Showing Protein Sodium/calcium exchanger 2 (HMDBP03171)
Identification | ||||||||||||||||||||||||||||
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HMDB Protein ID | HMDBP03171 | |||||||||||||||||||||||||||
Secondary Accession Numbers |
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Name | Sodium/calcium exchanger 2 | |||||||||||||||||||||||||||
Synonyms |
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Gene Name | SLC8A2 | |||||||||||||||||||||||||||
Protein Type | Unknown | |||||||||||||||||||||||||||
Biological Properties | ||||||||||||||||||||||||||||
General Function | Involved in cell communication | |||||||||||||||||||||||||||
Specific Function | Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores | |||||||||||||||||||||||||||
Pathways | Not Available | |||||||||||||||||||||||||||
Reactions | Not Available | |||||||||||||||||||||||||||
GO Classification |
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Cellular Location |
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Gene Properties | ||||||||||||||||||||||||||||
Chromosome Location | Chromosome:1 | |||||||||||||||||||||||||||
Locus | 19q13.3 | |||||||||||||||||||||||||||
SNPs | SLC8A2 | |||||||||||||||||||||||||||
Gene Sequence |
>2766 bp ATGGCTCCCCTGGCCTTGGTGGGGGTCACACTCCTCCTGGCGGCTCCCCCATGCTCCGGG GCAGCCACCCCAACCCCCTCCCTGCCGCCTCCCCCGGCCAATGACAGCGACACCAGCACA GGGGGCTGCCAGGGGTCCTACCGCTGCCAGCCGGGGGTGCTGCTGCCCGTGTGGGAGCCC GACGACCCGTCGCTGGGTGACAAGGCGGCACGGGCAGTGGTGTACTTTGTGGCCATGGTC TACATGTTTCTGGGAGTGTCCATCATCGCCGACCGTTTCATGGCGGCCATCGAGGTCATC ACGTCAAAAGAGAAGGAGATCACCATCACCAAGGCCAACGGTGAGACCAGCGTGGGCACC GTTCGCATCTGGAATGAGACGGTGTCCAACCTCACGCTCATGGCCCTGGGCTCCTCCGCA CCTGAGATCCTGCTGTCAGTCATCGAAGTCTGCGGCCACAACTTCCAGGCGGGTGAGCTG GGCCCAGGCACCATCGTGGGCAGCGCTGCCTTCAACATGTTTGTGGTCATCGCCGTGTGC ATCTACGTCATCCCAGCCGGCGAGAGCCGCAAGATCAAGCACCTGAGAGTCTTCTTTGTC ACTGCCTCTTGGAGCATCTTCGCCTATGTCTGGCTTTATCTCATCCTTGCTGTTTTTTCC CCCGGTGTGGTCCAGGTGTGGGAGGCGCTGCTGACCCTGGTCTTCTTCCCGGTGTGCGTG GTATTCGCCTGGATGGCCGACAAGCGGCTGCTCTTCTACAAGTACGTGTACAAGCGCTAC CGCACCGACCCACGCAGCGGCATCATCATAGGCGCCGAGGGCGACCCCCCGAAGAGCATC GAGCTGGACGGCACGTTCGTGGGCGCCGAGGCCCCAGGTGAGCTGGGCGGCCTGGGCCCG GGCCCCGCCGAGGCGCGCGAGCTGGACGCCAGCCGCCGCGAGGTCATCCAGATCCTCAAG GACCTCAAGCAGAAGCACCCGGACAAGGATCTGGAGCAGCTGGTGGGCATCGCCAACTAC TACGCGCTGCTGCACCAGCAGAAGAGCCGCGCCTTCTACCGCATCCAGGCCACGCGGCTG ATGACCGGCGCCGGGAACGTGCTGCGCAGACACGCGGCGGACGCCTCGCGCAGGGCGGCG CCGGCCGAGGGCGCGGGCGAGGACGAAGACGACGGCGCCAGCCGCATCTTCTTCGAGCCT AGCCTCTACCACTGCCTGGAGAACTGCGGCTCCGTGCTGCTGTCCGTCACGTGCCAGGGC GGCGAGGGCAACAGCACCTTCTACGTGGACTACCGCACTGAGGACGGCTCTGCCAAGGCG GGCTCCGACTACGAGTACAGCGAGGGCACGCTGGTGTTCAAACCAGGCGAGACGCAGAAG GAGCTGCGCATCGGCATCATCGACGACGACATCTTCGAGGAGGACGAGCATTTCTTCGTG CGGCTGCTGAACCTGCGCGTGGGCGACGCGCAGGGCATGTTCGAGCCGGACGGCGGCGGG CGGCCCAAGGGGCGGCTGGTGGCGCCGCTGCTGGCCACCGTCACCATCCTGGACGACGAC CACGCAGGCATCTTCTCCTTCCAGGACCGCCTGCTGCACGTGAGCGAGTGCATGGGCACC GTGGACGTGCGCGTCGTGCGCAGCTCGGGCGCGCGCGGCACCGTGCGCCTTCCCTACCGC ACGGTGGACGGCACGGCGCGCGGCGGCGGCGTGCACTACGAGGACGCGTGCGGAGAGCTG GAGTTTGGCGACGACGAGACCATGAAAACTCTTCAGGTGAAGATAGTTGATGACGAGGAA TATGAGAAAAAGGATAATTTCTTCATTGAGCTGGGCCAGCCCCAGTGGCTTAAGCGAGGG ATTTCAGCTCTGCTACTCAATCAAGGGGATGGGGACAGGAAGCTAACAGCCGAGGAGGAG GAGGCTCGGAGGATAGCAGAGATGGGCAAGCCAGTTCTTGGGGAGAACTGCCGGCTGGAG GTCATCATCGAGGAGTCATATGATTTTAAGAACACGGTGGATAAACTCATCAAGAAAACG AACTTGGCCTTGGTAATTGGGACCCATTCATGGAGGGAGCAGTTTTTAGAGGCAATTACG GTGAGCGCAGGGGACGAGGAGGAGGAGGAGGACGGGTCCCGGGAGGAGCGGCTGCCGTCG TGCTTTGACTACGTGATGCACTTCCTGACGGTGTTCTGGAAGGTGCTCTTCGCCTGTGTG CCCCCCACCGAGTACTGCCACGGCTGGGCCTGCTTTGGTGTCTCCATCCTGGTCATCGGC CTGCTCACCGCCCTCATTGGGGACCTCGCCTCCCACTTCGGCTGCACCGTTGGCCTCAAG GACTCTGTCAATGCTGTTGTCTTCGTTGCCCTGGGCACCTCCATCCCTGACACGTTCGCC AGCAAGGTGGCGGCGCTGCAGGACCAGTGCGCCGACGCGTCCATCGGCAACGTGACCGGC TCCAACGCGGTGAACGTGTTCCTTGGCCTGGGCGTCGCCTGGTCTGTGGCCGCCGTGTAC TGGGCGGTGCAGGGCCGCCCCTTCGAGGTGCGCACTGGCACGCTGGCCTTCTCCGTCACG CTCTTCACCGTCTTCGCCTTCGTGGGCATTGCCGTGCTGCTGTACCGGCGCCGGCCGCAC ATCGGCGGCGAGCTGGGCGGCCCGCGCGGACCCAAGCTCGCCACCACCGCGCTCTTCCTG GGCCTCTGGCTCCTGTACATCCTCTTCGCCAGCCTGGAGGCGTACTGCCACATCCGGGGC TTCTAG |
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Protein Properties | ||||||||||||||||||||||||||||
Number of Residues | 921 | |||||||||||||||||||||||||||
Molecular Weight | 100366.9 | |||||||||||||||||||||||||||
Theoretical pI | 4.78 | |||||||||||||||||||||||||||
Pfam Domain Function | ||||||||||||||||||||||||||||
Signals |
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Transmembrane Regions |
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Protein Sequence |
>Sodium/calcium exchanger 2 MAPLALVGVTLLLAAPPCSGAATPTPSLPPPPANDSDTSTGGCQGSYRCQPGVLLPVWEP DDPSLGDKAARAVVYFVAMVYMFLGVSIIADRFMAAIEVITSKEKEITITKANGETSVGT VRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFQAGELGPGTIVGSAAFNMFVVIAVC IYVIPAGESRKIKHLRVFFVTASWSIFAYVWLYLILAVFSPGVVQVWEALLTLVFFPVCV VFAWMADKRLLFYKYVYKRYRTDPRSGIIIGAEGDPPKSIELDGTFVGAEAPGELGGLGP GPAEARELDASRREVIQILKDLKQKHPDKDLEQLVGIANYYALLHQQKSRAFYRIQATRL MTGAGNVLRRHAADASRRAAPAEGAGEDEDDGASRIFFEPSLYHCLENCGSVLLSVTCQG GEGNSTFYVDYRTEDGSAKAGSDYEYSEGTLVFKPGETQKELRIGIIDDDIFEEDEHFFV RLLNLRVGDAQGMFEPDGGGRPKGRLVAPLLATVTILDDDHAGIFSFQDRLLHVSECMGT VDVRVVRSSGARGTVRLPYRTVDGTARGGGVHYEDACGELEFGDDETMKTLQVKIVDDEE YEKKDNFFIELGQPQWLKRGISALLLNQGDGDRKLTAEEEEARRIAEMGKPVLGENCRLE VIIEESYDFKNTVDKLIKKTNLALVIGTHSWREQFLEAITVSAGDEEEEEDGSREERLPS CFDYVMHFLTVFWKVLFACVPPTEYCHGWACFGVSILVIGLLTALIGDLASHFGCTVGLK DSVNAVVFVALGTSIPDTFASKVAALQDQCADASIGNVTGSNAVNVFLGLGVAWSVAAVY WAVQGRPFEVRTGTLAFSVTLFTVFAFVGIAVLLYRRRPHIGGELGGPRGPKLATTALFL GLWLLYILFASLEAYCHIRGF |
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External Links | ||||||||||||||||||||||||||||
GenBank ID Protein | 57163987 | |||||||||||||||||||||||||||
UniProtKB/Swiss-Prot ID | Q9UPR5 | |||||||||||||||||||||||||||
UniProtKB/Swiss-Prot Entry Name | NAC2_HUMAN | |||||||||||||||||||||||||||
PDB IDs | Not Available | |||||||||||||||||||||||||||
GenBank Gene ID | NM_015063.2 | |||||||||||||||||||||||||||
GeneCard ID | SLC8A2 | |||||||||||||||||||||||||||
GenAtlas ID | SLC8A2 | |||||||||||||||||||||||||||
HGNC ID | HGNC:11069 | |||||||||||||||||||||||||||
References | ||||||||||||||||||||||||||||
General References |
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