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Record Information
Version5.0
StatusDetected but not Quantified
Creation Date2021-09-11 09:01:57 UTC
Update Date2021-09-26 23:03:45 UTC
HMDB IDHMDB0251643
Secondary Accession NumbersNone
Metabolite Identification
Common NameDurohydroquinone
DescriptionDurohydroquinone, also known as duroquinol or dihydroxydurene, belongs to the class of organic compounds known as hydroquinones. Hydroquinones are compounds containing a hydroquinone moiety, which consists of a benzene ring with a hydroxyl groups at positions 1 and 4. Durohydroquinone is a secondary metabolite. Secondary metabolites are metabolically or physiologically non-essential metabolites that may serve a role as defense or signalling molecules. In some cases they are simply molecules that arise from the incomplete metabolism of other secondary metabolites. Based on a literature review a significant number of articles have been published on Durohydroquinone. This compound has been identified in human blood as reported by (PMID: 31557052 ). Durohydroquinone is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives. Technically Durohydroquinone is part of the human exposome. The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health. An individual's exposure begins before birth and includes insults from environmental and occupational sources.
Structure
Thumb
Synonyms
ValueSource
1,4-Dihydroxy-2,3,5,6-tetramethylbenzeneChEBI
2,3,5,6-Tetramethyl-1,4-benzenediolChEBI
2,3,5,6-Tetramethyl-1,4-dihydroquinoneChEBI
2,3,5,6-TetramethylhydroquinoneChEBI
DihydroxydureneChEBI
Duro-p-hydroquinoneChEBI
DuroquinolChEBI
Tetramethyl-1,4-benzoquinolChEBI
Tetramethyl-p-benzoquinolChEBI
Tetramethyl-p-hydroquinoneChEBI
Tetramethylbenzene-1,4-diolChEBI
TetramethylhydroquinoneChEBI
Chemical FormulaC10H14O2
Average Molecular Weight166.22
Monoisotopic Molecular Weight166.099379691
IUPAC Nametetramethylbenzene-1,4-diol
Traditional Nametetramethylbenzene-1,4-diol
CAS Registry NumberNot Available
SMILES
CC1=C(C)C(O)=C(C)C(C)=C1O
InChI Identifier
InChI=1S/C10H14O2/c1-5-6(2)10(12)8(4)7(3)9(5)11/h11-12H,1-4H3
InChI KeySUNVJLYYDZCIIK-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as hydroquinones. Hydroquinones are compounds containing a hydroquinone moiety, which consists of a benzene ring with a hydroxyl groups at positions 1 and 4.
KingdomOrganic compounds
Super ClassBenzenoids
ClassPhenols
Sub ClassBenzenediols
Direct ParentHydroquinones
Alternative Parents
Substituents
  • O-cresol
  • M-cresol
  • Hydroquinone
  • Monocyclic benzene moiety
  • Organic oxygen compound
  • Hydrocarbon derivative
  • Organooxygen compound
  • Aromatic homomonocyclic compound
Molecular FrameworkAromatic homomonocyclic compounds
External DescriptorsNot Available
Ontology
Physiological effectNot Available
Disposition
ProcessNot Available
RoleNot Available
Physical Properties
StateNot Available
Experimental Molecular Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Experimental Chromatographic PropertiesNot Available
Predicted Molecular Properties
Predicted Chromatographic Properties
Spectra
Biological Properties
Cellular LocationsNot Available
Biospecimen Locations
  • Blood
Tissue LocationsNot Available
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
BloodDetected but not QuantifiedNot QuantifiedNot SpecifiedNot SpecifiedNormal details
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDNot Available
KNApSAcK IDNot Available
Chemspider ID120120
KEGG Compound IDNot Available
BioCyc IDCPD-23347
BiGG IDNot Available
Wikipedia LinkNot Available
METLIN IDNot Available
PubChem Compound136346
PDB IDNot Available
ChEBI ID189006
Food Biomarker OntologyNot Available
VMH IDNot Available
MarkerDB IDNot Available
Good Scents IDNot Available
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Barupal DK, Fiehn O: Generating the Blood Exposome Database Using a Comprehensive Text Mining and Database Fusion Approach. Environ Health Perspect. 2019 Sep;127(9):97008. doi: 10.1289/EHP4713. Epub 2019 Sep 26. [PubMed:31557052 ]