the first two are synthesized from acetyl-coa, in the mitochondria of liver cells; acetone is formed by spontaneous decarboxylation of acetoacetate. ketone body synthesis (ketogenesis) in liver is effectively irreversible because the enzyme that catalyzes the conversion of acetoacetate to acetoacetyl-coa is not present in liver cells.
Parent Term
Biochemical pathway
Parent Definition
A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
Other Metabolites Mapped to 'Ketone Body Metabolism'