Showing Protein Cadherin-15 (HMDBP02921)

• 8429

1. Cadherin-14
2. M-cadherin
3. Muscle cadherin

1. Cell membrane
2. Single-pass type I membrane protein

>2445 bp
ATGGACGCCGCGTTCCTCCTCGTCCTCGGGCTGTTGGCCCAGAGCCTCTGCCTGTCTTTG
GGGGTTCCTGGATGGAGGAGGCCCACCACCCTGTACCCCTGGCGCCGGGCGCCTGCCCTG
AGCCGCGTGCGGAGGGCCTGGGTCATCCCCCCGATCAGCGTATCCGAGAACCACAAGCGT
CTCCCCTACCCCCTGGTTCAGATCAAGTCGGACAAGCAGCAGCTGGGCAGCGTCATCTAC
AGCATCCAGGGACCCGGCGTGGATGAGGAGCCCCGGGGCGTCTTCTCTATCGACAAGTTC
ACAGGGAAGGTCTTCCTCAATGCCATGCTGGACCGCGAGAAGACTGATCGCTTCAGGCTA
AGAGCGTTTGCCCTGGACCTGGGAGGATCCACCCTGGAGGACCCCACGGACCTGGAGATT
GTAGTTGTGGATCAGAATGACAACCGGCCAGCCTTCCTGCAGGAGGCGTTCACTGGCCGC
GTGCTGGAGGGTGCAGTCCCAGGCACCTATGTGACCAGGGCAGAGGCCACAGATGCCGAC
GACCCCGAGACGGACAACGCAGCGCTGCGGTTCTCCATCCTGCAGCAGGGCAGCCCCGAG
CTCTTCAGCATCGACGAGCTCACAGGAGAGATCCGCACAGTGCAAGTGGGGCTGGACCGC
GAGGTGGTCGCGGTGTACAATCTGACCCTGCAGGTGGCGGACATGTCTGGAGACGGCCTC
ACAGCCACTGCCTCAGCCATCATCACCCTTGATGACATCAATGACAATGCCCCCGAGTTC
ACCAGGGATGAGTTCTTCATGGAGGCCATAGAGGCCGTCAGCGGAGTGGATGTGGGACGC
CTGGAAGTGGAGGACAGGGACCTGCCAGGCTCCCCAAACTGGGTGGCCAGGTTCACTATC
CTGGAAGGCGACCCCGATGGGCAGTTCACCATCCGCACGGACCCCAAGACCAACGAGGGT
GTTCTGTCCATTGTGAAGGCCCTGGACTATGAGAGCTGTGAACACTACGAACTCAAAGTG
TCGGTGCAGAATGAGGCCCCGCTGCAGGCGGCTGCCCTTAGGGCTGAGCGGGGCCAGGCC
AAGGTCCGCGTGCATGTGCAGGACACCAACGAGCCCCCCGTGTTCCAGGAGAACCCACTT
CGGACCAGCCTAGCAGAGGGGGCACCCCCAGGCACTCTGGTGGCCACCTTCTCTGCCCGG
GACCCTGACACAGAGCAGCTGCAGAGGCTCAGCTACTCCAAGGACTACGACCCGGAAGAC
TGGCTGCAAGTGGACGCAGCCACTGGCCGGATCCAGACCCAGCACGTGCTCAGCCCGGCG
TCCCCCTTCCTCAAGGGCGGCTGGTACAGAGCCATCGTCCTGGCCCAGGATGACGCCTCC
CAGCCCCGCACCGCCACCGGCACCCTGTCCATCGAGATCCTGGAGGTGAACGACCATGCA
CCTGTGCTGGCCCCGCCGCCGCCGGGCAGCCTGTGCAGCGAGCCACACCAAGGCCCAGGC
CTCCTCCTGGGCGCCACGGATGAGGACCTGCCCCCCCACGGGGCCCCCTTCCACTTCCAG
CTGAGCCCCAGGCTCCCAGAGCTCGGCCGGAACTGGAGCCTCAGCCAGGTCAACGTGAGC
CACGCGCGCCTGCGGCCGCGACACCAGGTCCCCGAAGGCCTGCACCGCCTCAGCCTGCTG
CTCCGGGACTCGGGGCAGCCGCCCCAGCAGCGCGAGCAGCCTCTGAACGTGACCGTGTGC
CGCTGCGGCAAGGACGGCGTCTGCCTGCCGGGGGCCGCAGCGCTGCTGGCGGGGGGCACA
GGCCTCAGCCTGGGCGCACTGGTCATCGTGCTGGCCAGCGCCCTCCTGCTGCTGGTGCTG
GTCCTGCTCGTGGCACTCCGGGCGCGGTTCTGGAAGCAGTCTCGGGGCAAGGGGCTGCTG
CACGGCCCCCAGGACGACCTTCGAGACAATGTCCTCAACTACGATGAGCAAGGAGGCGGG
GAGGAGGACCAGGACGCCTACGACATCAGCCAGCTGCGTCACCCGACAGCGCTGAGCCTG
CCTCTGGGACCGCCGCCACTTCGCAGAGATGCCCCGCAGGGCCGCCTGCACCCCCAGCCA
CCCCGAGTGCTGCCCACCAGCCCCCTGGACATCGCCGACTTCATCAATGATGGCTTGGAG
GCTGCAGATAGTGACCCCAGTGTGCCGCCTTACGACACAGCCCTCATCTATGACTACGAG
GGTGACGGCTCGGTGGCGGGGACGCTGAGCTCCATCCTGTCCAGCCAGGGCGATGAGGAC
CAGGACTACGACTACCTCAGAGACTGGGGGCCCCGCTTCGCCCGGCTGGCAGACATGTAT
GGGCACCCGTGCGGGTTGGAGTACGGGGCCAGATGGGACCACCAGGCCAGGGAGGGTCTT
TCTCCTGGGGCACTGCTACCCAGACACAGAGGCCGGACAGCCTGA

• Cadherin (PF00028 )
• Cadherin_C (PF01049 )

• 1-21

• 607-626

>Cadherin-15
MDAAFLLVLGLLAQSLCLSLGVPGWRRPTTLYPWRRAPALSRVRRAWVIPPISVSENHKR
LPYPLVQIKSDKQQLGSVIYSIQGPGVDEEPRGVFSIDKFTGKVFLNAMLDREKTDRFRL
RAFALDLGGSTLEDPTDLEIVVVDQNDNRPAFLQEAFTGRVLEGAVPGTYVTRAEATDAD
DPETDNAALRFSILQQGSPELFSIDELTGEIRTVQVGLDREVVAVYNLTLQVADMSGDGL
TATASAIITLDDINDNAPEFTRDEFFMEAIEAVSGVDVGRLEVEDRDLPGSPNWVARFTI
LEGDPDGQFTIRTDPKTNEGVLSIVKALDYESCEHYELKVSVQNEAPLQAAALRAERGQA
KVRVHVQDTNEPPVFQENPLRTSLAEGAPPGTLVATFSARDPDTEQLQRLSYSKDYDPED
WLQVDAATGRIQTQHVLSPASPFLKGGWYRAIVLAQDDASQPRTATGTLSIEILEVNDHA
PVLAPPPPGSLCSEPHQGPGLLLGATDEDLPPHGAPFHFQLSPRLPELGRNWSLSQVNVS
HARLRPRHQVPEGLHRLSLLLRDSGQPPQQREQPLNVTVCRCGKDGVCLPGAAALLAGGT
GLSLGALVIVLASALLLLVLVLLVALRARFWKQSRGKGLLHGPQDDLRDNVLNYDEQGGG
EEDQDAYDISQLRHPTALSLPLGPPPLRRDAPQGRLHPQPPRVLPTSPLDIADFINDGLE
AADSDPSVPPYDTALIYDYEGDGSVAGTLSSILSSQGDEDQDYDYLRDWGPRFARLADMY
GHPCGLEYGARWDHQAREGLSPGALLPRHRGRTA

1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]
2. Shibata T, Shimoyama Y, Gotoh M, Hirohashi S: Identification of human cadherin-14, a novel neurally specific type II cadherin, by protein interaction cloning. J Biol Chem. 1997 Feb 21;272(8):5236-40. [PubMed:9030594 ]
3. Bhalla K, Luo Y, Buchan T, Beachem MA, Guzauskas GF, Ladd S, Bratcher SJ, Schroer RJ, Balsamo J, DuPont BR, Lilien J, Srivastava AK: Alterations in CDH15 and KIRREL3 in patients with mild to severe intellectual disability. Am J Hum Genet. 2008 Dec;83(6):703-13. doi: 10.1016/j.ajhg.2008.10.020. Epub 2008 Nov 13. [PubMed:19012874 ]