Metabolite: HMDB0001337 (Leukotriene A4)
Term: Rofecoxib Action Pathway
Definition: like other nsaids, rofecoxib exerts its effects by inhibiting the synthesis of prostaglandins involved in pain, fever and inflammation. cox-2 catalyzes the conversion of arachidonic acid to prostaglandin g2 (pgg2) and pgg2 to prostaglandin h2 (pgh2).
Parent Term: Biochemical pathway
Parent Definition: A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
Other Metabolites Mapped to 'Rofecoxib Action Pathway'