Ontological Term Details

Metabolite
HMDB0005998 (20-Hydroxyeicosatetraenoic acid)
Term
Celecoxib Action Pathway
Definition
like other nsaids, celecoxib exerts its effects by inhibiting the synthesis of prostaglandins involved in pain, fever and inflammation. cox-2 catalyzes the conversion of arachidonic acid to prostaglandin g2 (pge2) and pge2 to prostaglandin h2 (pgh2).
Parent Term
Biochemical pathway
Parent Definition
A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
Other Metabolites Mapped to 'Celecoxib Action Pathway'
  • HMDB0000125 (Glutathione)
  • HMDB0000148 (L-Glutamic acid)
  • HMDB0000217 (NADP)
  • HMDB0000221 (NADPH)
  • HMDB0000295 (Uridine 5'-diphosphate)
  • HMDB0000464 (Calcium)
  • HMDB0000547 (Magnesium)
  • HMDB0000935 (Uridine diphosphate glucuronic acid)
  • HMDB0001043 (Arachidonic acid)
  • HMDB0001085 (Leukotriene B4)
  • References

        Not Available