Hmdb loader
Identification
HMDB Protein ID HMDBP07665
Secondary Accession Numbers
  • 13374
Name EF-hand domain-containing family member A2
Synonyms Not Available
Gene Name EFHA2
Protein Type Unknown
Biological Properties
General Function Involved in calcium ion binding
Specific Function Not Available
Pathways Not Available
Reactions Not Available
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Cellular Location
  1. Membrane
  2. Single-pass membrane protein (Potential)
Gene Properties
Chromosome Location Chromosome:8
Locus 8p22
SNPs EFHA2
Gene Sequence
>1593 bp
ATGGCTGCGCTGCGAAGGCTCTTGTGGCCGCCACCCCGGGTGTCTCCTCCACTCTGCGCT
CACCAGCCCCTCCTTGGGCCGTGGGGGCGGCCTGCGGTGACCACCCTGGGCCTTCCTGGC
CGGCCCTTCTCCTCCCGAGAGGATGAGGAGAGGGCTGTGGCGGAGGCGGCATGGAGGCGG
CGGCGGCGCTGGGGGGAGCTGAGCGTGGCGGCGGCGGCCGGCGGGGGGCTGGTCGGCCTG
GTATGCTACCAGCTGTACGGGGACCCCAGGGCCGGCTCGCCGGCGACCGGGCGACCCTCA
AAGAGCGCGGCCACGGAGCCCGAGGACCCGCCCCGCGGCCGGGGGATGCTGCCCATCCCA
GTGGCGGCTGCCAAGGAGACGGTTGCTATTGGCAGAACAGACATTGAAGACTTAGACCTT
TATGCCACATCTCGGGAGAGGCGATTTCGTTTATTTGCTTCTATAGAATGTGAAGGGCAG
TTATTCATGACTCCGTATGATTTTATTTTGGCTGTTACAACAGATGAGCCCAAAGTTGCC
AAAACTTGGAAGTCACTTTCCAAACAGGAATTAAATCAAATGCTCGCAGAAACACCACCA
GTTTGGAAAGGCTCATCGAAGCTATTTCGAAATCTTAAAGAAAAAGGTGTGATTTCTTAC
ACAGAATATCTTTTTCTTTTATGTATTTTAACAAAGCCACATGCAGGGTTCAGAATAGCT
TTCAACATGTTTGACACTGATGGCAATGAGATGGTGGATAAAAAAGAGTTTTTGGTGCTT
CAAGAGATATTCAGGAAAAAAAATGAAAAGAGAGAAATTAAAGGAGATGAAGAAAAGCGT
GCAATGCTGCGTCTTCAACTTTATGGATACCATTCTCCTACTAATAGTGTACTTAAAACA
GATGCTGAGGAACTTGTCTCCAGAAGCTATTGGGATACACTGAGACGTAACACAAGCCAA
GCACTGTTTTCAGACCTCGCAGAGCGTGCTGATGACATCACAAGTTTAGTAACAGATACT
ACACTTCTTGTACACTTTTTTGGAAAGAAAGGAAAAGCTGAGCTCAACTTTGAAGATTTT
TATAGATTCATGGATAATCTCCAAACAGAAGTTCTAGAAATAGAATTCCTTTCCTACTCA
AATGGAATGAATACCATCAGTGAAGAAGATTTTGCTCATATTCTTTTACGATATACAAAT
GTGGAAAATACATCAGTATTTTTAGAAAATGTGCGTTACAGTATACCTGAAGAAAAGGGC
ATCACATTTGATGAATTCAGGTCATTTTTCCAGTTTTTAAACAACCTAGAAGACTTTGCA
ATAGCCCTGAATATGTATAACTTTGCAAGTCGTTCTATAGGGCAAGATGAATTTAAACGT
GCCGTCTATGTAGCTACTGGACTCAAATTTTCACCACATTTAGTGAACACTGTCTTCAAG
ATTTTTGATGTTGACAAAGATGATCAATTAAGTTATAAAGAATTTATTGGAATTATGAAA
GACAGACTCCATAGAGGATTCCGGGGTTATAAAACAGTCCAGAAGTACCCCACTTTCAAA
TCCTGCCTGAAGAAAGAACTTCACAGCAGATAA
Protein Properties
Number of Residues 530
Molecular Weight 60710.8
Theoretical pI 8.4
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 67-83
Protein Sequence
>EF-hand domain-containing family member A2
MAALRRLLWPPPRVSPPLCAHQPLLGPWGRPAVTTLGLPGRPFSSREDEERAVAEAAWRR
RRRWGELSVAAAAGGGLVGLVCYQLYGDPRAGSPATGRPSKSAATEPEDPPRGRGMLPIP
VAAAKETVAIGRTDIEDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKVA
KTWKSLSKQELNQMLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIA
FNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKT
DAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTLLVHFFGKKGKAELNFEDF
YRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKG
ITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSPHLVNTVFK
IFDVDKDDQLSYKEFIGIMKDRLHRGFRGYKTVQKYPTFKSCLKKELHSR
GenBank ID Protein 32171205
UniProtKB/Swiss-Prot ID Q86XE3
UniProtKB/Swiss-Prot Entry Name EFHA2_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_181723.2
GeneCard ID EFHA2
GenAtlas ID EFHA2
HGNC ID HGNC:27820
References
General References
  1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]