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Record Information
Version5.0
StatusDetected but not Quantified
Creation Date2021-09-11 00:00:16 UTC
Update Date2021-09-26 22:56:24 UTC
HMDB IDHMDB0246984
Secondary Accession NumbersNone
Metabolite Identification
Common NameAcridone
DescriptionAcridone, also known as 9(10H)-acridone, belongs to the class of organic compounds known as acridones. These are acridines containing a ketone group attached to the C9 carbon atom of the acridine moiety. Based on a literature review a small amount of articles have been published on Acridone. This compound has been identified in human blood as reported by (PMID: 31557052 ). Acridone is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives. Technically Acridone is part of the human exposome. The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health. An individual's exposure begins before birth and includes insults from environmental and occupational sources.
Structure
Thumb
Synonyms
ValueSource
9,10-Dihydro-9-oxoacridineChEBI
9-AcridoneChEBI
AcridanoneChEBI
9(10H)-AcridoneKegg
9-Azaanthracen-10-oneHMDB
AcridoneMeSH
Chemical FormulaC13H9NO
Average Molecular Weight195.221
Monoisotopic Molecular Weight195.068413914
IUPAC Name9,10-dihydroacridin-9-one
Traditional Nameacridone
CAS Registry NumberNot Available
SMILES
O=C1C2=CC=CC=C2NC2=CC=CC=C12
InChI Identifier
InChI=1S/C13H9NO/c15-13-9-5-1-3-7-11(9)14-12-8-4-2-6-10(12)13/h1-8H,(H,14,15)
InChI KeyFZEYVTFCMJSGMP-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as acridones. These are acridines containing a ketone group attached to the C9 carbon atom of the acridine moiety.
KingdomOrganic compounds
Super ClassOrganoheterocyclic compounds
ClassQuinolines and derivatives
Sub ClassBenzoquinolines
Direct ParentAcridones
Alternative Parents
Substituents
  • Acridone
  • Dihydroquinolone
  • Dihydroquinoline
  • Pyridine
  • Benzenoid
  • Heteroaromatic compound
  • Vinylogous amide
  • Azacycle
  • Organic nitrogen compound
  • Hydrocarbon derivative
  • Organic oxide
  • Organooxygen compound
  • Organonitrogen compound
  • Organopnictogen compound
  • Organic oxygen compound
  • Aromatic heteropolycyclic compound
Molecular FrameworkAromatic heteropolycyclic compounds
External Descriptors
Ontology
Physiological effectNot Available
Disposition
ProcessNot Available
RoleNot Available
Physical Properties
StateNot Available
Experimental Molecular Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Experimental Chromatographic PropertiesNot Available
Predicted Molecular Properties
Predicted Chromatographic Properties
Spectra
Biological Properties
Cellular LocationsNot Available
Biospecimen Locations
  • Blood
Tissue LocationsNot Available
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
BloodDetected but not QuantifiedNot QuantifiedNot SpecifiedNot SpecifiedNormal details
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDNot Available
KNApSAcK IDC00052180
Chemspider ID10188539
KEGG Compound IDC20142
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkAcridone
METLIN IDNot Available
PubChem Compound2015
PDB IDNot Available
ChEBI ID50756
Food Biomarker OntologyNot Available
VMH IDNot Available
MarkerDB IDNot Available
Good Scents IDNot Available
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Barupal DK, Fiehn O: Generating the Blood Exposome Database Using a Comprehensive Text Mining and Database Fusion Approach. Environ Health Perspect. 2019 Sep;127(9):97008. doi: 10.1289/EHP4713. Epub 2019 Sep 26. [PubMed:31557052 ]