Hmdb loader
Identification
HMDB Protein ID HMDBP01318
Secondary Accession Numbers
  • 6614
Name Proto-oncogene serine/threonine-protein kinase mos
Synonyms
  1. Oocyte maturation factor mos
  2. Proto-oncogene c-Mos
Gene Name MOS
Protein Type Enzyme
Biological Properties
General Function Involved in protein kinase activity
Specific Function ATP + a protein = ADP + a phosphoprotein
Pathways Not Available
Reactions Not Available
GO Classification
Function
binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
protein kinase activity
protein serine/threonine kinase activity
Process
phosphorus metabolic process
phosphate metabolic process
metabolic process
cellular metabolic process
protein amino acid phosphorylation
phosphorylation
Cellular Location Not Available
Gene Properties
Chromosome Location Chromosome:8
Locus 8q11
SNPs MOS
Gene Sequence
>1041 bp
ATGCCCTCGCCCCTGGCCCTACGCCCCTACCTCCGGAGCGAGTTTTCCCCATCGGTGGAC
GCGCGGCCCTGCAGCAGTCCCTCAGAGCTACCTGCGAAGCTGCTTCTGGGGGCCACTCTT
CCTCGGGCCCCGCGGCTGCCGCGCCGGCTGGCCTGGTGCTCCATTGACTGGGAGCAGGTG
TGCTTGCTGCAGAGGCTGGGAGCTGGAGGGTTTGGCTCGGTGTACAAGGCGACTTACCGC
GGTGTTCCTGTGGCCATAAAGCAAGTGAACAAGTGCACCAAGAACCGACTAGCATCTCGG
CGGAGTTTCTGGGCTGAGCTCAACGTAGCAAGGCTGCGCCACGATAACATCGTGCGCGTG
GTGGCTGCCAGCACGCGCACGCCCGCAGGGTCCAATAGCCTAGGGACCATCATCATGGAG
TTCGGTGGCAACGTCACTTTACACCAAGTCATCTATGGCGCCGCCGGCCACCCTGAGGGG
GACGCAGGGGAGCCTCACTGCCGCACTGGAGGACAGTTAAGTTTGGGAAAGTGTCTCAAG
TACTCACTAGATGTTGTGAACGGCCTGCTCTTCCTCCACTCGCAAAGCATTGTGCACTTG
GACCTGAAGCCCGCGAACATCTTGATCAGTGAGCAGGATGTCTGTAAAATTAGTGACTTC
GGTTGCTCTGAGAAGTTGGAAGATCTGCTGTGCTTCCAGACACCCTCTTACCCTCTAGGA
GGCACATACACCCACCGCGCCCCGGAGCTCCTGAAAGGAGAGGGCGTGACGCCTAAAGCC
GACATTTATTCCTTTGCCATCACTCTCTGGCAAATGACTACCAAGCAGGCGCCGTATTCG
GGGGAGCGGCAGCACATACTGTACGCGGTGGTGGCCTACGACCTGCGCCCGTCCCTCTCC
GCTGCCGTCTTCGAGGACTCGCTCCCCGGGCAGCGCCTTGGGGACGTCATCCAGCGCTGC
TGGAGACCCAGCGCGGCGCAGAGGCCGAGCGCGCGGCTGCTTTTGGTGGATCTCACCTCT
TTGAAAGCTGAACTCGGCTGA
Protein Properties
Number of Residues 346
Molecular Weight 37819.2
Theoretical pI 9.1
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Proto-oncogene serine/threonine-protein kinase mos
MPSPLALRPYLRSEFSPSVDARPCSSPSELPAKLLLGATLPRAPRLPRRLAWCSIDWEQV
CLLQRLGAGGFGSVYKATYRGVPVAIKQVNKCTKNRLASRRSFWAELNVARLRHDNIVRV
VAASTRTPAGSNSLGTIIMEFGGNVTLHQVIYGAAGHPEGDAGEPHCRTGGQLSLGKCLK
YSLDVVNGLLFLHSQSIVHLDLKPANILISEQDVCKISDFGCSEKLEDLLCFQTPSYPLG
GTYTHRAPELLKGEGVTPKADIYSFAITLWQMTTKQAPYSGERQHILYAVVAYDLRPSLS
AAVFEDSLPGQRLGDVIQRCWRPSAAQRPSARLLLVDLTSLKAELG
GenBank ID Protein 47481123
UniProtKB/Swiss-Prot ID P00540
UniProtKB/Swiss-Prot Entry Name MOS_HUMAN
PDB IDs Not Available
GenBank Gene ID BC069569
GeneCard ID MOS
GenAtlas ID MOS
HGNC ID HGNC:7199
References
General References
  1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]
  2. Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew YE, DeFazio A, Greaves MF, Green AR, Campbell P, Birney E, Easton DF, Chenevix-Trench G, Tan MH, Khoo SK, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR: Patterns of somatic mutation in human cancer genomes. Nature. 2007 Mar 8;446(7132):153-8. [PubMed:17344846 ]
  3. Watson R, Oskarsson M, Vande Woude GF: Human DNA sequence homologous to the transforming gene (mos) of Moloney murine sarcoma virus. Proc Natl Acad Sci U S A. 1982 Jul;79(13):4078-82. [PubMed:6287464 ]