Record Information |
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Version | 5.0 |
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Status | Detected and Quantified |
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Creation Date | 2006-05-22 15:12:25 UTC |
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Update Date | 2022-03-07 02:49:17 UTC |
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HMDB ID | HMDB0003000 |
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Secondary Accession Numbers | |
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Metabolite Identification |
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Common Name | Lycopene |
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Description | Lycopene (molecular formula: C40H56) is a bright red carotenoid pigment. It is a phytochemical found in tomatoes and other red fruits. Lycopene is the most common carotenoid in the human body and is one of the most potent carotenoid antioxidants. Its name is derived from the tomato's species classification, Solanum lycopersicum. Lycopene is a terpene assembled from 8 isoprene units. Lycopene is the most powerful carotenoid quencher of singlet oxygen. Singlet oxygen from ultraviolet light is a primary cause of skin aging (Wikipedia ). |
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Structure | CC(C)=CCC\C(C)=C\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C=C(/C)CCC=C(C)C InChI=1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21+,36-22+,37-27+,38-28+,39-29+,40-30+ |
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Synonyms | Value | Source |
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(6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-Octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene | ChEBI | all-trans-Lycopene | ChEBI | all trans Lycopene | MeSH | LYC O mato | MeSH | Pro-lycopene | MeSH | LYCOMATO | MeSH | Pro lycopene | MeSH | (6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-Octamethyl-2,6,8,10,12,14,16,18,20,22,24,26,30-dotriacontatridecaene | HMDB | (all-e)-2,6,10,14,19,23,27,31-Octamethyl-2,6,8,10,12,14,16,18,20,22,24,26,30-dotriacontatridecaene | HMDB | trans-Lycopene | HMDB | (all-E)-Lycopene | HMDB | Lycopene | HMDB | psi,psi-Carotene | HMDB | ψ,ψ-Carotene | HMDB |
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Chemical Formula | C40H56 |
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Average Molecular Weight | 536.888 |
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Monoisotopic Molecular Weight | 536.438201803 |
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IUPAC Name | (6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene |
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Traditional Name | lycopene |
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CAS Registry Number | 502-65-8 |
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SMILES | CC(C)=CCC\C(C)=C\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C=C(/C)CCC=C(C)C |
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InChI Identifier | InChI=1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21+,36-22+,37-27+,38-28+,39-29+,40-30+ |
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InChI Key | OAIJSZIZWZSQBC-GYZMGTAESA-N |
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Chemical Taxonomy |
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Description | Belongs to the class of organic compounds known as carotenes. These are a type of unsaturated hydrocarbons containing eight consecutive isoprene units. They are characterized by the presence of two end-groups (mostly cyclohexene rings, but also cyclopentene rings or acyclic groups) linked by a long branched alkyl chain. Carotenes belonging form a subgroup of the carotenoids family. |
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Kingdom | Organic compounds |
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Super Class | Lipids and lipid-like molecules |
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Class | Prenol lipids |
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Sub Class | Tetraterpenoids |
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Direct Parent | Carotenes |
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Alternative Parents | |
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Substituents | - Carotene
- Branched unsaturated hydrocarbon
- Unsaturated aliphatic hydrocarbon
- Unsaturated hydrocarbon
- Olefin
- Acyclic olefin
- Hydrocarbon
- Aliphatic acyclic compound
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Molecular Framework | Aliphatic acyclic compounds |
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External Descriptors | |
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Ontology |
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Physiological effect | Not Available |
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Disposition | Biological locationRoute of exposureSourceExogenous- Exogenous (HMDB: HMDB0003000)
Food- Food (HMDB: HMDB0003000)
Animal originHerb and spiceVegetableFruitSoyNutCereal and cereal productPulseGourdCoffee and coffee productTeaDishBaking goodEggBeverageAquatic originConfectioneryMilk and milk productOther milk productFermented milkFermented milk productUnfermented milk- Milk (Other mammals) (FooDB: FOOD00690)
- Milk (Human) (FooDB: FOOD00666)
- Milk (Cow) (FooDB: FOOD00618)
- Cow milk, pasteurized, vitamin A + D added, 0% fat (FooDB: FOOD00889)
- Cow milk, pasteurized, vitamin A + D added, 1% fat (FooDB: FOOD00890)
- Cow milk, pasteurized, vitamin A + D added, 2% fat (FooDB: FOOD00891)
- Cow milk, pasteurized, vitamin D added, 3.25% fat (FooDB: FOOD00892)
Fat and oilCocoa and cocoa productBaby foodUnclassified food or beverageSnack
Endogenous |
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Process | |
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Role | |
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Physical Properties |
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State | Solid |
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Experimental Molecular Properties | |
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Experimental Chromatographic Properties | Not Available |
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Predicted Molecular Properties | | Show more...
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Predicted Chromatographic Properties | Predicted Collision Cross SectionsPredicted Kovats Retention IndicesUnderivatized | Show more...
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Spectra |
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| GC-MS SpectraSpectrum Type | Description | Splash Key | Deposition Date | Source | View |
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Predicted GC-MS | Predicted GC-MS Spectrum - Lycopene GC-MS (Non-derivatized) - 70eV, Positive | splash10-01b9-9111850000-7f5ee1d2f1f4dd233963 | 2017-09-01 | Wishart Lab | View Spectrum |
MS/MS SpectraSpectrum Type | Description | Splash Key | Deposition Date | Source | View |
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Experimental LC-MS/MS | LC-MS/MS Spectrum - Lycopene LC-ESI-QTOF 20V, positive-QTOF | splash10-0600-0951110000-51753e8053443b533c78 | 2020-07-21 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lycopene LC-ESI-QTOF 30V, positive-QTOF | splash10-052r-0930010000-1432649abfd5fa58010e | 2020-07-21 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lycopene 20V, Positive-QTOF | splash10-0600-0951110000-2db714bdbf8cb6620f55 | 2021-09-20 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lycopene 30V, Positive-QTOF | splash10-052r-0930010000-7441e95c28b443b57134 | 2021-09-20 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lycopene 20V, Positive-QTOF | splash10-0600-0951110000-433c80c51edf87449345 | 2021-09-20 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lycopene 30V, Positive-QTOF | splash10-052r-0930010000-79e6fe700d71dae15c5e | 2021-09-20 | HMDB team, MONA | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lycopene 10V, Positive-QTOF | splash10-000i-0333490000-4e9a5975acd39d46ed6f | 2016-08-01 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lycopene 20V, Positive-QTOF | splash10-0012-1968510000-01d32351dab7917ce5d2 | 2016-08-01 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lycopene 40V, Positive-QTOF | splash10-0159-4569500000-a5b112a0bf1e360b2480 | 2016-08-01 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lycopene 10V, Negative-QTOF | splash10-000i-0000090000-77adf3223ff2af4c4c1a | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lycopene 20V, Negative-QTOF | splash10-000i-0000090000-0b5e06bca49e37a860ef | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lycopene 40V, Negative-QTOF | splash10-014i-1859480000-4c571e364bf31d6a314e | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lycopene 10V, Positive-QTOF | splash10-000i-2235970000-73fc43e90358e2cae371 | 2021-09-23 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lycopene 20V, Positive-QTOF | splash10-0fc1-2011900000-667641d02a3eee5d267d | 2021-09-23 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lycopene 40V, Positive-QTOF | splash10-0wb9-1223900000-52a07bb8af9e23809e6e | 2021-09-23 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lycopene 10V, Negative-QTOF | splash10-000i-0100090000-4ab68b33d589aeb3b2dd | 2021-09-25 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lycopene 20V, Negative-QTOF | splash10-000i-0926580000-889c9c655f28c8c703c8 | 2021-09-25 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lycopene 40V, Negative-QTOF | splash10-0gb9-0503910000-a80f0ec28aa2775d93e0 | 2021-09-25 | Wishart Lab | View Spectrum |
| Show more...
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Biological Properties |
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Cellular Locations | - Extracellular
- Membrane (predicted from logP)
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Biospecimen Locations | |
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Tissue Locations | - Adipose Tissue
- Adrenal Gland
- Epidermis
- Fibroblasts
- Intestine
- Kidney
- Leukocyte
- Liver
- Pancreas
- Platelet
- Prostate
- Spleen
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Pathways | |
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Normal Concentrations |
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Blood | Detected and Quantified | 0.743 +/- 0.168 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.6 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.61 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.402 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.656 +/- 0.0100 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.360 +/- 0.240 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.400 +/- 0.280 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.420 +/- 0.280 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.420 +/- 0.320 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.330 +/- 0.230 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.350 +/- 0.250 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.610 +/- 0.360 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.703 +/- 0.860 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.440 +/- 0.280 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.474 +/- 0.560 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.510 +/- 0.340 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.640 +/- 0.380 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.926 +/- 0.270 uM | Adult (>18 years old) | Not Specified | Normal | | details | Blood | Detected and Quantified | 0.374 +/- 0.139 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.248 +/- 0.121 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.394 +/- 0.202 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.266 +/- 0.127 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.640 +/- 0.260 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.660 +/- 0.270 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.577 +/- 0.322 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.260 +/- 0.110 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.280 +/- 0.110 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.61 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.67 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 580 +/- 240 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.574 +/- 0.264 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.600 +/- 0.360 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.580 +/- 0.310 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.696 +/- 0.342 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.57 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.59 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.392 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.509 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.707 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.87 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.64 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.68 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.76 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.0705 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.143 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.263 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.406 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.567 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.623 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.170 +/- 0.120 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.335 +/- 0.164 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.01 (0.008-0.014) uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.576 +/- 0.309 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.630 +/- 0.280 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.695 +/- 0.274 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 1.340 +/- 0.750 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 1.560 +/- 0.640 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.169 uM | Adolescent (13-18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.177 uM | Children (1-13 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.51 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.71 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.771 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 1.24 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.320 +/- 0.120 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.434 +/- 0.186 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.527 +/- 0.237 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.531 +/- 0.237 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.563 +/- 0.231 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.585 +/- 0.338 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.590 +/- 0.220 uM | Adolescent (13-18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.631 +/- 0.371 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.658 +/- 0.341 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.760 +/- 0.320 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 759.376 +/- 318.688 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 242.136 +/- 111.755 uM | Adult (>18 years old) | Female | Normal | | details | Blood | Detected and Quantified | 0.159 uM | Adolescent (13-18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.187 uM | Children (1-13 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.5 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.74 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 1.44 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.501 +/- 0.338 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.505 +/- 0.183 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.579 +/- 0.253 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.610 +/- 0.240 uM | Adolescent (13-18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.620 +/- 0.308 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.622 +/- 0.320 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.630 +/- 0.276 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.746 +/- 0.379 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.820 +/- 0.380 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 1060 +/- 410 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 817.675 +/- 375.684 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 930 +/- 350 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 204.884 +/- 93.129 uM | Adult (>18 years old) | Male | Normal | | details | Blood | Detected and Quantified | 0.730 +/- 0.400 uM | Children (1 - 13 years old) | Not Specified | Normal | | details | Blood | Detected and Quantified | 0.34 +/- 0.12 uM | Adult (>18 years old) | Both | Normal | | details | Blood | Detected and Quantified | 0.52 +/- 0.17 uM | Adult (>18 years old) | Both | Normal | | details | Breast Milk | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Female | Normal | | details |
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Abnormal Concentrations |
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Blood | Detected and Quantified | 0.444 +/- 0.420 uM | Adult (>18 years old) | Not Specified | Obese | | details | Blood | Detected and Quantified | 0.608 +/- 0.690 uM | Adult (>18 years old) | Not Specified | Overweight | | details | Blood | Detected and Quantified | 0.009 (0.008-0.01) uM | Adult (>18 years old) | Female | Endometrial cancer | | details | Blood | Detected and Quantified | 0.560 +/- 0.290 uM | Adult (>18 years old) | Both | Type I diabetes | | details | Blood | Detected and Quantified | 0.380 +/- 0.220 uM | Children (1 - 13 years old) | Not Specified | Obese | | details | Blood | Detected and Quantified | 0.450 +/- 0.270 uM | Children (1 - 13 years old) | Not Specified | Overweight | | details |
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Associated Disorders and Diseases |
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Disease References | Endometrial cancer |
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- Jeong NH, Song ES, Lee JM, Lee KB, Kim MK, Yun YM, Lee JK, Son SK, Lee JP, Kim JH, Hur SY, Kwon YI: Preoperative levels of plasma micronutrients are related to endometrial cancer risk. Acta Obstet Gynecol Scand. 2009;88(4):434-9. doi: 10.1080/00016340902767187. [PubMed:19235557 ]
| Obesity |
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- Vioque J, Weinbrenner T, Asensio L, Castello A, Young IS, Fletcher A: Plasma concentrations of carotenoids and vitamin C are better correlated with dietary intake in normal weight than overweight and obese elderly subjects. Br J Nutr. 2007 May;97(5):977-86. [PubMed:17408529 ]
- Burrows TL, Warren JM, Colyvas K, Garg ML, Collins CE: Validation of overweight children's fruit and vegetable intake using plasma carotenoids. Obesity (Silver Spring). 2009 Jan;17(1):162-8. doi: 10.1038/oby.2008.495. Epub 2008 Nov 6. [PubMed:18997681 ]
| Diabetes mellitus type 1 |
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- Granado-Lorencio F, Olmedilla-Alonso B, Blanco-Navarro I, Botella-Romero F, Simal-Anton A: Assessment of carotenoid status and the relation to glycaemic control in type I diabetics: a follow-up study. Eur J Clin Nutr. 2006 Aug;60(8):1000-8. Epub 2006 Feb 1. [PubMed:16452910 ]
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Associated OMIM IDs | |
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External Links |
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DrugBank ID | DB11231 |
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Phenol Explorer Compound ID | Not Available |
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FooDB ID | FDB014534 |
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KNApSAcK ID | C00000911 |
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Chemspider ID | 394156 |
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KEGG Compound ID | C05432 |
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BioCyc ID | CPD1F-114 |
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BiGG ID | Not Available |
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Wikipedia Link | Lycopene |
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METLIN ID | Not Available |
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PubChem Compound | 446925 |
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PDB ID | Not Available |
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ChEBI ID | 15948 |
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Food Biomarker Ontology | Not Available |
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VMH ID | Not Available |
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MarkerDB ID | MDB00000408 |
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Good Scents ID | rw1030761 |
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References |
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Synthesis Reference | Ito, Shuichi; Yamaguchi, Yuzo. Fermentative production of lycopene. Jpn. Tokkyo Koho (1973), 5 pp. |
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Material Safety Data Sheet (MSDS) | Not Available |
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General References | - Stahl W, Schwarz W, Sundquist AR, Sies H: cis-trans isomers of lycopene and beta-carotene in human serum and tissues. Arch Biochem Biophys. 1992 Apr;294(1):173-7. [PubMed:1550343 ]
- Aust O, Stahl W, Sies H, Tronnier H, Heinrich U: Supplementation with tomato-based products increases lycopene, phytofluene, and phytoene levels in human serum and protects against UV-light-induced erythema. Int J Vitam Nutr Res. 2005 Jan;75(1):54-60. [PubMed:15830922 ]
- Sengupta A, Das S: The anti-carcinogenic role of lycopene, abundantly present in tomato. Eur J Cancer Prev. 1999 Aug;8(4):325-30. [PubMed:10493308 ]
- Porrini M, Riso P: Lymphocyte lycopene concentration and DNA protection from oxidative damage is increased in women after a short period of tomato consumption. J Nutr. 2000 Feb;130(2):189-92. [PubMed:10720168 ]
- Bohm V, Bitsch R: Intestinal absorption of lycopene from different matrices and interactions to other carotenoids, the lipid status, and the antioxidant capacity of human plasma. Eur J Nutr. 1999 Jun;38(3):118-25. [PubMed:10443333 ]
- Stahl W, von Laar J, Martin HD, Emmerich T, Sies H: Stimulation of gap junctional communication: comparison of acyclo-retinoic acid and lycopene. Arch Biochem Biophys. 2000 Jan 1;373(1):271-4. [PubMed:10620348 ]
- Kravchenko LV, Morozov SV, Beketova NA, Deryagina VP, Avren'eva LI, Tutel'yan VA: Antioxidant status of rats receiving lycopene in different doses. Bull Exp Biol Med. 2003 Apr;135(4):353-7. [PubMed:12910307 ]
- Zaripheh S, Nara TY, Nakamura MT, Erdman JW Jr: Dietary lycopene downregulates carotenoid 15,15'-monooxygenase and PPAR-gamma in selected rat tissues. J Nutr. 2006 Apr;136(4):932-8. [PubMed:16549453 ]
- Hsiao G, Wang Y, Tzu NH, Fong TH, Shen MY, Lin KH, Chou DS, Sheu JR: Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. J Lab Clin Med. 2005 Oct;146(4):216-26. [PubMed:16194683 ]
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