Human Metabolome Database: Showing Protein Thioredoxin reductase 2 isoform 1 variant (HMDBP03310)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 metabolite

Identification

HMDB Protein ID

HMDBP03310

Secondary Accession Numbers

8891

Name

Thioredoxin reductase 2 isoform 1 variant

Synonyms

Not Available

Gene Name

Not Available

Protein Type

Enzyme

Biological Properties

General Function

Involved in oxidoreductase activity

Specific Function

Not Available

Pathways

Not Available

Reactions

Not Available

GO Classification

Component
cell part
intracellular part
cytoplasm
Function
binding
nucleotide binding
catalytic activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
nadp or nadph binding
antioxidant activity
thioredoxin-disulfide reductase activity
oxidoreductase activity
oxidoreductase activity, acting on nadh or nadph
oxidoreductase activity, acting on a sulfur group of donors, nad or nadp as acceptor
fad or fadh2 binding
Process
metabolic process
cellular process
oxidation reduction
cellular homeostasis
cell redox homeostasis

Cellular Location

Not Available

Gene Properties

Chromosome Location

Not Available

Locus

Not Available

SNPs

Not Available

Gene Sequence

>1536 bp
GGAGGGCGCTTCCGGTGGCGGACGCAGGCCGTGGCGGGCGGGGTGCGGGGCGCGGCGCGG
GGCGCAGCAGCAGGTCAGCGGGACTATGATCTCCTGGTGGTCGGCGGGGGATCTGGTGGC
CTGGCTTGTGCCAAGGAGGCCGCTCAGCTGGGAAGGAAGGTGTCCGTGGTGGACTACGTG
GAACCTTCTCCCCAAGGCACCCGGTGGGGCCTCGGCGGCACCTGCGTCAACGTGGGCTGC
ATCCCCAAGAAGCTGATGCACCAGGCGGCACTGCTGGGAGGCCTGATCCAAGATGCCCCC
AACTATGGCTGGGAGGTGGCCCAGCCCGTGCCGCATGACTGGAGGAAGATGGCAGAAGCT
GTTCAAAATCACGTGAAATCCTTGAACTGGGGCCACCGTGTCCAGCTTCAGGACAGAAAA
GTCAAGTACTTTAACATCAAAGCCAGCTTTGTTGACGAGCACACGGTTTGCGGCGTTGCC
AAAGGTGGGAAAGAGATTCTGCTGTCAGCCGATCACATCATCATTGCTACTGGAGGGCGG
CCGAGATACCCCACGCACATCGAAGGTGCCTTGGAATATGGAATCACAAGTGATGACATC
TTCTGGCTGAAGGAATCCCCTGGAAAAACGTTGGTGGTCGGGGCCAGCTATGTGGCCCTG
GAGTGTGCTGGCTTCCTCACCGGGATTGGGCTGGACACCACCATCATGATGCGCAGCATC
CCCCTCCGCGGCTTCGACCAGCAAATGTCCTCCATGGTCATAGAGCACATGGCATCTCAT
GGCACCCGGTTCCTGAGGGGCTGTGCCCCCTCGCGGGTCAGGAGGCTCCCTGATGGCCAG
CTGCAGGTCACCTGGGAGGACAGCACCACCGGCAAGGAGGACACGGGCACCTTTGACACC
GTCCTGTGGGCCATAGGTCGAGTCCCAGACACCAGAAGTCTGAATTTGGAGAAGGCTGGG
GTAGATACTAGCCCCGACACTCAGAAGATCCTGGTGGACTCCCGGGAAGCCACCTCTGTG
CCCCACATCTACGCCATTGGTGACGTGGTGGAGGGGCGGCCTGAGCTGACACCCACAGCG
ATCATGGCCGGGAGGCTCCTGGTGCAGCGGCTCTTCGGCGGGTCCTCAGATCTGATGGAC
TACGACAATGTTCCCACGACCGTCTTCACCCCGCTGGAGTATGGCTGTGTGGGGCTGTCC
GAGGAGGAGGCAGTGGCTCGCCACGGGCAGGAGCATGTTGAGGTCTATCACGCCCATTAT
AAACCACTGGAGTTCACGGTGGCTGGACGAGATGCATCCCAGTGTTATGTAAAGATGGTG
TGCCTGAGGGAGCCCCCACAGCTGGTGCTGGGCCTGCATTTCCTTGGCCCCAACGCAGGC
GAAGTTACTCAAGGATTTGCTCTGGGGATCAAGTGTGGGGCTTCCTATGCGCAGGTGATG
CGGACCGTGGGTATCCATCCCACATGCTCTGAGGAGGTAGTCAAGCTGCGCATCTCCAAG
CGCTCAGGCCTGGACCCCACGGTGACAGGCTGCTGA

Protein Properties

Number of Residues

511

Molecular Weight

55217.7

Theoretical pI

7.37

Pfam Domain Function

Pyr_redox (PF00070 )
Pyr_redox_2 (PF07992 )
Pyr_redox_dim (PF02852 )

Signals

None

Transmembrane Regions

None

Protein Sequence

>Thioredoxin reductase 2 isoform 1 variant
GGRFRWRTQAVAGGVRGAARGAAAGQRDYDLLVVGGGSGGLACAKEAAQLGRKVSVVDYV
EPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEA
VQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGR
PRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSI
PLRGFDQQMSSMVIEHMASHGTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDT
VLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPTA
IMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHY
KPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVM
RTVGIHPTCSEEVVKLRISKRSGLDPTVTGC

External Links

GenBank ID Protein

62089028

UniProtKB/Swiss-Prot ID

Q59ET7

UniProtKB/Swiss-Prot Entry Name

Q59ET7_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AB209724

GeneCard ID