| HMDB0000248 | Thyroxine | 51-48-9 |  | C15H11I4NO4 | 776.87
776.686681525 | Not Available |
| HMDB0014651 | Dextrothyroxine | 51-49-0 |  | C15H11I4NO4 | 776.87
776.686681525 | - Visser TJ: The elemental importance of sufficient iodine intake: a trace is not enough. Endocrinology. 2006 May;147(5):2095-7. [PubMed:16617153 ]
|
| HMDB0000265 | Liothyronine | 6893-02-3 |  | C15H12I3NO4 | 650.9735
650.790038137 | Not Available |
| HMDB0003178 | Heme | 14875-96-8 |  | C34H32FeN4O4 | 616.487
616.177297665 | Not Available |
| HMDB0003474 | 3,5-Diiodo-L-tyrosine | 300-39-0 |  | C9H9I2NO3 | 432.9816
432.867179999 | Not Available |
| HMDB0000021 | Iodotyrosine | 70-78-0 |  | C9H10INO3 | 307.0851
306.970536611 | Not Available |
| HMDB0000675 | Iodine | 7553-56-2 |  | I2 | 253.8089
253.80893684 | Not Available |
| HMDB0014533 | Carbimazole | 22232-54-8 |  | C7H10N2O2S | 186.232
186.046298264 | - Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
- Guilhem I, Massart C, Poirier JY, Maugendre D: Differential evolution of thyroid peroxidase and thyrotropin receptor antibodies in Graves' disease: thyroid peroxidase antibody activity reverts to pretreatment level after carbimazole withdrawal. Thyroid. 2006 Oct;16(10):1041-5. [PubMed:17042691 ]
- Magnusson RP, Taurog A, Dorris ML: Mechanism of iodide-dependent catalatic activity of thyroid peroxidase and lactoperoxidase. J Biol Chem. 1984 Jan 10;259(1):197-205. [PubMed:6706930 ]
- Taurog A: The mechanism of action of the thioureylene antithyroid drugs. Endocrinology. 1976 Apr;98(4):1031-46. [PubMed:1278093 ]
- Perrild H, Gruters-Kieslich A, Feldt-Rasmussen U, Grant D, Martino E, Kayser L, Delange F: Diagnosis and treatment of thyrotoxicosis in childhood. A European questionnaire study. Eur J Endocrinol. 1994 Nov;131(5):467-73. [PubMed:7952157 ]
- Orgiazzi J, Millot L: [Theoretical aspects of the treatment with antithyroid drugs]. Ann Endocrinol (Paris). 1994;55(1):1-5. [PubMed:7528484 ]
- Nakashima T, Taurog A: Rapid conversion of carbimazole to methimazole in serum; evidence for an enzymatic mechanism. Clin Endocrinol (Oxf). 1979 Jun;10(6):637-48. [PubMed:476986 ]
- Humar M, Dohrmann H, Stein P, Andriopoulos N, Goebel U, Roesslein M, Schmidt R, Schwer CI, Loop T, Geiger KK, Pahl HL, Pannen BH: Thionamides inhibit the transcription factor nuclear factor-kappaB by suppression of Rac1 and inhibitor of kappaB kinase alpha. J Pharmacol Exp Ther. 2008 Mar;324(3):1037-44. Epub 2007 Nov 30. [PubMed:18055877 ]
|
| HMDB0000158 | L-Tyrosine | 60-18-4 |  | C9H11NO3 | 181.1885
181.073893223 | Not Available |
| HMDB0014690 | Propylthiouracil | 51-52-5 |  | C7H10N2OS | 170.232
170.051383642 | - Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
- Sugawara M, Sugawara Y, Wen K: Methimazole and propylthiouracil increase cellular thyroid peroxidase activity and thyroid peroxidase mRNA in cultured porcine thyroid follicles. Thyroid. 1999 May;9(5):513-8. [PubMed:10365684 ]
- Manzon RG, Holmes JA, Youson JH: Variable effects of goitrogens in inducing precocious metamorphosis in sea lampreys (Petromyzon marinus). J Exp Zool. 2001 Apr 15;289(5):290-303. [PubMed:11241400 ]
- Ferreira AC, de Carvalho Cardoso L, Rosenthal D, de Carvalho DP: Thyroid Ca2+/NADPH-dependent H2O2 generation is partially inhibited by propylthiouracil and methimazole. Eur J Biochem. 2003 Jun;270(11):2363-8. [PubMed:12755690 ]
- Schmutzler C, Bacinski A, Gotthardt I, Huhne K, Ambrugger P, Klammer H, Schlecht C, Hoang-Vu C, Gruters A, Wuttke W, Jarry H, Kohrle J: The ultraviolet filter benzophenone 2 interferes with the thyroid hormone axis in rats and is a potent in vitro inhibitor of human recombinant thyroid peroxidase. Endocrinology. 2007 Jun;148(6):2835-44. Epub 2007 Mar 22. [PubMed:17379648 ]
- Taurog A, Dorris ML: A reexamination of the proposed inactivation of thyroid peroxidase in the rat thyroid by propylthiouracil. Endocrinology. 1989 Jun;124(6):3038-42. [PubMed:2656250 ]
|
| HMDB0059634 | I(-) | |  | HI | 127.9124
127.912293452 | Not Available |
| HMDB0012238 | Iodide | 20461-54-5 |  | I | 126.9045
126.90446842 | Not Available |
| HMDB0014901 | Methimazole | 60-56-0 |  | C4H6N2S | 114.169
114.025168892 | - Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
- Sugawara M, Sugawara Y, Wen K: Methimazole and propylthiouracil increase cellular thyroid peroxidase activity and thyroid peroxidase mRNA in cultured porcine thyroid follicles. Thyroid. 1999 May;9(5):513-8. [PubMed:10365684 ]
- Manzon RG, Holmes JA, Youson JH: Variable effects of goitrogens in inducing precocious metamorphosis in sea lampreys (Petromyzon marinus). J Exp Zool. 2001 Apr 15;289(5):290-303. [PubMed:11241400 ]
- Ferreira AC, de Carvalho Cardoso L, Rosenthal D, de Carvalho DP: Thyroid Ca2+/NADPH-dependent H2O2 generation is partially inhibited by propylthiouracil and methimazole. Eur J Biochem. 2003 Jun;270(11):2363-8. [PubMed:12755690 ]
- Magnusson RP, Yu B, Brennan V: Effect of serum thyrotropin levels on the concentration of messenger RNA for thyroid peroxidase in the rat. Acta Endocrinol (Copenh). 1992 May;126(5):460-6. [PubMed:1320313 ]
- Chiovato L, Pinchera A: The microsomal/peroxidase antigen: modulation of its expression in thyroid cells. Autoimmunity. 1991;10(4):319-31. [PubMed:1663395 ]
|
| HMDB0003609 | 2-Aminoacrylic acid | 28453-71-6 |  | C3H5NO2 | 87.0773
87.032028409 | Not Available |
| HMDB0012974 | Hypothiocyanite | 63296-34-4 |  | CHNOS | 75.09
74.977884349 | Not Available |
| HMDB0000692 | Fe2+ | 15438-31-0 |  | Fe | 55.845
55.934942133 | Not Available |
| HMDB0000464 | Calcium | 7440-70-2 |  | Ca | 40.078
39.962591155 | Not Available |
| HMDB0003125 | Hydrogen peroxide | 7722-84-1 |  | H2O2 | 34.0147
34.005479308 | Not Available |
| HMDB0002111 | Water | 7732-18-5 |  | H2O | 18.0153
18.010564686 | Not Available |
| HMDB0059597 | Hydrogen Ion | |  | H | 1.0079
1.007825032 | Not Available |
