HMDB0000045 (Adenosine monophosphate) HMDB0000250 (Pyrophosphate) HMDB0000538 (Adenosine triphosphate) HMDB0015182 (Abacavir) HMDB0061723 (Carbovir Triphosphate)
- HMDB0000250 (Pyrophosphate)
- Abacavir Action Pathway
- intracellularly, abacavir is converted by cellular enzymes to the active metabolite carbovir triphosphate, an analogue of deoxyguanosine-5'-triphosphate (dgtp). carbovir triphosphate inhibits the activity of hiv-1 reverse transcriptase (rt) both by competing with the natural substrate dgtp and by its incorporation into viral dna.
- Parent Term
- Biochemical pathway
- Parent Definition
- A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
- Other Metabolites Mapped to 'Abacavir Action Pathway'