- Metabolite
- HMDB0002658 (6-Hydroxynicotinic acid)
- Biospecimen
- Urine
- Status
- Detected but not Quantified
- Data source
- Referenced
- Concentration
- Not Quantified
- Age
- Adult (>18 years old)
- Sex
- Both
- Condition
- Diabetes mellitus
Comments
With the consumption of cocoa powder and chocolate (solid). Participants have diabetes mellitus or more than three cardiovascular risk factors: tobacco smoking, hypertension, LDL cholesterol ≥ 160 mg/dL, HDL cholesterol ≤ 35 mg/dL,overweight or obesity (BMI ≥ 25 kg/m2), and/or family history of premature coronary heart disease. Exclusion criteria included documented coronary heart disease, stroke or peripheral arteriopathy, as well as a history of allergic reactionsto any cocoa components
References
- Llorach R, Urpi-Sarda M, Tulipani S, Garcia-Aloy M, Monagas M, Andres-Lacueva C: Metabolomic fingerprint in patients at high risk of cardiovascular disease by cocoa intervention. Mol Nutr Food Res. 2013 Jun;57(6):962-73. doi: 10.1002/mnfr.201200736. Epub 2013 May 2. [PubMed:23637065 ]