Showing Protein Xylosyltransferase 1 (HMDBP03016)
| Identification | ||||||||||
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| HMDB Protein ID | HMDBP03016 | |||||||||
| Secondary Accession Numbers |
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| Name | Xylosyltransferase 1 | |||||||||
| Synonyms |
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| Gene Name | XYLT1 | |||||||||
| Protein Type | Enzyme | |||||||||
| Biological Properties | ||||||||||
| General Function | Involved in acetylglucosaminyltransferase activity | |||||||||
| Specific Function | Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes | |||||||||
| Pathways | Not Available | |||||||||
| Reactions | Not Available | |||||||||
| GO Classification |
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| Cellular Location |
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| Gene Properties | ||||||||||
| Chromosome Location | Chromosome:1 | |||||||||
| Locus | 16p12.3 | |||||||||
| SNPs | XYLT1 | |||||||||
| Gene Sequence |
>2880 bp ATGGTGGCGGCGCCGTGCGCCCGGAGGCTGGCCCGGCGCTCGCACTCGGCGCTGCTCGCG GCGCTCACGGTGCTGCTGCTGCAGACGCTGGTCGTGTGGAATTTCAGCAGCCTCGACTCC GGGGCCGGGGAGCGCCGCGGGGGCGCAGCGGTCGGCGGCGGGGAGCAGCCGCCCCCGGCC CCGGCCCCGCGCCGGGAGCGCCGGGACCTGCCCGCCGAGCCGGCTGCAGCCCGAGGAGGA GGAGGAGGCGGCGGCGGAGGAGGAGGAGGACGGGGGCCCCAGGCGCGGGCGCGGGGAGGC GGCCCCGGAGAACCGCGGGGACAGCAGCCGGCCAGCCGGGGGGCACTGCCCGCCCGGGCT CTGGATCCACACCCAAGTCCGCTCATCACCCTGGAGACTCAGGATGGCTACTTTTCTCAT CGGCCGAAAGAGAAAGTGCGAACAGACAGCAACAACGAGAACTCTGTCCCCAAAGACTTT GAGAATGTCGACAACAGCAACTTCGCACCCAGGACTCAAAAGCAGAAGCACCAGCCTGAG TTGGCGAAGAAGCCACCGAGTAGACAGAAGGAGCTTTTGAAAAGGAAGCTGGAACAGCAG GAGAAAGGAAAAGGACATACATTCCCTGGGAAAGGCCCCGGTGAGGTGCTGCCTCCCGGG GACAGAGCCGCAGCCAACAGCAGCCACGGGAAGGATGTGTCCAGACCGCCTCATGCCAGG AAAACTGGGGGCAGCTCCCCCGAGACCAAGTATGACCAGCCCCCTAAGTGTGACATCTCA GGCAAGGAGGCCATCTCTGCCCTGTCCCGTGCTAAGTCCAAGCACTGCCGCCAGGAGATT GGGGAGACTTACTGCCGCCACAAGTTAGGGCTGCTGATGCCTGAGAAGGTGACTCGGTTC TGCCCCCTCGAGGGTAAAGCCAACAAGAACGTGCAGTGGGACGAGGACTCCGTGGAGTAC ATGCCAGCCAACCCGGTCAGAATCGCCTTTGTCCTGGTGGTCCACGGCCGTGCCTCTCGG CAGTTGCAGCGCATGTTCAAGGCCATCTACCACAAAGACCACTTCTACTACATCCACGTG GACAAGCGCTCTAATTACCTGCATCGGCAAGTGCTCCAGGTCTCCAGGCAGTACAGCAAT GTCCGCGTCACCCCCTGGAGAATGGCCACCATCTGGGGAGGAGCCAGCCTCCTGTCCACC TACCTGCAGAGCATGCGGGACCTCCTGGAGATGACCGACTGGCCCTGGGACTTCTTCATC AACCTGAGTGCGGCCGACTACCCCATCAGGACAAATGACCAGTTGGTGGCGTTTCTCTCC CGATACCGAGATATGAATTTCTTGAAGTCACACGGCCGGGACAATGCAAGGTTCATTCGG AAGCAGGGCCTGGATCGGCTCTTCCTGGAGTGCGACGCTCACATGTGGCGCCTGGGAGAT CGGCGGATCCCAGAGGGCATTGCCGTGGATGGCGGTTCGGACTGGTTCCTGCTGAACCGG AGGTTTGTAGAATATGTGACCTTCTCCACAGACGATCTGGTGACCAAGATGAAACAGTTC TACTCCTACACCCTGCTTCCTGCTGAGTCCTTCTTCCATACGGTCCTGGAGAACAGCCCC CACTGCGACACCATGGTGGACAACAACCTGCGCATCACCAACTGGAATCGCAAGCTGGGC TGCAAGTGCCAGTACAAGCACATCGTGGACTGGTGCGGCTGCTCCCCCAATGACTTCAAG CCGCAGGACTTCCACCGCTTCCAGCAGACAGCCCGGCCTACCTTCTTTGCCCGCAAGTTT GAAGCCGTGGTGAATCAGGAAATCATTGGGCAGCTGGACTATTACCTGTACGGGAACTAC CCTGCAGGTACCCCGGGCCTGCGCTCCTACTGGGAGAATGTCTACGATGAGCCTGACGGC ATCCACAGCCTGAGCGACGTGACACTCACCTTGTACCACTCCTTTGCCCGCCTGGGTCTT CGACGGGCCGAGACGTCCCTGCACACGGATGGGGAGAACAGCTGCCGATACTACCCAATG GGCCACCCAGCATCTGTGCACCTCTACTTCCTTGCTGACCGCTTCCAGGGCTTTCTGATC AAGCATCATGCTACCAATCTGGCTGTGAGCAAACTAGAGACTCTGGAGACCTGGGTGATG CCGAAAAAAGTCTTCAAGATCGCAAGCCCACCCAGTGACTTTGGGAGGCTTCAGTTTTCC GAGGTCGGCACTGACTGGGATGCCAAGGAGAGGCTATTCCGCAACTTTGGGGGTCTTCTG GGGCCCATGGATGAGCCGGTGGGTATGCAGAAGTGGGGGAAGGGACCTAATGTGACCGTG ACCGTCATTTGGGTGGATCCCGTCAATGTCATCGCAGCCACCTACGACATCCTCATTGAG TCCACTGCCGAATTCACACACTACAAGCCCCCTTTGAACTTGCCCCTGAGGCCTGGGGTC TGGACAGTGAAAATTCTCCACCACTGGGTGCCAGTTGCAGAGACCAAATTCCTCGTTGCG CCTCTGACCTTCTCGAACAGGCAGCCCATCAAACCTGAGGAGGCACTGAAGCTGCACAAT GGGCCCCTCCGCAATGCCTACATGGAGCAGAGCTTCCAGAGCCTAAACCCCGTCCTCAGC CTGCCCATCAACCCCGCCCAGGTGGAACAGGCACGGAGGAACGCAGCCTCCACGGGCACA GCGCTGGAGGGATGGCTGGACTCGTTGGTGGGCGGGATGTGGACTGCCATGGACATCTGT GCCACGGGCCCCACAGCCTGCCCGGTCATGCAGACCTGCAGCCAGACGGCCTGGAGCTCC TTCAGCCCTGACCCCAAGTCGGAGCTGGGGGCAGTCAAACCTGATGGCCGGCTCAGGTAG |
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| Protein Properties | ||||||||||
| Number of Residues | 959 | |||||||||
| Molecular Weight | 107568.4 | |||||||||
| Theoretical pI | 9.61 | |||||||||
| Pfam Domain Function |
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| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Xylosyltransferase 1 MVAAPCARRLARRSHSALLAALTVLLLQTLVVWNFSSLDSGAGERRGGAAVGGGEQPPPA PAPRRERRDLPAEPAAARGGGGGGGGGGGGRGPQARARGGGPGEPRGQQPASRGALPARA LDPHPSPLITLETQDGYFSHRPKEKVRTDSNNENSVPKDFENVDNSNFAPRTQKQKHQPE LAKKPPSRQKELLKRKLEQQEKGKGHTFPGKGPGEVLPPGDRAAANSSHGKDVSRPPHAR KTGGSSPETKYDQPPKCDISGKEAISALSRAKSKHCRQEIGETYCRHKLGLLMPEKVTRF CPLEGKANKNVQWDEDSVEYMPANPVRIAFVLVVHGRASRQLQRMFKAIYHKDHFYYIHV DKRSNYLHRQVLQVSRQYSNVRVTPWRMATIWGGASLLSTYLQSMRDLLEMTDWPWDFFI NLSAADYPIRTNDQLVAFLSRYRDMNFLKSHGRDNARFIRKQGLDRLFLECDAHMWRLGD RRIPEGIAVDGGSDWFLLNRRFVEYVTFSTDDLVTKMKQFYSYTLLPAESFFHTVLENSP HCDTMVDNNLRITNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFHRFQQTARPTFFARKF EAVVNQEIIGQLDYYLYGNYPAGTPGLRSYWENVYDEPDGIHSLSDVTLTLYHSFARLGL RRAETSLHTDGENSCRYYPMGHPASVHLYFLADRFQGFLIKHHATNLAVSKLETLETWVM PKKVFKIASPPSDFGRLQFSEVGTDWDAKERLFRNFGGLLGPMDEPVGMQKWGKGPNVTV TVIWVDPVNVIAATYDILIESTAEFTHYKPPLNLPLRPGVWTVKILHHWVPVAETKFLVA PLTFSNRQPIKPEEALKLHNGPLRNAYMEQSFQSLNPVLSLPINPAQVEQARRNAASTGT ALEGWLDSLVGGMWTAMDICATGPTACPVMQTCSQTAWSSFSPDPKSELGAVKPDGRLR |
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| External Links | ||||||||||
| GenBank ID Protein | 28269693 | |||||||||
| UniProtKB/Swiss-Prot ID | Q86Y38 | |||||||||
| UniProtKB/Swiss-Prot Entry Name | XYLT1_HUMAN | |||||||||
| PDB IDs | Not Available | |||||||||
| GenBank Gene ID | NM_022166.3 | |||||||||
| GeneCard ID | XYLT1 | |||||||||
| GenAtlas ID | XYLT1 | |||||||||
| HGNC ID | HGNC:15516 | |||||||||
| References | ||||||||||
| General References |
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