Record Information |
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Version | 5.0 |
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Status | Detected and Quantified |
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Creation Date | 2005-11-16 15:48:42 UTC |
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Update Date | 2023-05-30 20:55:48 UTC |
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HMDB ID | HMDB0000870 |
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Secondary Accession Numbers | - HMDB0060263
- HMDB00870
- HMDB60263
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Metabolite Identification |
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Common Name | Histamine |
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Description | Histamine is an amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. Histamine can be found in Photobacterium phosphoreum and Lactobacillus (PMID:17066936 ). Histamine belongs to the class of organic compounds known as 2-arylethylamines. These are primary amines that have the general formula RCCNH2, where R is an organic group. High amounts of histamine have been found in spinach, oats and ryes. Another foods such as green beans, broccoli, and beetroots also contain histamine but in lower concentrations. Histamine has also been detected but not quantified in several different foods, such as groundcherries, carobs, bok choy, biscuits, and longans. |
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Structure | InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8) |
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Synonyms | Value | Source |
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1H-Imidazole-4-ethanamine | ChEBI | 2-(4-Imidazolyl)ethylamine | ChEBI | 2-(1H-Imidazol-4-yl)ethanamine | HMDB | 2-(1H-Imidazol-4-yl)ethylamine | HMDB | 2-(1H-Imidazol-5-yl)ethanamine | HMDB | 2-(1H-Imidazol-5-yl)ethylamine | HMDB | 2-(4-Imidazolyl)ethanamine | HMDB | 2-Imidazol-4-yl-ethylamine | HMDB | 2-Imidazol-4-ylethylamine | HMDB | 4-(2-Aminoethyl)-1H-imidazole | HMDB | 4-(2-Aminoethyl)imidazole | HMDB | 4-Imidazoleethylamine | HMDB | 5-Imidazoleethylamine | HMDB | b-Imidazolyl-4-ethylamine | HMDB | beta-Aminoethylglyoxaline | HMDB | beta-Aminoethylimidazole | HMDB | beta-Aminothethylglyoxaline | HMDB | beta-Imidazolyl-4-ethylamine | HMDB | Eramin | HMDB | Ergamine | HMDB | Ergotidine | HMDB | HSM | HMDB | 2-(3H-Imidazol-4-yl)ethylamine | HMDB | Imidazole-4-ethylamine | HMDB | Β-imidazolyl-4-ethylamine | HMDB | Histamine | HMDB |
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Chemical Formula | C5H9N3 |
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Average Molecular Weight | 111.1451 |
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Monoisotopic Molecular Weight | 111.079647303 |
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IUPAC Name | 2-(1H-imidazol-4-yl)ethan-1-amine |
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Traditional Name | histamine |
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CAS Registry Number | 51-45-6 |
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SMILES | NCCC1=CNC=N1 |
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InChI Identifier | InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8) |
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InChI Key | NTYJJOPFIAHURM-UHFFFAOYSA-N |
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Chemical Taxonomy |
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Description | Belongs to the class of organic compounds known as 2-arylethylamines. These are primary amines that have the general formula RCCNH2, where R is an organic group. |
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Kingdom | Organic compounds |
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Super Class | Organic nitrogen compounds |
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Class | Organonitrogen compounds |
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Sub Class | Amines |
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Direct Parent | 2-arylethylamines |
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Alternative Parents | |
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Substituents | - 2-arylethylamine
- Aralkylamine
- Heteroaromatic compound
- Imidazole
- Azole
- Azacycle
- Organoheterocyclic compound
- Organopnictogen compound
- Hydrocarbon derivative
- Primary aliphatic amine
- Aromatic heteromonocyclic compound
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Molecular Framework | Aromatic heteromonocyclic compounds |
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External Descriptors | |
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Ontology |
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Physiological effect | Not Available |
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Disposition | |
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Process | |
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Role | |
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Physical Properties |
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State | Solid |
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Experimental Molecular Properties | |
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Experimental Chromatographic Properties | Experimental Collision Cross Sections |
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Predicted Molecular Properties | |
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Predicted Chromatographic Properties | Predicted Collision Cross SectionsPredicted Kovats Retention IndicesUnderivatizedDerivatizedDerivative Name / Structure | SMILES | Kovats RI Value | Column Type | Reference |
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Histamine,1TMS,isomer #1 | C[Si](C)(C)NCCC1=C[NH]C=N1 | 1441.7 | Semi standard non polar | 33892256 | Histamine,1TMS,isomer #1 | C[Si](C)(C)NCCC1=C[NH]C=N1 | 1555.9 | Standard non polar | 33892256 | Histamine,1TMS,isomer #1 | C[Si](C)(C)NCCC1=C[NH]C=N1 | 1941.3 | Standard polar | 33892256 | Histamine,1TMS,isomer #2 | C[Si](C)(C)N1C=NC(CCN)=C1 | 1511.1 | Semi standard non polar | 33892256 | Histamine,1TMS,isomer #2 | C[Si](C)(C)N1C=NC(CCN)=C1 | 1439.5 | Standard non polar | 33892256 | Histamine,1TMS,isomer #2 | C[Si](C)(C)N1C=NC(CCN)=C1 | 2073.4 | Standard polar | 33892256 | Histamine,2TMS,isomer #1 | C[Si](C)(C)N(CCC1=C[NH]C=N1)[Si](C)(C)C | 1669.5 | Semi standard non polar | 33892256 | Histamine,2TMS,isomer #1 | C[Si](C)(C)N(CCC1=C[NH]C=N1)[Si](C)(C)C | 1749.3 | Standard non polar | 33892256 | Histamine,2TMS,isomer #1 | C[Si](C)(C)N(CCC1=C[NH]C=N1)[Si](C)(C)C | 1911.5 | Standard polar | 33892256 | Histamine,2TMS,isomer #2 | C[Si](C)(C)NCCC1=CN([Si](C)(C)C)C=N1 | 1645.4 | Semi standard non polar | 33892256 | Histamine,2TMS,isomer #2 | C[Si](C)(C)NCCC1=CN([Si](C)(C)C)C=N1 | 1608.4 | Standard non polar | 33892256 | Histamine,2TMS,isomer #2 | C[Si](C)(C)NCCC1=CN([Si](C)(C)C)C=N1 | 1851.5 | Standard polar | 33892256 | Histamine,3TMS,isomer #1 | C[Si](C)(C)N(CCC1=CN([Si](C)(C)C)C=N1)[Si](C)(C)C | 1862.3 | Semi standard non polar | 33892256 | Histamine,3TMS,isomer #1 | C[Si](C)(C)N(CCC1=CN([Si](C)(C)C)C=N1)[Si](C)(C)C | 1829.9 | Standard non polar | 33892256 | Histamine,3TMS,isomer #1 | C[Si](C)(C)N(CCC1=CN([Si](C)(C)C)C=N1)[Si](C)(C)C | 1837.4 | Standard polar | 33892256 | Histamine,1TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)NCCC1=C[NH]C=N1 | 1657.1 | Semi standard non polar | 33892256 | Histamine,1TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)NCCC1=C[NH]C=N1 | 1817.6 | Standard non polar | 33892256 | Histamine,1TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)NCCC1=C[NH]C=N1 | 2076.3 | Standard polar | 33892256 | Histamine,1TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)N1C=NC(CCN)=C1 | 1752.4 | Semi standard non polar | 33892256 | Histamine,1TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)N1C=NC(CCN)=C1 | 1623.5 | Standard non polar | 33892256 | Histamine,1TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)N1C=NC(CCN)=C1 | 2181.3 | Standard polar | 33892256 | Histamine,2TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)N(CCC1=C[NH]C=N1)[Si](C)(C)C(C)(C)C | 2037.1 | Semi standard non polar | 33892256 | Histamine,2TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)N(CCC1=C[NH]C=N1)[Si](C)(C)C(C)(C)C | 2206.2 | Standard non polar | 33892256 | Histamine,2TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)N(CCC1=C[NH]C=N1)[Si](C)(C)C(C)(C)C | 2077.9 | Standard polar | 33892256 | Histamine,2TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)NCCC1=CN([Si](C)(C)C(C)(C)C)C=N1 | 2108.3 | Semi standard non polar | 33892256 | Histamine,2TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)NCCC1=CN([Si](C)(C)C(C)(C)C)C=N1 | 2008.8 | Standard non polar | 33892256 | Histamine,2TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)NCCC1=CN([Si](C)(C)C(C)(C)C)C=N1 | 2027.1 | Standard polar | 33892256 | Histamine,3TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)N(CCC1=CN([Si](C)(C)C(C)(C)C)C=N1)[Si](C)(C)C(C)(C)C | 2466.2 | Semi standard non polar | 33892256 | Histamine,3TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)N(CCC1=CN([Si](C)(C)C(C)(C)C)C=N1)[Si](C)(C)C(C)(C)C | 2399.8 | Standard non polar | 33892256 | Histamine,3TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)N(CCC1=CN([Si](C)(C)C(C)(C)C)C=N1)[Si](C)(C)C(C)(C)C | 2128.2 | Standard polar | 33892256 |
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| GC-MS SpectraSpectrum Type | Description | Splash Key | Deposition Date | Source | View |
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Experimental GC-MS | GC-MS Spectrum - Histamine GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS) | splash10-0f79-5910000000-9946e1707fcaf5562f88 | 2014-06-16 | HMDB team, MONA, MassBank | View Spectrum | Experimental GC-MS | GC-MS Spectrum - Histamine GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (Non-derivatized) | splash10-00di-2910000000-8c243055df15d6ce8116 | 2014-06-16 | HMDB team, MONA, MassBank | View Spectrum | Experimental GC-MS | GC-MS Spectrum - Histamine GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS) | splash10-00di-9710000000-bf79b524c104e1cc94ba | 2014-06-16 | HMDB team, MONA, MassBank | View Spectrum | Experimental GC-MS | GC-MS Spectrum - Histamine GC-MS (2 TMS) | splash10-0udi-2900000000-a40a3d0aed04ccfe9365 | 2014-06-16 | HMDB team, MONA, MassBank | View Spectrum | Experimental GC-MS | GC-MS Spectrum - Histamine GC-MS (3 TMS) | splash10-00dr-3910000000-44d8fb649d4e75eba66c | 2014-06-16 | HMDB team, MONA, MassBank | View Spectrum | Experimental GC-MS | GC-MS Spectrum - Histamine GC-EI-TOF (Non-derivatized) | splash10-0f79-5910000000-9946e1707fcaf5562f88 | 2017-09-12 | HMDB team, MONA, MassBank | View Spectrum | Experimental GC-MS | GC-MS Spectrum - Histamine GC-EI-TOF (Non-derivatized) | splash10-00di-2910000000-8c243055df15d6ce8116 | 2017-09-12 | HMDB team, MONA, MassBank | View Spectrum | Experimental GC-MS | GC-MS Spectrum - Histamine GC-EI-TOF (Non-derivatized) | splash10-00di-9710000000-bf79b524c104e1cc94ba | 2017-09-12 | HMDB team, MONA, MassBank | View Spectrum | Experimental GC-MS | GC-MS Spectrum - Histamine GC-MS (Non-derivatized) | splash10-0udi-2900000000-a40a3d0aed04ccfe9365 | 2017-09-12 | HMDB team, MONA, MassBank | View Spectrum | Experimental GC-MS | GC-MS Spectrum - Histamine GC-MS (Non-derivatized) | splash10-00dr-3910000000-44d8fb649d4e75eba66c | 2017-09-12 | HMDB team, MONA, MassBank | View Spectrum | Experimental GC-MS | GC-MS Spectrum - Histamine GC-MS (Non-derivatized) | splash10-0udi-2900000000-a40a3d0aed04ccfe9365 | 2017-09-12 | HMDB team, MONA, MassBank | View Spectrum | Experimental GC-MS | GC-MS Spectrum - Histamine GC-MS (Non-derivatized) | splash10-00dr-3910000000-44d8fb649d4e75eba66c | 2017-09-12 | HMDB team, MONA, MassBank | View Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - Histamine GC-MS (Non-derivatized) - 70eV, Positive | splash10-001i-9100000000-3de6a14d8a45af6c9d66 | 2016-09-22 | Wishart Lab | View Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - Histamine GC-MS (Non-derivatized) - 70eV, Positive | Not Available | 2021-10-12 | Wishart Lab | View Spectrum | MS | Mass Spectrum (Electron Ionization) | splash10-001i-9000000000-9d57c893be8c75ce8178 | 2014-09-20 | Not Available | View Spectrum |
MS/MS SpectraSpectrum Type | Description | Splash Key | Deposition Date | Source | View |
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Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine Quattro_QQQ 10V, Positive-QTOF (Annotated) | splash10-01ot-9600000000-06c58d75770dfd76aeab | 2012-07-24 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine Quattro_QQQ 25V, Positive-QTOF (Annotated) | splash10-00kf-9000000000-0135b8f0628e592abc22 | 2012-07-24 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine Quattro_QQQ 40V, Positive-QTOF (Annotated) | splash10-000x-9000000000-6fccc177582b320a48ae | 2012-07-24 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positive-QTOF | splash10-03di-1900000000-6cda8885da689473fb42 | 2012-08-31 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positive-QTOF | splash10-0002-9100000000-37450d9969c24ad44ad7 | 2012-08-31 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine LC-ESI-QQ (API3000, Applied Biosystems) 30V, Positive-QTOF | splash10-0002-9000000000-e9e368926d3146437e13 | 2012-08-31 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine LC-ESI-QQ (API3000, Applied Biosystems) 40V, Positive-QTOF | splash10-015a-9000000000-f51ad8a8259595600938 | 2012-08-31 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine LC-ESI-QQ (API3000, Applied Biosystems) 50V, Positive-QTOF | splash10-00lu-9000000000-3e02d5b58a7c9f77ec53 | 2012-08-31 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Positive-QTOF | splash10-03di-0900000000-046407320168835599f0 | 2012-08-31 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine , negative-QTOF | splash10-03di-3900000000-29ccabc0b6f5396168f2 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine LC-ESI-QQ , positive-QTOF | splash10-03di-1900000000-6cda8885da689473fb42 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine LC-ESI-QQ , positive-QTOF | splash10-0002-9100000000-37450d9969c24ad44ad7 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine LC-ESI-QQ , positive-QTOF | splash10-0002-9000000000-e9e368926d3146437e13 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine LC-ESI-QQ , positive-QTOF | splash10-015a-9000000000-f51ad8a8259595600938 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine LC-ESI-QQ , positive-QTOF | splash10-00lu-9000000000-77394d92ed9170d75b98 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine LC-ESI-QTOF , positive-QTOF | splash10-03di-0900000000-046407320168835599f0 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine , positive-QTOF | splash10-01ot-9400000000-a19fc5e555afd53dafe7 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine 20V, Positive-QTOF | splash10-0002-9000000000-982b635075f56f26d216 | 2021-09-20 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Histamine 40V, Positive-QTOF | splash10-0frx-9000000000-262a5d1ecfe104fb5771 | 2021-09-20 | HMDB team, MONA | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Histamine 10V, Positive-QTOF | splash10-03dj-9700000000-b06ddb1eb7ed3ddf4f69 | 2015-04-24 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Histamine 20V, Positive-QTOF | splash10-0002-9200000000-a93565f24c40eddb6cf4 | 2015-04-24 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Histamine 40V, Positive-QTOF | splash10-0uxr-9000000000-71d70766bb4f9d3b13a0 | 2015-04-24 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Histamine 10V, Negative-QTOF | splash10-03di-2900000000-2705dc2d177edbc4faa4 | 2015-04-25 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Histamine 20V, Negative-QTOF | splash10-03di-6900000000-9e9ebaae6f68b4c2d89d | 2015-04-25 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Histamine 40V, Negative-QTOF | splash10-00kf-9000000000-9d4fe74f18b21423615d | 2015-04-25 | Wishart Lab | View Spectrum |
NMR SpectraSpectrum Type | Description | Deposition Date | Source | View |
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Experimental 1D NMR | 1H NMR Spectrum (1D, 500 MHz, H2O, experimental) | 2012-12-04 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 100 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 100 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 1000 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 1000 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 200 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 200 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 300 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 300 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 400 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 400 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 500 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 500 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 600 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 600 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 700 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 700 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 800 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 1H NMR Spectrum (1D, 800 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Predicted 1D NMR | 13C NMR Spectrum (1D, 900 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | Experimental 2D NMR | [1H, 13C]-HSQC NMR Spectrum (2D, 600 MHz, H2O, experimental) | 2012-12-05 | Wishart Lab | View Spectrum |
IR SpectraSpectrum Type | Description | Deposition Date | Source | View |
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Predicted IR Spectrum | IR Ion Spectrum (Predicted IRIS Spectrum, Adduct: [M-H]-) | 2023-02-03 | FELIX lab | View Spectrum | Predicted IR Spectrum | IR Ion Spectrum (Predicted IRIS Spectrum, Adduct: [M+H]+) | 2023-02-03 | FELIX lab | View Spectrum | Predicted IR Spectrum | IR Ion Spectrum (Predicted IRIS Spectrum, Adduct: [M+Na]+) | 2023-02-03 | FELIX lab | View Spectrum |
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Disease References | Nephrotic syndrome |
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- Gill DS, Fonseca VA, Barradas MA, Balliod R, Moorhead JF, Dandona P: Plasma histamine in patients with chronic renal failure and nephrotic syndrome. J Clin Pathol. 1991 Mar;44(3):243-5. [PubMed:2013627 ]
| Hemodialysis |
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- Gill DS, Fonseca VA, Barradas MA, Balliod R, Moorhead JF, Dandona P: Plasma histamine in patients with chronic renal failure and nephrotic syndrome. J Clin Pathol. 1991 Mar;44(3):243-5. [PubMed:2013627 ]
| Kidney disease |
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- Gill DS, Fonseca VA, Barradas MA, Balliod R, Moorhead JF, Dandona P: Plasma histamine in patients with chronic renal failure and nephrotic syndrome. J Clin Pathol. 1991 Mar;44(3):243-5. [PubMed:2013627 ]
| Continuous ambulatory peritoneal dialysis |
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- Gill DS, Fonseca VA, Barradas MA, Balliod R, Moorhead JF, Dandona P: Plasma histamine in patients with chronic renal failure and nephrotic syndrome. J Clin Pathol. 1991 Mar;44(3):243-5. [PubMed:2013627 ]
| Colorectal cancer |
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- Brown DG, Rao S, Weir TL, O'Malia J, Bazan M, Brown RJ, Ryan EP: Metabolomics and metabolic pathway networks from human colorectal cancers, adjacent mucosa, and stool. Cancer Metab. 2016 Jun 6;4:11. doi: 10.1186/s40170-016-0151-y. eCollection 2016. [PubMed:27275383 ]
- Sinha R, Ahn J, Sampson JN, Shi J, Yu G, Xiong X, Hayes RB, Goedert JJ: Fecal Microbiota, Fecal Metabolome, and Colorectal Cancer Interrelations. PLoS One. 2016 Mar 25;11(3):e0152126. doi: 10.1371/journal.pone.0152126. eCollection 2016. [PubMed:27015276 ]
- Goedert JJ, Sampson JN, Moore SC, Xiao Q, Xiong X, Hayes RB, Ahn J, Shi J, Sinha R: Fecal metabolomics: assay performance and association with colorectal cancer. Carcinogenesis. 2014 Sep;35(9):2089-96. doi: 10.1093/carcin/bgu131. Epub 2014 Jul 18. [PubMed:25037050 ]
| Eosinophilic esophagitis |
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- Slae, M., Huynh, H., Wishart, D.S. (2014). Analysis of 30 normal pediatric urine samples via NMR spectroscopy (unpublished work). NA.
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General References | - Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, Yu J, Laxman B, Mehra R, Lonigro RJ, Li Y, Nyati MK, Ahsan A, Kalyana-Sundaram S, Han B, Cao X, Byun J, Omenn GS, Ghosh D, Pennathur S, Alexander DC, Berger A, Shuster JR, Wei JT, Varambally S, Beecher C, Chinnaiyan AM: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4. doi: 10.1038/nature07762. [PubMed:19212411 ]
- Dvorak AM: New aspects of mast cell biology. Int Arch Allergy Immunol. 1997 Sep;114(1):1-9. [PubMed:9303324 ]
- Ito C: The role of the central histaminergic system on schizophrenia. Drug News Perspect. 2004 Jul-Aug;17(6):383-7. [PubMed:15334189 ]
- Bordignon V, Burastero SE: Age, gender and reactivity to allergens independently influence skin reactivity to histamine. J Investig Allergol Clin Immunol. 2006;16(2):129-35. [PubMed:16689187 ]
- Yosipovitch G, Fast K, Bernhard JD: Noxious heat and scratching decrease histamine-induced itch and skin blood flow. J Invest Dermatol. 2005 Dec;125(6):1268-72. [PubMed:16354198 ]
- Koizumi H, Ohkawara A: H2 histamine receptor-mediated increase in intracellular Ca2+ in cultured human keratinocytes. J Dermatol Sci. 1999 Sep;21(2):127-32. [PubMed:10511481 ]
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