Link Details
- Metabolite
- HMDB0000067 (Cholesterol)
- DrugBank ID
- DB01241
- Drug Name
- Gemfibrozil
- Effect
- Decrease
- Biospecimen
- Blood
- P-value
- Not Available
- Beta Estimator
- Not Available
- Percent Change
- Not Available
- Pearson Correlation Coefficient
- Not Available
- Comments
- Not Available
- Zimetbaum P, Frishman WH, Kahn S: Effects of gemfibrozil and other fibric acid derivatives on blood lipids and lipoproteins. J Clin Pharmacol. 1991 Jan;31(1):25-37. [PubMed:2045526 ]
- Durrington PN, Mackness MI, Bhatnagar D, Julier K, Prais H, Arrol S, Morgan J, Wood GN: Effects of two different fibric acid derivatives on lipoproteins, cholesteryl ester transfer, fibrinogen, plasminogen activator inhibitor and paraoxonase activity in type IIb hyperlipoproteinaemia. Atherosclerosis. 1998 May;138(1):217-25. [PubMed:9678787 ]
- Bruckert E, De Gennes JL, Malbecq W, Baigts F: Comparison of the efficacy of simvastatin and standard fibrate therapy in the treatment of primary hypercholesterolemia and combined hyperlipidemia. Clin Cardiol. 1995 Nov;18(11):621-9. [PubMed:8590530 ]
- Hunninghake DB, Peters JR: Effect of fibric acid derivatives on blood lipid and lipoprotein levels. Am J Med. 1987 Nov 27;83(5B):44-9. [PubMed:3318453 ]
- Klosiewicz-Latoszek L, Szostak WB: Comparative studies on the influence of different fibrates on serum lipoproteins in endogenous hyperlipoproteinaemia. Eur J Clin Pharmacol. 1991;40(1):33-41. [PubMed:2060543 ]
- McCullough PA, Ahmed AB, Zughaib MT, Glanz ED, Di Loreto MJ: Treatment of hypertriglyceridemia with fibric acid derivatives: impact on lipid subfractions and translation into a reduction in cardiovascular events. Rev Cardiovasc Med. 2011;12(4):173-85. doi: 10.3909/ricm0619. [PubMed:22249508 ]