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Record Information
Version5.0
StatusExpected but not Quantified
Creation Date2012-09-06 21:02:41 UTC
Update Date2023-02-21 17:18:35 UTC
HMDB IDHMDB0028837
Secondary Accession Numbers
  • HMDB28837
Metabolite Identification
Common NameGlycyl-Aspartate
DescriptionGlycyl-Aspartate is a dipeptide composed of glycine and aspartate. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. This dipeptide has not yet been identified in human tissues or biofluids and so it is classified as an 'Expected' metabolite.
Structure
Thumb
Synonyms
ValueSource
Glycyl-aspartic acidGenerator
g-D DipeptideHMDB
GD DipeptideHMDB
Gly-aspHMDB
Glycine aspartate dipeptideHMDB
Glycine-aspartate dipeptideHMDB
GlycylaspartateHMDB
L-Glycyl-L-aspartateHMDB
2-[(2-Amino-1-hydroxyethylidene)amino]butanedioateHMDB
Chemical FormulaC6H10N2O5
Average Molecular Weight190.154
Monoisotopic Molecular Weight190.05897144
IUPAC Name2-(2-aminoacetamido)butanedioic acid
Traditional Name2-(2-aminoacetamido)butanedioic acid
CAS Registry NumberNot Available
SMILES
NCC(=O)NC(CC(O)=O)C(O)=O
InChI Identifier
InChI=1S/C6H10N2O5/c7-2-4(9)8-3(6(12)13)1-5(10)11/h3H,1-2,7H2,(H,8,9)(H,10,11)(H,12,13)
InChI KeySCCPDJAQCXWPTF-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.
KingdomOrganic compounds
Super ClassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
Sub ClassAmino acids, peptides, and analogues
Direct ParentDipeptides
Alternative Parents
Substituents
  • Alpha-dipeptide
  • Aspartic acid or derivatives
  • N-acyl-alpha-amino acid
  • N-acyl-alpha amino acid or derivatives
  • Alpha-amino acid amide
  • Alpha-amino acid or derivatives
  • Dicarboxylic acid or derivatives
  • Fatty acid
  • Amino acid or derivatives
  • Carboxamide group
  • Amino acid
  • Secondary carboxylic acid amide
  • Carboxylic acid
  • Organonitrogen compound
  • Organic oxygen compound
  • Organic oxide
  • Primary aliphatic amine
  • Organopnictogen compound
  • Organic nitrogen compound
  • Carbonyl group
  • Organooxygen compound
  • Primary amine
  • Amine
  • Hydrocarbon derivative
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External DescriptorsNot Available
Ontology
Physiological effectNot Available
Disposition
ProcessNot Available
RoleNot Available
Physical Properties
StateSolid
Experimental Molecular Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogP-4.85Extrapolated
Experimental Chromatographic PropertiesNot Available
Predicted Molecular Properties
Predicted Chromatographic Properties
Spectra
Biological Properties
Cellular LocationsNot Available
Biospecimen LocationsNot Available
Tissue LocationsNot Available
Pathways
Normal Concentrations
Not Available
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB111876
KNApSAcK IDNot Available
Chemspider ID240419
KEGG Compound IDNot Available
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkNot Available
METLIN IDNot Available
PubChem Compound273261
PDB IDNot Available
ChEBI IDNot Available
Food Biomarker OntologyNot Available
VMH IDGLYASP
MarkerDB IDNot Available
Good Scents IDNot Available
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Girelli AM, Mattei E, Messina A, Tarola AM: Inhibition of polyphenol oxidases activity by various dipeptides. J Agric Food Chem. 2004 May 19;52(10):2741-5. [PubMed:15137808 ]
  2. O'Brien EC, Farkas E, Rockenbauer A, Nolan KB: Metal complexes of taurine. The first reported solution equilibrium studies for complex formation by taurine at physiological pH; the copper(II)-glycylglycinate-taurine and the copper(II)-glycylaspartate-taurine systems. J Inorg Biochem. 1999 Nov-Dec;77(3-4):135-9. [PubMed:10702036 ]
  3. Huang YB, Xiao YP, Wang H, Hou RZ, Zhang N, Wu XX, Xu L, Zhang XZ: Chemo-enzymatic synthesis of tripeptide RGD diamide in organic solvents. J Biotechnol. 2005 Mar 2;116(1):51-9. Epub 2004 Dec 28. [PubMed:15652429 ]
  4. Feng X, An Y, Yao Z, Li C, Shi G: A turn-on fluorescent sensor for pyrophosphate based on the disassembly of Cu2+-mediated perylene diimide aggregates. ACS Appl Mater Interfaces. 2012 Feb;4(2):614-8. doi: 10.1021/am201616r. Epub 2012 Jan 23. [PubMed:22220681 ]