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Record Information
Version5.0
StatusExpected but not Quantified
Creation Date2006-05-22 14:17:53 UTC
Update Date2023-02-21 17:16:24 UTC
HMDB IDHMDB0002455
Secondary Accession Numbers
  • HMDB02455
Metabolite Identification
Common NamePyruvatoxime
DescriptionSynthetic dimer was found to react rapidly with pyruvate to form the expected oxime. 1H NMR spectrum of the purified oxime is superimposable with that arising when the dimer and pyruvate are mixed and the spectrum taken immediately thereafter. Then the mass spectrum of the reaction product of cycloserine dimer and methylpyruvate is totally consistent with the formation of a stable oxime derivative. Furthermore, when cycloserine is incubated with pyruvate the oxime derived from the dimer is found.(PMID: 2495795 ).
Structure
Thumb
Synonyms
ValueSource
2-(hydroxyimino)PropanoateHMDB
2-(hydroxyimino)Propanoic acidHMDB
2-OximinopropanoateHMDB
2-Oximinopropanoic acidHMDB, MeSH
Pyruvate oximeHMDB
Pyruvic oximeHMDB, MeSH
2-Oximinopropanoic acid, ion (1-)MeSH, HMDB
(2E)-2-(Hydroxyimino)propanoateGenerator, HMDB
PyruvatoximeMeSH
Chemical FormulaC3H5NO3
Average Molecular Weight103.0767
Monoisotopic Molecular Weight103.026943031
IUPAC Name(2E)-2-(hydroxyimino)propanoic acid
Traditional Namepyruvic oxime
CAS Registry Number2211-14-5
SMILES
C\C(=N/O)C(O)=O
InChI Identifier
InChI=1S/C3H5NO3/c1-2(4-7)3(5)6/h7H,1H3,(H,5,6)/b4-2+
InChI KeyMVGBKLTYYAYYGY-DUXPYHPUSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as ketoximes. These are organic compounds with the general formula RC(R')=NOH (R,R' = organyl).
KingdomOrganic compounds
Super ClassOrganic nitrogen compounds
ClassOrganonitrogen compounds
Sub ClassOximes
Direct ParentKetoximes
Alternative Parents
Substituents
  • Ketoxime
  • Monocarboxylic acid or derivatives
  • Carboxylic acid
  • Carboxylic acid derivative
  • Organic oxygen compound
  • Organopnictogen compound
  • Organic oxide
  • Hydrocarbon derivative
  • Organooxygen compound
  • Carbonyl group
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External DescriptorsNot Available
Ontology
Physiological effectNot Available
Disposition
ProcessNot Available
RoleNot Available
Physical Properties
StateSolid
Experimental Molecular Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water Solubility902 mg/mLNot Available
LogPNot AvailableNot Available
Experimental Chromatographic PropertiesNot Available
Predicted Molecular Properties
Predicted Chromatographic Properties
Spectra
Biological Properties
Cellular Locations
  • Cytoplasm (predicted from logP)
Biospecimen LocationsNot Available
Tissue LocationsNot Available
Pathways
Normal Concentrations
Not Available
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB023008
KNApSAcK IDNot Available
Chemspider ID4925178
KEGG Compound IDNot Available
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkNot Available
METLIN ID6687
PubChem Compound6419427
PDB IDKG7
ChEBI IDNot Available
Food Biomarker OntologyNot Available
VMH IDNot Available
MarkerDB IDNot Available
Good Scents IDNot Available
References
Synthesis ReferenceCastignetti D; Forgue C J; Sclafani L A Pathway of oxidation of pyruvic oxime by a heterotrophic nitrifier of the genus Alcaligenes: evidence against nitroethane as an intermediate. Archives of biochemistry and biophysics (1986), 250(1), 228-32.
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Perez-Sala D, Ayuso MS, Rico M, Parrilla R, Rando RR: The interaction of cycloserine with pyruvate and other biologically relevant alpha-ketoacids. Biochem Pharmacol. 1989 Apr 1;38(7):1037-44. [PubMed:2495795 ]