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Identification
HMDB Protein ID HMDBP07322
Secondary Accession Numbers
  • 12944
Name Probable lipid phosphate phosphatase PPAPDC3
Synonyms
  1. Phosphatidic acid phosphatase type 2 domain-containing protein 3
Gene Name PPAPDC3
Protein Type Enzyme
Biological Properties
General Function Involved in catalytic activity
Specific Function Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity
Pathways Not Available
Reactions Not Available
GO Classification
Component
membrane
cell part
Function
catalytic activity
Cellular Location
  1. Membrane
  2. Endoplasmic reticulum membrane
  3. Multi-pass membrane protein
  4. Nucleus envelope
Gene Properties
Chromosome Location Chromosome:9
Locus 9q34.13
SNPs PPAPDC3
Gene Sequence
>816 bp
ATGCCAGCTTCCCAGAGCCGGGCCCGTGCCCGGGACCGCAACAACGTCCTCAACCGGGCT
GAGTTCCTGTCCCTGAACCAGCCCCCCAAGGGGGGCCCGGAGCCCCGCAGCTCGGGCAGA
AAGGCCTCGGGCCCATCAGCACAGCCCCCACCTGCTGGTGACGGGGCCAGAGAGCGACGC
CAGTCACAGCAGCTGCCAGAGGAGGACTGCATGCAGCTGAACCCCTCCTTCAAGGGCATC
GCCTTCAACTCCCTGCTGGCCATCGATATCTGTATGTCCAAGCGGCTGGGGGTGTGCGCT
GGCCGGGCGGCGTCCTGGGCCAGTGCCCGCTCCATGGTCAAGCTCATCGGCATCACGGGC
CACGGCATCCCCTGGATCGGAGGCACCATCCTCTGCCTGGTGAAGAGCAGCACACTGGCC
GGCCAGGAGGTGCTCATGAATCTGCTCCTGGCCCTGCTCCTGGACATCATGACGGTGGCC
GGCGTGCAGAAGCTCATCAAGCGGCGCGGCCCGTACGAGACGAGCCCCAGCCTCCTGGAC
TACCTCACCATGGACATCTACGCCTTCCCGGCCGGGCACGCCAGCCGCGCCGCCATGGTG
TCCAAGTACTTCCTCAGCCACCTGGTGCTGGCGGTGCCCCTGCGTGTGCTGCTGGTGCTC
TGGGCCCTCTGCGTGGGCCTGTCCCGCGTGATGATCGGCCGCCACCACGTCACGGACGTC
CTCTCCGGCTTTGTCATCGGCTACCTCCAGTTCCGTCTGGTGGAGCTGGTCTGGATGCCC
TCCAGCACCTGCCAGATGCTCATCTCTGCCTGGTGA
Protein Properties
Number of Residues 271
Molecular Weight 29447.3
Theoretical pI 10.5
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • 113-133
  • 142-162
  • 203-223
  • 240-260
Protein Sequence
>Probable lipid phosphate phosphatase PPAPDC3
MPASQSRARARDRNNVLNRAEFLSLNQPPKGGPEPRSSGRKASGPSAQPPPAGDGARERR
QSQQLPEEDCMQLNPSFKGIAFNSLLAIDICMSKRLGVCAGRAASWASARSMVKLIGITG
HGIPWIGGTILCLVKSSTLAGQEVLMNLLLALLLDIMTVAGVQKLIKRRGPYETSPSLLD
YLTMDIYAFPAGHASRAAMVSKFFLSHLVLAVPLRVLLVLWALCVGLSRVMIGRHHVTDV
LSGFVIGYLQFRLVELVWMPSSTCQMLISAW
GenBank ID Protein 14042336
UniProtKB/Swiss-Prot ID Q8NBV4
UniProtKB/Swiss-Prot Entry Name PPAC3_HUMAN
PDB IDs Not Available
GenBank Gene ID AK027568
GeneCard ID PPAPDC3
GenAtlas ID PPAPDC3
HGNC ID HGNC:28174
References
General References
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