Showing Protein Clathrin heavy chain 2 (HMDBP07613)
Identification | |||||||||||||||||||
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HMDB Protein ID | HMDBP07613 | ||||||||||||||||||
Secondary Accession Numbers |
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Name | Clathrin heavy chain 2 | ||||||||||||||||||
Synonyms |
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Gene Name | CLTCL1 | ||||||||||||||||||
Protein Type | Unknown | ||||||||||||||||||
Biological Properties | |||||||||||||||||||
General Function | Involved in binding | ||||||||||||||||||
Specific Function | Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network | ||||||||||||||||||
Pathways | Not Available | ||||||||||||||||||
Reactions | Not Available | ||||||||||||||||||
GO Classification |
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Cellular Location |
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Gene Properties | |||||||||||||||||||
Chromosome Location | Chromosome:2 | ||||||||||||||||||
Locus | 22q11.2|22q11.21 | ||||||||||||||||||
SNPs | CLTCL1 | ||||||||||||||||||
Gene Sequence |
>4923 bp ATGGCGCAGATCCTCCCTGTTCGCTTTCAGGAGCACTTCCAGCTCCAAAACCTTGGAATT AATCCAGCTAACATTGGATTCAGCACACTGACCATGGAATCTGACAAGTTCATATGTATC CGAGAGAAAGTTGGTGAGCAGGCACAGGTCACGATCATTGACATGAGTGACCCAATGGCT CCGATCCGACGGCCTATCTCTGCAGAGAGTGCCATCATGAATCCAGCCTCTAAGGTGATA GCTCTGAAAGCTGGGAAGACACTTCAGATCTTTAATATTGAGATGAAGAGTAAAATGAAG GCTCATACTATGGCAGAAGAAGTGATTTTCTGGAAATGGGTTTCTGTGAACACTGTTGCC TTGGTGACCGAGACCGCGGTCTACCACTGGAGCATGGAAGGTGACTCCCAGCCCATGAAG ATGTTTGATAGACATACCAGTCTGGTGGGCTGCCAGGTGATTCACTACCGGACTGATGAG TACCAGAAGTGGCTGCTGCTCGTAGGCATCTCGGCTCAGCAAAACCGTGTGGTTGGAGCA ATGCAGCTCTACTCTGTGGATAGGAAGGTTTCACAACCCATAGAAGGCCATGCTGCGGCT TTTGCAGAGTTCAAGATGGAGGGGAATGCCAAGCCTGCCACCCTTTTCTGCTTTGCTGTA CGTAATCCCACAGGAGGCAAGTTGCACATCATTGAAGTTGGACAGCCTGCAGCGGGAAAC CAACCTTTTGTAAAGAAAGCAGTAGATGTGTTTTTTCCTCCAGAGGCACAGAATGATTTT CCAGTGGCTATGCAGATTGGAGCTAAACATGGTGTTATTTACTTGATCACAAAGTATGGC TATCTTCATCTGTACGACCTAGAGTCTGGCGTGTGCATCTGCATGAACCGTATTAGTGCT GACACAATATTTGTCACTGCTCCACACAAACCAACCTCTGGAATTATTGGTGTCAACAAA AAGGGACAGGTACTGTCAGTTTGTGTTGAGGAAGATAACATTGTGAATTATGCAACCAAC GTGCTTCAGAATCCAGACCTTGGTCTGCGTTTGGCCGTTCGTAGTAACCTGGCTGGGGCA GAGAAGTTGTTTGTGAGAAAATTCAATACCCTCTTTGCACAGGGCAGCTATGCTGAAGCC GCCAAAGTTGCAGCGTCTGCACCAAAGGGAATCCTGCGTACCAGAGAGACGGTCCAGAAA TTCCAGAGTATACCCGCTCAGTCTGGCCAGGCTTCTCCATTGCTGCAGTACTTCGGAATC CTGCTCGACCAGGGTCAGCTCAATAAACTTGAATCCTTAGAACTTTGCCATCTGGTTCTT CAGCAGGGGCGTAAGCAACTCCTAGAGAAGTGGCTGAAAGAAGATAAGCTGGAGTGCTCA GAGGAGCTCGGAGACTTGGTCAAAACCACTGACCCCATGCTCGCTCTGAGTGTGTACCTT CGGGCAAATGTGCCAAGCAAAGTGATCCAGTGTTTTGCAGAAACAGGCCAATTCCAGAAA ATTGTGCTCTATGCCAAAAAGGTTGGGTACACCCCAGACTGGATCTTTCTGCTGAGGGGT GTAATGAAGATCAGTCCGGAACAGGGCCTGCAGTTTTCTCGAATGCTAGTGCAGGACGAG GAGCCGCTGGCCAACATTAGCCAGATTGTGGACATTTTCATGGAAAACAGTTTAATTCAG CAGTGTACTTCCTTCTTATTGGATGCCTTGAAGAATAATCGCCCAGCTGAGGGACTCCTG CAGACATGGCTGTTGGAGATGAACCTTGTTCATGCACCCCAGGTTGCAGATGCCATCCTT GGAAATAAAATGTTTACTCATTACGACCGGGCCCACATTGCCCAGCTCTGTGAGAAGGCA GGCCTCCTGCAGCAAGCACTGGAGCACTACACCGACCTCTATGACATCAAGAGGGCTGTG GTCCACACTCACCTCCTCAATCCCGAGTGGCTTGTCAATTTCTTTGGCTCCTTATCGGTG GAGGATTCTGTGGAGTGTCTGCATGCCATGCTGTCTGCTAACATCAGACAGAACCTTCAG CTGTGTGTGCAGGTGGCCTCTAAGTACCACGAGCAGCTGGGCACGCAGGCCCTGGTGGAG CTCTTTGAATCCTTCAAGAGTTACAAAGGCCTCTTCTACTTCCTGGGCTCAATCGTGAAC TTCAGCCAAGACCCAGATGTGCATCTGAAATACATTCAGGCTGCCTGTAAGACAGGGCAG ATCAAGGAGGTGGAGAGGATATGCCGAGAGAGCAGCTGCTACAACCCAGAGCGTGTGAAG AACTTCCTGAAGGAGGCCAAGCTCACAGACCAGCTTCCCCTCATCATCGTGTGTGATCGT TTTGGCTTTGTCCATGACCTTGTCCTATATTTATACCGCAACAACCTGCAGAGGTACATT GAGATCTACGTGCAGAAGGTCAACCCTAGCCGGACCCCAGCTGTGATTGGAGGGCTGCTT GATGTGGATTGTTCTGAGGAAGTGATTAAACACTTAATCATGGCAGTGAGAGGACAGTTC TCTACTGATGAGTTGGTGGCTGAAGTAGAAAAAAGAAATAGGCTCAAGCTGCTGCTTCCC TGGCTGGAGTCCCAGATTCAGGAAGGCTGTGAGGAGCCTGCCACTCACAATGCACTGGCT AAAATCTACATCGACAGCAACAACAGCCCCGAGTGCTTCCTGAGAGAGAATGCCTACTAT GACAGCAGCGTGGTGGGCCGCTACTGTGAGAAGCGAGACCCCCATCTGGCCTGTGTTGCC TATGAGCGGGGGCAGTGTGACCTTGAGCTCATCAAGGTGTGCAATGAGAATTCTCTGTTC AAAAGCGAGGCCCGCTACCTGGTATGCAGAAAGGATCCGGAGCTCTGGGCTCACGTCCTT GAGGAGACCAACCCATCCAGGAGACAGCTAATTGACCAGGTGGTACAGACAGCATTGTCA GAAACACGGGATCCTGAAGAGATTTCGGTCACTGTCAAAGCCTTTATGACAGCCGACCTG CCTAATGAACTGATTGAACTGCTGGAGAAGATAGTTCTGGATAACTCTGTCTTCAGCGAG CACAGGAATCTACAGAATCTGTTGATCCTGACTGCCATCAAGGCAGACCGCACACGGGTC ATGGAGTACATCAGCCGCCTGGACAACTATGACGCACTGGACATCGCGAGCATCGCTGTC AGCAGCGCACTGTATGAGGAGGCCTTCACCGTTTTCCACAAGTTTGATATGAATGCCTCA GCAATCCAGGTCCTGATCGAGCACATTGGAAACCTGGACCGGGCATATGAGTTTGCGGAG AGATGCAATGAGCCTGCTGTGTGGAGTCAGCTGGCCCAAGCCCAGCTCCAGAAAGATTTG GTGAAGGAAGCCATCAACTCCTATATCAGAGGGGACGACCCTTCCTCTTACCTGGAAGTT GTTCAGTCAGCCAGCAGGAGCAACAACTGGGAGGATCTAGTTAAATTTCTGCAGATGGCC AGGAAAAAGGGCCGTGAGTCCTATATAGAGACTGAACTTATTTTTGCCTTGGCTAAAACC AGCCGTGTTTCTGAGCTAGAAGATTTTATTAATGGACCCAACAATGCCCACATCCAGCAG GTTGGAGACCGCTGTTACGAGGAGGGAATGTACGAGGCTGCCAAGCTGCTCTATAGCAAT GTTTCTAACTTTGCCCGCCTGGCTTCCACCTTGGTTCACCTCGGTGAGTATCAGGCAGCA GTGGACAACAGCCGCAAGGCCAGCAGCACCCGGACGTGGAAGGAGGTGTGCTTTGCCTGC ATGGATGGACAAGAGTTCCGCTTCGCACAGCTGTGTGGTCTTCACATCGTCATTCATGCA GATGAGCTGGAGGAGCTGATGTGCTATTACCAGGATCGTGGCTACTTTGAGGAGCTGATC TTGCTGTTGGAAGCGGCCCTGGGCCTGGAGCGGGCCCACATGGGCATGTTCACTGAGCTG GCCATCCTCTACTCCAAATTCAAGCCACAGAAGATGCTGGAGCATCTGGAGCTTTTCTGG TCCCGTGTCAACATCCCAAAGGTGCTGAGGGCTGCAGAGCAGGCACACCTGTGGGCTGAG CTGGTGTTCCTCTATGACAAGTACGAGGAGTATGACAATGCTGTGCTCACCATGATGAGC CACCCCACTGAGGCCTGGAAGGAGGGTCAGTTCAAGGACATCATTACCAAGGTTGCCAAC GTCGAGCTCTGTTACAGAGCCCTGCAGTTCTATTTGGATTACAAACCACTGCTCATCAAT GACCTGCTGCTGGTGCTTTCACCCCGGCTGGACCACACCTGGACAGTCAGTTTCTTTTCA AAGGCAGGTCAGCTGCCCCTGGTGAAGCCTTACCTGCGGTCAGTCCAGAGCCACAACAAC AAGAGTGTGAATGAGGCACTCAACCACCTGCTGACAGAGGAGGAGGACTATCAGGGCTTA AGGGCATCTATCGATGCCTATGACAACTTTGACAACATCAGCCTGGCTCAGCAGCTGGAG AAGCATCAGCTGATGGAGTTCAGGTGCATTGCGGCCTATCTGTACAAGGGCAATAACTGG TGGGCCCAGAGCGTGGAGCTCTGCAAGAAGGATCATCTCTACAAGGATGCCATGCAGCAT GCTGCAGAGTCGCGGGATGCTGAGCTGGCCCAGAAGTTGCTGCAGTGGTTCCTGGAGGAA GGCAAGAGGGAGTGCTTCGCAGCTTGTCTCTTCACCTGCTATGACCTGCTTCGCCCAGAC ATGGTGCTTGAGCTGGCCTGGAGGCACAACCTCGTGGACTTGGCCATGCCCTACTTCATC CAGGTGATGAGGGAGTACCTGAGCAAGGTGGACAAACTGGATGCCTTGGAGAGTCTGCGC AAGCAAGAGGAGCATGTGACAGAGCCTGCCCCTCTCGTGTTTGATTTTGATGGGCATGAA TGA |
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Protein Properties | |||||||||||||||||||
Number of Residues | 1640 | ||||||||||||||||||
Molecular Weight | 187028.2 | ||||||||||||||||||
Theoretical pI | 5.67 | ||||||||||||||||||
Pfam Domain Function | |||||||||||||||||||
Signals |
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Transmembrane Regions |
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Protein Sequence |
>Clathrin heavy chain 2 MAQILPVRFQEHFQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDMSDPMA PIRRPISAESAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVA LVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGA MQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVGQPAAGN QPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESGVCICMNRISA DTIFVTAPHKPTSGIIGVNKKGQVLSVCVEEDNIVNYATNVLQNPDLGLRLAVRSNLAGA EKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGI LLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYL RANVPSKVIQCFAETGQFQKIVLYAKKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDE EPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQVADAIL GNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSV EDSVECLHAMLSANIRQNLQLCVQVASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVN FSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLIIVCDR FGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQF STDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSPECFLRENAYY DSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPELWAHVL EETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSE HRNLQNLLILTAIKADRTRVMEYISRLDNYDALDIASIAVSSALYEEAFTVFHKFDMNAS AIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPSSYLEV VQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFINGPNNAHIQQ VGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFAC MDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGMFTEL AILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMS HPTEAWKEGQFKDIITKVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFS KAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQGLRASIDAYDNFDNISLAQQLE KHQLMEFRCIAAYLYKGNNWWAQSVELCKKDHLYKDAMQHAAESRDAELAQKLLQWFLEE GKRECFAACLFTCYDLLRPDMVLELAWRHNLVDLAMPYFIQVMREYLSKVDKLDALESLR KQEEHVTEPAPLVFDFDGHE |
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External Links | |||||||||||||||||||
GenBank ID Protein | 242246985 | ||||||||||||||||||
UniProtKB/Swiss-Prot ID | P53675 | ||||||||||||||||||
UniProtKB/Swiss-Prot Entry Name | CLH2_HUMAN | ||||||||||||||||||
PDB IDs | Not Available | ||||||||||||||||||
GenBank Gene ID | NM_007098.3 | ||||||||||||||||||
GeneCard ID | CLTCL1 | ||||||||||||||||||
GenAtlas ID | CLTCL1 | ||||||||||||||||||
HGNC ID | HGNC:2093 | ||||||||||||||||||
References | |||||||||||||||||||
General References |
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