Hmdb loader
Identification
HMDB Protein ID HMDBP00118
Secondary Accession Numbers
  • 5350
  • HMDBP03466
  • HMDBP09542
Name NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
Synonyms
  1. CI-MNLL
  2. Complex I-MNLL
  3. NADH-ubiquinone oxidoreductase MNLL subunit
Gene Name NDUFB1
Protein Type Enzyme
Biological Properties
General Function Involved in NADH dehydrogenase activity
Specific Function Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Pathways Not Available
Reactions Not Available
GO Classification
Component
mitochondrion
organelle
membrane-bounded organelle
intracellular membrane-bounded organelle
Function
catalytic activity
nadh dehydrogenase activity
oxidoreductase activity
oxidoreductase activity, acting on nadh or nadph
Cellular Location
  1. Single-pass membrane protein
  2. Mitochondrion inner membrane
  3. Matrix side
Gene Properties
Chromosome Location Chromosome:1
Locus 14q32.12
SNPs NDUFB1
Gene Sequence
>177 bp
ATGGTGAACTTACTTCAGATTGTGCGGGACCACTGGGTTCATGTTCTTGTCCCTATGGGA
TTTGTCATTGGATGTTATTTAGACAGAAAGAGTGATGAACGGCTAACTGCCTTCCGGAAC
AAGAGTATGTTATTTAAAAGGGAATTGCAACCCAGTGAAGAAGTTACCTGGAAGTAA
Protein Properties
Number of Residues 58
Molecular Weight 6961.2
Theoretical pI 9.34
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • 11-27
Protein Sequence
>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
MVNLLQIVRDHWVHVLVPMGFVIGCYLDRKSDERLTAFRNKSMLFKRELQPSEEVTWK
GenBank ID Protein 5326820
UniProtKB/Swiss-Prot ID O75438
UniProtKB/Swiss-Prot Entry Name NDUB1_HUMAN
PDB IDs Not Available
GenBank Gene ID AF050638
GeneCard ID NDUFB1
GenAtlas ID NDUFB1
HGNC ID HGNC:7695
References
General References
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