Ontological Term Details

Metabolite
HMDB0005998 (20-Hydroxyeicosatetraenoic acid)
Term
Etoricoxib Action Pathway
Definition
the mechanism of action of etoricoxib is thought to be due to its ability to block prostaglandin synthesis by inhibiting cyclooxygenase 2 (cox-2), also called prostaglandin g/h synthase 2. cox-2 catalyze the conversion of arachidonic acid to prostaglandin g2 and prostaglandin g2 to prostglandin h2.
Parent Term
Biochemical pathway
Parent Definition
A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
Other Metabolites Mapped to 'Etoricoxib Action Pathway'
  • HMDB0000125 (Glutathione)
  • HMDB0000148 (L-Glutamic acid)
  • HMDB0000217 (NADP)
  • HMDB0000221 (NADPH)
  • HMDB0000464 (Calcium)
  • HMDB0000547 (Magnesium)
  • HMDB0001043 (Arachidonic acid)
  • HMDB0001085 (Leukotriene B4)
  • HMDB0001139 (Prostaglandin F2a)
  • HMDB0001198 (Leukotriene C4)
  • References

        Not Available