inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (fpp and ggpp) that are essential for the post-translational farnesylation and geranylgeranylation of small gtpase signalling proteins. this activity inhibits osteoclast activity and reduces bone resorption and turnover.
Parent Term
Biochemical pathway
Parent Definition
A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
Other Metabolites Mapped to 'Alendronate Action Pathway'