Record Information |
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Version | 5.0 |
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Status | Detected but not Quantified |
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Creation Date | 2021-09-11 17:06:28 UTC |
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Update Date | 2022-09-22 17:44:26 UTC |
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HMDB ID | HMDB0256585 |
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Secondary Accession Numbers | None |
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Metabolite Identification |
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Common Name | Piracetam |
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Description | Piracetam, also known as myocalm, belongs to the class of organic compounds known as alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof. Based on a literature review very few articles have been published on Piracetam. This compound has been identified in human blood as reported by (PMID: 31557052 ). Piracetam is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives. Technically Piracetam is part of the human exposome. The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health. An individual's exposure begins before birth and includes insults from environmental and occupational sources. |
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Structure | InChI=1S/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9) |
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Synonyms | Value | Source |
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Myocalm | Kegg | AbZ brand OF piracetam | MeSH | Almirall brand OF piracetam | MeSH | Alpharma brand OF piracetam | MeSH | Cerepar N | MeSH | Cuxabrain | MeSH | Hormona brand OF piracetam | MeSH | Nootropil | MeSH | Normabraïn | MeSH | Pfizer brand OF piracetam | MeSH | Piracebral | MeSH | Piracetam abz | MeSH | Piracetrop | MeSH | Pirazetam | MeSH | 2-Pyrrolidone-N-acetamide | MeSH | Gabacet | MeSH | memo-Puren | MeSH | Merckle brand OF piracetam | MeSH | Nootropyl | MeSH | Piracetam RPH | MeSH | Pyramem | MeSH | Riemser brand OF piracetam | MeSH | Avigilen | MeSH | Azupharma brand OF piracetam | MeSH | Cerebroforte | MeSH | Hexal brand OF piracetam | MeSH | Holsten brand OF piracetam | MeSH | Sanofi synthelabo brand OF piracetam | MeSH | TAD brand OF piracetam | MeSH | UCB brand OF piracetam | MeSH | Vedim brand OF piracetam | MeSH | Axonyl | MeSH | Ciclofalina | MeSH | Dinagen | MeSH | Geram | MeSH | memo Puren | MeSH | Nootrop | MeSH | Piracetam-RPH | MeSH | Pyracetam | MeSH | Rodleben brand OF piracetam | MeSH | Sinapsan | MeSH | 2-(2-Oxopyrrolidin-1-yl)ethanimidate | Generator |
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Chemical Formula | C6H10N2O2 |
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Average Molecular Weight | 142.1558 |
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Monoisotopic Molecular Weight | 142.074227574 |
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IUPAC Name | 2-(2-oxopyrrolidin-1-yl)ethanimidic acid |
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Traditional Name | piracetam |
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CAS Registry Number | Not Available |
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SMILES | OC(=N)CN1CCCC1=O |
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InChI Identifier | InChI=1S/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9) |
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InChI Key | GMZVRMREEHBGGF-UHFFFAOYSA-N |
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Chemical Taxonomy |
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Description | Belongs to the class of organic compounds known as alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof. |
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Kingdom | Organic compounds |
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Super Class | Organic acids and derivatives |
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Class | Carboxylic acids and derivatives |
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Sub Class | Amino acids, peptides, and analogues |
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Direct Parent | Alpha amino acids and derivatives |
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Alternative Parents | |
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Substituents | - Alpha-amino acid or derivatives
- N-alkylpyrrolidine
- 2-pyrrolidone
- Pyrrolidone
- Pyrrolidine
- Tertiary carboxylic acid amide
- Carboxamide group
- Lactam
- Primary carboxylic acid amide
- Azacycle
- Organoheterocyclic compound
- Organic nitrogen compound
- Hydrocarbon derivative
- Organic oxide
- Organooxygen compound
- Organonitrogen compound
- Organopnictogen compound
- Organic oxygen compound
- Carbonyl group
- Aliphatic heteromonocyclic compound
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Molecular Framework | Aliphatic heteromonocyclic compounds |
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External Descriptors | Not Available |
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Ontology |
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Physiological effect | Not Available |
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Disposition | |
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Process | Not Available |
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Role | Not Available |
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Physical Properties |
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State | Not Available |
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Experimental Molecular Properties | Property | Value | Reference |
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Melting Point | Not Available | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | Not Available | Not Available | LogP | Not Available | Not Available |
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Experimental Chromatographic Properties | Not Available |
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Predicted Molecular Properties | |
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Predicted Chromatographic Properties | Predicted Collision Cross SectionsPredicted Kovats Retention IndicesUnderivatizedDerivatizedDerivative Name / Structure | SMILES | Kovats RI Value | Column Type | Reference |
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Piracetam,2TMS,isomer #1 | C[Si](C)(C)N=C(CN1CCCC1=O)O[Si](C)(C)C | 1719.6 | Semi standard non polar | 33892256 | Piracetam,2TMS,isomer #1 | C[Si](C)(C)N=C(CN1CCCC1=O)O[Si](C)(C)C | 1654.1 | Standard non polar | 33892256 | Piracetam,2TMS,isomer #1 | C[Si](C)(C)N=C(CN1CCCC1=O)O[Si](C)(C)C | 2233.8 | Standard polar | 33892256 | Piracetam,2TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)N=C(CN1CCCC1=O)O[Si](C)(C)C(C)(C)C | 2123.4 | Semi standard non polar | 33892256 | Piracetam,2TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)N=C(CN1CCCC1=O)O[Si](C)(C)C(C)(C)C | 2084.0 | Standard non polar | 33892256 | Piracetam,2TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)N=C(CN1CCCC1=O)O[Si](C)(C)C(C)(C)C | 2322.3 | Standard polar | 33892256 |
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| GC-MS SpectraSpectrum Type | Description | Splash Key | Deposition Date | Source | View |
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Predicted GC-MS | Predicted GC-MS Spectrum - Piracetam GC-MS (Non-derivatized) - 70eV, Positive | splash10-0002-9100000000-91608c882f3d933f448d | 2021-09-24 | Wishart Lab | View Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - Piracetam GC-MS (Non-derivatized) - 70eV, Positive | Not Available | 2021-10-12 | Wishart Lab | View Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - Piracetam GC-MS (TMS_1_1) - 70eV, Positive | Not Available | 2021-11-05 | Wishart Lab | View Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - Piracetam GC-MS (TMS_1_2) - 70eV, Positive | Not Available | 2021-11-05 | Wishart Lab | View Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - Piracetam GC-MS (TBDMS_1_1) - 70eV, Positive | Not Available | 2021-11-05 | Wishart Lab | View Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - Piracetam GC-MS (TBDMS_1_2) - 70eV, Positive | Not Available | 2021-11-05 | Wishart Lab | View Spectrum |
MS/MS SpectraSpectrum Type | Description | Splash Key | Deposition Date | Source | View |
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Experimental LC-MS/MS | LC-MS/MS Spectrum - Piracetam LC-ESI-QFT , positive-QTOF | splash10-002b-9400000000-651dc28016b653b55d23 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Piracetam LC-ESI-QFT , positive-QTOF | splash10-002b-9400000000-9c47f9c6616fbfad2c93 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Piracetam LC-ESI-QFT , positive-QTOF | splash10-0002-9100000000-079c7eb43e2dcfe07d5f | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Piracetam LC-ESI-QFT , positive-QTOF | splash10-0002-9000000000-94d697783ea2c537498f | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Piracetam LC-ESI-QFT , positive-QTOF | splash10-0002-9000000000-5dd797bddeacd8764c16 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Piracetam LC-ESI-QFT , positive-QTOF | splash10-006t-9000000000-e270872ffd02b3d53ab2 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Piracetam 90V, Positive-QTOF | splash10-006t-9000000000-0e9ffa0c462ebcb24c98 | 2021-09-20 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Piracetam 75V, Positive-QTOF | splash10-0002-9000000000-d11cc02b12a44a1b0d59 | 2021-09-20 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Piracetam 45V, Positive-QTOF | splash10-0002-9100000000-f4ffa04f1852ef6412cc | 2021-09-20 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Piracetam 60V, Positive-QTOF | splash10-0002-9000000000-2059b9ff4235f06ea33e | 2021-09-20 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Piracetam 30V, Positive-QTOF | splash10-002b-9400000000-8f8228043062c25afc06 | 2021-09-20 | HMDB team, MONA | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Piracetam 10V, Positive-QTOF | splash10-0005-8900000000-155fdc4c7c8d2caf2b26 | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Piracetam 20V, Positive-QTOF | splash10-0002-9100000000-37719f73983f0ee54ead | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Piracetam 40V, Positive-QTOF | splash10-0002-9000000000-fef9a3341f7dc53b526c | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Piracetam 10V, Negative-QTOF | splash10-0006-1900000000-94ddc126d9251413a02c | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Piracetam 20V, Negative-QTOF | splash10-0006-6900000000-e744f388669024ef6d66 | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Piracetam 40V, Negative-QTOF | splash10-0006-9000000000-7c593ee3fff4a54ba40d | 2016-08-03 | Wishart Lab | View Spectrum |
NMR SpectraSpectrum Type | Description | Deposition Date | Source | View |
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Predicted 1D NMR | 1H NMR Spectrum (1D, 100 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 100 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 1000 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 1000 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 200 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 200 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 300 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 300 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 400 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 400 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 500 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 500 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 600 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 600 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 700 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 700 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 800 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 800 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 900 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 900 MHz, D2O, predicted) | 2021-10-27 | Wishart Lab | View Spectrum |
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