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Identification Taxonomy Ontology Physical properties Spectra Biological properties Concentrations Links References enzymes (9) Show 9 proteins XML

Record Information

Version

5.0

Status

Detected but not Quantified

Creation Date

2006-10-17 09:08:24 UTC

Update Date

2022-09-22 18:34:18 UTC

HMDB ID

HMDB0005023

Secondary Accession Numbers

HMDB05023

Metabolite Identification

Common Name

Zolpidem

Description

Zolpidem (sold under the brand names Ambien, Ambien CR, Stilnox, and Sublinox) is a prescription medication used for the treatment of insomnia, as well as some brain disorders. It is a short-acting nonbenzodiazepine hypnotic of the imidazopyridine class that potentiates gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by binding to GABAA receptors at the same location as benzodiazepines. It works quickly (usually within 15 minutes) and has a short half-life (two to three hours). Zolpidem has not adequately demonstrated effectiveness in maintaining sleep (unless delivered in a controlled-release form); however, it is effective in initiating sleep. Some users take zolpidem recreationally for these side effects. However, it may be less common than benzodiazepine abuse. Zolpidem can become addictive if taken for extended periods of time, due to dependence on its ability to put one to sleep or to the euphoria it can sometimes produce.

Structure

MOL 3D MOL SDF 3D SDF PDB 3D PDB SMILES InChI

HMDB0005023
     RDKit          3D
Zolpidem
 44 46  0  0  0  0  0  0  0  0999 V2000
    5.8624   -1.1046   -0.4037 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3945   -1.1767   -0.3026 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7810   -1.6640    0.8299 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4102   -1.7357    0.9361 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6165   -1.3043   -0.1297 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1816   -1.3954   -0.0362 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4450   -2.5451    0.3568 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7756   -2.3477    0.3762 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8306   -3.1851    0.6978 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1073   -2.6902    0.6214 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3232   -1.3836    0.2311 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7026   -0.8152    0.1368 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2290   -0.6040   -0.0749 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9689   -1.0748   -0.0050 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7979   -0.4580   -0.2660 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6229    0.9632   -0.7007 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1589    1.7958    0.4063 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0343    1.2829    1.5308 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0787    3.1833    0.2304 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.5385    4.0112    1.3285 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1241    3.8494   -1.0495 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2231   -0.8207   -1.2551 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6146   -0.7513   -1.3540 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3501   -2.1040   -0.3826 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.1865   -0.5786   -1.3247 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.2672   -0.5498    0.4873 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.4159   -1.9925    1.6409 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9414   -2.1165    1.8217 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6805   -4.1965    1.0009 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9859   -3.2890    0.8591 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.3259   -1.4729   -0.5031 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1463   -0.7878    1.1650 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6935    0.2020   -0.2921 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3831    0.4213   -0.3818 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0568    1.0680   -1.5526 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6556    1.3345   -0.9600 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3663    4.4753    1.7887 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1579    4.8337    0.9196 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1080    3.4119    2.0891 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8681    3.3187   -1.6740 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.8160    3.9924   -1.6036 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5761    4.8452   -0.8231 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6761   -0.4823   -2.1211 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0561   -0.3624   -2.2581 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  2  0
  3  4  1  0
  4  5  2  0
  5  6  1  0
  6  7  1  0
  7  8  2  0
  8  9  1  0
  9 10  2  0
 10 11  1  0
 11 12  1  0
 11 13  2  0
 13 14  1  0
 14 15  1  0
 15 16  1  0
 16 17  1  0
 17 18  2  0
 17 19  1  0
 19 20  1  0
 19 21  1  0
  5 22  1  0
 22 23  2  0
 23  2  1  0
 15  6  2  0
 14  8  1  0
  1 24  1  0
  1 25  1  0
  1 26  1  0
  3 27  1  0
  4 28  1  0
  9 29  1  0
 10 30  1  0
 12 31  1  0
 12 32  1  0
 12 33  1  0
 13 34  1  0
 16 35  1  0
 16 36  1  0
 20 37  1  0
 20 38  1  0
 20 39  1  0
 21 40  1  0
 21 41  1  0
 21 42  1  0
 22 43  1  0
 23 44  1  0
M  END

425
  Mrv0541 02231214402D          

 23 25  0  0  0  0            999 V2000
    3.4722    0.5743    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.7935   -0.9052    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    4.5741   -1.9816    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    4.5358    1.5287    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    4.5741   -0.6538    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0556   -1.3177    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7935   -1.7302    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.8305    0.1304    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.8806   -1.3177    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0791   -0.4927    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -0.9052    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0791   -2.1427    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2795    0.7445    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -1.7302    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2932   -2.0322    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2932   -0.6033    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6500   -0.4927    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.5307   -1.3177    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1182   -2.0322    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.1182   -0.6033    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9848    2.1427    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3431    1.6988    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.3557   -1.3177    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1 13  2  0  0  0  0
  2  5  1  0  0  0  0
  2  7  1  0  0  0  0
  2 10  1  0  0  0  0
  3  6  1  0  0  0  0
  3  7  2  0  0  0  0
  4 13  1  0  0  0  0
  4 21  1  0  0  0  0
  4 22  1  0  0  0  0
  5  6  2  0  0  0  0
  5  8  1  0  0  0  0
  6  9  1  0  0  0  0
  7 12  1  0  0  0  0
  8 13  1  0  0  0  0
  9 15  2  0  0  0  0
  9 16  1  0  0  0  0
 10 11  2  0  0  0  0
 11 14  1  0  0  0  0
 11 17  1  0  0  0  0
 12 14  2  0  0  0  0
 15 19  1  0  0  0  0
 16 20  2  0  0  0  0
 18 19  2  0  0  0  0
 18 20  1  0  0  0  0
 18 23  1  0  0  0  0
M  END
> <DATABASE_ID>
HMDB0005023

> <DATABASE_NAME>
hmdb

> <SMILES>
CN(C)C(=O)CC1=C(N=C2C=CC(C)=CN12)C1=CC=C(C)C=C1

> <INCHI_IDENTIFIER>
InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3

> <INCHI_KEY>
ZAFYATHCZYHLPB-UHFFFAOYSA-N

> <FORMULA>
C19H21N3O

> <MOLECULAR_WEIGHT>
307.3895

> <EXACT_MASS>
307.168462309

> <JCHEM_ACCEPTOR_COUNT>
2

> <JCHEM_AVERAGE_POLARIZABILITY>
35.06322364459639

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide

> <ALOGPS_LOGP>
3.15

> <JCHEM_LOGP>
3.0176268213333337

> <ALOGPS_LOGS>
-3.99

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
3

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_BASIC>
5.653587740811252

> <JCHEM_POLAR_SURFACE_AREA>
37.61000000000001

> <JCHEM_REFRACTIVITY>
93.58370000000001

> <JCHEM_ROTATABLE_BOND_COUNT>
3

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
3.13e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
zolpidem

> <JCHEM_VEBER_RULE>
1

$$$$

HMDB0005023
     RDKit          3D
Zolpidem
 44 46  0  0  0  0  0  0  0  0999 V2000
    5.8624   -1.1046   -0.4037 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3945   -1.1767   -0.3026 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7810   -1.6640    0.8299 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4102   -1.7357    0.9361 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6165   -1.3043   -0.1297 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1816   -1.3954   -0.0362 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4450   -2.5451    0.3568 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7756   -2.3477    0.3762 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8306   -3.1851    0.6978 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1073   -2.6902    0.6214 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3232   -1.3836    0.2311 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7026   -0.8152    0.1368 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2290   -0.6040   -0.0749 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9689   -1.0748   -0.0050 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7979   -0.4580   -0.2660 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6229    0.9632   -0.7007 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1589    1.7958    0.4063 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0343    1.2829    1.5308 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0787    3.1833    0.2304 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.5385    4.0112    1.3285 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1241    3.8494   -1.0495 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2231   -0.8207   -1.2551 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6146   -0.7513   -1.3540 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3501   -2.1040   -0.3826 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.1865   -0.5786   -1.3247 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.2672   -0.5498    0.4873 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.4159   -1.9925    1.6409 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9414   -2.1165    1.8217 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6805   -4.1965    1.0009 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9859   -3.2890    0.8591 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.3259   -1.4729   -0.5031 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1463   -0.7878    1.1650 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6935    0.2020   -0.2921 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3831    0.4213   -0.3818 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0568    1.0680   -1.5526 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6556    1.3345   -0.9600 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3663    4.4753    1.7887 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1579    4.8337    0.9196 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1080    3.4119    2.0891 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8681    3.3187   -1.6740 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.8160    3.9924   -1.6036 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5761    4.8452   -0.8231 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6761   -0.4823   -2.1211 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0561   -0.3624   -2.2581 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  2  0
  3  4  1  0
  4  5  2  0
  5  6  1  0
  6  7  1  0
  7  8  2  0
  8  9  1  0
  9 10  2  0
 10 11  1  0
 11 12  1  0
 11 13  2  0
 13 14  1  0
 14 15  1  0
 15 16  1  0
 16 17  1  0
 17 18  2  0
 17 19  1  0
 19 20  1  0
 19 21  1  0
  5 22  1  0
 22 23  2  0
 23  2  1  0
 15  6  2  0
 14  8  1  0
  1 24  1  0
  1 25  1  0
  1 26  1  0
  3 27  1  0
  4 28  1  0
  9 29  1  0
 10 30  1  0
 12 31  1  0
 12 32  1  0
 12 33  1  0
 13 34  1  0
 16 35  1  0
 16 36  1  0
 20 37  1  0
 20 38  1  0
 20 39  1  0
 21 40  1  0
 21 41  1  0
 21 42  1  0
 22 43  1  0
 23 44  1  0
M  END

HEADER    PROTEIN                                 23-FEB-12   NONE
TITLE     NULL                                                        
COMPND    MOLECULE: 425                                               
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   23-FEB-12         0                                  
HETATM    1  O   UNK     0       6.481   1.072   0.000  0.00  0.00           O+0
HETATM    2  N   UNK     0       7.081  -1.690   0.000  0.00  0.00           N+0
HETATM    3  N   UNK     0       8.538  -3.699   0.000  0.00  0.00           N+0
HETATM    4  N   UNK     0       8.467   2.854   0.000  0.00  0.00           N+0
HETATM    5  C   UNK     0       8.538  -1.220   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       9.437  -2.460   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       7.081  -3.230   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       9.017   0.243   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      10.977  -2.460   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       5.748  -0.920   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       4.414  -1.690   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       5.748  -4.000   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       7.988   1.390   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       4.414  -3.230   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      11.747  -3.793   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      11.747  -1.126   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       3.080  -0.920   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      14.057  -2.460   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      13.287  -3.793   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      13.287  -1.126   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       7.438   4.000   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       9.974   3.171   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0      15.597  -2.460   0.000  0.00  0.00           C+0
CONECT    1   13                                                            
CONECT    2    5    7   10                                                  
CONECT    3    6    7                                                       
CONECT    4   13   21   22                                                  
CONECT    5    2    6    8                                                  
CONECT    6    3    5    9                                                  
CONECT    7    2    3   12                                                  
CONECT    8    5   13                                                       
CONECT    9    6   15   16                                                  
CONECT   10    2   11                                                       
CONECT   11   10   14   17                                                  
CONECT   12    7   14                                                       
CONECT   13    1    4    8                                                  
CONECT   14   11   12                                                       
CONECT   15    9   19                                                       
CONECT   16    9   20                                                       
CONECT   17   11                                                            
CONECT   18   19   20   23                                                  
CONECT   19   15   18                                                       
CONECT   20   16   18                                                       
CONECT   21    4                                                            
CONECT   22    4                                                            
CONECT   23   18                                                            
MASTER        0    0    0    0    0    0    0    0   23    0   50    0
END

COMPND    HMDB0005023
HETATM    1  C1  UNL     1       5.862  -1.105  -0.404  1.00  0.00           C  
HETATM    2  C2  UNL     1       4.394  -1.177  -0.303  1.00  0.00           C  
HETATM    3  C3  UNL     1       3.781  -1.664   0.830  1.00  0.00           C  
HETATM    4  C4  UNL     1       2.410  -1.736   0.936  1.00  0.00           C  
HETATM    5  C5  UNL     1       1.617  -1.304  -0.130  1.00  0.00           C  
HETATM    6  C6  UNL     1       0.182  -1.395  -0.036  1.00  0.00           C  
HETATM    7  N1  UNL     1      -0.445  -2.545   0.357  1.00  0.00           N  
HETATM    8  C7  UNL     1      -1.776  -2.348   0.376  1.00  0.00           C  
HETATM    9  C8  UNL     1      -2.831  -3.185   0.698  1.00  0.00           C  
HETATM   10  C9  UNL     1      -4.107  -2.690   0.621  1.00  0.00           C  
HETATM   11  C10 UNL     1      -4.323  -1.384   0.231  1.00  0.00           C  
HETATM   12  C11 UNL     1      -5.703  -0.815   0.137  1.00  0.00           C  
HETATM   13  C12 UNL     1      -3.229  -0.604  -0.075  1.00  0.00           C  
HETATM   14  N2  UNL     1      -1.969  -1.075  -0.005  1.00  0.00           N  
HETATM   15  C13 UNL     1      -0.798  -0.458  -0.266  1.00  0.00           C  
HETATM   16  C14 UNL     1      -0.623   0.963  -0.701  1.00  0.00           C  
HETATM   17  C15 UNL     1      -0.159   1.796   0.406  1.00  0.00           C  
HETATM   18  O1  UNL     1       0.034   1.283   1.531  1.00  0.00           O  
HETATM   19  N3  UNL     1       0.079   3.183   0.230  1.00  0.00           N  
HETATM   20  C16 UNL     1       0.538   4.011   1.328  1.00  0.00           C  
HETATM   21  C17 UNL     1      -0.124   3.849  -1.049  1.00  0.00           C  
HETATM   22  C18 UNL     1       2.223  -0.821  -1.255  1.00  0.00           C  
HETATM   23  C19 UNL     1       3.615  -0.751  -1.354  1.00  0.00           C  
HETATM   24  H1  UNL     1       6.350  -2.104  -0.383  1.00  0.00           H  
HETATM   25  H2  UNL     1       6.186  -0.579  -1.325  1.00  0.00           H  
HETATM   26  H3  UNL     1       6.267  -0.550   0.487  1.00  0.00           H  
HETATM   27  H4  UNL     1       4.416  -1.993   1.641  1.00  0.00           H  
HETATM   28  H5  UNL     1       1.941  -2.116   1.822  1.00  0.00           H  
HETATM   29  H6  UNL     1      -2.681  -4.197   1.001  1.00  0.00           H  
HETATM   30  H7  UNL     1      -4.986  -3.289   0.859  1.00  0.00           H  
HETATM   31  H8  UNL     1      -6.326  -1.473  -0.503  1.00  0.00           H  
HETATM   32  H9  UNL     1      -6.146  -0.788   1.165  1.00  0.00           H  
HETATM   33  H10 UNL     1      -5.694   0.202  -0.292  1.00  0.00           H  
HETATM   34  H11 UNL     1      -3.383   0.421  -0.382  1.00  0.00           H  
HETATM   35  H12 UNL     1       0.057   1.068  -1.553  1.00  0.00           H  
HETATM   36  H13 UNL     1      -1.656   1.334  -0.960  1.00  0.00           H  
HETATM   37  H14 UNL     1      -0.366   4.475   1.789  1.00  0.00           H  
HETATM   38  H15 UNL     1       1.158   4.834   0.920  1.00  0.00           H  
HETATM   39  H16 UNL     1       1.108   3.412   2.089  1.00  0.00           H  
HETATM   40  H17 UNL     1      -0.868   3.319  -1.674  1.00  0.00           H  
HETATM   41  H18 UNL     1       0.816   3.992  -1.604  1.00  0.00           H  
HETATM   42  H19 UNL     1      -0.576   4.845  -0.823  1.00  0.00           H  
HETATM   43  H20 UNL     1       1.676  -0.482  -2.121  1.00  0.00           H  
HETATM   44  H21 UNL     1       4.056  -0.362  -2.258  1.00  0.00           H  
CONECT    1    2   24   25   26
CONECT    2    3    3   23
CONECT    3    4   27
CONECT    4    5    5   28
CONECT    5    6   22
CONECT    6    7   15   15
CONECT    7    8    8
CONECT    8    9   14
CONECT    9   10   10   29
CONECT   10   11   30
CONECT   11   12   13   13
CONECT   12   31   32   33
CONECT   13   14   34
CONECT   14   15
CONECT   15   16
CONECT   16   17   35   36
CONECT   17   18   18   19
CONECT   19   20   21
CONECT   20   37   38   39
CONECT   21   40   41   42
CONECT   22   23   23   43
CONECT   23   44
END

HMDB0005023
     RDKit          3D
Zolpidem
 44 46  0  0  0  0  0  0  0  0999 V2000
    5.8624   -1.1046   -0.4037 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3945   -1.1767   -0.3026 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7810   -1.6640    0.8299 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4102   -1.7357    0.9361 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6165   -1.3043   -0.1297 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1816   -1.3954   -0.0362 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4450   -2.5451    0.3568 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7756   -2.3477    0.3762 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8306   -3.1851    0.6978 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1073   -2.6902    0.6214 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3232   -1.3836    0.2311 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.7026   -0.8152    0.1368 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2290   -0.6040   -0.0749 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9689   -1.0748   -0.0050 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7979   -0.4580   -0.2660 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6229    0.9632   -0.7007 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1589    1.7958    0.4063 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0343    1.2829    1.5308 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0787    3.1833    0.2304 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.5385    4.0112    1.3285 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1241    3.8494   -1.0495 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2231   -0.8207   -1.2551 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6146   -0.7513   -1.3540 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3501   -2.1040   -0.3826 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.1865   -0.5786   -1.3247 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.2672   -0.5498    0.4873 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.4159   -1.9925    1.6409 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9414   -2.1165    1.8217 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6805   -4.1965    1.0009 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9859   -3.2890    0.8591 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.3259   -1.4729   -0.5031 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1463   -0.7878    1.1650 H   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6935    0.2020   -0.2921 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3831    0.4213   -0.3818 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0568    1.0680   -1.5526 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6556    1.3345   -0.9600 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3663    4.4753    1.7887 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1579    4.8337    0.9196 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1080    3.4119    2.0891 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8681    3.3187   -1.6740 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.8160    3.9924   -1.6036 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5761    4.8452   -0.8231 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.6761   -0.4823   -2.1211 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0561   -0.3624   -2.2581 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  2  0
  3  4  1  0
  4  5  2  0
  5  6  1  0
  6  7  1  0
  7  8  2  0
  8  9  1  0
  9 10  2  0
 10 11  1  0
 11 12  1  0
 11 13  2  0
 13 14  1  0
 14 15  1  0
 15 16  1  0
 16 17  1  0
 17 18  2  0
 17 19  1  0
 19 20  1  0
 19 21  1  0
  5 22  1  0
 22 23  2  0
 23  2  1  0
 15  6  2  0
 14  8  1  0
  1 24  1  0
  1 25  1  0
  1 26  1  0
  3 27  1  0
  4 28  1  0
  9 29  1  0
 10 30  1  0
 12 31  1  0
 12 32  1  0
 12 33  1  0
 13 34  1  0
 16 35  1  0
 16 36  1  0
 20 37  1  0
 20 38  1  0
 20 39  1  0
 21 40  1  0
 21 41  1  0
 21 42  1  0
 22 43  1  0
 23 44  1  0
M  END

View in JSmol View Stereo Labels

Synonyms

Value	Source
N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamide	ChEBI
Zolpidemum	ChEBI
Sanval	Kegg
Ambien	HMDB
Hypnogen	HMDB
Myslee	HMDB
Stilnoct	HMDB
Stilnox	HMDB
Zolpidem ambien	HMDB
Zolpidem tartrate	HMDB
Bikalm	HMDB
Zolpidem 1a pharma	HMDB
N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2a)pyridine-3-acetamide hemitartrate	HMDB
Zolpidem abz	HMDB
Amsic	HMDB
Dalparan	HMDB
Zolpinox	HMDB
Zodormdura	HMDB
Zoldem	HMDB
Zolirin	HMDB
Zolpi-lich	HMDB
Zolpimist	HMDB
Zolpidem hemitartrate	HMDB
Zolpi lich	HMDB

Chemical Formula

C₁₉H₂₁N₃O

Average Molecular Weight

307.3895

Monoisotopic Molecular Weight

307.168462309

IUPAC Name

N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide

Traditional Name

zolpidem

CAS Registry Number

82626-48-0

SMILES

CN(C)C(=O)CC1=C(N=C2C=CC(C)=CN12)C1=CC=C(C)C=C1

InChI Identifier

InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3

InChI Key

ZAFYATHCZYHLPB-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as phenylimidazoles. These are polycyclic aromatic compounds containing a benzene ring linked to an imidazole ring through a CC or CN bond.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Azoles

Sub Class

Imidazoles

Direct Parent

Phenylimidazoles

Alternative Parents

Substituents

5-phenylimidazole
4-phenylimidazole
Imidazopyridine
Imidazo[1,2-a]pyridine
Toluene
Methylpyridine
Monocyclic benzene moiety
N-substituted imidazole
Pyridine
Benzenoid
Tertiary carboxylic acid amide
Heteroaromatic compound
Carboxamide group
Carboxylic acid derivative
Azacycle
Organic oxide
Carbonyl group
Organopnictogen compound
Organic oxygen compound
Organooxygen compound
Organonitrogen compound
Organic nitrogen compound
Hydrocarbon derivative
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

imidazopyridine (CHEBI:10125 )

Ontology

Not Available

Physical Properties

State

Solid

Experimental Molecular Properties

Property	Value	Reference
Melting Point	196 °C	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Experimental Chromatographic Properties

Experimental Collision Cross Sections

Adduct Type	Data Source	CCS Value (Å²)	Reference
[M+H]+	CBM	177.2	30932474

Predicted Molecular Properties

Property	Value	Source
Water Solubility	0.031 g/L	ALOGPS
logP	3.15	ALOGPS
logP	3.02	ChemAxon
logS	-4	ALOGPS
pKa (Strongest Basic)	5.65	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	37.61 Å²	ChemAxon
Rotatable Bond Count	3	ChemAxon
Refractivity	93.58 m³·mol⁻¹	ChemAxon
Polarizability	35.06 Å³	ChemAxon
Number of Rings	3	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	No	ChemAxon

Predicted Chromatographic Properties

Predicted Collision Cross Sections

Predictor	Adduct Type	CCS Value (Å²)	Reference
DarkChem	[M+H]+	174.344	31661259
DarkChem	[M-H]-	175.428	31661259
DeepCCS	[M-2H]-	209.616	30932474
DeepCCS	[M+Na]+	184.843	30932474
AllCCS	[M+H]+	172.9	32859911
AllCCS	[M+H-H2O]+	169.5	32859911
AllCCS	[M+NH4]+	176.1	32859911
AllCCS	[M+Na]+	177.0	32859911
AllCCS	[M-H]-	181.8	32859911
AllCCS	[M+Na-2H]-	181.5	32859911
AllCCS	[M+HCOO]-	181.2	32859911

Predicted Kovats Retention Indices

Underivatized

Metabolite	SMILES	Kovats RI Value	Column Type	Reference
Zolpidem	CN(C)C(=O)CC1=C(N=C2C=CC(C)=CN12)C1=CC=C(C)C=C1	3607.8	Standard polar	33892256
Zolpidem	CN(C)C(=O)CC1=C(N=C2C=CC(C)=CN12)C1=CC=C(C)C=C1	2833.0	Standard non polar	33892256
Zolpidem	CN(C)C(=O)CC1=C(N=C2C=CC(C)=CN12)C1=CC=C(C)C=C1	2797.7	Semi standard non polar	33892256

Spectra

GC-MS Spectra

Spectrum Type	Description	Splash Key	Deposition Date	Source	View
Predicted GC-MS	Predicted GC-MS Spectrum - Zolpidem GC-MS (Non-derivatized) - 70eV, Positive	splash10-007c-4491000000-1f69c88ada0cbe422976	2017-09-01	Wishart Lab	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - Zolpidem GC-MS (Non-derivatized) - 70eV, Positive	Not Available	2021-10-12	Wishart Lab	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - Zolpidem GC-MS (Non-derivatized) - 70eV, Positive	Not Available	2021-10-12	Wishart Lab	View Spectrum
MS	Mass Spectrum (Electron Ionization)	splash10-000i-1090000000-5429f5620534a2340098	2014-09-20	Not Available	View Spectrum

MS/MS Spectra

Spectrum Type	Description	Splash Key	Deposition Date	Source	View
Experimental LC-MS/MS	LC-MS/MS Spectrum - Zolpidem , positive-QTOF	splash10-0a4r-0196000000-6304f5b37ed9f071eb26	2017-09-14	HMDB team, MONA	View Spectrum
Experimental LC-MS/MS	LC-MS/MS Spectrum - Zolpidem 35V, Positive-QTOF	splash10-06ri-0093000000-df20eb1ec18c6314769f	2021-09-20	HMDB team, MONA	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Zolpidem 10V, Positive-QTOF	splash10-0a4i-0049000000-bc33df0258d99c887a5c	2016-08-03	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Zolpidem 20V, Positive-QTOF	splash10-0bti-0095000000-53d24c4b41c278d039e0	2016-08-03	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Zolpidem 40V, Positive-QTOF	splash10-052r-1190000000-fcb2a47c2fab91af9648	2016-08-03	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Zolpidem 10V, Negative-QTOF	splash10-0a4i-0009000000-ad3531d27ad6da8d9cc3	2016-08-03	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Zolpidem 20V, Negative-QTOF	splash10-0bt9-1097000000-084e5a788c15061e05a5	2016-08-03	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Zolpidem 40V, Negative-QTOF	splash10-08fs-2090000000-b2e3eaa1af64958efe10	2016-08-03	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Zolpidem 10V, Negative-QTOF	splash10-0a4i-0009000000-de69c65803e567e26cea	2021-09-22	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Zolpidem 20V, Negative-QTOF	splash10-074i-0093000000-612afe202f557c4a4c66	2021-09-22	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Zolpidem 40V, Negative-QTOF	splash10-0a4i-0490000000-26b5c78b7009ce2e5c1c	2021-09-22	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Zolpidem 10V, Positive-QTOF	splash10-0a4i-0019000000-b660ca11ad7e4f91fd36	2021-09-23	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Zolpidem 20V, Positive-QTOF	splash10-0079-0092000000-37a7218a24afef1be815	2021-09-23	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Zolpidem 40V, Positive-QTOF	splash10-014r-0390000000-fe5078d60002f0380d8e	2021-09-23	Wishart Lab	View Spectrum

Biological Properties

Cellular Locations

Membrane (predicted from logP)

Biospecimen Locations

Blood
Urine

Tissue Locations

Liver

Pathways

Not Available

Name	SMPDB/PathBank	KEGG

Normal Concentrations

Not Available

Abnormal Concentrations

Biospecimen	Status	Value	Age	Sex	Condition	Reference	Details
Blood	Expected but not Quantified	Not Quantified	Not Specified	Not Specified	Cancer patients undergoing total body irradiation	31424920	details
Urine	Detected but not Quantified	Not Quantified	Not Specified	Not Specified	Cancer patients undergoing total body irradiation	31424920	details

Predicted Concentrations

Biospecimen	Value	Original age	Original sex	Original condition	Comments
Blood	0.000 uM	Adult (>18 years old)	Both	Normal	Predicted based on drug qualities
Blood	0.000 umol/mmol creatinine	Adult (>18 years old)	Both	Normal	Predicted based on drug qualities

Associated Disorders and Diseases

Disease References

None

Associated OMIM IDs

None

External Links

DrugBank ID

DB00425

Phenol Explorer Compound ID

Not Available

FooDB ID

FDB023594

KNApSAcK ID

Not Available

Chemspider ID

5530

KEGG Compound ID

C07219

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Zolpidem

METLIN ID

3071

PubChem Compound

5732

PDB ID

Not Available

ChEBI ID

10125

Food Biomarker Ontology

Not Available

VMH ID

Not Available

MarkerDB ID

Not Available

Good Scents ID

Not Available

References

Synthesis Reference

Kaplan, Jean Pierre; George, Pascal. Imidazo[1,2-a]pyridine derivatives and their therapeutic use. Eur. Pat. Appl. (1982), 19 pp. CODEN: EPXXDW EP 50563 A1 19820428 CAN 97:92280 AN 1982:492280

Material Safety Data Sheet (MSDS)

Download (PDF)

General References

Gock SB, Wong SH, Nuwayhid N, Venuti SE, Kelley PD, Teggatz JR, Jentzen JM: Acute zolpidem overdose--report of two cases. J Anal Toxicol. 1999 Oct;23(6):559-62. [PubMed:10517569 ]
Von Moltke LL, Greenblatt DJ, Granda BW, Duan SX, Grassi JM, Venkatakrishnan K, Harmatz JS, Shader RI: Zolpidem metabolism in vitro: responsible cytochromes, chemical inhibitors, and in vivo correlations. Br J Clin Pharmacol. 1999 Jul;48(1):89-97. [PubMed:10383565 ]
von Moltke LL, Weemhoff JL, Perloff MD, Hesse LM, Harmatz JS, Roth-Schechter BF, Greenblatt DJ: Effect of zolpidem on human cytochrome P450 activity, and on transport mediated by P-glycoprotein. Biopharm Drug Dispos. 2002 Dec;23(9):361-7. [PubMed:12469329 ]

Enzymes

Enzyme Details

1. 3'(2'),5'-bisphosphate nucleotidase 1

General function:: Involved in inositol or phosphatidylinositol phosphatase activity
Specific function:: Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Has 1000-fold lower activity towards inositol 1,4-bisphosphate (Ins(1,4)P2) and inositol 1,3,4-trisphosphate (Ins(1,3,4)P3), but does not hydrolyze Ins(1)P, Ins(3,4)P2, Ins(1,3,4,5)P4 or InsP6.
Gene Name:: BPNT1
Uniprot ID:: O95861
Molecular weight:: 33392.035

Enzyme Details

2. Transaldolase

General function:: Involved in catalytic activity
Specific function:: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Gene Name:: TALDO1
Uniprot ID:: P37837
Molecular weight:: 37539.74

Enzyme Details

3. Phosphoserine aminotransferase

General function:: Involved in metabolic process
Specific function:: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine (By similarity).
Gene Name:: PSAT1
Uniprot ID:: Q9Y617
Molecular weight:: 35188.305

Enzyme Details

4. Cytochrome P450 3A4

General function:: Involved in monooxygenase activity
Specific function:: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide.
Gene Name:: CYP3A4
Uniprot ID:: P08684
Molecular weight:: 57255.585

Enzyme Details

5. 14-3-3 protein zeta/delta

General function:: Involved in protein domain specific binding
Specific function:: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner
Gene Name:: YWHAZ
Uniprot ID:: P63104
Molecular weight:: 27744.8

Enzyme Details

6. Translocator protein

General function:: Signal transduction mechanisms
Specific function:: Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells
Gene Name:: TSPO
Uniprot ID:: P30536
Molecular weight:: 18778.7

Enzyme Details

7. Gamma-aminobutyric acid receptor subunit alpha-1

General function:: Involved in ion transport
Specific function:: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:: GABRA1
Uniprot ID:: P14867
Molecular weight:: 51801.4

Enzyme Details

8. 14-3-3 protein beta/alpha

General function:: Involved in protein domain specific binding
Specific function:: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis
Gene Name:: YWHAB
Uniprot ID:: P31946
Molecular weight:: 28082.2

Enzyme Details

9. 14-3-3 protein gamma

General function:: Involved in protein domain specific binding
Specific function:: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner
Gene Name:: YWHAG
Uniprot ID:: P61981
Molecular weight:: 28302.3

Showing metabocard for Zolpidem (HMDB0005023)

MOL for HMDB0005023 (Zolpidem)

3D MOL for HMDB0005023 (Zolpidem)

3D SDF for HMDB0005023 (Zolpidem)

3D-SDF for HMDB0005023 (Zolpidem)

PDB for HMDB0005023 (Zolpidem)

3D PDB for HMDB0005023 (Zolpidem)

SMILES for HMDB0005023 (Zolpidem)

INCHI for HMDB0005023 (Zolpidem)

Structure for HMDB0005023 (Zolpidem)

3D Structure for HMDB0005023 (Zolpidem)

Experimental Collision Cross Sections

Predicted Collision Cross Sections

Predicted Kovats Retention Indices

Underivatized

GC-MS Spectra

MS/MS Spectra

Enzymes