Hmdb loader
Identification
HMDB Protein ID HMDBP07621
Secondary Accession Numbers
  • 13330
Name Copine-3
Synonyms
  1. Copine III
Gene Name CPNE3
Protein Type Unknown
Biological Properties
General Function Involved in calcium-dependent phospholipid binding
Specific Function May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location Chromosome:8
Locus 8q21.3
SNPs CPNE3
Gene Sequence
>1614 bp
ATGGCTGCCCAGTGTGTCACAAAGGTGGCGCTGAATGTTTCCTGTGCCAATCTTTTGGAT
AAAGATATAGGGTCAAAGTCAGACCCTTTATGTGTGTTGTTTTTGAATACAAGTGGTCAA
CAGTGGTATGAGGTTGAGCGCACAGAAAGGATTAAGAATTGCTTGAATCCCCAATTTTCC
AAGACATTTATTATTGATTACTACTTTGAAGTGGTTCAGAAATTGAAATTTGGGGTTTAT
GACATCGACAACAAAACTATTGAGCTGAGTGATGATGACTTCTTAGGGGAATGTGAATGT
ACCCTTGGACAAATTGTTTCCAGCAAGAAGCTAACTCGACCACTGGTGATGAAAACTGGC
AGACCTGCAGGAAAAGGGAGCATTACGATTTCAGCTGAAGAAATAAAAGATAATAGAGTG
GTCTTGTTTGAAATGGAAGCCAGAAAACTGGATAATAAGGATCTATTTGGAAAGTCAGAC
CCATACCTGGAATTCCACAAGCAGACATCTGATGGAAACTGGCTAATGGTTCATCGGACA
GAGGTTGTTAAAAACAACTTGAATCCTGTTTGGAGGCCTTTCAAGATCTCTCTTAACTCA
CTGTGTTACGGAGATATGGACAAAACCATTAAGGTGGAGTGTTATGATTATGACAATGAT
GGGTCACATGATCTCATTGGAACATTTCAGACCACCATGACAAAACTGAAAGAAGCCTCC
AGAAGCTCACCTGTTGAATTTGAATGCATAAATGAGAAAAAAAGGCAAAAGAAAAAAAGC
TACAAGAATTCAGGTGTTATCAGTGTGAAACAGTGTGAGATTACAGTAGAATGCACATTC
CTTGACTATATAATGGGAGGATGTCAGCTGAATTTTACTGTGGGAGTGGACTTCACTGGC
TCCAATGGTGACCCAAGGTCTCCAGACTCCCTTCATTACATCAGCCCCAATGGCGTTAAT
GAGTATTTGACTGCTCTCTGGTCTGTGGGACTGGTCATTCAAGATTATGATGCTGATAAG
ATGTTTCCAGCTTTTGGTTTTGGCGCTCAGATACCTCCTCAGTGGCAGGTATCACATGAA
TTTCCAATGAACTTCAACCCATCCAATCCCTACTGCAATGGAATCCAAGGCATTGTAGAG
GCGTATCGGTCTTGTCTTCCTCAGATAAAACTCTATGGACCAACTAATTTTTCTCCAATC
ATAAATCACGTGGCCAGGTTTGCTGCTGCAGCCACGCAACAGCAGACAGCTTCTCAATAT
TTTGTGCTTTTGATTATTACTGATGGTGTGATCACAGACCTTGATGAAACCAGACAAGCT
ATAGTTAATGCCTCCAGGCTGCCTATGTCCATCATAATTGTTGGAGTTGGAGGTGCTGAC
TTCAGCGCCATGGAGTTTCTGGATGGTGATGGTGGAAGTCTCCGCTCCCCATTGGGCGAA
GTGGCCATCAGAGATATTGTCCAGTTTGTGCCTTTCAGACAGTTCCAGAATGCTCCAAAA
GAAGCACTTGCTCAGTGTGTCTTGGCAGAGATTCCCCAGCAGGTGGTGGGCTACTTCAAT
ACATACAAACTCCTTCCTCCCAAGAACCCAGCCACGAAACAACAGAAGCAGTGA
Protein Properties
Number of Residues 537
Molecular Weight 60130.2
Theoretical pI 5.57
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Copine-3
MAAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFS
KTFIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTG
RPAGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRT
EVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEAS
RSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTG
SNGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHE
FPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQY
FVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGE
VAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLPPKNPATKQQKQ
GenBank ID Protein 4503015
UniProtKB/Swiss-Prot ID O75131
UniProtKB/Swiss-Prot Entry Name CPNE3_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_003909.3
GeneCard ID CPNE3
GenAtlas ID CPNE3
HGNC ID HGNC:2316
References
General References
  1. Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S: Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 2004 Jan;36(1):40-5. Epub 2003 Dec 21. [PubMed:14702039 ]
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  3. Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. Anal Chem. 2009 Jun 1;81(11):4493-501. doi: 10.1021/ac9004309. [PubMed:19413330 ]
  4. Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 1998 Jun 30;5(3):169-76. [PubMed:9734811 ]
  5. Caudell EG, Caudell JJ, Tang CH, Yu TK, Frederick MJ, Grimm EA: Characterization of human copine III as a phosphoprotein with associated kinase activity. Biochemistry. 2000 Oct 24;39(42):13034-43. [PubMed:11041869 ]