We are currently updating the database - data may be missing for the next 10 minutes. We apologize for any inconvenience.

Human Metabolome Database Version 2.5

 

Showing metabocard for Taurochenodesoxycholic acid (HMDB00951)

Legend: metabolite field enzyme field

Version 2.5
Creation Date 2005-11-16 15:48:42
Update Date 2009-08-26 13:48:32
Accession Number HMDB00951
Secondary Accession Numbers Not Available
Common Name Taurochenodesoxycholic acid
Description Taurochenodesoxycholic acid is a bile acid formed in the liver by conjugation of chenodeoxycholate with taurine, usually as the sodium salt. Bile acids are steroid acids found predominantly in bile of mammals. The distinction between different bile acids is minute, depends only on presence or absence of hydroxyl groups on positions 3, 7, and 12. Bile acids are physiological detergents that facilitate excretion, absorption, and transport of fats and sterols in the intestine and liver. Bile acids are also steroidal amphipathic molecules derived from the catabolism of cholesterol. They modulate bile flow and lipid secretion, are essential for the absorption of dietary fats and vitamins, and have been implicated in the regulation of all the key enzymes involved in cholesterol homeostasis. Bile acids recirculate through the liver, bile ducts, small intestine and portal vein to form an enterohepatic circuit. They exist as anions at physiological pH and, consequently, require a carrier for transport across the membranes of the enterohepatic tissues. The unique detergent properties of bile acids are essential for the digestion and intestinal absorption of hydrophobic nutrients. Bile acids have potent toxic properties (e.g., membrane disruption) and there are a plethora of mechanisms to limit their accumulation in blood and tissues. (PMID: 11316487, 16037564, 12576301, 11907135)
Synonyms
  1. 12-Deoxycholyltaurine
  2. 12-Desoxycholyltaurine
  3. 3a,7a-Dihydroxy-N-(2-sulfoethyl)-5b-cholan-24-amide
  4. Chenodeoxycholyltaurine
  5. Chenyltaurine
  6. N-(3a,7a-dihydroxy-5b-cholan-24-oyl)-Taurine
  7. Taurochenodeoxycholate
  8. Taurochenodeoxycholic acid
  9. Taurochenodesoxycholate
  10. Taurochenodesoxycholic acid
Chemical IUPAC Name 2-[4-(3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoylamino]ethanesulfonic acid
Chemical Formula C26H45NO6S
Chemical Structure Structure
Chemical Taxonomy
Kingdom
  • Organic
Super Class
  • Cholesterols and derivatives
Class
  • Bile Acids
Sub Class
  • Taurinated bile acids
Family
  • Microbial Metabolite
Species
  • secondary alcohol
  • secondary carboxylic acid amide
  • sulfonic acid
Biofunction
  • Hormones, Membrane component
Application
—
Source
  • Endogenous
Average Molecular Weight 499.704
Monoisotopic Molecular Weight 499.296753
Isomeric SMILES C[C@H](CCC(=O)NCCS(O)(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Canonical SMILES CC(CCC(=O)NCCS(O)(=O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C
KEGG Compound ID C05465 Link Image
BioCyc ID CHENODEOXYCHOLOYLTAURINE Link Image
BiGG ID 45864 Link Image
Wikipedia Link Not Available
NuGOwiki Link HMDB00951 Link Image
Metagene Link HMDB00951 Link Image
METLIN ID 5897 Link Image
PubChem Compound 10591 Link Image
PubChem Substance 153883 Link Image
ChEBI ID 16525 Link Image
CAS Registry Number 516-35-8
InChI Identifier InChI=1/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20+,21+,22?,24+,25+,26-/m1/s1
Synthesis Reference Karbach Ia I; Rybak P G Synthesis of conjugated bile acids. Ukrainskii biokhimicheskii zhurnal (1979), 51(1), 76-9.
Melting Point (Experimental) Not Available
Experimental Water Solubility Not Available Source: PhysProp
Predicted Water Solubility 7.48e-03 mg/mL [Predicted by ALOGPS] Calculated using ALOGPS
Physiological Charge -1
State Solid
Experimental LogP/Hydrophobicity Not Available Source: PhysProp
Predicted LogP/Hydrophobicity 1.38 [Predicted by ALOGPS]; 3.5 [Predicted by PubChem via XLOGP] Calculated using ALOGPS
Material Safety Data Sheet (MSDS) Not Available
MOL File Show
SDF File Show
PDB File Show
2D Structure
3D Structure
Experimental PDB ID Not Available
Experimental 1H NMR Spectrum Not Available
Experimental 13C NMR Spectrum Not Available
Experimental 13C HSQC Spectrum Not Available
Predicted 1H NMR Spectrum Show Image
Show Peaklist
Predicted 13C NMR Spectrum Show Image
Show Peaklist
Mass Spectrum Not Available
Simplified TOCSY Spectrum Not Available
BMRB Spectrum Not Available
Cellular Location
  • Membrane (Predicted from LogP)
  • Cytoplasm
  • Extracellular
  • peroxisome
Biofluid Location
  • Bile
  • Blood
  • Urine
Tissue Location Not Available
Concentrations (Normal)
Biofluid Bile
Value >0.01 uM
Age Adult:>18 yrs old
Sex Both
Patient information Normal
Comments Not Available
References
  • Bloch CA, Watkins JB: Determination of conjugated bile acids in human bile and duodenal fluid by reverse-phase high-performance liquid chromatography. J Lipid Res. 1978 May;19(4):510-3. [PubMed Link Image]
Biofluid Blood
Value 0.30 +/- 0.08 uM
Age Adult:>18 yrs old
Sex Both
Patient information Normal
Comments Not Available
References
  • Geigy Scientific Tables, 8th Rev edition, pp. 165-177. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp., Basel, Switzerland c1981-1992.
Biofluid Urine
Value 0.00065 +/- 0.0019 umol/mmol creatinine
Age Children:1-13 yrs old
Sex Both
Patient information Normal
Comments Not Available
References
  • Nittono H, Obinata K, Nakatsu N, Watanabe T, Niijima S, Sasaki H, Arisaka O, Kato H, Yabuta K, Miyano T: Sulfated and nonsulfated bile acids in urine of patients with biliary atresia: analysis of bile acids by high-performance liquid chromatography. J Pediatr Gastroenterol Nutr. 1986 Jan;5(1):23-9. [PubMed Link Image]
Concentrations (Abnormal)
Biofluid Urine
Value 0.013 +/- 0.021 umol/mmol creatinine
Age Adult:>18 yrs old
Sex Both
Condition Biliary atresia
Comments Not Available
References
  • Nittono H, Obinata K, Nakatsu N, Watanabe T, Niijima S, Sasaki H, Arisaka O, Kato H, Yabuta K, Miyano T: Sulfated and nonsulfated bile acids in urine of patients with biliary atresia: analysis of bile acids by high-performance liquid chromatography. J Pediatr Gastroenterol Nutr. 1986 Jan;5(1):23-9. [PubMed Link Image]
Associated Disorders
Condition References
Biliary atresia
  • Nittono H, Obinata K, Nakatsu N, Watanabe T, Niijima S, Sasaki H, Arisaka O, Kato H, Yabuta K, Miyano T: Sulfated and nonsulfated bile acids in urine of patients with biliary atresia: analysis of bile acids by high-performance liquid chromatography. J Pediatr Gastroenterol Nutr. 1986 Jan;5(1):23-9. [PubMed Link Image]
OMIM ID
Pathways
Name SMPDB Link KEGG Link
Bile Acid Biosynthesis SMP00035 Link Image map00120 Link Image
General References
  1. Bloch CA, Watkins JB: Determination of conjugated bile acids in human bile and duodenal fluid by reverse-phase high-performance liquid chromatography. J Lipid Res. 1978 May;19(4):510-3. [PubMed Link Image]
  2. Ijare OB, Somashekar BS, Jadegoud Y, Nagana Gowda GA: 1H and 13C NMR characterization and stereochemical assignments of bile acids in aqueous media. Lipids. 2005 Oct;40(10):1031-41. [PubMed Link Image]
  3. Schwenk M, Hofmann AF, Carlson GL, Carter JA, Coulston F, Greim H: Bile acid conjugation in the chimpanzee: effective sulfation of lithocholic acid. Arch Toxicol. 1978 Apr 27;40(2):109-18. [PubMed Link Image]
  4. Pouwels MJ, Tack CJ, Span PN, Olthaar AJ, Sweep CG, Huvers FC, Lutterman JA, Hermus AR: Role of hexosamines in insulin resistance and nutrient sensing in human adipose and muscle tissue. J Clin Endocrinol Metab. 2004 Oct;89(10):5132-7. [PubMed Link Image]
  5. Makino I, Shinozaki K, Nakagawa S, Mashimo K: Measurement of sulfated and nonsulfated bile acids in human serum and urine. J Lipid Res. 1974 Mar;15(2):132-8. [PubMed Link Image]
  6. Bolhuis PA, Sinaasappel M: Bile acid clearance and biocompatibility of XAD-4 haemoperfusion. Int J Artif Organs. 1978 May;1(3):135-41. [PubMed Link Image]
  7. Roda A, Pellicciari R, Polimeni C, Cerre C, Forti GC, Sadeghpour B, Sapigni E, Gioacchini AM, Natalini B: Metabolism, pharmacokinetics, and activity of a new 6-fluoro analogue of ursodeoxycholic acid in rats and hamsters. Gastroenterology. 1995 Apr;108(4):1204-14. [PubMed Link Image]
Metabolic Enzymes
  1. Choloylglycine hydrolase (EC 3.5.1.24)
  2. Choloylglycine hydrolase (EC 3.5.1.24)
  3. Choloylglycine hydrolase (EC 3.5.1.24)
  4. Choloylglycine hydrolase
  5. Bile salt hydrolase
  6. Bile salt hydrolase (EC 3.5.1.24)
  7. Choloylglycine hydrolase
  8. Putative choloylglycine hydrolase (EC 3.5.1.24)
  9. Choloylglycine hydrolase
  10. Choloylglycine hydrolase
  11. Choloylglycine hydrolase (EC 3.5.1.24)
  12. Choloylglycine hydrolase family protein
  13. Choloylglycine hydrolase family protein
  14. EF0040 (Choloylglycine hydrolase) (Choloylglycine hydrolase family protein)
  15. Conjugated bile acid hydrolase
Enzyme 1 [top]
Enzyme 1 ID 15841
Enzyme 1 Name Choloylglycine hydrolase (EC 3.5.1.24)
Enzyme 1 Synonyms Not Available
Enzyme 1 Gene Name bsh2
Enzyme 1 Protein Sequence >Choloylglycine hydrolase (EC 3.5.1.24) 
MCTSLTYTNSHGGHFLARTMDFNVDFETRIMFMPRHYRVTGDLGDFTTTYGFIGAGRQLN
HEIFTDGVNECGVSIAALYFPNHAIYQPHSNQDKIDLAPHDFVAWVLGKITSVADLRERV
KDVQLISSTAELINEIPPLHFIISDQTGETAVLEPTSGELRLLNNPVGVLTNSPNLKWQL
QNLSKYGTLTNTERPLNKFINYQPGSQGPGTGALGLPGDYTSMSRFARTVFLKHYAQVPA
TTTDTVNLLQHILNAVTIPKGAKVAANGQATYTEYRSYMDLNHQTYALELYENPGVIQQV
NLTDHLLEKQTVPLEYVLSRTPHVQLLTPDVATLPAAH
Enzyme 1 Number of Residues 338
Enzyme 1 Molecular Weight 37542
Enzyme 1 Theoretical pI 6.39
Enzyme 1 GO Classification Not Available
Enzyme 1 General Function Cell wall/membrane/envelope biogenesis
Enzyme 1 Specific Function Not Available
Enzyme 1 Pathways Not Available
Enzyme 1 Reactions
  • 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine [RN:R05835] ALL_REAC R05835
  • (other) R02797 R03975 R03977 R04486 R04487
Enzyme 1 Pfam Domain Function
Enzyme 1 Signals
  • None
Enzyme 1 Transmembrane Regions
  • None
Enzyme 1 Essentiality Not Available
Enzyme 1 GenBank ID Protein Not Available
Enzyme 1 UniProtKB/Swiss-Prot ID Q890F5 Link Image
Enzyme 1 UniProtKB/Swiss-Prot Entry Name Q890F5_LACPL Link Image
Enzyme 1 PDB ID Not Available
Enzyme 1 Cellular Location Not Available
Enzyme 1 Gene Sequence Not Available
Enzyme 1 GenBank Gene ID AL935252 Link Image
Enzyme 1 GeneCard ID Not Available
Enzyme 1 GenAtlas ID Not Available
Enzyme 1 HGNC ID Not Available
Enzyme 1 Chromosome Location Not Available
Enzyme 1 Locus Not Available
Enzyme 1 SNPs SNPJam Report Link Image
Enzyme 1 General References
  1. Kleerebezem M, Boekhorst J, van Kranenburg R, Molenaar D, Kuipers OP, Leer R, Tarchini R, Peters SA, Sandbrink HM, Fiers MW, Stiekema W, Lankhorst RM, Bron PA, Hoffer SM, Groot MN, Kerkhoven R, de Vries M, Ursing B, de Vos WM, Siezen RJ: Complete genome sequence of Lactobacillus plantarum WCFS1. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1990-5. Epub 2003 Feb 3. [PubMed Link Image]
Enzyme 1 Metabolite References Not Available
Enzyme 2 [top]
Enzyme 2 ID 15842
Enzyme 2 Name Choloylglycine hydrolase (EC 3.5.1.24)
Enzyme 2 Synonyms Not Available
Enzyme 2 Gene Name bsh4
Enzyme 2 Protein Sequence >Choloylglycine hydrolase (EC 3.5.1.24) 
MCTSLTYLDTDNHRYFARTMDFPTTTPWRPIFLPRRYPWPTGLATTRMTQYAILGGGRLP
DHFKACLMADSINEAGLVCAELYLPHAVEYATQSQVNQINLTPQAFINWALGEHQSVAAV
IADLPSVNLVGASWGDDTGEVYPFHWYLSDAHTSAVIEPTGGPLTVQPNPAGVLTNTPVL
SDHQRRLNRYLAVSGNQITTATRQAAQHVIQTKQPLPSGPIPTDRFIHMALRRLGTPQLA
PQQVPTTLFRWLQEVSLPYHADRRHLISHNYTHYRCLITLATRTYRFIPRTTGHEQRLTL
TPEMATTWRTPYLFPAD
Enzyme 2 Number of Residues 317
Enzyme 2 Molecular Weight 35767
Enzyme 2 Theoretical pI 8.59
Enzyme 2 GO Classification Not Available
Enzyme 2 General Function Cell wall/membrane/envelope biogenesis
Enzyme 2 Specific Function Not Available
Enzyme 2 Pathways Not Available
Enzyme 2 Reactions
  • 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine [RN:R05835] ALL_REAC R05835
  • (other) R02797 R03975 R03977 R04486 R04487
Enzyme 2 Pfam Domain Function
Enzyme 2 Signals
  • None
Enzyme 2 Transmembrane Regions
  • None
Enzyme 2 Essentiality Not Available
Enzyme 2 GenBank ID Protein Not Available
Enzyme 2 UniProtKB/Swiss-Prot ID Q88UC9 Link Image
Enzyme 2 UniProtKB/Swiss-Prot Entry Name Q88UC9_LACPL Link Image
Enzyme 2 PDB ID Not Available
Enzyme 2 Cellular Location Not Available
Enzyme 2 Gene Sequence Not Available
Enzyme 2 GenBank Gene ID AL935259 Link Image
Enzyme 2 GeneCard ID Not Available
Enzyme 2 GenAtlas ID Not Available
Enzyme 2 HGNC ID Not Available
Enzyme 2 Chromosome Location Not Available
Enzyme 2 Locus Not Available
Enzyme 2 SNPs SNPJam Report Link Image
Enzyme 2 General References
  1. Kleerebezem M, Boekhorst J, van Kranenburg R, Molenaar D, Kuipers OP, Leer R, Tarchini R, Peters SA, Sandbrink HM, Fiers MW, Stiekema W, Lankhorst RM, Bron PA, Hoffer SM, Groot MN, Kerkhoven R, de Vries M, Ursing B, de Vos WM, Siezen RJ: Complete genome sequence of Lactobacillus plantarum WCFS1. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1990-5. Epub 2003 Feb 3. [PubMed Link Image]
Enzyme 2 Metabolite References Not Available
Enzyme 3 [top]
Enzyme 3 ID 15843
Enzyme 3 Name Choloylglycine hydrolase (EC 3.5.1.24)
Enzyme 3 Synonyms Not Available
Enzyme 3 Gene Name bsh3
Enzyme 3 Protein Sequence >Choloylglycine hydrolase (EC 3.5.1.24) 
MCTSLTIQTTAGDQFLARTMDFAFELGGRPVAIPRNHHFDSVTNADGFDSPYSFVGTGRD
LNGYIFVDGVNEHGVSAAALYFSGQAHFTQQTKAGKVNLAPHEVLMWILGNVKSTAELGE
RIADLNVMEAAAPLLNIVVPLHWIISDKSGSTYVLELENDGVHYMKNPVGVMTNTPDFEW
HLKNLSNYVNLQPGPHPSRQYGDMTVNPFGPGTGALGMPGDYTSVARFVRTVFMREHTDA
VTTDAEAVNALSHMLNSVEIPKGVKMQDNGTPDYTQYRAYMSMNEPAFYMQPYADQTITR
VELTPALMTAAQPTEFELKTTQQFRLAN
Enzyme 3 Number of Residues 328
Enzyme 3 Molecular Weight 36167
Enzyme 3 Theoretical pI 5.12
Enzyme 3 GO Classification Not Available
Enzyme 3 General Function Cell wall/membrane/envelope biogenesis
Enzyme 3 Specific Function Not Available
Enzyme 3 Pathways Not Available
Enzyme 3 Reactions
  • 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine [RN:R05835] ALL_REAC R05835
  • (other) R02797 R03975 R03977 R04486 R04487
Enzyme 3 Pfam Domain Function
Enzyme 3 Signals
  • None
Enzyme 3 Transmembrane Regions
  • None
Enzyme 3 Essentiality Not Available
Enzyme 3 GenBank ID Protein Not Available
Enzyme 3 UniProtKB/Swiss-Prot ID Q88SP0 Link Image
Enzyme 3 UniProtKB/Swiss-Prot Entry Name Q88SP0_LACPL Link Image
Enzyme 3 PDB ID Not Available
Enzyme 3 Cellular Location Not Available
Enzyme 3 Gene Sequence Not Available
Enzyme 3 GenBank Gene ID AL935261 Link Image
Enzyme 3 GeneCard ID Not Available
Enzyme 3 GenAtlas ID Not Available
Enzyme 3 HGNC ID Not Available
Enzyme 3 Chromosome Location Not Available
Enzyme 3 Locus Not Available
Enzyme 3 SNPs SNPJam Report Link Image
Enzyme 3 General References
  1. Kleerebezem M, Boekhorst J, van Kranenburg R, Molenaar D, Kuipers OP, Leer R, Tarchini R, Peters SA, Sandbrink HM, Fiers MW, Stiekema W, Lankhorst RM, Bron PA, Hoffer SM, Groot MN, Kerkhoven R, de Vries M, Ursing B, de Vos WM, Siezen RJ: Complete genome sequence of Lactobacillus plantarum WCFS1. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1990-5. Epub 2003 Feb 3. [PubMed Link Image]
Enzyme 3 Metabolite References Not Available
Enzyme 4 [top]
Enzyme 4 ID 15844
Enzyme 4 Name Choloylglycine hydrolase
Enzyme 4 Synonyms
  1. Conjugated bile acid hydrolase
  2. CBAH
  3. Bile salt hydrolase
Enzyme 4 Gene Name cbh
Enzyme 4 Protein Sequence >Choloylglycine hydrolase 
MCTAITYQSYNNYFGRNFDYEISYNEMVTITPRKYPLVFRKVENLDHHYAIIGITADVES
YPLYYDAMNEKGLCIAGLNFAGYADYKKYDADKVNITPFELIPWLLGQFSSVREVKKNIQ
KLNLVNINFSEQLPLSPLHWLVADKQESIVIESVKEGLKIYDNPVGVLTNNPNFDYQLFN
LNNYRALSNSTPQNSFSEKVDLDSYSRGMGGLGLPGDLSSMSRFVRAAFTKLNSLSMQTE
SGSVSQFFHILGSVEQQKGLCEVTDGKYEYTIYSSCCDMDKGVYYYRTYDNSQINSVSLN
HEHLDTTELISYPLRSEAQYYAVN
Enzyme 4 Number of Residues 324
Enzyme 4 Molecular Weight 37042
Enzyme 4 Theoretical pI 4.92
Enzyme 4 GO Classification Not Available
Enzyme 4 General Function Cell wall/membrane/envelope biogenesis
Enzyme 4 Specific Function The enzyme catalyzes the degradation of conjugated bile acids in the mammalian gut
Enzyme 4 Pathways Not Available
Enzyme 4 Reactions Not Available
Enzyme 4 Pfam Domain Function
Enzyme 4 Signals
  • None
Enzyme 4 Transmembrane Regions
  • None
Enzyme 4 Essentiality Not Available
Enzyme 4 GenBank ID Protein Not Available
Enzyme 4 UniProtKB/Swiss-Prot ID Q06115 Link Image
Enzyme 4 UniProtKB/Swiss-Prot Entry Name CBH_LACPL Link Image
Enzyme 4 PDB ID Not Available
Enzyme 4 Cellular Location Not Available
Enzyme 4 Gene Sequence Not Available
Enzyme 4 GenBank Gene ID S51638 Link Image
Enzyme 4 GeneCard ID Not Available
Enzyme 4 GenAtlas ID Not Available
Enzyme 4 HGNC ID Not Available
Enzyme 4 Chromosome Location Not Available
Enzyme 4 Locus Not Available
Enzyme 4 SNPs SNPJam Report Link Image
Enzyme 4 General References
  1. Christiaens H, Leer RJ, Pouwels PH, Verstraete W: Cloning and expression of a conjugated bile acid hydrolase gene from Lactobacillus plantarum by using a direct plate assay. Appl Environ Microbiol. 1992 Dec;58(12):3792-8. [PubMed Link Image]
  2. Kleerebezem M, Boekhorst J, van Kranenburg R, Molenaar D, Kuipers OP, Leer R, Tarchini R, Peters SA, Sandbrink HM, Fiers MW, Stiekema W, Lankhorst RM, Bron PA, Hoffer SM, Groot MN, Kerkhoven R, de Vries M, Ursing B, de Vos WM, Siezen RJ: Complete genome sequence of Lactobacillus plantarum WCFS1. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1990-5. Epub 2003 Feb 3. [PubMed Link Image]
Enzyme 4 Metabolite References Not Available
Enzyme 5 [top]
Enzyme 5 ID 15845
Enzyme 5 Name Bile salt hydrolase
Enzyme 5 Synonyms Not Available
Enzyme 5 Gene Name bshA
Enzyme 5 Protein Sequence >Bile salt hydrolase 
MCTSIIFSPKDHYFGRNLDLEITFGQQVVITPRNYTFKFRKMPSLKKHYAMIGISLDMDD
YPLYFDATNEKGLGMAGLNYPGNATYYEEKENKDNIASFEFIPWILGQCSTISEVKDLLS
RINIADLNFSEKMQASSLHWLIADKTGTSLVVETDKDGMHIYDNPVGCLTNNPQFPKQLF
NLNNYADVSPKMPKNNFSDKVNMAGYSRGLGSHNLPGGMDSESRFVRVAFNKFNAPIAET
EEENIDTYFHILHSVEQQKGLDEVGPNSFEYTIYSDGTNLDKGIFYYTTYSNKQINVVDM
NKEDLDSSNLITYDMLDKTKFNHQN
Enzyme 5 Number of Residues 325
Enzyme 5 Molecular Weight 37081
Enzyme 5 Theoretical pI 4.86
Enzyme 5 GO Classification Not Available
Enzyme 5 General Function Cell wall/membrane/envelope biogenesis
Enzyme 5 Specific Function Not Available
Enzyme 5 Pathways Not Available
Enzyme 5 Reactions Not Available
Enzyme 5 Pfam Domain Function
Enzyme 5 Signals
  • None
Enzyme 5 Transmembrane Regions
  • None
Enzyme 5 Essentiality Not Available
Enzyme 5 GenBank ID Protein Not Available
Enzyme 5 UniProtKB/Swiss-Prot ID Q5FKM3 Link Image
Enzyme 5 UniProtKB/Swiss-Prot Entry Name Q5FKM3_LACAC Link Image
Enzyme 5 PDB ID Not Available
Enzyme 5 Cellular Location Not Available
Enzyme 5 Gene Sequence Not Available
Enzyme 5 GenBank Gene ID CP000033 Link Image
Enzyme 5 GeneCard ID Not Available
Enzyme 5 GenAtlas ID Not Available
Enzyme 5 HGNC ID Not Available
Enzyme 5 Chromosome Location Not Available
Enzyme 5 Locus Not Available
Enzyme 5 SNPs SNPJam Report Link Image
Enzyme 5 General References Not Available
Enzyme 5 Metabolite References Not Available
Enzyme 6 [top]
Enzyme 6 ID 15846
Enzyme 6 Name Bile salt hydrolase (EC 3.5.1.24)
Enzyme 6 Synonyms Not Available
Enzyme 6 Gene Name bshB
Enzyme 6 Protein Sequence >Bile salt hydrolase (EC 3.5.1.24) 
MCTSICYNPNDHYFGRNLDYEIAYGQKVVIVPRNYEFKYREMPSQKMHYAFIGVSVVNDD
YPLLCDAINEKGLGIAGLNFQGPNHYFPKIEGKKNIASFELMPYLLSNCENTDDVKEILD
NANILNISFSANYPAADLHWILSDKAGKSIVVESTNSGLHIYDNPVNVLTNNPEFPDQLI
KLSDYADVTPHNPKNTLVPNVDLNLYSRGLGTHHLPGGMDSSSRFVKVAFVLAHTPQGKN
EVENVTNYFHILHSVEQPDGLDEVEDNRYEYTMYTDCMNLDKGILYFTTYDNNRINAVDM
HKADLDSEDLICYDLFKKQDIEYMN
Enzyme 6 Number of Residues 325
Enzyme 6 Molecular Weight 37057
Enzyme 6 Theoretical pI 4.60
Enzyme 6 GO Classification Not Available
Enzyme 6 General Function Cell wall/membrane/envelope biogenesis
Enzyme 6 Specific Function Not Available
Enzyme 6 Pathways Not Available
Enzyme 6 Reactions
  • 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine [RN:R05835] ALL_REAC R05835
  • (other) R02797 R03975 R03977 R04486 R04487
Enzyme 6 Pfam Domain Function
Enzyme 6 Signals
  • None
Enzyme 6 Transmembrane Regions
  • None
Enzyme 6 Essentiality Not Available
Enzyme 6 GenBank ID Protein Not Available
Enzyme 6 UniProtKB/Swiss-Prot ID Q5FK51 Link Image
Enzyme 6 UniProtKB/Swiss-Prot Entry Name Q5FK51_LACAC Link Image
Enzyme 6 PDB ID Not Available
Enzyme 6 Cellular Location Not Available
Enzyme 6 Gene Sequence Not Available
Enzyme 6 GenBank Gene ID CP000033 Link Image
Enzyme 6 GeneCard ID Not Available
Enzyme 6 GenAtlas ID Not Available
Enzyme 6 HGNC ID Not Available
Enzyme 6 Chromosome Location Not Available
Enzyme 6 Locus Not Available
Enzyme 6 SNPs SNPJam Report Link Image
Enzyme 6 General References Not Available
Enzyme 6 Metabolite References Not Available
Enzyme 7 [top]
Enzyme 7 ID 15847
Enzyme 7 Name Choloylglycine hydrolase
Enzyme 7 Synonyms Not Available
Enzyme 7 Gene Name Not Available
Enzyme 7 Protein Sequence >Choloylglycine hydrolase 
MCTGVRFSDDEGNTYFGRNLDWSFSYGETILVTPRGYHYDTVFGAGGKAKPNAVIGVGVV
MADRPMYFDCANEHGLAIAGLNFPGYASFVHEPVEGTENVATFEFPLWVARNFDSVDEVE
EALRNVTLVSQIVPGQQESLLHWFIGDGKRSIVVEQMADGMHVHHDDVDVLTNQPTFDFH
MENLRNYMCVSNEMAEPTSWGKASLTAWGAGVGMHGIPGDVSSPSRFVRVAYTNAHYPQQ
NDEAANVSRLFHTLGSVQMVDGMAKMGDGQFERTLFTSGYSSKTNTYYMNTYDDPAIRSY
AMADYDMDSSELISVAR
Enzyme 7 Number of Residues 317
Enzyme 7 Molecular Weight 35125
Enzyme 7 Theoretical pI 4.49
Enzyme 7 GO Classification Not Available
Enzyme 7 General Function Cell wall/membrane/envelope biogenesis
Enzyme 7 Specific Function Not Available
Enzyme 7 Pathways Not Available
Enzyme 7 Reactions Not Available
Enzyme 7 Pfam Domain Function
Enzyme 7 Signals
  • None
Enzyme 7 Transmembrane Regions
  • None
Enzyme 7 Essentiality Not Available
Enzyme 7 GenBank ID Protein Not Available
Enzyme 7 UniProtKB/Swiss-Prot ID Q8G653 Link Image
Enzyme 7 UniProtKB/Swiss-Prot Entry Name Q8G653_BIFLO Link Image
Enzyme 7 PDB ID Not Available
Enzyme 7 Cellular Location Not Available
Enzyme 7 Gene Sequence Not Available
Enzyme 7 GenBank Gene ID AE014295 Link Image
Enzyme 7 GeneCard ID Not Available
Enzyme 7 GenAtlas ID Not Available
Enzyme 7 HGNC ID Not Available
Enzyme 7 Chromosome Location Not Available
Enzyme 7 Locus Not Available
Enzyme 7 SNPs Not Available
Enzyme 7 General References
  1. Schell MA, Karmirantzou M, Snel B, Vilanova D, Berger B, Pessi G, Zwahlen MC, Desiere F, Bork P, Delley M, Pridmore RD, Arigoni F: The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14422-7. Epub 2002 Oct 15. [PubMed Link Image]
Enzyme 7 Metabolite References Not Available
Enzyme 8 [top]
Enzyme 8 ID 15848
Enzyme 8 Name Putative choloylglycine hydrolase (EC 3.5.1.24)
Enzyme 8 Synonyms Not Available
Enzyme 8 Gene Name cbh
Enzyme 8 Protein Sequence >Putative choloylglycine hydrolase (EC 3.5.1.24) 
MKSKDGATVVARTIEWAESVMNCMYVVVPRAQELQSLTPSGMDGLKFRAKHGFVGLAVEQ
KEFVVEGMNEKGLSAGLYYFPNYGRYPVYDAAQRDKSLADFQLVSYVLAECSTVDEVKEA
LSQVRVINIDPRSSTVHWRFTEASGRQVVLEIVNEMMNFYDNPLGVLTNSPGLEWHWTNL
NNYINLQPGTLPEHNFGPLEPKSFGHGSGLLGLPGDFTPPSRFVRATFFQLTAPQQPDAK
GSVFQAFHILNNFDIPTGSEQPWGKASANVPSATQFTVACDIRDQKVYYRTMYNSNIRCI
DLKTINFDNVKYQADPLDETKEQPVEMKVIK
Enzyme 8 Number of Residues 331
Enzyme 8 Molecular Weight 37168
Enzyme 8 Theoretical pI 5.68
Enzyme 8 GO Classification Not Available
Enzyme 8 General Function Cell wall/membrane/envelope biogenesis
Enzyme 8 Specific Function Not Available
Enzyme 8 Pathways Not Available
Enzyme 8 Reactions
  • 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine [RN:R05835] ALL_REAC R05835
  • (other) R02797 R03975 R03977 R04486 R04487
Enzyme 8 Pfam Domain Function
Enzyme 8 Signals
  • None
Enzyme 8 Transmembrane Regions
  • None
Enzyme 8 Essentiality Not Available
Enzyme 8 GenBank ID Protein Not Available
Enzyme 8 UniProtKB/Swiss-Prot ID Q5LF84 Link Image
Enzyme 8 UniProtKB/Swiss-Prot Entry Name Q5LF84_BACFN Link Image
Enzyme 8 PDB ID Not Available
Enzyme 8 Cellular Location Not Available
Enzyme 8 Gene Sequence Not Available
Enzyme 8 GenBank Gene ID CR626927 Link Image
Enzyme 8 GeneCard ID Not Available
Enzyme 8 GenAtlas ID Not Available
Enzyme 8 HGNC ID Not Available
Enzyme 8 Chromosome Location Not Available
Enzyme 8 Locus Not Available
Enzyme 8 SNPs SNPJam Report Link Image
Enzyme 8 General References Not Available
Enzyme 8 Metabolite References Not Available
Enzyme 9 [top]
Enzyme 9 ID 15849
Enzyme 9 Name Choloylglycine hydrolase
Enzyme 9 Synonyms Not Available
Enzyme 9 Gene Name Not Available
Enzyme 9 Protein Sequence >Choloylglycine hydrolase 
MRRKIMMATLIVIAVNFIWSGQPVKACTRAVYIGPDNMVITGRTMDWKEDIQSNLYLFPR
GIKRAGYNKGNTVEWISKYGSIVATGYDIGTCDGMNEKGLVASLLFLPESIYVRRNDTRP
VMGISIWTQYVLDNFATVSEAVEELKKQTFRIDAPDMPNGSASTLHMAITDETGNSAVLE
YIDGNLIIHEGKEYQVMTNSPRYDLQLAVNDYWKEVGGLNMLPGTNRSSDRFVRASFYIH
AIPQTSDAKIAVPSVLSVMRNVSVPFGITTPDKPYISSTRWRSVSDQKNRVYYFESTLTP
NLFWIDLHKVDFSPNASIKKLSLTHGEVYAGDVVKDFKDSRSFTFMFELPK
Enzyme 9 Number of Residues 351
Enzyme 9 Molecular Weight 39630
Enzyme 9 Theoretical pI 8.54
Enzyme 9 GO Classification Not Available
Enzyme 9 General Function Cell wall/membrane/envelope biogenesis
Enzyme 9 Specific Function Not Available
Enzyme 9 Pathways Not Available
Enzyme 9 Reactions Not Available
Enzyme 9 Pfam Domain Function
Enzyme 9 Signals
  • None
Enzyme 9 Transmembrane Regions
  • None
Enzyme 9 Essentiality Not Available
Enzyme 9 GenBank ID Protein Not Available
Enzyme 9 UniProtKB/Swiss-Prot ID Q64PP5 Link Image
Enzyme 9 UniProtKB/Swiss-Prot Entry Name Q64PP5_BACFR Link Image
Enzyme 9 PDB ID Not Available
Enzyme 9 Cellular Location Not Available
Enzyme 9 Gene Sequence Not Available
Enzyme 9 GenBank Gene ID AP006841 Link Image
Enzyme 9 GeneCard ID Not Available
Enzyme 9 GenAtlas ID Not Available
Enzyme 9 HGNC ID Not Available
Enzyme 9 Chromosome Location Not Available
Enzyme 9 Locus Not Available
Enzyme 9 SNPs Not Available
Enzyme 9 General References Not Available
Enzyme 9 Metabolite References Not Available
Enzyme 10 [top]
Enzyme 10 ID 15850
Enzyme 10 Name Choloylglycine hydrolase
Enzyme 10 Synonyms
  1. Conjugated bile acid hydrolase
  2. CBAH
  3. Bile salt hydrolase
Enzyme 10 Gene Name cbh
Enzyme 10 Protein Sequence >Choloylglycine hydrolase 
MCTGLALETKDGLHLFGRNMDIEYSFNQSIIFIPRNFKCVNKSNKKELTTKYAVLGMGTI
FDDYPTFADGMNEKGLGCAGLNFPVYVSYSKEDIEGKTNIPVYNFLLWVLANFSSVEEVK
EALKNANIVDIPISENIPNTTLHWMISDITGKSIVVEQTKEKLNVFDNNIGVLTNSPTFD
WHVANLNQYVGLRYNQVPEFKLGDQSLTALGQGTGLVGLPGDFTPASRFIRVAFLRDAMI
KNDKDSIDLIEFFHILNNVAMVRGSTRTVEEKSDLTQYTSCMCLEKGIYYYNTYENNQIN
AIDMNKENLDGNEIKTYKYNKTLSINHVN
Enzyme 10 Number of Residues 329
Enzyme 10 Molecular Weight 37186
Enzyme 10 Theoretical pI 5.07
Enzyme 10 GO Classification Not Available
Enzyme 10 General Function Cell wall/membrane/envelope biogenesis
Enzyme 10 Specific Function The enzyme catalyzes the degradation of conjugated bile acids in the mammalian gut
Enzyme 10 Pathways Not Available
Enzyme 10 Reactions Not Available
Enzyme 10 Pfam Domain Function
Enzyme 10 Signals
  • None
Enzyme 10 Transmembrane Regions
  • None
Enzyme 10 Essentiality Not Available
Enzyme 10 GenBank ID Protein Not Available
Enzyme 10 UniProtKB/Swiss-Prot ID P54965 Link Image
Enzyme 10 UniProtKB/Swiss-Prot Entry Name CBH_CLOPE Link Image
Enzyme 10 PDB ID 2BJF Link Image
Enzyme 10 PDB File Show
Enzyme 10 3D Structure
Enzyme 10 Cellular Location Not Available
Enzyme 10 Gene Sequence Not Available
Enzyme 10 GenBank Gene ID U20191 Link Image
Enzyme 10 GeneCard ID Not Available
Enzyme 10 GenAtlas ID Not Available
Enzyme 10 HGNC ID Not Available
Enzyme 10 Chromosome Location Not Available
Enzyme 10 Locus Not Available
Enzyme 10 SNPs SNPJam Report Link Image
Enzyme 10 General References
  1. Coleman JP, Hudson LL: Cloning and characterization of a conjugated bile acid hydrolase gene from Clostridium perfringens. Appl Environ Microbiol. 1995 Jul;61(7):2514-20. [PubMed Link Image]
  2. Shimizu T, Ohtani K, Hirakawa H, Ohshima K, Yamashita A, Shiba T, Ogasawara N, Hattori M, Kuhara S, Hayashi H: Complete genome sequence of Clostridium perfringens, an anaerobic flesh-eater. Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):996-1001. Epub 2002 Jan 15. [PubMed Link Image]
Enzyme 10 Metabolite References Not Available
Enzyme 11 [top]
Enzyme 11 ID 15851
Enzyme 11 Name Choloylglycine hydrolase (EC 3.5.1.24)
Enzyme 11 Synonyms Not Available
Enzyme 11 Gene Name Not Available
Enzyme 11 Protein Sequence >Choloylglycine hydrolase (EC 3.5.1.24) 
MCTGLALETKDGLHLFGRNMDIEYSFNQSIIFIPRNFKCVNKSNKKELTTKYAVLGMGTI
FDDYPTFADGMNEKGLGCAGLNFPVYVSYSKEDIEGKTNIPVYNFLLWVLANFSSVEEVK
EALKNANIVDIPISENIPNTTLHWMISDITGKSIVVEQTKEKLNVFDNNIGVLTNSPTFD
WHVANLNQYVGLRYNQVPEFKLGDQSLTALGQGTGLVGLPGDFTPASRFIRVAFLRDAMI
KNDKDSIDLIEFFHILNNVAMVRGSTRTVEEKSDLTQYTSCMCLEKGIYYYNTYENNQIN
AIDMNKENLDGNEIKTYKYNKTLSINHVN
Enzyme 11 Number of Residues 329
Enzyme 11 Molecular Weight 37186
Enzyme 11 Theoretical pI 5.07
Enzyme 11 GO Classification
Function
  • DNA binding
  • binding
  • nucleic acid binding
Process
  • cell organization and biogenesis
  • cellular physiological process
  • cellular protein metabolism
  • chromosome organization and biogenesis
  • chromosome organization and biogenesis (sensu Eukaryota)
  • macromolecule metabolism
  • metabolism
  • nucleosome assembly
  • organelle organization and biogenesis
  • physiological process
  • protein complex assembly
  • protein metabolism
Component
  • intracellular membrane-bound organelle
  • membrane-bound organelle
  • nucleosome
  • nucleus
  • organelle
  • protein complex
Enzyme 11 General Function Cell wall/membrane/envelope biogenesis
Enzyme 11 Specific Function Not Available
Enzyme 11 Pathways Not Available
Enzyme 11 Reactions
  • 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine [RN:R05835] ALL_REAC R05835
  • (other) R02797 R03975 R03977 R04486 R04487
Enzyme 11 Pfam Domain Function
Enzyme 11 Signals
  • None
Enzyme 11 Transmembrane Regions
  • None
Enzyme 11 Essentiality Not Available
Enzyme 11 GenBank ID Protein Not Available
Enzyme 11 UniProtKB/Swiss-Prot ID Q0TT83 Link Image
Enzyme 11 UniProtKB/Swiss-Prot Entry Name Q0TT83_CLOP1 Link Image
Enzyme 11 PDB ID 2BJF Link Image
Enzyme 11 PDB File Show
Enzyme 11 3D Structure
Enzyme 11 Cellular Location Not Available
Enzyme 11 Gene Sequence Not Available
Enzyme 11 GenBank Gene ID CP000246 Link Image
Enzyme 11 GeneCard ID Not Available
Enzyme 11 GenAtlas ID Not Available
Enzyme 11 HGNC ID Not Available
Enzyme 11 Chromosome Location Not Available
Enzyme 11 Locus Not Available
Enzyme 11 SNPs Not Available
Enzyme 11 General References Not Available
Enzyme 11 Metabolite References Not Available
Enzyme 12 [top]
Enzyme 12 ID 15852
Enzyme 12 Name Choloylglycine hydrolase family protein
Enzyme 12 Synonyms Not Available
Enzyme 12 Gene Name Not Available
Enzyme 12 Protein Sequence >Choloylglycine hydrolase family protein 
MCTHIHISSVNNNLYWGRTLDTSFNPFEVGSKITIVPRNFTLETQSKPWKTKYAFLGINL
CGSTLFFDGVNEKGLAGGLLFLKACTWDKKENIEKQGLIAINSGEIVTWILSNFESVSDI
KNNISKVVVTSDDIPSLGELGKGNPITAHYTFTDKMGESVVLEPTNHGHFRVFDNTVGVM
ANDPTFDWHMTNLANYLQVQGFNKQQNHLNSKTVITPISNGTGLLGLPGDYTSPSRFVRV
AYLRNLIGDITDEEAPARLFSILNSVWVPKDVERFYEDKKESDFSSYMCAYDQSLGKLYL
RVFNDIDTKEFSLENVKENELVTYSI
Enzyme 12 Number of Residues 326
Enzyme 12 Molecular Weight 36672
Enzyme 12 Theoretical pI 5.40
Enzyme 12 GO Classification Not Available
Enzyme 12 General Function Cell wall/membrane/envelope biogenesis
Enzyme 12 Specific Function Not Available
Enzyme 12 Pathways Not Available
Enzyme 12 Reactions Not Available
Enzyme 12 Pfam Domain Function
Enzyme 12 Signals
  • None
Enzyme 12 Transmembrane Regions
  • None
Enzyme 12 Essentiality Not Available
Enzyme 12 GenBank ID Protein Not Available
Enzyme 12 UniProtKB/Swiss-Prot ID Q0TRE6 Link Image
Enzyme 12 UniProtKB/Swiss-Prot Entry Name Q0TRE6_CLOP1 Link Image
Enzyme 12 PDB ID Not Available
Enzyme 12 Cellular Location Not Available
Enzyme 12 Gene Sequence Not Available
Enzyme 12 GenBank Gene ID CP000246 Link Image
Enzyme 12 GeneCard ID Not Available
Enzyme 12 GenAtlas ID Not Available
Enzyme 12 HGNC ID Not Available
Enzyme 12 Chromosome Location Not Available
Enzyme 12 Locus Not Available
Enzyme 12 SNPs Not Available
Enzyme 12 General References Not Available
Enzyme 12 Metabolite References Not Available
Enzyme 13 [top]
Enzyme 13 ID 15853
Enzyme 13 Name Choloylglycine hydrolase family protein
Enzyme 13 Synonyms Not Available
Enzyme 13 Gene Name Not Available
Enzyme 13 Protein Sequence >Choloylglycine hydrolase family protein 
MCTHIHISSVNNNLYWGRTLDTSFNPFEVGSKITIVPRNFTLQTESNPWKTKYSFLGINL
CGSTLFFDGVNEKGLAGGLLFLKACTWDKKENIEKQGLTAINSGEIVPWILSNFESVSDI
KNNISKVVVTPDDIPSLGELGKGNPITAHYTFTDKMGESVVLEPTDHGHFRVFDNNVGVM
ANDPTFDWHMTNLANYLQVQGFNKQQNHLNSKTVITPISNGTGLLGLPGDYTSPSRFVRV
AYLRNLIGDVTDEEAPARLFSILNSVWVPKDVERFYEDKKESDFSSYMCAYDQKLGKLYL
RVFNDIDTKEFSLENVKENELVTYSI
Enzyme 13 Number of Residues 326
Enzyme 13 Molecular Weight 36709
Enzyme 13 Theoretical pI 5.21
Enzyme 13 GO Classification Not Available
Enzyme 13 General Function Cell wall/membrane/envelope biogenesis
Enzyme 13 Specific Function Not Available
Enzyme 13 Pathways Not Available
Enzyme 13 Reactions Not Available
Enzyme 13 Pfam Domain Function
Enzyme 13 Signals
  • None
Enzyme 13 Transmembrane Regions
  • None
Enzyme 13 Essentiality Not Available
Enzyme 13 GenBank ID Protein Not Available
Enzyme 13 UniProtKB/Swiss-Prot ID Q0STT0 Link Image
Enzyme 13 UniProtKB/Swiss-Prot Entry Name Q0STT0_CLOPS Link Image
Enzyme 13 PDB ID Not Available
Enzyme 13 Cellular Location Not Available
Enzyme 13 Gene Sequence Not Available
Enzyme 13 GenBank Gene ID CP000312 Link Image
Enzyme 13 GeneCard ID Not Available
Enzyme 13 GenAtlas ID Not Available
Enzyme 13 HGNC ID Not Available
Enzyme 13 Chromosome Location Not Available
Enzyme 13 Locus Not Available
Enzyme 13 SNPs Not Available
Enzyme 13 General References Not Available
Enzyme 13 Metabolite References Not Available
Enzyme 14 [top]
Enzyme 14 ID 15854
Enzyme 14 Name EF0040 (Choloylglycine hydrolase) (Choloylglycine hydrolase family protein)
Enzyme 14 Synonyms Not Available
Enzyme 14 Gene Name ef0040
Enzyme 14 Protein Sequence >EF0040 (Choloylglycine hydrolase) (Choloylglycine hydrolase family protein) 
MCTAITYVSKDHYFGRNFDYEISYNEVVTITPRNYKFSFREVGNLDHHFAIIGIAAGIAD
YPLYYDAINEKGLGMAGLNFSGYADYKKIEEGKENVSPFEFIPWVLGQCSTVDEAKKLLK
NLNLVNINFSDELPLSPLHWLLADKEQSIVVESTKEGLRVFDNPVGVLTNNPTFDYQLFN
LNNYRVLSTRTPKNNFSDQIELDIYSRGMGGIGLPGDLSSVSRFVKATFTKLNSVSRSSE
YESISQFFHILSSVEQQKGLCDVGDEKYEYTIYSSCCNLEKGIYYYRTYDNSQITAVDMN
KENLEKDSLIVYPMVETQQINYAN
Enzyme 14 Number of Residues 324
Enzyme 14 Molecular Weight 36933
Enzyme 14 Theoretical pI 4.65
Enzyme 14 GO Classification Not Available
Enzyme 14 General Function Cell wall/membrane/envelope biogenesis
Enzyme 14 Specific Function Not Available
Enzyme 14 Pathways Not Available
Enzyme 14 Reactions Not Available
Enzyme 14 Pfam Domain Function
Enzyme 14 Signals
  • None
Enzyme 14 Transmembrane Regions
  • None
Enzyme 14 Essentiality Not Available
Enzyme 14 GenBank ID Protein Not Available
Enzyme 14 UniProtKB/Swiss-Prot ID Q8KUA7 Link Image
Enzyme 14 UniProtKB/Swiss-Prot Entry Name Q8KUA7_ENTFA Link Image
Enzyme 14 PDB ID Not Available
Enzyme 14 Cellular Location Not Available
Enzyme 14 Gene Sequence Not Available
Enzyme 14 GenBank Gene ID AY032999 Link Image
Enzyme 14 GeneCard ID Not Available
Enzyme 14 GenAtlas ID Not Available
Enzyme 14 HGNC ID Not Available
Enzyme 14 Chromosome Location Not Available
Enzyme 14 Locus Not Available
Enzyme 14 SNPs SNPJam Report Link Image
Enzyme 14 General References
  1. Shankar N, Baghdayan AS, Gilmore MS: Modulation of virulence within a pathogenicity island in vancomycin-resistant Enterococcus faecalis. Nature. 2002 Jun 13;417(6890):746-50. [PubMed Link Image]
  2. Paulsen IT, Banerjei L, Myers GS, Nelson KE, Seshadri R, Read TD, Fouts DE, Eisen JA, Gill SR, Heidelberg JF, Tettelin H, Dodson RJ, Umayam L, Brinkac L, Beanan M, Daugherty S, DeBoy RT, Durkin S, Kolonay J, Madupu R, Nelson W, Vamathevan J, Tran B, Upton J, Hansen T, Shetty J, Khouri H, Utterback T, Radune D, Ketchum KA, Dougherty BA, Fraser CM: Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis. Science. 2003 Mar 28;299(5615):2071-4. [PubMed Link Image]
Enzyme 14 Metabolite References Not Available
Enzyme 15 [top]
Enzyme 15 ID 16696
Enzyme 15 Name Conjugated bile acid hydrolase
Enzyme 15 Synonyms Not Available
Enzyme 15 Gene Name cbaH
Enzyme 15 Protein Sequence >Conjugated bile acid hydrolase 
MCTGVRFSDDEGNTYFGRNLDWSFSYGETILVTPRGYHYDTVFGAGGKAKPNAVIGVGVV
MADRPMYFDCANEHGLAIAGLNFPGYASFVHEPVEGTENVATFEFPLWVARNFDSVDEVE
EALRNVTLVSQIVPGQQESLLHWFIGDGKRSIVVEQMADGMHVHHDDVDVLTNQPTFDFH
MENLRNYMCVSNEMAEPTSWGKASLTAWGAGVGMHGIPGDVSSPSRFVRVAYTNAHYPQQ
NDEAANVSRLFHTLGSVQMVDGMAKMGDGQFERTLFTSGYSSKTNTYYMNTYDDPAIRSY
AMADYDMDSSELISVAR
Enzyme 15 Number of Residues 317
Enzyme 15 Molecular Weight 35125
Enzyme 15 Theoretical pI 4.49
Enzyme 15 GO Classification Not Available
Enzyme 15 General Function Cell wall/membrane/envelope biogenesis
Enzyme 15 Specific Function Not Available
Enzyme 15 Pathways Not Available
Enzyme 15 Reactions Not Available
Enzyme 15 Pfam Domain Function
Enzyme 15 Signals
  • None
Enzyme 15 Transmembrane Regions
  • None
Enzyme 15 Essentiality Not Available
Enzyme 15 GenBank ID Protein Not Available
Enzyme 15 UniProtKB/Swiss-Prot ID B3DS63 Link Image
Enzyme 15 UniProtKB/Swiss-Prot Entry Name B3DS63_BIFLD Link Image
Enzyme 15 PDB ID Not Available
Enzyme 15 Cellular Location Not Available
Enzyme 15 Gene Sequence Not Available
Enzyme 15 GenBank Gene ID CP000605 Link Image
Enzyme 15 GeneCard ID Not Available
Enzyme 15 GenAtlas ID Not Available
Enzyme 15 HGNC ID Not Available
Enzyme 15 Chromosome Location Not Available
Enzyme 15 Locus Not Available
Enzyme 15 SNPs SNPJam Report Link Image
Enzyme 15 General References Not Available
Enzyme 15 Metabolite References Not Available