Link Details
- Metabolite
- HMDB0000067 (Cholesterol)
- DrugBank ID
- DB00641
- Drug Name
- Simvastatin
- Effect
- Decrease
- Biospecimen
- Blood
- P-value
- Not Available
- Beta Estimator
- Not Available
- Percent Change
- Not Available
- Pearson Correlation Coefficient
- Not Available
- Comments
- Not Available
- Stuyt PM, Mol MJ, Stalenhoef AF, Demacker PN, Van 't Laar A: Simvastatin in the effective reduction of plasma lipoprotein levels in familial dysbetalipoproteinemia (type III hyperlipoproteinemia). Am J Med. 1990 Jan;88(1N):42N-45N. [PubMed:2368763 ]
- Trupp M, Zhu H, Wikoff WR, Baillie RA, Zeng ZB, Karp PD, Fiehn O, Krauss RM, Kaddurah-Daouk R: Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment. PLoS One. 2012;7(7):e38386. doi: 10.1371/journal.pone.0038386. Epub 2012 Jul 9. [PubMed:22808006 ]
- Krauss RM, Zhu H, Kaddurah-Daouk R: Pharmacometabolomics of statin response. Clin Pharmacol Ther. 2013 Nov;94(5):562-5. doi: 10.1038/clpt.2013.164. Epub 2013 Aug 14. [PubMed:23945822 ]