Hmdb loader
Identification
HMDB Protein ID HMDBP06438
Secondary Accession Numbers
  • 12056
Name Putative small intestine sodium-dependent phosphate transport protein
Synonyms
  1. Solute carrier family 17 member 4
Gene Name SLC17A4
Protein Type Unknown
Biological Properties
General Function Involved in transmembrane transport
Specific Function May be involved in actively transporting phosphate into cells via Na(+) cotransport (By similarity).
Pathways Not Available
Reactions Not Available
GO Classification
Biological Process
phosphate-containing compound metabolic process
Cellular Component
integral to plasma membrane
Molecular Function
sodium:phosphate symporter activity
Process
establishment of localization
transport
transmembrane transport
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein (Potential)
Gene Properties
Chromosome Location 6
Locus 6p22.2
SNPs SLC17A4
Gene Sequence
>1494 bp
ATGTCTACCGGACCAGATGTCAAGGCTACAGTGGGGGACATTTCCAGTGATGGCAATTTA
AACGTGGCTCAAGAGGAATGCTCCAGGAAAGGTTTTTGTTCAGTCCGACATGGGCTGGCC
CTCATCTTGCAGCTCTGTAATTTTTCAATTTACACCCAACAAATGAACTTGAGCATTGCC
ATTCCAGCTATGGTGAACAACACAGCCCCACCTAGCCAGCCCAATGCCTCCACAGAACGG
CCCTCCACTGACTCCCAGGGCTACTGGAATGAAACTCTAAAAGAATTTAAAGCAATGGCC
CCTGCATATGACTGGAGTCCTGAAATCCAGGGAATCATCCTCAGCTCCCTCAACTATGGC
TCATTCTTGGCTCCAATCCCCAGTGGCTATGTGGCTGGAATATTTGGAGCCAAGTATGTG
GTTGGTGCTGGCTTGTTTATTTCCTCATTCCTGACCCTCTTCATTCCACTGGCAGCTAAT
GCGGGAGTGGCCTTGCTCATTGTCCTCCGGATTGTACAAGGCATAGCCCAGGTTATGGTA
TTAACTGGTCAGTATTCAATTTGGGTCAAATGGGCTCCCCCACTGGAAAGGAGTCAACTC
ACCACCATTGCTGGATCAGGGTCAATGCTGGGGTCCTTCATTGTTCTACTTGCTGGTGGT
CTCCTCTGCCAGACCATAGGATGGCCTTACGTCTTCTATATCTTTGGAGGAATTGGCTGT
GCTTGTTGTCCTCTCTGGTTTCCTCTCATTTATGATGATCCTGTGAATCATCCCTTTATC
AGTGCTGGTGAGAAGAGATACATTGTGTGTTCATTGGCTCAGCAGGACTGTTCACCAGGC
TGGTCTCTTCCCATTAGGGCTATGATCAAATCCTTACCACTCTGGGCCATTTTAGTCTCT
TATTTCTGTGAATACTGGCTTTTTTATACCATTATGGCGTACACACCAACGTACATCAGC
TCGGTACTTCAAGCCAACCTCAGAGATAGTGGGATCCTGTCTGCCTTGCCGTTTGTTGTT
GGATGTATCTGCATTATCCTTGGAGGTCTACTGGCAGACTTTCTTCTCTCCAGAAAAATC
CTCAGACTCATCACCATCAGGAAACTCTTCACTGCCATTGGGGTTCTCTTCCCATCCGTG
ATCCTCGTGTCCCTGCCCTGGGTCAGATCCAGCCACAGCATGACCATGACCTTCTTGGTG
CTGTCTTCTGCCATCAGCAGCTTCTGTGAATCAGGAGCCCTTGTTAACTTCTTGGATATT
GCTCCTCGGTACACTGGCTTTCTCAAAGGACTATTGCAAGTCTTTGCACACATAGCTGGA
GCCATCTCTCCTACTGCTGCTGGATTTTTCATCAGTCAGGATTCAGAGTTTGGTTGGAGA
AATGTCTTCTTGCTTTCAGCTGCTGTTAACATATCGGGCCTGGTTTTCTACCTCATCTTT
GGCCGAGCAGATGTGCAGGACTGGGCTAAGGAGCAGACATTCACCCACCTCTGA
Protein Properties
Number of Residues 497
Molecular Weight 54054.61
Theoretical pI 7.49
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Putative small intestine sodium-dependent phosphate transport protein
MSTGPDVKATVGDISSDGNLNVAQEECSRKGFCSVRHGLALILQLCNFSIYTQQMNLSIA
IPAMVNNTAPPSQPNASTERPSTDSQGYWNETLKEFKAMAPAYDWSPEIQGIILSSLNYG
SFLAPIPSGYVAGIFGAKYVVGAGLFISSFLTLFIPLAANAGVALLIVLRIVQGIAQVMV
LTGQYSIWVKWAPPLERSQLTTIAGSGSMLGSFIVLLAGGLLCQTIGWPYVFYIFGGIGC
ACCPLWFPLIYDDPVNHPFISAGEKRYIVCSLAQQDCSPGWSLPIRAMIKSLPLWAILVS
YFCEYWLFYTIMAYTPTYISSVLQANLRDSGILSALPFVVGCICIILGGLLADFLLSRKI
LRLITIRKLFTAIGVLFPSVILVSLPWVRSSHSMTMTFLVLSSAISSFCESGALVNFLDI
APRYTGFLKGLLQVFAHIAGAISPTAAGFFISQDSEFGWRNVFLLSAAVNISGLVFYLIF
GRADVQDWAKEQTFTHL
GenBank ID Protein 4587207
UniProtKB/Swiss-Prot ID Q9Y2C5
UniProtKB/Swiss-Prot Entry Name S17A4_HUMAN
PDB IDs Not Available
GenBank Gene ID AB020527
GeneCard ID SLC17A4
GenAtlas ID SLC17A4
HGNC ID HGNC:10932
References
General References
  1. Mungall AJ, Palmer SA, Sims SK, Edwards CA, Ashurst JL, Wilming L, Jones MC, Horton R, Hunt SE, Scott CE, Gilbert JG, Clamp ME, Bethel G, Milne S, Ainscough R, Almeida JP, Ambrose KD, Andrews TD, Ashwell RI, Babbage AK, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beare DM, Beasley H, Beasley O, Bird CP, Blakey S, Bray-Allen S, Brook J, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Clark SY, Clark G, Clee CM, Clegg S, Cobley V, Collier RE, Collins JE, Colman LK, Corby NR, Coville GJ, Culley KM, Dhami P, Davies J, Dunn M, Earthrowl ME, Ellington AE, Evans KA, Faulkner L, Francis MD, Frankish A, Frankland J, French L, Garner P, Garnett J, Ghori MJ, Gilby LM, Gillson CJ, Glithero RJ, Grafham DV, Grant M, Gribble S, Griffiths C, Griffiths M, Hall R, Halls KS, Hammond S, Harley JL, Hart EA, Heath PD, Heathcott R, Holmes SJ, Howden PJ, Howe KL, Howell GR, Huckle E, Humphray SJ, Humphries MD, Hunt AR, Johnson CM, Joy AA, Kay M, Keenan SJ, Kimberley AM, King A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd CR, Lloyd DM, Loveland JE, Lovell J, Martin S, Mashreghi-Mohammadi M, Maslen GL, Matthews L, McCann OT, McLaren SJ, McLay K, McMurray A, Moore MJ, Mullikin JC, Niblett D, Nickerson T, Novik KL, Oliver K, Overton-Larty EK, Parker A, Patel R, Pearce AV, Peck AI, Phillimore B, Phillips S, Plumb RW, Porter KM, Ramsey Y, Ranby SA, Rice CM, Ross MT, Searle SM, Sehra HK, Sheridan E, Skuce CD, Smith S, Smith M, Spraggon L, Squares SL, Steward CA, Sycamore N, Tamlyn-Hall G, Tester J, Theaker AJ, Thomas DW, Thorpe A, Tracey A, Tromans A, Tubby B, Wall M, Wallis JM, West AP, White SS, Whitehead SL, Whittaker H, Wild A, Willey DJ, Wilmer TE, Wood JM, Wray PW, Wyatt JC, Young L, Younger RM, Bentley DR, Coulson A, Durbin R, Hubbard T, Sulston JE, Dunham I, Rogers J, Beck S: The DNA sequence and analysis of human chromosome 6. Nature. 2003 Oct 23;425(6960):805-11. [PubMed:14574404 ]
  2. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]
  3. Shibui A, Tsunoda T, Seki N, Suzuki Y, Sugane K, Sugano S: Isolation and chromosomal mapping of a novel human gene showing homology to Na+/PO4 cotransporter. J Hum Genet. 1999;44(3):190-2. [PubMed:10319585 ]