Link Details
- Metabolite
- HMDB0000067 (Cholesterol)
- DrugBank ID
- DB00641
- Drug Name
- Simvastatin
- Effect
- Decrease
- Biospecimen
- Blood
- P-value
- Not Available
- Beta Estimator
- Not Available
- Percent Change
- Not Available
- Pearson Correlation Coefficient
- Not Available
- Comments
- Not Available
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- Nakandakare E, Garcia RC, Rocha JC, Sperotto G, Oliveira HC, Quintao EC: Effects of simvastatin, bezafibrate and gemfibrozil on the quantity and composition of plasma lipoproteins. Atherosclerosis. 1990 Dec;85(2-3):211-7. [PubMed:2102085 ]
- Bruckert E, De Gennes JL, Malbecq W, Baigts F: Comparison of the efficacy of simvastatin and standard fibrate therapy in the treatment of primary hypercholesterolemia and combined hyperlipidemia. Clin Cardiol. 1995 Nov;18(11):621-9. [PubMed:8590530 ]
- Ballantyne CM, Olsson AG, Cook TJ, Mercuri MF, Pedersen TR, Kjekshus J: Influence of low high-density lipoprotein cholesterol and elevated triglyceride on coronary heart disease events and response to simvastatin therapy in 4S. Circulation. 2001 Dec 18;104(25):3046-51. [PubMed:11748098 ]
- Stewart MW, Dyer RG, Alberti KG, Laker MF: The effects of lipid lowering drugs on metabolic control and lipoprotein composition in type 2 diabetic patients with mild hyperlipidaemia. Diabet Med. 1995 Mar;12(3):250-7. [PubMed:7758262 ]
- Gavish D, Leibovitz E, Shapira I, Rubinstein A: Bezafibrate and simvastatin combination therapy for diabetic dyslipidaemia: efficacy and safety. J Intern Med. 2000 May;247(5):563-9. [PubMed:10809995 ]
- Lea AP, McTavish D: Atorvastatin. A review of its pharmacology and therapeutic potential in the management of hyperlipidaemias. Drugs. 1997 May;53(5):828-47. [PubMed:9129869 ]
- Skrha J, Stulc T, Hilgertova J, Weiserova H, Kvasnicka J, Ceska R: Effect of simvastatin and fenofibrate on endothelium in Type 2 diabetes. Eur J Pharmacol. 2004 Jun 16;493(1-3):183-9. [PubMed:15189781 ]