -2.3672   -1.9771 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5904   -2.3038   -1.0644 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0571   -3.6646    0.0989 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5491   -2.2706    1.0622 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2619   -2.9301    1.4288 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8254   -2.8055   -0.2583 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5466   -0.3679    1.4935 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0483    0.7450    0.2617 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2642   -1.8180   -1.4471 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.4390   -0.1696   -2.0585 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.6189   -1.2104   -1.7679 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.3314   -1.3861    0.0511 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.4425    1.2579   -1.4886 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0647    1.0523    0.2506 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.5262    0.0221   -1.2385 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2410   -0.2171    0.4936 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0974    2.3092    0.7951 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.4173    2.4692   -1.0089 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6155    1.3969   -0.6892 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.4157    2.8755    0.3577 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.9504    1.3885    2.3123 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.0949   -0.0543    1.2628 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.6763   -0.6849    2.5088 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  2  0
 10 11  1  0
 11 12  1  0
 12 13  1  0
 13 14  1  0
 14 15  1  0
 15 16  1  0
 16 17  1  0
 17 18  1  0
 18 19  2  0
 18 20  1  0
  1 21  1  0
  1 22  1  0
  1 23  1  0
  2 24  1  0
  2 25  1  0
  3 26  1  0
  3 27  1  0
  4 28  1  0
  4 29  1  0
  5 30  1  0
  5 31  1  0
  6 32  1  0
  6 33  1  0
  7 34  1  0
  7 35  1  0
  8 36  1  0
  8 37  1  0
  9 38  1  0
 10 39  1  0
 11 40  1  0
 11 41  1  0
 12 42  1  0
 12 43  1  0
 13 44  1  0
 13 45  1  0
 14 46  1  0
 14 47  1  0
 15 48  1  0
 15 49  1  0
 16 50  1  0
 16 51  1  0
 17 52  1  0
 17 53  1  0
 20 54  1  0
M  END
Download

3D SDF for HMDB0000207 (Oleic acid)


  Mrv1652309272007412D          

 20 19  0  0  0  0            999 V2000
   -3.7393   -0.6182    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4544   -0.2068    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1677   -0.6182    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8826   -0.2068    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.5958   -0.6182    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8826    0.6182    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0254   -0.2046    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3102   -0.6160    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5965   -0.2023    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6574   -0.2013    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1669   -0.2013    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8821   -0.6127    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8010   -0.6127    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0859   -0.2013    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3726   -0.6127    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5149   -0.1991    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2300   -0.6104    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9438   -0.1968    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6582   -0.6072    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3718   -0.1932    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  4  6  2  0  0  0  0
  1  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
 10 11  2  0  0  0  0
 11 12  1  0  0  0  0
  9 12  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 13 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 10 15  1  0  0  0  0
 19 20  1  0  0  0  0
M  END
> <DATABASE_ID>
HMDB0000207

> <DATABASE_NAME>
hmdb

> <SMILES>
CCCCCCCC\C=C/CCCCCCCC(O)=O

> <INCHI_IDENTIFIER>
InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-

> <INCHI_KEY>
ZQPPMHVWECSIRJ-KTKRTIGZSA-N

> <FORMULA>
C18H34O2

> <MOLECULAR_WEIGHT>
282.4614

> <EXACT_MASS>
282.255880332

> <JCHEM_ACCEPTOR_COUNT>
2

> <JCHEM_ATOM_COUNT>
54

> <JCHEM_AVERAGE_POLARIZABILITY>
37.092366766057495

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(9Z)-octadec-9-enoic acid

> <ALOGPS_LOGP>
7.68

> <JCHEM_LOGP>
6.783798451000001

> <ALOGPS_LOGS>
-6.37

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
0

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-1

> <JCHEM_PKA_STRONGEST_ACIDIC>
4.988167283903808

> <JCHEM_POLAR_SURFACE_AREA>
37.3

> <JCHEM_REFRACTIVITY>
87.4022

> <JCHEM_ROTATABLE_BOND_COUNT>
15

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
1.21e-04 g/l

> <JCHEM_TRADITIONAL_IUPAC>
oleic acid

> <JCHEM_VEBER_RULE>
0

$$$$
Download

3D-SDF for HMDB0000207 (Oleic acid)

HMDB0000207
     RDKit          3D
Oleic acid
 54 53  0  0  0  0  0  0  0  0999 V2000
   -6.3665    1.9995    0.8770 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4256    0.5166    1.1015 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7428   -0.2404   -0.0352 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2925    0.2245   -0.0651 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5347   -0.4807   -1.1718 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5095   -1.9541   -1.0277 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9184   -2.5399    0.1807 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4833   -2.3002    0.4822 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0537   -0.9265    0.6722 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1487   -0.2966   -0.0272 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6247   -0.8351   -1.1502 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1189   -0.8113   -0.8620 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5929    0.6048   -0.6117 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1014    0.4962   -0.3356 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.6066    1.8748   -0.0836 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.0845    1.8301    0.1871 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3987    0.9893    1.3900 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8894    1.0142    1.5785 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.6454    1.6466    0.8216 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.4842    0.3132    2.6314 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1086    2.2561   -0.1694 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6034    2.4667    1.5225 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.3511    2.4509    1.1646 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.9304    0.3029    2.0623 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.4836    0.1963    1.2122 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1888    0.0294   -1.0142 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.8512   -1.3023    0.1869 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3141    1.3011   -0.3403 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8113    0.1431    0.9143 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1542   -0.2718   -2.1099 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6016    0.0362   -1.3453 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0858   -2.3672   -1.9771 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5904   -2.3038   -1.0644 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0571   -3.6646    0.0989 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5491   -2.2706    1.0622 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2619   -2.9301    1.4288 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8254   -2.8055   -0.2583 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5466   -0.3679    1.4935 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0483    0.7450    0.2617 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.2642   -1.8180   -1.4471 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.4390   -0.1696   -2.0585 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.6189   -1.2104   -1.7679 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.3314   -1.3861    0.0511 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.4425    1.2579   -1.4886 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0647    1.0523    0.2506 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.5262    0.0221   -1.2385 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.2410   -0.2171    0.4936 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0974    2.3092    0.7951 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.4173    2.4692   -1.0089 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.6155    1.3969   -0.6892 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.4157    2.8755    0.3577 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.9504    1.3885    2.3123 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.0949   -0.0543    1.2628 H   0  0  0  0  0  0  0  0  0  0  0  0
    8.6763   -0.6849    2.5088 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  2  0
 10 11  1  0
 11 12  1  0
 12 13  1  0
 13 14  1  0
 14 15  1  0
 15 16  1  0
 16 17  1  0
 17 18  1  0
 18 19  2  0
 18 20  1  0
  1 21  1  0
  1 22  1  0
  1 23  1  0
  2 24  1  0
  2 25  1  0
  3 26  1  0
  3 27  1  0
  4 28  1  0
  4 29  1  0
  5 30  1  0
  5 31  1  0
  6 32  1  0
  6 33  1  0
  7 34  1  0
  7 35  1  0
  8 36  1  0
  8 37  1  0
  9 38  1  0
 10 39  1  0
 11 40  1  0
 11 41  1  0
 12 42  1  0
 12 43  1  0
 13 44  1  0
 13 45  1  0
 14 46  1  0
 14 47  1  0
 15 48  1  0
 15 49  1  0
 16 50  1  0
 16 51  1  0
 17 52  1  0
 17 53  1  0
 20 54  1  0
M  END
Download

PDB for HMDB0000207 (Oleic acid)

HEADER    PROTEIN                                 27-SEP-20   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   27-SEP-20         0                                  
HETATM    1  C   UNK     0      -6.980  -1.154   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -8.315  -0.386   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -9.646  -1.154   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0     -10.981  -0.386   0.000  0.00  0.00           C+0
HETATM    5  O   UNK     0     -12.312  -1.154   0.000  0.00  0.00           O+0
HETATM    6  O   UNK     0     -10.981   1.154   0.000  0.00  0.00           O+0
HETATM    7  C   UNK     0      -5.647  -0.382   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      -4.312  -1.150   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      -2.980  -0.378   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       1.227  -0.376   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      -0.312  -0.376   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0      -1.647  -1.144   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       5.229  -1.144   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       3.894  -0.376   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       2.562  -1.144   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0       6.561  -0.372   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       7.896  -1.139   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       9.228  -0.367   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      10.562  -1.133   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      11.894  -0.361   0.000  0.00  0.00           C+0
CONECT    1    2    7                                                       
CONECT    2    1    3                                                       
CONECT    3    2    4                                                       
CONECT    4    3    5    6                                                  
CONECT    5    4                                                            
CONECT    6    4                                                            
CONECT    7    1    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   12                                                       
CONECT   10   11   15                                                       
CONECT   11   10   12                                                       
CONECT   12   11    9                                                       
CONECT   13   14   16                                                       
CONECT   14   13   15                                                       
CONECT   15   14   10                                                       
CONECT   16   13   17                                                       
CONECT   17   16   18                                                       
CONECT   18   17   19                                                       
CONECT   19   18   20                                                       
CONECT   20   19                                                            
MASTER        0    0    0    0    0    0    0    0   20    0   38    0
END
Download

3D PDB for HMDB0000207 (Oleic acid)

COMPND    HMDB0000207
HETATM    1  C1  UNL     1      -6.367   1.999   0.877  1.00  0.00           C  
HETATM    2  C2  UNL     1      -6.426   0.517   1.102  1.00  0.00           C  
HETATM    3  C3  UNL     1      -5.743  -0.240  -0.035  1.00  0.00           C  
HETATM    4  C4  UNL     1      -4.292   0.225  -0.065  1.00  0.00           C  
HETATM    5  C5  UNL     1      -3.535  -0.481  -1.172  1.00  0.00           C  
HETATM    6  C6  UNL     1      -3.510  -1.954  -1.028  1.00  0.00           C  
HETATM    7  C7  UNL     1      -2.918  -2.540   0.181  1.00  0.00           C  
HETATM    8  C8  UNL     1      -1.483  -2.300   0.482  1.00  0.00           C  
HETATM    9  C9  UNL     1      -1.054  -0.926   0.672  1.00  0.00           C  
HETATM   10  C10 UNL     1      -0.149  -0.297  -0.027  1.00  0.00           C  
HETATM   11  C11 UNL     1       0.625  -0.835  -1.150  1.00  0.00           C  
HETATM   12  C12 UNL     1       2.119  -0.811  -0.862  1.00  0.00           C  
HETATM   13  C13 UNL     1       2.593   0.605  -0.612  1.00  0.00           C  
HETATM   14  C14 UNL     1       4.101   0.496  -0.336  1.00  0.00           C  
HETATM   15  C15 UNL     1       4.607   1.875  -0.084  1.00  0.00           C  
HETATM   16  C16 UNL     1       6.085   1.830   0.187  1.00  0.00           C  
HETATM   17  C17 UNL     1       6.399   0.989   1.390  1.00  0.00           C  
HETATM   18  C18 UNL     1       7.889   1.014   1.579  1.00  0.00           C  
HETATM   19  O1  UNL     1       8.645   1.647   0.822  1.00  0.00           O  
HETATM   20  O2  UNL     1       8.484   0.313   2.631  1.00  0.00           O  
HETATM   21  H1  UNL     1      -6.109   2.256  -0.169  1.00  0.00           H  
HETATM   22  H2  UNL     1      -5.603   2.467   1.522  1.00  0.00           H  
HETATM   23  H3  UNL     1      -7.351   2.451   1.165  1.00  0.00           H  
HETATM   24  H4  UNL     1      -5.930   0.303   2.062  1.00  0.00           H  
HETATM   25  H5  UNL     1      -7.484   0.196   1.212  1.00  0.00           H  
HETATM   26  H6  UNL     1      -6.189   0.029  -1.014  1.00  0.00           H  
HETATM   27  H7  UNL     1      -5.851  -1.302   0.187  1.00  0.00           H  
HETATM   28  H8  UNL     1      -4.314   1.301  -0.340  1.00  0.00           H  
HETATM   29  H9  UNL     1      -3.811   0.143   0.914  1.00  0.00           H  
HETATM   30  H10 UNL     1      -4.154  -0.272  -2.110  1.00  0.00           H  
HETATM   31  H11 UNL     1      -2.602   0.036  -1.345  1.00  0.00           H  
HETATM   32  H12 UNL     1      -3.086  -2.367  -1.977  1.00  0.00           H  
HETATM   33  H13 UNL     1      -4.590  -2.304  -1.064  1.00  0.00           H  
HETATM   34  H14 UNL     1      -3.057  -3.665   0.099  1.00  0.00           H  
HETATM   35  H15 UNL     1      -3.549  -2.271   1.062  1.00  0.00           H  
HETATM   36  H16 UNL     1      -1.262  -2.930   1.429  1.00  0.00           H  
HETATM   37  H17 UNL     1      -0.825  -2.806  -0.258  1.00  0.00           H  
HETATM   38  H18 UNL     1      -1.547  -0.368   1.493  1.00  0.00           H  
HETATM   39  H19 UNL     1       0.048   0.745   0.262  1.00  0.00           H  
HETATM   40  H20 UNL     1       0.264  -1.818  -1.447  1.00  0.00           H  
HETATM   41  H21 UNL     1       0.439  -0.170  -2.058  1.00  0.00           H  
HETATM   42  H22 UNL     1       2.619  -1.210  -1.768  1.00  0.00           H  
HETATM   43  H23 UNL     1       2.331  -1.386   0.051  1.00  0.00           H  
HETATM   44  H24 UNL     1       2.442   1.258  -1.489  1.00  0.00           H  
HETATM   45  H25 UNL     1       2.065   1.052   0.251  1.00  0.00           H  
HETATM   46  H26 UNL     1       4.526   0.022  -1.239  1.00  0.00           H  
HETATM   47  H27 UNL     1       4.241  -0.217   0.494  1.00  0.00           H  
HETATM   48  H28 UNL     1       4.097   2.309   0.795  1.00  0.00           H  
HETATM   49  H29 UNL     1       4.417   2.469  -1.009  1.00  0.00           H  
HETATM   50  H30 UNL     1       6.615   1.397  -0.689  1.00  0.00           H  
HETATM   51  H31 UNL     1       6.416   2.876   0.358  1.00  0.00           H  
HETATM   52  H32 UNL     1       5.950   1.388   2.312  1.00  0.00           H  
HETATM   53  H33 UNL     1       6.095  -0.054   1.263  1.00  0.00           H  
HETATM   54  H34 UNL     1       8.676  -0.685   2.509  1.00  0.00           H  
CONECT    1    2   21   22   23
CONECT    2    3   24   25
CONECT    3    4   26   27
CONECT    4    5   28   29
CONECT    5    6   30   31
CONECT    6    7   32   33
CONECT    7    8   34   35
CONECT    8    9   36   37
CONECT    9   10   10   38
CONECT   10   11   39
CONECT   11   12   40   41
CONECT   12   13   42   43
CONECT   13   14   44   45
CONECT   14   15   46   47
CONECT   15   16   48   49
CONECT   16   17   50   51
CONECT   17   18   52   53
CONECT   18   19   19   20
CONECT   20   54
END
Download

SMILES for HMDB0000207 (Oleic acid)

CCCCCCCC\C=C/CCCCCCCC(O)=O
Download

INCHI for HMDB0000207 (Oleic acid)

InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
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View in JSmolView Stereo Labels
Synonyms
ValueSource
(9Z)-Octadecenoic acidChEBI
(Z)-Octadec-9-enoic acidChEBI
18:1 N-9ChEBI
18:1DElta9cisChEBI
C18:1 N-9ChEBI
cis-9-Octadecenoic acidChEBI
cis-Delta(9)-Octadecenoic acidChEBI
cis-Oleic acidChEBI
FA 18:1ChEBI
Octadec-9-enoic acidChEBI
OelsaeureChEBI
OleateChEBI
(9Z)-OctadecenoateGenerator
(Z)-Octadec-9-enoateGenerator
cis-9-OctadecenoateGenerator
cis-delta(9)-OctadecenoateGenerator
cis-Δ(9)-octadecenoateGenerator
cis-Δ(9)-octadecenoic acidGenerator
cis-OleateGenerator
Octadec-9-enoateGenerator
(9Z)-9-OctadecenoateHMDB
(9Z)-9-Octadecenoic acidHMDB
(Z)-9-OctadecanoateHMDB
(Z)-9-Octadecanoic acidHMDB
9,10-OctadecenoateHMDB
9,10-Octadecenoic acidHMDB
9-(Z)-OctadecenoateHMDB
9-(Z)-Octadecenoic acidHMDB
9-OctadecenoateHMDB
9-Octadecenoic acidHMDB
Century CD fatty acidHMDB
cis-Octadec-9-enoateHMDB
cis-Octadec-9-enoic acidHMDB
DistolineHMDB
Emersol 210HMDB
Emersol 211HMDB
Emersol 213HMDB
Emersol 220 white oleateHMDB
Emersol 220 white oleic acidHMDB
Emersol 221 low titer white oleateHMDB
Emersol 221 low titer white oleic acidHMDB
Emersol 233LLHMDB
Emersol 6321HMDB
Emersol 6333 NFHMDB
Emersol 7021HMDB
Glycon roHMDB
Glycon woHMDB
Groco 2HMDB
Groco 4HMDB
Groco 5lHMDB
Groco 6HMDB
Industrene 104HMDB
Industrene 105HMDB
Industrene 205HMDB
Industrene 206HMDB
L'acide oleiqueHMDB
MetauponHMDB
OelsauereHMDB
Oleic acid extra pureHMDB
OleinateHMDB
Oleinic acidHMDB
PamolynHMDB
Pamolyn 100HMDB
Pamolyn 100 FGHMDB
Pamolyn 100 FGKHMDB
Pamolyn 125HMDB
Priolene 6900HMDB
Red oilHMDB
Tego-oleic 130HMDB
Vopcolene 27HMDB
Wecoline ooHMDB
Z-9-OctadecenoateHMDB
Z-9-Octadecenoic acidHMDB
Acid, 9-octadecenoicHMDB
Acid, oleicHMDB
9 Octadecenoic acidHMDB
Acid, cis-9-octadecenoicHMDB
cis 9 Octadecenoic acidHMDB
FA(18:1(9Z))HMDB
FA(18:1n9)HMDB
Chemical FormulaC18H34O2
Average Molecular Weight282.4614
Monoisotopic Molecular Weight282.255880332
IUPAC Name(9Z)-octadec-9-enoic acid
Traditional Nameoleic acid
CAS Registry Number112-80-1
SMILES
CCCCCCCC\C=C/CCCCCCCC(O)=O
InChI Identifier
InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
InChI KeyZQPPMHVWECSIRJ-KTKRTIGZSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as long-chain fatty acids. These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassFatty Acyls
Sub ClassFatty acids and conjugates
Direct ParentLong-chain fatty acids
Alternative Parents
Substituents
  • Long-chain fatty acid
  • Unsaturated fatty acid
  • Straight chain fatty acid
  • Monocarboxylic acid or derivatives
  • Carboxylic acid
  • Carboxylic acid derivative
  • Organic oxygen compound
  • Organic oxide
  • Hydrocarbon derivative
  • Organooxygen compound
  • Carbonyl group
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Ontology
Physiological effect
Organoleptic effect
Disposition
Biological locationSource
Process
Naturally occurring process
Role
Biological roleIndustrial application
Physical Properties
StateLiquid
Experimental Molecular Properties
PropertyValueReference
Melting Point13.4 °CNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Experimental Chromatographic Properties

Experimental Collision Cross Sections

Adduct TypeData SourceCCS Value (Å2)Reference
[M-H]-MetCCS_train_neg173.87530932474
[M-H]-Not Available175.2http://allccs.zhulab.cn/database/detail?ID=AllCCS00000183
Predicted Molecular Properties
PropertyValueSource
Water Solubility0.00012 g/LALOGPS
logP7.68ALOGPS
logP6.78ChemAxon
logS-6.4ALOGPS
pKa (Strongest Acidic)4.99ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area37.3 ŲChemAxon
Rotatable Bond Count15ChemAxon
Refractivity87.4 m³·mol⁻¹ChemAxon
Polarizability37.09 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityNoChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted Chromatographic Properties

Predicted Collision Cross Sections

PredictorAdduct TypeCCS Value (Å2)Reference
DarkChem[M+H]+176.56531661259
DarkChem[M-H]-177.26531661259
AllCCS[M+H]+179.56932859911
AllCCS[M-H]-179.42832859911
DeepCCS[M+H]+180.77130932474
DeepCCS[M-H]-176.75230932474
DeepCCS[M-2H]-213.90330932474
DeepCCS[M+Na]+189.82830932474
AllCCS[M+H]+179.632859911
AllCCS[M+H-H2O]+176.632859911
AllCCS[M+NH4]+182.332859911
AllCCS[M+Na]+183.132859911
AllCCS[M-H]-179.432859911
AllCCS[M+Na-2H]-181.032859911
AllCCS[M+HCOO]-182.932859911

Predicted Kovats Retention Indices

Underivatized

MetaboliteSMILESKovats RI ValueColumn TypeReference
Oleic acidCCCCCCCC\C=C/CCCCCCCC(O)=O3141.2Standard polar33892256
Oleic acidCCCCCCCC\C=C/CCCCCCCC(O)=O2093.8Standard non polar33892256
Oleic acidCCCCCCCC\C=C/CCCCCCCC(O)=O2150.1Semi standard non polar33892256

Derivatized

Derivative Name / StructureSMILESKovats RI ValueColumn TypeReference
Oleic acid,1TMS,isomer #1CCCCCCCC/C=C\CCCCCCCC(=O)O[Si](C)(C)C2217.5Semi standard non polar33892256
Oleic acid,1TBDMS,isomer #1CCCCCCCC/C=C\CCCCCCCC(=O)O[Si](C)(C)C(C)(C)C2477.4Semi standard non polar33892256
Spectra

GC-MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Experimental GC-MSGC-MS Spectrum - Oleic acid GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (1 TMS)splash10-00vi-9500000000-cdb5366d3ece43c3e1662014-06-16HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Oleic acid GC-MS (1 TMS)splash10-00nb-5900000000-fc03835c9c8fddb279702014-06-16HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Oleic acid EI-B (Non-derivatized)splash10-052f-9100000000-7618883a87bd14687fd52017-09-12HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Oleic acid GC-EI-TOF (Non-derivatized)splash10-00vi-9500000000-cdb5366d3ece43c3e1662017-09-12HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Oleic acid GC-MS (Non-derivatized)splash10-00nb-5900000000-fc03835c9c8fddb279702017-09-12HMDB team, MONA, MassBankView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Oleic acid GC-MS (Non-derivatized) - 70eV, Positivesplash10-0f6x-9640000000-29b5681d79890854ef2b2016-09-22Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Oleic acid GC-MS (1 TMS) - 70eV, Positivesplash10-0fe0-9431000000-1879934642ac672cb4012017-10-06Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Oleic acid GC-MS (Non-derivatized) - 70eV, PositiveNot Available2021-10-12Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Oleic acid GC-MS (TBDMS_1_1) - 70eV, PositiveNot Available2021-11-05Wishart LabView Spectrum
MSMass Spectrum (Electron Ionization)splash10-052f-9100000000-350dc6d7ac541a3c5b672018-05-25Not AvailableView Spectrum

MS/MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid Quattro_QQQ 10V, N/A-QTOF (Annotated)splash10-00l2-4790000000-aefa66e9f83fcb24ead62012-07-24HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid Quattro_QQQ 25V, N/A-QTOF (Annotated)splash10-0apm-9100000000-a71c58b95cb65487eeed2012-07-24HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid Quattro_QQQ 40V, N/A-QTOF (Annotated)splash10-0aou-9000000000-5889cbe3dd606123df502012-07-24HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid FAB-EBEB (JMS-HX/HX 110A, JEOL) , Negative-QTOFsplash10-001i-0090000000-89531b488fbe899c09e62012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid ESI-TOF 10V, Negative-QTOFsplash10-004i-0092000000-b8aabbdc61f9b89ac3592017-08-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid ESI-TOF 20V, Negative-QTOFsplash10-004i-0092000000-b8aabbdc61f9b89ac3592017-08-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid ESI-TOF 30V, Negative-QTOFsplash10-004i-0092000000-b8aabbdc61f9b89ac3592017-08-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid ESI-TOF , Negative-QTOFsplash10-004i-0092000000-b8aabbdc61f9b89ac3592017-08-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid ESI-TOF 10V, Negative-QTOFsplash10-001i-0090000000-92096c6b229762c5295f2017-09-12HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid ESI-TOF 20V, Negative-QTOFsplash10-001i-0090000000-5fe8495a19b387bf702c2017-09-12HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid ESI-TOF 30V, Negative-QTOFsplash10-001i-0090000000-5d40399b1c736b4764452017-09-12HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid ESI-TOF , Negative-QTOFsplash10-001i-0090000000-45785aeb659bd8a092402017-09-12HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid ESI-TOF 10V, Negative-QTOFsplash10-001i-0091000000-3946ac7663105c7c27002017-09-12HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid LC-ESI-IT , negative-QTOFsplash10-001i-0090000000-ce1372cb3b5e841223492017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid LC-ESI-TOF , negative-QTOFsplash10-001i-0090000000-92096c6b229762c5295f2017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid LC-ESI-TOF , negative-QTOFsplash10-001i-0090000000-5fe8495a19b387bf702c2017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid LC-ESI-TOF , negative-QTOFsplash10-001i-0090000000-5d40399b1c736b4764452017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid 20V, Negative-QTOFsplash10-001i-0090000000-58579e8fd3d4191bcfad2021-09-20HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid 10V, Negative-QTOFsplash10-001i-0090000000-d495e7abd2148c8c35822021-09-20HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid 35V, Negative-QTOFsplash10-001i-0090000000-18d19c433b2ebed71fcf2021-09-20HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid Quattro_QQQ 10V, Positive-QTOF (Annotated)splash10-00ls-4790000000-d753b2905852ca2a8cbd2012-07-24HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid Quattro_QQQ 25V, Positive-QTOF (Annotated)splash10-0apm-9100000000-8d5c8ecf0c7a7cc3ccf62012-07-24HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid Quattro_QQQ 40V, Positive-QTOF (Annotated)splash10-0aou-9000000000-64594906d693e8a086502012-07-24HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid EI-B (Unknown) , Positive-QTOFsplash10-052f-9100000000-de078efada08e691dbb82012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Oleic acid 20V, Positive-QTOFsplash10-00l6-9450000000-10bf11713f51451a37972021-09-20HMDB team, MONAView Spectrum

NMR Spectra

Spectrum TypeDescriptionDeposition DateSourceView
Experimental 1D NMR1H NMR Spectrum (1D, 500 MHz, CDCl3, experimental)2012-12-04Wishart LabView Spectrum
Experimental 2D NMR[1H, 13C]-HSQC NMR Spectrum (2D, 600 MHz, CDCl3, experimental)2012-12-05Wishart LabView Spectrum
Biological Properties
Cellular Locations
  • Extracellular
  • Membrane (predicted from logP)
Biospecimen Locations
  • Blood
  • Cerebrospinal Fluid (CSF)
  • Feces
  • Saliva
  • Urine
Tissue Locations
  • Adipose Tissue
  • Epidermis
  • Intestine
  • Liver
  • Pancreas
  • Placenta
  • Prostate
  • Skeletal Muscle
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
BloodDetected and Quantified11.42 +/- 1.67 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified122 +/- 56 uMAdult (>18 years old)BothNormal details
BloodDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Normal		 details
BloodDetected but not QuantifiedNot QuantifiedAdult (>18 years old)BothNormal details
BloodDetected and Quantified346.950 +/- 38.943 uMAdult (>18 years old)Male
Normal		 details
BloodDetected and Quantified332.789 +/- 49.564 uMAdult (>18 years old)Male
Normal		 details
BloodDetected and Quantified339.869 +/- 42.484 uMAdult (>18 years old)Male
Normal		 details
BloodDetected and Quantified339.869 +/- 31.863 uMAdult (>18 years old)Male
Normal		 details
BloodDetected and Quantified130 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified131 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified158 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified191 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified202 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified236 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified240 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified246 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified248 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified257 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified267 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified284 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified476.384 +/- 146.817 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified401.329 +/- 90.915 uMAdult (>18 years old)FemaleNormal details
BloodDetected and Quantified49.243 +/- 19.314 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified37.0 +/- 5.7 uMAdult (>18 years old)BothNormal
    • Geigy Scientific ...
 details
BloodDetected and Quantified32.5-41.3 uMAdult (>18 years old)FemaleNormal
    • Geigy Scientific ...
 details
BloodDetected and Quantified2135.4 +/- 665.5 uMAdult (>18 years old)Not Specified
Normal		 details
BloodDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Normal		 details
BloodDetected and Quantified80.3 +/- 9.331 uMAdult (>18 years old)BothNormal details
Cerebrospinal Fluid (CSF)Detected and Quantified36.0 +/- 36.0 uMAdult (>18 years old)Not SpecifiedNormal details
FecesDetected but not QuantifiedNot QuantifiedNot SpecifiedNot Specified
Normal		 details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Normal		 details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Normal		 details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)BothNormal details
FecesDetected but not QuantifiedNot QuantifiedChildren (1-13 years old)BothNormal details
FecesDetected but not QuantifiedNot QuantifiedNot SpecifiedNot Specified
Normal		 details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Normal		 details
FecesDetected but not QuantifiedNot QuantifiedInfant (0-1 year old)Not AvailableNormal details
FecesDetected and Quantified55.0518 +/- 80.0463 nmol/g wet fecesNot SpecifiedNot Specified
Normal		 details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Normal		 details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Normal		 details
FecesDetected but not QuantifiedNot QuantifiedInfant (0-1 year old)Both
Normal		 details
FecesDetected but not QuantifiedNot QuantifiedInfant (0-1 year old)Not Specified
Normal		 details
FecesDetected but not QuantifiedNot QuantifiedInfant (0-1 year old)Not Specified
Normal		 details
SalivaDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Male
Normal		 details
SalivaDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Not SpecifiedNormal details
SalivaDetected but not QuantifiedNot QuantifiedAdult (>18 years old)BothNormal details
UrineDetected but not QuantifiedNot QuantifiedAdult (>18 years old)BothNormal details
UrineDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Normal		 details
UrineDetected and Quantified5.2 (0.3-13) umol/mmol creatinineAdult (>18 years old)BothNormal details
UrineDetected and Quantified0.16 +/- 0.08 umol/mmol creatinineAdult (>18 years old)BothNormal
    • Geigy Scientific ...
 details
Abnormal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
BloodDetected and Quantified10.22 +/- 1.33 uMAdult (>18 years old)FemaleGestational diabetes mellitus (GDM) details
BloodDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Lung cancer		 details
BloodDetected but not QuantifiedNot QuantifiedAdult (>18 years old)BothColorectal cancer details
BloodDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Schizophrenia		 details
BloodDetected and Quantified2365.1 +/- 844.5 uMAdult (>18 years old)Not Specified
Isovaleric acidemia		 details
BloodDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Schizophrenia		 details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Colorectal cancer		 details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Colorectal cancer		 details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)BothColorectal Cancer details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)BothCCD details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)BothIleal Crohn's disease details
FecesDetected but not QuantifiedNot QuantifiedNewborn (0-30 days old)Not Specified
Premature neonates		 details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Colorectal cancer		 details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)BothColorectal cancer details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Colorectal cancer		 details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)BothColorectal cancer details
Associated Disorders and Diseases
Disease References
Gestational diabetes
  1. Min Y, Ghebremeskel K, Lowy C, Thomas B, Crawford MA: Adverse effect of obesity on red cell membrane arachidonic and docosahexaenoic acids in gestational diabetes. Diabetologia. 2004 Jan;47(1):75-81. Epub 2003 Nov 22. [PubMed:14634727 ]
Lung Cancer
  1. Chen Y, Ma Z, Min L, Li H, Wang B, Zhong J, Dai L: Biomarker identification and pathway analysis by serum metabolomics of lung cancer. Biomed Res Int. 2015;2015:183624. doi: 10.1155/2015/183624. Epub 2015 Apr 16. [PubMed:25961003 ]
Schizophrenia
  1. Xuan J, Pan G, Qiu Y, Yang L, Su M, Liu Y, Chen J, Feng G, Fang Y, Jia W, Xing Q, He L: Metabolomic profiling to identify potential serum biomarkers for schizophrenia and risperidone action. J Proteome Res. 2011 Dec 2;10(12):5433-43. doi: 10.1021/pr2006796. Epub 2011 Nov 8. [PubMed:22007635 ]
  2. Al Awam K, Haussleiter IS, Dudley E, Donev R, Brune M, Juckel G, Thome J: Multiplatform metabolome and proteome profiling identifies serum metabolite and protein signatures as prospective biomarkers for schizophrenia. J Neural Transm (Vienna). 2015 Aug;122 Suppl 1:S111-22. doi: 10.1007/s00702-014-1224-0. Epub 2014 May 1. [PubMed:24789758 ]
Isovaleric acidemia
  1. Dercksen M, Kulik W, Mienie LJ, Reinecke CJ, Wanders RJ, Duran M: Polyunsaturated fatty acid status in treated isovaleric acidemia patients. Eur J Clin Nutr. 2016 Oct;70(10):1123-1126. doi: 10.1038/ejcn.2016.100. Epub 2016 Jun 22. [PubMed:27329611 ]
Colorectal cancer
  1. Weir TL, Manter DK, Sheflin AM, Barnett BA, Heuberger AL, Ryan EP: Stool microbiome and metabolome differences between colorectal cancer patients and healthy adults. PLoS One. 2013 Aug 6;8(8):e70803. doi: 10.1371/journal.pone.0070803. Print 2013. [PubMed:23940645 ]
  2. Ni Y, Xie G, Jia W: Metabonomics of human colorectal cancer: new approaches for early diagnosis and biomarker discovery. J Proteome Res. 2014 Sep 5;13(9):3857-70. doi: 10.1021/pr500443c. Epub 2014 Aug 14. [PubMed:25105552 ]
  3. Brown DG, Rao S, Weir TL, O'Malia J, Bazan M, Brown RJ, Ryan EP: Metabolomics and metabolic pathway networks from human colorectal cancers, adjacent mucosa, and stool. Cancer Metab. 2016 Jun 6;4:11. doi: 10.1186/s40170-016-0151-y. eCollection 2016. [PubMed:27275383 ]
  4. Sinha R, Ahn J, Sampson JN, Shi J, Yu G, Xiong X, Hayes RB, Goedert JJ: Fecal Microbiota, Fecal Metabolome, and Colorectal Cancer Interrelations. PLoS One. 2016 Mar 25;11(3):e0152126. doi: 10.1371/journal.pone.0152126. eCollection 2016. [PubMed:27015276 ]
  5. Goedert JJ, Sampson JN, Moore SC, Xiao Q, Xiong X, Hayes RB, Ahn J, Shi J, Sinha R: Fecal metabolomics: assay performance and association with colorectal cancer. Carcinogenesis. 2014 Sep;35(9):2089-96. doi: 10.1093/carcin/bgu131. Epub 2014 Jul 18. [PubMed:25037050 ]
  6. Wang X, Wang J, Rao B, Deng L: Gut flora profiling and fecal metabolite composition of colorectal cancer patients and healthy individuals. Exp Ther Med. 2017 Jun;13(6):2848-2854. doi: 10.3892/etm.2017.4367. Epub 2017 Apr 20. [PubMed:28587349 ]
Associated OMIM IDs
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB012858
KNApSAcK IDC00001232
Chemspider ID393217
KEGG Compound IDC00712
BioCyc IDOLEATE-CPD
BiGG IDNot Available
Wikipedia LinkOleic_acid
METLIN ID190
PubChem Compound445639
PDB IDNot Available
ChEBI ID16196
Food Biomarker OntologyNot Available
VMH IDOCDCEA
MarkerDB IDMDB00029979
Good Scents IDNot Available
References
Synthesis ReferenceHu, Sheng; Yuan, Ji-rong; Zhu, Jin; Yin, Ying-sui. Preparation of high-purity oleic acid by selective reaction. Yingyong Huagong (2005), 34(12), 748-750, 753.
Material Safety Data Sheet (MSDS)Download (PDF)
General References
  1. Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, Yu J, Laxman B, Mehra R, Lonigro RJ, Li Y, Nyati MK, Ahsan A, Kalyana-Sundaram S, Han B, Cao X, Byun J, Omenn GS, Ghosh D, Pennathur S, Alexander DC, Berger A, Shuster JR, Wei JT, Varambally S, Beecher C, Chinnaiyan AM: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4. doi: 10.1038/nature07762. [PubMed:19212411 ]
  2. Hoffmann GF, Meier-Augenstein W, Stockler S, Surtees R, Rating D, Nyhan WL: Physiology and pathophysiology of organic acids in cerebrospinal fluid. J Inherit Metab Dis. 1993;16(4):648-69. [PubMed:8412012 ]
  3. Takahashi K, Rytting JH: Novel approach to improve permeation of ondansetron across shed snake skin as a model membrane. J Pharm Pharmacol. 2001 Jun;53(6):789-94. [PubMed:11428654 ]
  4. Jensen MD: Gender differences in regional fatty acid metabolism before and after meal ingestion. J Clin Invest. 1995 Nov;96(5):2297-303. [PubMed:7593616 ]
  5. Russell AP, Somm E, Debigare R, Hartley O, Richard D, Gastaldi G, Melotti A, Michaud A, Giacobino JP, Muzzin P, LeBlanc P, Maltais F: COPD results in a reduction in UCP3 long mRNA and UCP3 protein content in types I and IIa skeletal muscle fibers. J Cardiopulm Rehabil. 2004 Sep-Oct;24(5):332-9. [PubMed:15602154 ]
  6. Crocker I, Lawson N, Daniels I, Baker P, Fletcher J: Significance of fatty acids in pregnancy-induced immunosuppression. Clin Diagn Lab Immunol. 1999 Jul;6(4):587-93. [PubMed:10391868 ]
  7. Colette C, Percheron C, Pares-Herbute N, Michel F, Pham TC, Brillant L, Descomps B, Monnier L: Exchanging carbohydrates for monounsaturated fats in energy-restricted diets: effects on metabolic profile and other cardiovascular risk factors. Int J Obes Relat Metab Disord. 2003 Jun;27(6):648-56. [PubMed:12833107 ]
  8. Christophe AB, De Greyt WF, Delanghe JR, Huyghebaert AD: Substituting enzymatically interesterified butter for native butter has no effect on lipemia or lipoproteinemia in Man. Ann Nutr Metab. 2000;44(2):61-7. [PubMed:10970994 ]
  9. de la Maza MP, Hirsch S, Nieto S, Petermann M, Bunout D: Fatty acid composition of liver total lipids in alcoholic patients with and without liver damage. Alcohol Clin Exp Res. 1996 Nov;20(8):1418-22. [PubMed:8947319 ]
  10. Droke EA, Briske-Anderson M, Lukaski HC: Fatty acids alter monolayer integrity, paracellular transport, and iron uptake and transport in Caco-2 cells. Biol Trace Elem Res. 2003 Dec;95(3):219-32. [PubMed:14665727 ]
  11. Valjakka-Koskela R, Hirvonen J, Monkkonen J, Kiesvaara J, Antila S, Lehtonen L, Urtti A: Transdermal delivery of levosimendan. Eur J Pharm Sci. 2000 Oct;11(4):343-50. [PubMed:11033078 ]
  12. Jones AE, Stolinski M, Smith RD, Murphy JL, Wootton SA: Effect of fatty acid chain length and saturation on the gastrointestinal handling and metabolic disposal of dietary fatty acids in women. Br J Nutr. 1999 Jan;81(1):37-43. [PubMed:10341674 ]
  13. Thielitz A, Helmdach M, Ropke EM, Gollnick H: Lipid analysis of follicular casts from cyanoacrylate strips as a new method for studying therapeutic effects of antiacne agents. Br J Dermatol. 2001 Jul;145(1):19-27. [PubMed:11453902 ]
  14. Richieri GV, Ogata RT, Kleinfeld AM: Equilibrium constants for the binding of fatty acids with fatty acid-binding proteins from adipocyte, intestine, heart, and liver measured with the fluorescent probe ADIFAB. J Biol Chem. 1994 Sep 30;269(39):23918-30. [PubMed:7929039 ]
  15. Lima WP, Carnevali LC Jr, Eder R, Costa Rosa LF, Bacchi EM, Seelaender MC: Lipid metabolism in trained rats: effect of guarana (Paullinia cupana Mart.) supplementation. Clin Nutr. 2005 Dec;24(6):1019-28. Epub 2005 Sep 22. [PubMed:16182414 ]
  16. Vinggaard AM, Provost JJ, Exton JH, Hansen HS: Arf and RhoA regulate both the cytosolic and the membrane-bound phospholipase D from human placenta. Cell Signal. 1997 Feb;9(2):189-96. [PubMed:9113419 ]
  17. Mittendorfer B, Liem O, Patterson BW, Miles JM, Klein S: What does the measurement of whole-body fatty acid rate of appearance in plasma by using a fatty acid tracer really mean? Diabetes. 2003 Jul;52(7):1641-8. [PubMed:12829627 ]
  18. Cater NB, Denke MA: Behenic acid is a cholesterol-raising saturated fatty acid in humans. Am J Clin Nutr. 2001 Jan;73(1):41-4. [PubMed:11124748 ]
  19. Bajaj M, Suraamornkul S, Romanelli A, Cline GW, Mandarino LJ, Shulman GI, DeFronzo RA: Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty Acyl-CoAs and insulin action in type 2 diabetic patients. Diabetes. 2005 Nov;54(11):3148-53. [PubMed:16249438 ]
  20. Andersen TC, Pedersen JF, Nordentoft T, Olsen O: Fat and mesenteric blood flow. Scand J Gastroenterol. 1999 Sep;34(9):894-7. [PubMed:10522608 ]
  21. Ayala-Bravo HA, Quintanar-Guerrero D, Naik A, Kalia YN, Cornejo-Bravo JM, Ganem-Quintanar A: Effects of sucrose oleate and sucrose laureate on in vivo human stratum corneum permeability. Pharm Res. 2003 Aug;20(8):1267-73. [PubMed:12948025 ]
  22. Elshenawy S, Pinney SE, Stuart T, Doulias PT, Zura G, Parry S, Elovitz MA, Bennett MJ, Bansal A, Strauss JF 3rd, Ischiropoulos H, Simmons RA: The Metabolomic Signature of the Placenta in Spontaneous Preterm Birth. Int J Mol Sci. 2020 Feb 4;21(3). pii: ijms21031043. doi: 10.3390/ijms21031043. [PubMed:32033212 ]

Only showing the first 10 proteins. There are 11 proteins in total.

Show all enzymes and transporters

Enzymes

Enzyme Details
1. Fatty acid synthase
General function:
Involved in transferase activity
Specific function:
Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
Gene Name:
FASN
Uniprot ID:
P49327
Molecular weight:
273424.06
Reactions
Oleoyl-[acyl-carrier-protein] + Water → [acyl-carrier-protein] + Oleic aciddetails
Enzyme Details
2. Bile acid-CoA:amino acid N-acyltransferase
General function:
Involved in thiolester hydrolase activity
Specific function:
Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.
Gene Name:
BAAT
Uniprot ID:
Q14032
Molecular weight:
46298.865
Enzyme Details
3. Cytosolic acyl coenzyme A thioester hydrolase
General function:
Lipid transport and metabolism
Specific function:
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May play an important physiological function in brain. May play a regulatory role by modulating the cellular levels of fatty acyl-CoA ligands for certain transcription factors as well as the substrates for fatty acid metabolizing enzymes, contributing to lipid homeostasis. Has broad specificity, active towards fatty acyl-CoAs with chain-lengths of C8-C18. Has a maximal activity toward palmitoyl-CoA.
Gene Name:
ACOT7
Uniprot ID:
O00154
Molecular weight:
40454.945
Reactions
Oleoyl-CoA + Water → Coenzyme A + Oleic aciddetails
Enzyme Details
4. Acyl-coenzyme A thioesterase 2, mitochondrial
General function:
Involved in thiolester hydrolase activity
Specific function:
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Displays high levels of activity on medium- and long chain acyl CoAs.
Gene Name:
ACOT2
Uniprot ID:
P49753
Molecular weight:
53218.02
Reactions
Oleoyl-CoA + Water → Coenzyme A + Oleic aciddetails
Enzyme Details
5. Acyl-coenzyme A thioesterase 4
General function:
Involved in thiolester hydrolase activity
Specific function:
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs.
Gene Name:
ACOT4
Uniprot ID:
Q8N9L9
Molecular weight:
46326.09
Reactions
Oleoyl-CoA + Water → Coenzyme A + Oleic aciddetails
Enzyme Details
6. Acyl-coenzyme A thioesterase 8
General function:
Involved in acyl-CoA thioesterase activity
Specific function:
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxisome proliferation.
Gene Name:
ACOT8
Uniprot ID:
O14734
Molecular weight:
35914.02
Enzyme Details
7. Fatty-acid amide hydrolase 1
General function:
Involved in carbon-nitrogen ligase activity, with glutamine as amido-N-donor
Specific function:
Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates.
Gene Name:
FAAH
Uniprot ID:
O00519
Molecular weight:
63065.28
Reactions
Oleamide + Water → Oleic acid + Ammoniadetails
Enzyme Details
8. 2-acylglycerol O-acyltransferase 2
General function:
Involved in transferase activity, transferring acyl groups other than amino-acyl groups
Specific function:
Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity.
Gene Name:
MOGAT2
Uniprot ID:
Q3SYC2
Molecular weight:
38195.285
Enzyme Details
9. Fatty-acid amide hydrolase 2
General function:
Involved in carbon-nitrogen ligase activity, with glutamine as amido-N-donor
Specific function:
Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates.
Gene Name:
FAAH2
Uniprot ID:
Q6GMR7
Molecular weight:
58303.115
Reactions
Oleamide + Water → Oleic acid + Ammoniadetails
Enzyme Details
10. Acyl-coenzyme A thioesterase 1
General function:
Involved in thiolester hydrolase activity
Specific function:
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16 (By similarity).
Gene Name:
ACOT1
Uniprot ID:
Q86TX2
Molecular weight:
46276.96
Reactions
Oleoyl-CoA + Water → Coenzyme A + Oleic aciddetails

Only showing the first 10 proteins. There are 11 proteins in total.

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