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Record Information

Version

5.0

Status

Expected but not Quantified

Creation Date

2012-09-12 01:51:19 UTC

Update Date

2022-03-07 02:56:33 UTC

HMDB ID

HMDB0040322

Secondary Accession Numbers

HMDB40322

Metabolite Identification

Common Name

3'-Hydroxy-4',5',7,8-tetramethoxyflavone

Description

3'-Hydroxy-4',5',7,8-tetramethoxyflavone belongs to the class of organic compounds known as 8-o-methylated flavonoids. These are flavonoids with methoxy groups attached to the C8 atom of the flavonoid backbone. Thus, 3'-hydroxy-4',5',7,8-tetramethoxyflavone is considered to be a flavonoid. 3'-Hydroxy-4',5',7,8-tetramethoxyflavone has been detected, but not quantified in, fruits. This could make 3'-hydroxy-4',5',7,8-tetramethoxyflavone a potential biomarker for the consumption of these foods. Based on a literature review very few articles have been published on 3'-Hydroxy-4',5',7,8-tetramethoxyflavone.

Structure

MOL 3D MOL SDF 3D SDF PDB 3D PDB SMILES InChI


  Mrv0541 05061311452D          

 26 28  0  0  0  0            999 V2000
    0.0000    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  6  5  2  0  0  0  0
 10  7  2  0  0  0  0
 10  8  1  0  0  0  0
 11  5  1  0  0  0  0
 12  9  1  0  0  0  0
 12 11  1  0  0  0  0
 13  7  1  0  0  0  0
 14  6  1  0  0  0  0
 15  9  2  0  0  0  0
 15 10  1  0  0  0  0
 16  8  2  0  0  0  0
 17 11  2  0  0  0  0
 18 13  2  0  0  0  0
 18 16  1  0  0  0  0
 19 14  2  0  0  0  0
 19 17  1  0  0  0  0
 20 12  2  0  0  0  0
 21 13  1  0  0  0  0
 22  1  1  0  0  0  0
 22 14  1  0  0  0  0
 23  2  1  0  0  0  0
 23 16  1  0  0  0  0
 24  3  1  0  0  0  0
 24 18  1  0  0  0  0
 25  4  1  0  0  0  0
 25 19  1  0  0  0  0
 26 15  1  0  0  0  0
 26 17  1  0  0  0  0
M  END

HMDB0040322
     RDKit          3D
3'-Hydroxy-4',5',7,8-tetramethoxyflavone
 44 46  0  0  0  0  0  0  0  0999 V2000
   -2.9775   -2.9890   -0.6371 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7856   -1.8801   -0.3432 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3355   -0.6075   -0.0542 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0008   -0.2718   -0.0200 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5598    1.0182    0.2730 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1446    1.3371    0.3036 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3888    2.5724    0.5683 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7418    2.8206    0.5847 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2510    3.9407    0.8237 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6027    1.7715    0.3214 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9705    1.9360    0.3188 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7724    0.8560    0.0505 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2446   -0.3925   -0.2170 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0914   -1.4590   -0.4832 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.4810   -1.3510   -0.4989 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8736   -0.5196   -0.2060 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3448   -1.7588   -0.4715 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.0758   -2.7283    0.5223 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0232    0.5413    0.0594 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7221    0.3626    0.0570 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5114    1.9715    0.5334 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8727    1.6316    0.4991 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8462    2.5846    0.7601 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3067    0.3584    0.2100 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6491    0.0416    0.1809 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4954    0.1160   -0.9215 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8959   -3.5969    0.3108 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9876   -2.7494   -1.0374 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5734   -3.6388   -1.3378 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2538   -1.0336   -0.2277 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2893    3.3974    0.7754 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.4136    2.8872    0.5220 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.8663    0.9839    0.0473 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.9220   -2.2386   -1.0316 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.9305   -1.3605    0.5260 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.8496   -0.4544   -1.0290 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1700   -2.4300    1.0722 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9380   -2.8425    1.2081 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.8963   -3.7093    0.0370 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2410    3.0046    0.7712 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5363    3.5222    0.9724 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4359    1.0761   -1.4767 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.3136   -0.7644   -1.5680 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.5579    0.0443   -0.5749 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  2  0
  4  5  1  0
  5  6  1  0
  6  7  2  0
  7  8  1  0
  8  9  2  0
  8 10  1  0
 10 11  2  0
 11 12  1  0
 12 13  2  0
 13 14  1  0
 14 15  1  0
 13 16  1  0
 16 17  1  0
 17 18  1  0
 16 19  2  0
 19 20  1  0
  5 21  2  0
 21 22  1  0
 22 23  1  0
 22 24  2  0
 24 25  1  0
 25 26  1  0
 24  3  1  0
 20  6  1  0
 19 10  1  0
  1 27  1  0
  1 28  1  0
  1 29  1  0
  4 30  1  0
  7 31  1  0
 11 32  1  0
 12 33  1  0
 15 34  1  0
 15 35  1  0
 15 36  1  0
 18 37  1  0
 18 38  1  0
 18 39  1  0
 21 40  1  0
 23 41  1  0
 26 42  1  0
 26 43  1  0
 26 44  1  0
M  END


  Mrv0541 05061311452D          

 26 28  0  0  0  0            999 V2000
    0.0000    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.8592   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0013   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.4302   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724    2.0625    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.7158   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.1447   -1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  6  5  2  0  0  0  0
 10  7  2  0  0  0  0
 10  8  1  0  0  0  0
 11  5  1  0  0  0  0
 12  9  1  0  0  0  0
 12 11  1  0  0  0  0
 13  7  1  0  0  0  0
 14  6  1  0  0  0  0
 15  9  2  0  0  0  0
 15 10  1  0  0  0  0
 16  8  2  0  0  0  0
 17 11  2  0  0  0  0
 18 13  2  0  0  0  0
 18 16  1  0  0  0  0
 19 14  2  0  0  0  0
 19 17  1  0  0  0  0
 20 12  2  0  0  0  0
 21 13  1  0  0  0  0
 22  1  1  0  0  0  0
 22 14  1  0  0  0  0
 23  2  1  0  0  0  0
 23 16  1  0  0  0  0
 24  3  1  0  0  0  0
 24 18  1  0  0  0  0
 25  4  1  0  0  0  0
 25 19  1  0  0  0  0
 26 15  1  0  0  0  0
 26 17  1  0  0  0  0
M  END
> <DATABASE_ID>
HMDB0040322

> <DATABASE_NAME>
hmdb

> <SMILES>
COC1=CC(=CC(O)=C1OC)C1=CC(=O)C2=C(O1)C(OC)=C(OC)C=C2

> <INCHI_IDENTIFIER>
InChI=1S/C19H18O7/c1-22-14-6-5-11-12(20)9-15(26-17(11)19(14)25-4)10-7-13(21)18(24-3)16(8-10)23-2/h5-9,21H,1-4H3

> <INCHI_KEY>
LCFAQXHDTREUOX-UHFFFAOYSA-N

> <FORMULA>
C19H18O7

> <MOLECULAR_WEIGHT>
358.342

> <EXACT_MASS>
358.10525293

> <JCHEM_ACCEPTOR_COUNT>
7

> <JCHEM_AVERAGE_POLARIZABILITY>
36.67159650148757

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
2-(3-hydroxy-4,5-dimethoxyphenyl)-7,8-dimethoxy-4H-chromen-4-one

> <ALOGPS_LOGP>
2.96

> <JCHEM_LOGP>
2.0331347143333334

> <ALOGPS_LOGS>
-4.10

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
3

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
15.852991299152045

> <JCHEM_PKA_STRONGEST_ACIDIC>
9.585227450812724

> <JCHEM_PKA_STRONGEST_BASIC>
-4.304793458128112

> <JCHEM_POLAR_SURFACE_AREA>
83.45000000000002

> <JCHEM_REFRACTIVITY>
94.80489999999998

> <JCHEM_ROTATABLE_BOND_COUNT>
5

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
2.84e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
2-(3-hydroxy-4,5-dimethoxyphenyl)-7,8-dimethoxychromen-4-one

> <JCHEM_VEBER_RULE>
0

$$$$

HMDB0040322
     RDKit          3D
3'-Hydroxy-4',5',7,8-tetramethoxyflavone
 44 46  0  0  0  0  0  0  0  0999 V2000
   -2.9775   -2.9890   -0.6371 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7856   -1.8801   -0.3432 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3355   -0.6075   -0.0542 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0008   -0.2718   -0.0200 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5598    1.0182    0.2730 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1446    1.3371    0.3036 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3888    2.5724    0.5683 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7418    2.8206    0.5847 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2510    3.9407    0.8237 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6027    1.7715    0.3214 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9705    1.9360    0.3188 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7724    0.8560    0.0505 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2446   -0.3925   -0.2170 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0914   -1.4590   -0.4832 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.4810   -1.3510   -0.4989 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8736   -0.5196   -0.2060 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3448   -1.7588   -0.4715 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.0758   -2.7283    0.5223 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0232    0.5413    0.0594 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7221    0.3626    0.0570 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5114    1.9715    0.5334 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8727    1.6316    0.4991 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8462    2.5846    0.7601 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3067    0.3584    0.2100 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6491    0.0416    0.1809 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4954    0.1160   -0.9215 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8959   -3.5969    0.3108 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9876   -2.7494   -1.0374 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5734   -3.6388   -1.3378 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2538   -1.0336   -0.2277 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2893    3.3974    0.7754 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.4136    2.8872    0.5220 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.8663    0.9839    0.0473 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.9220   -2.2386   -1.0316 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.9305   -1.3605    0.5260 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.8496   -0.4544   -1.0290 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1700   -2.4300    1.0722 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9380   -2.8425    1.2081 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.8963   -3.7093    0.0370 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2410    3.0046    0.7712 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5363    3.5222    0.9724 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4359    1.0761   -1.4767 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.3136   -0.7644   -1.5680 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.5579    0.0443   -0.5749 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  2  0
  4  5  1  0
  5  6  1  0
  6  7  2  0
  7  8  1  0
  8  9  2  0
  8 10  1  0
 10 11  2  0
 11 12  1  0
 12 13  2  0
 13 14  1  0
 14 15  1  0
 13 16  1  0
 16 17  1  0
 17 18  1  0
 16 19  2  0
 19 20  1  0
  5 21  2  0
 21 22  1  0
 22 23  1  0
 22 24  2  0
 24 25  1  0
 25 26  1  0
 24  3  1  0
 20  6  1  0
 19 10  1  0
  1 27  1  0
  1 28  1  0
  1 29  1  0
  4 30  1  0
  7 31  1  0
 11 32  1  0
 12 33  1  0
 15 34  1  0
 15 35  1  0
 15 36  1  0
 18 37  1  0
 18 38  1  0
 18 39  1  0
 21 40  1  0
 23 41  1  0
 26 42  1  0
 26 43  1  0
 26 44  1  0
M  END

HEADER    PROTEIN                                 06-MAY-13   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   06-MAY-13         0                                  
HETATM    1  C   UNK     0       0.000   0.000   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      12.003  -5.390   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      14.671  -2.310   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0       5.335  -3.080   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0       4.001   2.310   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0       2.667   1.540   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      10.669   0.000   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       9.336  -2.310   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       8.002   1.540   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       9.336  -0.770   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       5.335   1.540   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       6.668   2.310   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      12.003  -0.770   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0       2.667   0.000   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0       8.002   0.000   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      10.669  -3.080   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0       5.335   0.000   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      12.003  -2.310   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0       4.001  -0.770   0.000  0.00  0.00           C+0
HETATM   20  O   UNK     0       6.668   3.850   0.000  0.00  0.00           O+0
HETATM   21  O   UNK     0      13.337   0.000   0.000  0.00  0.00           O+0
HETATM   22  O   UNK     0       1.334  -0.770   0.000  0.00  0.00           O+0
HETATM   23  O   UNK     0      10.669  -4.620   0.000  0.00  0.00           O+0
HETATM   24  O   UNK     0      13.337  -3.080   0.000  0.00  0.00           O+0
HETATM   25  O   UNK     0       4.001  -2.310   0.000  0.00  0.00           O+0
HETATM   26  O   UNK     0       6.668  -0.770   0.000  0.00  0.00           O+0
CONECT    1   22                                                            
CONECT    2   23                                                            
CONECT    3   24                                                            
CONECT    4   25                                                            
CONECT    5    6   11                                                       
CONECT    6    5   14                                                       
CONECT    7   10   13                                                       
CONECT    8   10   16                                                       
CONECT    9   12   15                                                       
CONECT   10    7    8   15                                                  
CONECT   11    5   12   17                                                  
CONECT   12    9   11   20                                                  
CONECT   13    7   18   21                                                  
CONECT   14    6   19   22                                                  
CONECT   15    9   10   26                                                  
CONECT   16    8   18   23                                                  
CONECT   17   11   19   26                                                  
CONECT   18   13   16   24                                                  
CONECT   19   14   17   25                                                  
CONECT   20   12                                                            
CONECT   21   13                                                            
CONECT   22    1   14                                                       
CONECT   23    2   16                                                       
CONECT   24    3   18                                                       
CONECT   25    4   19                                                       
CONECT   26   15   17                                                       
MASTER        0    0    0    0    0    0    0    0   26    0   56    0
END

COMPND    HMDB0040322
HETATM    1  C1  UNL     1      -2.978  -2.989  -0.637  1.00  0.00           C  
HETATM    2  O1  UNL     1      -3.786  -1.880  -0.343  1.00  0.00           O  
HETATM    3  C2  UNL     1      -3.336  -0.607  -0.054  1.00  0.00           C  
HETATM    4  C3  UNL     1      -2.001  -0.272  -0.020  1.00  0.00           C  
HETATM    5  C4  UNL     1      -1.560   1.018   0.273  1.00  0.00           C  
HETATM    6  C5  UNL     1      -0.145   1.337   0.304  1.00  0.00           C  
HETATM    7  C6  UNL     1       0.389   2.572   0.568  1.00  0.00           C  
HETATM    8  C7  UNL     1       1.742   2.821   0.585  1.00  0.00           C  
HETATM    9  O2  UNL     1       2.251   3.941   0.824  1.00  0.00           O  
HETATM   10  C8  UNL     1       2.603   1.771   0.321  1.00  0.00           C  
HETATM   11  C9  UNL     1       3.971   1.936   0.319  1.00  0.00           C  
HETATM   12  C10 UNL     1       4.772   0.856   0.051  1.00  0.00           C  
HETATM   13  C11 UNL     1       4.245  -0.392  -0.217  1.00  0.00           C  
HETATM   14  O3  UNL     1       5.091  -1.459  -0.483  1.00  0.00           O  
HETATM   15  C12 UNL     1       6.481  -1.351  -0.499  1.00  0.00           C  
HETATM   16  C13 UNL     1       2.874  -0.520  -0.206  1.00  0.00           C  
HETATM   17  O4  UNL     1       2.345  -1.759  -0.472  1.00  0.00           O  
HETATM   18  C14 UNL     1       2.076  -2.728   0.522  1.00  0.00           C  
HETATM   19  C15 UNL     1       2.023   0.541   0.059  1.00  0.00           C  
HETATM   20  O5  UNL     1       0.722   0.363   0.057  1.00  0.00           O  
HETATM   21  C16 UNL     1      -2.511   1.971   0.533  1.00  0.00           C  
HETATM   22  C17 UNL     1      -3.873   1.632   0.499  1.00  0.00           C  
HETATM   23  O6  UNL     1      -4.846   2.585   0.760  1.00  0.00           O  
HETATM   24  C18 UNL     1      -4.307   0.358   0.210  1.00  0.00           C  
HETATM   25  O7  UNL     1      -5.649   0.042   0.181  1.00  0.00           O  
HETATM   26  C19 UNL     1      -6.495   0.116  -0.921  1.00  0.00           C  
HETATM   27  H1  UNL     1      -2.896  -3.597   0.311  1.00  0.00           H  
HETATM   28  H2  UNL     1      -1.988  -2.749  -1.037  1.00  0.00           H  
HETATM   29  H3  UNL     1      -3.573  -3.639  -1.338  1.00  0.00           H  
HETATM   30  H4  UNL     1      -1.254  -1.034  -0.228  1.00  0.00           H  
HETATM   31  H5  UNL     1      -0.289   3.397   0.775  1.00  0.00           H  
HETATM   32  H6  UNL     1       4.414   2.887   0.522  1.00  0.00           H  
HETATM   33  H7  UNL     1       5.866   0.984   0.047  1.00  0.00           H  
HETATM   34  H8  UNL     1       6.922  -2.239  -1.032  1.00  0.00           H  
HETATM   35  H9  UNL     1       6.931  -1.360   0.526  1.00  0.00           H  
HETATM   36  H10 UNL     1       6.850  -0.454  -1.029  1.00  0.00           H  
HETATM   37  H11 UNL     1       1.170  -2.430   1.072  1.00  0.00           H  
HETATM   38  H12 UNL     1       2.938  -2.843   1.208  1.00  0.00           H  
HETATM   39  H13 UNL     1       1.896  -3.709   0.037  1.00  0.00           H  
HETATM   40  H14 UNL     1      -2.241   3.005   0.771  1.00  0.00           H  
HETATM   41  H15 UNL     1      -4.536   3.522   0.972  1.00  0.00           H  
HETATM   42  H16 UNL     1      -6.436   1.076  -1.477  1.00  0.00           H  
HETATM   43  H17 UNL     1      -6.314  -0.764  -1.568  1.00  0.00           H  
HETATM   44  H18 UNL     1      -7.558   0.044  -0.575  1.00  0.00           H  
CONECT    1    2   27   28   29
CONECT    2    3
CONECT    3    4    4   24
CONECT    4    5   30
CONECT    5    6   21   21
CONECT    6    7    7   20
CONECT    7    8   31
CONECT    8    9    9   10
CONECT   10   11   11   19
CONECT   11   12   32
CONECT   12   13   13   33
CONECT   13   14   16
CONECT   14   15
CONECT   15   34   35   36
CONECT   16   17   19   19
CONECT   17   18
CONECT   18   37   38   39
CONECT   19   20
CONECT   21   22   40
CONECT   22   23   24   24
CONECT   23   41
CONECT   24   25
CONECT   25   26
CONECT   26   42   43   44
END

HMDB0040322
     RDKit          3D
3'-Hydroxy-4',5',7,8-tetramethoxyflavone
 44 46  0  0  0  0  0  0  0  0999 V2000
   -2.9775   -2.9890   -0.6371 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7856   -1.8801   -0.3432 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3355   -0.6075   -0.0542 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0008   -0.2718   -0.0200 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5598    1.0182    0.2730 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1446    1.3371    0.3036 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3888    2.5724    0.5683 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7418    2.8206    0.5847 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2510    3.9407    0.8237 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6027    1.7715    0.3214 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9705    1.9360    0.3188 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7724    0.8560    0.0505 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2446   -0.3925   -0.2170 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.0914   -1.4590   -0.4832 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.4810   -1.3510   -0.4989 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8736   -0.5196   -0.2060 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3448   -1.7588   -0.4715 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.0758   -2.7283    0.5223 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0232    0.5413    0.0594 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7221    0.3626    0.0570 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5114    1.9715    0.5334 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8727    1.6316    0.4991 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8462    2.5846    0.7601 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3067    0.3584    0.2100 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6491    0.0416    0.1809 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4954    0.1160   -0.9215 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8959   -3.5969    0.3108 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9876   -2.7494   -1.0374 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5734   -3.6388   -1.3378 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2538   -1.0336   -0.2277 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2893    3.3974    0.7754 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.4136    2.8872    0.5220 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.8663    0.9839    0.0473 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.9220   -2.2386   -1.0316 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.9305   -1.3605    0.5260 H   0  0  0  0  0  0  0  0  0  0  0  0
    6.8496   -0.4544   -1.0290 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.1700   -2.4300    1.0722 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9380   -2.8425    1.2081 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.8963   -3.7093    0.0370 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2410    3.0046    0.7712 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5363    3.5222    0.9724 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4359    1.0761   -1.4767 H   0  0  0  0  0  0  0  0  0  0  0  0
   -6.3136   -0.7644   -1.5680 H   0  0  0  0  0  0  0  0  0  0  0  0
   -7.5579    0.0443   -0.5749 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  2  0
  4  5  1  0
  5  6  1  0
  6  7  2  0
  7  8  1  0
  8  9  2  0
  8 10  1  0
 10 11  2  0
 11 12  1  0
 12 13  2  0
 13 14  1  0
 14 15  1  0
 13 16  1  0
 16 17  1  0
 17 18  1  0
 16 19  2  0
 19 20  1  0
  5 21  2  0
 21 22  1  0
 22 23  1  0
 22 24  2  0
 24 25  1  0
 25 26  1  0
 24  3  1  0
 20  6  1  0
 19 10  1  0
  1 27  1  0
  1 28  1  0
  1 29  1  0
  4 30  1  0
  7 31  1  0
 11 32  1  0
 12 33  1  0
 15 34  1  0
 15 35  1  0
 15 36  1  0
 18 37  1  0
 18 38  1  0
 18 39  1  0
 21 40  1  0
 23 41  1  0
 26 42  1  0
 26 43  1  0
 26 44  1  0
M  END

View in JSmol View Stereo Labels

Synonyms

Value	Source
3'-Hydroxy-7,8,4',5'-tetramethoxyflavone	HMDB

Chemical Formula

C₁₉H₁₈O₇

Average Molecular Weight

358.342

Monoisotopic Molecular Weight

358.10525293

IUPAC Name

2-(3-hydroxy-4,5-dimethoxyphenyl)-7,8-dimethoxy-4H-chromen-4-one

Traditional Name

2-(3-hydroxy-4,5-dimethoxyphenyl)-7,8-dimethoxychromen-4-one

CAS Registry Number

133342-98-0

SMILES

COC1=CC(=CC(O)=C1OC)C1=CC(=O)C2=C(O1)C(OC)=C(OC)C=C2

InChI Identifier

InChI=1S/C19H18O7/c1-22-14-6-5-11-12(20)9-15(26-17(11)19(14)25-4)10-7-13(21)18(24-3)16(8-10)23-2/h5-9,21H,1-4H3

InChI Key

LCFAQXHDTREUOX-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as 8-o-methylated flavonoids. These are flavonoids with methoxy groups attached to the C8 atom of the flavonoid backbone.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Flavonoids

Sub Class

O-methylated flavonoids

Direct Parent

8-O-methylated flavonoids

Alternative Parents

Substituents

3p-methoxyflavonoid-skeleton
4p-methoxyflavonoid-skeleton
7-methoxyflavonoid-skeleton
8-methoxyflavonoid-skeleton
3'-hydroxyflavonoid
Flavone
Hydroxyflavonoid
Monohydroxyflavonoid
Chromone
Benzopyran
O-dimethoxybenzene
Dimethoxybenzene
Methoxyphenol
1-benzopyran
Phenoxy compound
Anisole
Methoxybenzene
Phenol ether
Pyranone
1-hydroxy-2-unsubstituted benzenoid
Phenol
Alkyl aryl ether
1-hydroxy-4-unsubstituted benzenoid
Pyran
Benzenoid
Monocyclic benzene moiety
Heteroaromatic compound
Organoheterocyclic compound
Oxacycle
Ether
Organic oxide
Organic oxygen compound
Organooxygen compound
Hydrocarbon derivative
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Flavones and Flavonols (LMPK12110077 )

Ontology

Physiological effect

Not Available

Disposition

Biological location

Cellular substructure

Membrane (HMDB: HMDB0040322)
Cell membrane (HMDB: HMDB0040322)

Route of exposure

Enteral

Ingestion (HMDB: HMDB0040322)

Source

Exogenous

Exogenous (HMDB: HMDB0040322)

Food

Food (HMDB: HMDB0040322)

Fruit

Fruits (FooDB: FOOD00871)

Endogenous

Plant

Plant (HMDB: HMDB0040322)

Process

Not Available

Role

Biological role

Nutrient (HMDB: HMDB0040322)

Physical Properties

State

Solid

Experimental Molecular Properties

Property	Value	Reference
Melting Point	212 - 213 °C	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	34.62 mg/L @ 25 °C (est)	The Good Scents Company Information System
LogP	Not Available	Not Available

Experimental Chromatographic Properties

Not Available

Predicted Molecular Properties

Property	Value	Source
Water Solubility	0.028 g/L	ALOGPS
logP	2.96	ALOGPS
logP	2.03	ChemAxon
logS	-4.1	ALOGPS
pKa (Strongest Acidic)	9.59	ChemAxon
pKa (Strongest Basic)	-4.3	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	7	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	83.45 Å²	ChemAxon
Rotatable Bond Count	5	ChemAxon
Refractivity	94.8 m³·mol⁻¹	ChemAxon
Polarizability	36.67 Å³	ChemAxon
Number of Rings	3	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Predicted Chromatographic Properties

Predicted Collision Cross Sections

Predictor	Adduct Type	CCS Value (Å²)	Reference
DarkChem	[M+H]+	184.975	31661259
DarkChem	[M-H]-	184.995	31661259
DeepCCS	[M+H]+	183.884	30932474
DeepCCS	[M-H]-	181.526	30932474
DeepCCS	[M-2H]-	215.769	30932474
DeepCCS	[M+Na]+	190.997	30932474
AllCCS	[M+H]+	183.4	32859911
AllCCS	[M+H-H2O]+	180.2	32859911
AllCCS	[M+NH4]+	186.4	32859911
AllCCS	[M+Na]+	187.3	32859911
AllCCS	[M-H]-	186.4	32859911
AllCCS	[M+Na-2H]-	186.1	32859911
AllCCS	[M+HCOO]-	185.9	32859911

Predicted Retention Times

Underivatized

Chromatographic Method	Retention Time	Reference
Measured using a Waters Acquity ultraperformance liquid chromatography (UPLC) ethylene-bridged hybrid (BEH) C18 column (100 mm × 2.1 mm; 1.7 μmparticle diameter). Predicted by Afia on May 17, 2022.	6.74 minutes	32390414
Predicted by Siyang on May 30, 2022	11.9634 minutes	33406817
Predicted by Siyang using ReTip algorithm on June 8, 2022	1.1 minutes	32390414
Fem_Long = Waters ACQUITY UPLC HSS T3 C18 with Water:MeOH and 0.1% Formic Acid	2162.8 seconds	40023050
Fem_Lipids = Ascentis Express C18 with (60:40 water:ACN):(90:10 IPA:ACN) and 10mM NH4COOH + 0.1% Formic Acid	233.9 seconds	40023050
Life_Old = Waters ACQUITY UPLC BEH C18 with Water:(20:80 acetone:ACN) and 0.1% Formic Acid	170.0 seconds	40023050
Life_New = RP Waters ACQUITY UPLC HSS T3 C18 with Water:(30:70 MeOH:ACN) and 0.1% Formic Acid	176.4 seconds	40023050
RIKEN = Waters ACQUITY UPLC BEH C18 with Water:ACN and 0.1% Formic Acid	145.5 seconds	40023050
Eawag_XBridgeC18 = XBridge C18 3.5u 2.1x50 mm with Water:MeOH and 0.1% Formic Acid	498.2 seconds	40023050
BfG_NTS_RP1 =Agilent Zorbax Eclipse Plus C18 (2.1 mm x 150 mm, 3.5 um) with Water:ACN and 0.1% Formic Acid	497.5 seconds	40023050
HILIC_BDD_2 = Merck SeQuant ZIC-HILIC with ACN(0.1% formic acid):water(16 mM ammonium formate)	192.7 seconds	40023050
UniToyama_Atlantis = RP Waters Atlantis T3 (2.1 x 150 mm, 5 um) with ACN:Water and 0.1% Formic Acid	933.9 seconds	40023050
BDD_C18 = Hypersil Gold 1.9µm C18 with Water:ACN and 0.1% Formic Acid	425.8 seconds	40023050
UFZ_Phenomenex = Kinetex Core-Shell C18 2.6 um, 3.0 x 100 mm, Phenomenex with Water:MeOH and 0.1% Formic Acid	1308.2 seconds	40023050
SNU_RIKEN_POS = Waters ACQUITY UPLC BEH C18 with Water:ACN and 0.1% Formic Acid	354.4 seconds	40023050
RPMMFDA = Waters ACQUITY UPLC BEH C18 with Water:ACN and 0.1% Formic Acid	360.4 seconds	40023050
MTBLS87 = Merck SeQuant ZIC-pHILIC column with ACN:Water and :ammonium carbonate	323.1 seconds	40023050
KI_GIAR_zic_HILIC_pH2_7 = Merck SeQuant ZIC-HILIC with ACN:Water and 0.1% FA	327.2 seconds	40023050
Meister zic-pHILIC pH9.3 = Merck SeQuant ZIC-pHILIC column with ACN:Water 5mM NH4Ac pH9.3 and 5mM ammonium acetate in water	36.0 seconds	40023050

Predicted Kovats Retention Indices

Underivatized

Metabolite	SMILES	Kovats RI Value	Column Type	Reference
3'-Hydroxy-4',5',7,8-tetramethoxyflavone	COC1=CC(=CC(O)=C1OC)C1=CC(=O)C2=C(O1)C(OC)=C(OC)C=C2	4809.0	Standard polar	33892256
3'-Hydroxy-4',5',7,8-tetramethoxyflavone	COC1=CC(=CC(O)=C1OC)C1=CC(=O)C2=C(O1)C(OC)=C(OC)C=C2	3244.6	Standard non polar	33892256
3'-Hydroxy-4',5',7,8-tetramethoxyflavone	COC1=CC(=CC(O)=C1OC)C1=CC(=O)C2=C(O1)C(OC)=C(OC)C=C2	3261.8	Semi standard non polar	33892256

Derivatized

Derivative Name / Structure	SMILES	Kovats RI Value	Column Type	Reference
3'-Hydroxy-4',5',7,8-tetramethoxyflavone,1TMS,isomer #1	COC1=CC(C2=CC(=O)C3=CC=C(OC)C(OC)=C3O2)=CC(O[Si](C)(C)C)=C1OC	3235.0	Semi standard non polar	33892256
3'-Hydroxy-4',5',7,8-tetramethoxyflavone,1TBDMS,isomer #1	COC1=CC(C2=CC(=O)C3=CC=C(OC)C(OC)=C3O2)=CC(O[Si](C)(C)C(C)(C)C)=C1OC	3463.8	Semi standard non polar	33892256

Spectra

GC-MS Spectra

Spectrum Type	Description	Splash Key	Deposition Date	Source	View
Predicted GC-MS	Predicted GC-MS Spectrum - 3'-Hydroxy-4',5',7,8-tetramethoxyflavone GC-MS (Non-derivatized) - 70eV, Positive	splash10-004l-0219000000-f7e368071f74bcf6975e	2017-09-01	Wishart Lab	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - 3'-Hydroxy-4',5',7,8-tetramethoxyflavone GC-MS (1 TMS) - 70eV, Positive	splash10-01b9-2118900000-4088443b6474ade67975	2017-10-06	Wishart Lab	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - 3'-Hydroxy-4',5',7,8-tetramethoxyflavone GC-MS (Non-derivatized) - 70eV, Positive	Not Available	2021-10-12	Wishart Lab	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - 3'-Hydroxy-4',5',7,8-tetramethoxyflavone GC-MS (Non-derivatized) - 70eV, Positive	Not Available	2021-10-12	Wishart Lab	View Spectrum

MS/MS Spectra

Spectrum Type	Description	Splash Key	Deposition Date	Source	View
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 3'-Hydroxy-4',5',7,8-tetramethoxyflavone 10V, Positive-QTOF	splash10-0a4i-0009000000-88e1e94a054e8130cd6b	2017-09-01	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 3'-Hydroxy-4',5',7,8-tetramethoxyflavone 20V, Positive-QTOF	splash10-0a4i-1019000000-8d9f36c8abd20c8ea41c	2017-09-01	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 3'-Hydroxy-4',5',7,8-tetramethoxyflavone 40V, Positive-QTOF	splash10-0pbi-0952000000-f8b5822f4fbd8c62a43c	2017-09-01	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 3'-Hydroxy-4',5',7,8-tetramethoxyflavone 10V, Negative-QTOF	splash10-0a4i-0009000000-b17e8da6c759db3099d8	2017-09-01	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 3'-Hydroxy-4',5',7,8-tetramethoxyflavone 20V, Negative-QTOF	splash10-0a4i-0009000000-fa34ff5afe6da3a5bd04	2017-09-01	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 3'-Hydroxy-4',5',7,8-tetramethoxyflavone 40V, Negative-QTOF	splash10-056r-0191000000-f7700c72373a6d31d1f1	2017-09-01	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 3'-Hydroxy-4',5',7,8-tetramethoxyflavone 10V, Positive-QTOF	splash10-0a4i-0009000000-9216d00d19e0b6ee7720	2021-09-23	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 3'-Hydroxy-4',5',7,8-tetramethoxyflavone 20V, Positive-QTOF	splash10-0a4i-0009000000-e8d30684b099443b2b9d	2021-09-23	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 3'-Hydroxy-4',5',7,8-tetramethoxyflavone 40V, Positive-QTOF	splash10-014u-0369000000-512e36030e750eb8ffa7	2021-09-23	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 3'-Hydroxy-4',5',7,8-tetramethoxyflavone 10V, Negative-QTOF	splash10-0a4i-0009000000-c2a6e417d0c66429ddb2	2021-09-24	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 3'-Hydroxy-4',5',7,8-tetramethoxyflavone 20V, Negative-QTOF	splash10-0btc-0009000000-16edd4fbb0bb96b9c50e	2021-09-24	Wishart Lab	View Spectrum

Biological Properties

Cellular Locations

Membrane

Biospecimen Locations

Not Available

Tissue Locations

Not Available

Pathways

Not Available

Name	SMPDB/PathBank	KEGG

Normal Concentrations

Not Available

Abnormal Concentrations

Not Available

Associated Disorders and Diseases

Disease References

None

Associated OMIM IDs

None

External Links

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

FDB020045

KNApSAcK ID

C00004078

Chemspider ID

23339931

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

44257591

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

VMH ID

Not Available

MarkerDB ID

Not Available

Good Scents ID

rw1882661

References

Synthesis Reference

Not Available

Material Safety Data Sheet (MSDS)

Not Available

General References

(). Yannai, Shmuel. (2004) Dictionary of food compounds with CD-ROM: Additives, flavors, and ingredients. Boca Raton: Chapman & Hall/CRC.. .

Showing metabocard for 3'-Hydroxy-4',5',7,8-tetramethoxyflavone (HMDB0040322)

MOL for HMDB0040322 (3'-Hydroxy-4',5',7,8-tetramethoxyflavone)

3D MOL for HMDB0040322 (3'-Hydroxy-4',5',7,8-tetramethoxyflavone)

3D SDF for HMDB0040322 (3'-Hydroxy-4',5',7,8-tetramethoxyflavone)

3D-SDF for HMDB0040322 (3'-Hydroxy-4',5',7,8-tetramethoxyflavone)

PDB for HMDB0040322 (3'-Hydroxy-4',5',7,8-tetramethoxyflavone)

3D PDB for HMDB0040322 (3'-Hydroxy-4',5',7,8-tetramethoxyflavone)

SMILES for HMDB0040322 (3'-Hydroxy-4',5',7,8-tetramethoxyflavone)

INCHI for HMDB0040322 (3'-Hydroxy-4',5',7,8-tetramethoxyflavone)

Structure for HMDB0040322 (3'-Hydroxy-4',5',7,8-tetramethoxyflavone)

3D Structure for HMDB0040322 (3'-Hydroxy-4',5',7,8-tetramethoxyflavone)

Predicted Collision Cross Sections

Predicted Retention Times

Underivatized

Predicted Kovats Retention Indices

Underivatized

Derivatized

GC-MS Spectra

MS/MS Spectra