HMDB0000217 (NADP) HMDB0000221 (NADPH) HMDB0001377 (Oxygen) HMDB0002111 (Water) HMDB0003178 (Heme) HMDB0015282 (Desipramine) HMDB0059597 (Hydrogen Ion) HMDB0060716 (2-Hydroxy-desipramine glucuronide) HMDB0060992 (2-hydroxydesipramine)
- HMDB0003178 (Heme)
- Desipramine Metabolism Pathway
- it does so by competing for the same binding site as norepinephrine on the sodium-dependent noradraneline transporter (slc6a2) and by competing with serotonin for binding to the sodium-dependent serotonin transporter (slc6a4). this increases the concentrations of both norepinephrine and serotonin in their respective synapses and reverses the state of low concentrations of both neurotransmitters found in depression.
- Parent Term
- Biochemical pathway
- Parent Definition
- A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
- Other Metabolites Mapped to 'Desipramine Metabolism Pathway'