Ontological Term Details

Metabolite
HMDB0000797 (SAICAR)
Term
Thioguanine Action Pathway
Definition
the thioguanine pathway is shown as a part of the mercaptopurine pathway. thioguanine exerts cytotoxic effects via incorporation of thiodeoxyguanosine triphosphate into dna and thioguanosine triphosphate into rna and inhibition of ras-related c3 botulinum toxin substrate 1, which induces apoptosis of activated t cells.
Parent Term
Biochemical pathway
Parent Definition
A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
Other Metabolites Mapped to 'Thioguanine Action Pathway'
  • HMDB0000034 (Adenine)
  • HMDB0000045 (Adenosine monophosphate)
  • HMDB0000050 (Adenosine)
  • HMDB0000051 (Ammonia)
  • HMDB0000058 (Cyclic AMP)
  • HMDB0000071 (Deoxyinosine)
  • HMDB0000085 (Deoxyguanosine)
  • HMDB0000101 (Deoxyadenosine)
  • HMDB0000123 (Glycine)
  • HMDB0000132 (Guanine)
  • References

        Not Available