Hmdb loader
Identification
HMDB Protein ID HMDBP00174
Secondary Accession Numbers
  • 5406
  • HMDBP03470
Name Acyl carrier protein, mitochondrial
Synonyms
  1. ACP
  2. CI-SDAP
  3. NADH-ubiquinone oxidoreductase 9.6 kDa subunit
Gene Name NDUFAB1
Protein Type Enzyme
Biological Properties
General Function Involved in acyl carrier activity
Specific Function Carrier of the growing fatty acid chain in fatty acid biosynthesis in mitochondria. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain
Pathways Not Available
Reactions Not Available
GO Classification
Function
binding
cofactor binding
carboxylic acid binding
amino acid binding
phosphopantetheine binding
transporter activity
substrate-specific transporter activity
acyl carrier activity
Process
metabolic process
cellular metabolic process
organic acid metabolic process
oxoacid metabolic process
carboxylic acid metabolic process
monocarboxylic acid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
Cellular Location
  1. Mitochondrion
Gene Properties
Chromosome Location Chromosome:1
Locus 16p12.2
SNPs NDUFAB1
Gene Sequence
>471 bp
ATGGCGTCTCGTGTCCTTTCAGCCTATGTCAGCCGCCTGCCCGCGGCCTTTGCGCCGCTG
CCCCGGGTCCGGATGCTGGCCGTGGCCCGGCCTCTCAGCACCGCTCTCTGCTCCGCGGGG
ACCCAGACGAGGCTCGGGACTTTGCAGCCGGCCTTAGTGCTCGCGCAGGTTCCTGGTAGA
GTTACACAGTTGTGCCGCCAGTATAGCGACATGCCTCCTTTGACGTTAGAGGGCATCCAG
GACCGTGTTCTTTACGTATTGAAACTCTATGACAAGATTGACCCAGAGAAGCTTTCAGTA
AATTCTCATTTTATGAAAGACCTGGGCTTAGACAGTTTGGACCAAGTGGAGATTATCATG
GCCATGGAAGACGAATTTGGGTTTGAAATTCCTGATATAGATGCTGAAAAGTTAATGTGT
CCACAAGAAATTGTAGATTACATTGCAGATAAGAAGGATGTATATGAATAA
Protein Properties
Number of Residues 156
Molecular Weight 17417.1
Theoretical pI 4.53
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Acyl carrier protein, mitochondrial
MASRVLSAYVSRLPAAFAPLPRVRMLAVARPLSTALCSAGTQTRLGTLQPALVLAQVPGR
VTQLCRQYSDMPPLTLEGIQDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIM
AMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE
GenBank ID Protein 4826852
UniProtKB/Swiss-Prot ID O14561
UniProtKB/Swiss-Prot Entry Name ACPM_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_005003.2
GeneCard ID NDUFAB1
GenAtlas ID NDUFAB1
HGNC ID HGNC:7694
References
General References
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  5. Murray J, Zhang B, Taylor SW, Oglesbee D, Fahy E, Marusich MF, Ghosh SS, Capaldi RA: The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. J Biol Chem. 2003 Apr 18;278(16):13619-22. Epub 2003 Feb 28. [PubMed:12611891 ]
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