HMDB0000538 (Adenosine triphosphate) HMDB0000547 (Magnesium) HMDB0001341 (ADP) HMDB0014445 (Tenofovir) HMDB0061280 (Tenofovir Monophosphate) HMDB0061281 (Tenofovir Diphosphate)
- HMDB0014445 (Tenofovir)
- Tenofovir Metabolism Pathway
- it is taken up into the cell and is subsequently phosphorylated first by adenylate kinases and then by nucleoside diphosphate kinases into tenofovir diphosphate. tenofovir diphosphate is an analogue of deoxyadenosine triphosphate (datp) and competes with datp for binding to the viral dna polymerase and subsequent incorporation into the growing dna strand.
- Parent Term
- Biochemical pathway
- Parent Definition
- A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
- Other Metabolites Mapped to 'Tenofovir Metabolism Pathway'