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Record Information
Version5.0
StatusDetected but not Quantified
Creation Date2012-09-11 17:43:54 UTC
Update Date2022-03-07 02:53:01 UTC
HMDB IDHMDB0031531
Secondary Accession Numbers
  • HMDB31531
Metabolite Identification
Common NameDihydro-5-pentyl-2(3H)-furanone
DescriptionDihydro-5-pentyl-2(3H)-furanone, also known as g-nonanolide, belongs to the class of organic compounds known as gamma butyrolactones. Gamma butyrolactones are compounds containing a gamma butyrolactone moiety, which consists of an aliphatic five-member ring with four carbon atoms, one oxygen atom, and bears a ketone group on the carbon adjacent to the oxygen atom. Thus, dihydro-5-pentyl-2(3H)-furanone is considered to be a fatty ester. Based on a literature review very few articles have been published on Dihydro-5-pentyl-2(3H)-furanone.
Structure
Data?1563862137
Synonyms
ValueSource
g-NonanolideHMDB
Γ-nonanolideHMDB
Chemical FormulaC9H16O2
Average Molecular Weight156.2221
Monoisotopic Molecular Weight156.115029756
IUPAC Name5-pentyloxolan-2-one
Traditional Name5-pentyloxolan-2-one
CAS Registry Number57084-16-9
SMILES
CCCCCC1CCC(=O)O1
InChI Identifier
InChI=1S/C9H16O2/c1-2-3-4-5-8-6-7-9(10)11-8/h8H,2-7H2,1H3
InChI KeyOALYTRUKMRCXNH-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as gamma butyrolactones. Gamma butyrolactones are compounds containing a gamma butyrolactone moiety, which consists of an aliphatic five-member ring with four carbon atoms, one oxygen atom, and bears a ketone group on the carbon adjacent to the oxygen atom.
KingdomOrganic compounds
Super ClassOrganoheterocyclic compounds
ClassLactones
Sub ClassGamma butyrolactones
Direct ParentGamma butyrolactones
Alternative Parents
Substituents
  • Gamma butyrolactone
  • Tetrahydrofuran
  • Carboxylic acid ester
  • Oxacycle
  • Monocarboxylic acid or derivatives
  • Carboxylic acid derivative
  • Organic oxygen compound
  • Organic oxide
  • Hydrocarbon derivative
  • Organooxygen compound
  • Carbonyl group
  • Aliphatic heteromonocyclic compound
Molecular FrameworkAliphatic heteromonocyclic compounds
External Descriptors
Ontology
Disposition

Biological location

Physical Properties
StateNot Available
Experimental Molecular Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Experimental Chromatographic PropertiesNot Available
Predicted Molecular Properties
PropertyValueSource
Water Solubility0.58 g/LALOGPS
logP2.41ALOGPS
logP2.42ChemAxon
logS-2.4ALOGPS
pKa (Strongest Basic)-7ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area26.3 ŲChemAxon
Rotatable Bond Count4ChemAxon
Refractivity43.05 m³·mol⁻¹ChemAxon
Polarizability18.33 ųChemAxon
Number of Rings1ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted Chromatographic Properties

Predicted Collision Cross Sections

PredictorAdduct TypeCCS Value (Å2)Reference
DarkChem[M+H]+137.16431661259
DarkChem[M-H]-132.84831661259
DeepCCS[M+H]+140.14730932474
DeepCCS[M-H]-137.1930932474
DeepCCS[M-2H]-174.32930932474
DeepCCS[M+Na]+149.27730932474

Predicted Kovats Retention Indices

Underivatized

MetaboliteSMILESKovats RI ValueColumn TypeReference
Dihydro-5-pentyl-2(3H)-furanoneCCCCCC1CCC(=O)O12050.2Standard polar33892256
Dihydro-5-pentyl-2(3H)-furanoneCCCCCC1CCC(=O)O11293.0Standard non polar33892256
Dihydro-5-pentyl-2(3H)-furanoneCCCCCC1CCC(=O)O11383.1Semi standard non polar33892256
Spectra

GC-MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Experimental GC-MSGC-MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone EI-B (Non-derivatized)splash10-000i-9000000000-b49a9ba5068e6a6f37e22017-09-12HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone EI-B (Non-derivatized)splash10-000i-9000000000-b49a9ba5068e6a6f37e22018-05-18HMDB team, MONA, MassBankView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone GC-MS (Non-derivatized) - 70eV, Positivesplash10-0a6r-9100000000-af0a79e6fed6da9b90e52016-09-22Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone GC-MS (Non-derivatized) - 70eV, PositiveNot Available2021-10-12Wishart LabView Spectrum

MS/MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone 10V, Positive-QTOFsplash10-0a4i-3900000000-744435374457def1ad432016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone 20V, Positive-QTOFsplash10-0a4j-9400000000-138d9d1b3adff2cc8bc22016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone 40V, Positive-QTOFsplash10-052f-9000000000-2aef2660fd27b623a33a2016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone 10V, Negative-QTOFsplash10-0a4i-0900000000-8a84aa8e2a9449a5fa562016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone 20V, Negative-QTOFsplash10-0bt9-2900000000-f3ab54e2cccc6f3c6d412016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone 40V, Negative-QTOFsplash10-0006-9200000000-582e8883da5af41a1b0e2016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone 10V, Positive-QTOFsplash10-0596-9200000000-f9386d8ee820b5a6d62d2021-09-22Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone 20V, Positive-QTOFsplash10-052f-9100000000-db15bac3d76d44b010872021-09-22Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone 40V, Positive-QTOFsplash10-0006-9000000000-fb82163f045c302c5a5a2021-09-22Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone 10V, Negative-QTOFsplash10-0a4i-0900000000-376389ca50b091133eac2021-09-22Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone 20V, Negative-QTOFsplash10-0a4i-1900000000-046e7beacadfb7f2d9db2021-09-22Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Dihydro-5-pentyl-2(3H)-furanone 40V, Negative-QTOFsplash10-0006-9200000000-4575218cc7d74da5620e2021-09-22Wishart LabView Spectrum
Biological Properties
Cellular Locations
  • Cytoplasm
  • Extracellular
Biospecimen Locations
  • Saliva
Tissue LocationsNot Available
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
SalivaDetected but not QuantifiedNot QuantifiedAdult (>18 years old)BothNormal details
SalivaDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Not SpecifiedNormal details
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB008138
KNApSAcK IDC00001318
Chemspider ID7424
KEGG Compound IDNot Available
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkNot Available
METLIN IDNot Available
PubChem Compound7710
PDB IDNot Available
ChEBI IDNot Available
Food Biomarker OntologyNot Available
VMH IDNot Available
MarkerDB IDNot Available
Good Scents IDNot Available
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General References
  1. (). Yannai, Shmuel. (2004) Dictionary of food compounds with CD-ROM: Additives, flavors, and ingredients. Boca Raton: Chapman & Hall/CRC.. .