Hmdb loader
Identification
HMDB Protein ID HMDBP07692
Secondary Accession Numbers
  • 13401
Name FRAS1-related extracellular matrix protein 2
Synonyms
  1. ECM3 homolog
Gene Name FREM2
Protein Type Unknown
Biological Properties
General Function Involved in calcium ion binding
Specific Function Extracellular matrix protein required for maintenance of the integrity of the skin epithelium and for maintenance of renal epithelia. May be required for epidermal adhesion
Pathways Not Available
Reactions Not Available
GO Classification
Component
membrane
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
cell adhesion
cellular process
cell-cell adhesion
homophilic cell adhesion
cell communication
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
  3. Extracellular side (Potential)
Gene Properties
Chromosome Location Chromosome:1
Locus 13q13.3
SNPs FREM2
Gene Sequence
>9510 bp
ATGCACTCAGCCGGGACTCCCGGGTTATCCTCGCGCCGGACAGGCAACTCCACCAGCTTT
CAACCAGGACCGCCACCGCCGCCCCGGCTGCTGCTGCTGCTGCTGCTTCTCCTGTCACTG
GTAAGCCGCGTCCCGGCACAGCCCGCTGCCTTCGGCAGGGCGTTGCTGTCCCCTGGTCTC
GCGGGGGCTGCAGGGGTCCCTGCTGAGGAGGCCATAGTGCTGGCGAACCGCGGACTCCGG
GTGCCTTTCGGCCGTGAAGTCTGGCTGGATCCCCTGCATGACCTGGTGTTGCAGGTGCAG
CCCGGGGACCGCTGCGCGGTTTCGGTACTAGACAACGACGCACTGGCCCAGCGACCGGGC
CGCCTGAGTCCCAAGCGCTTCCCGTGCGACTTTGGCCCTGGCGAGGTGCGCTACTCTCAC
CTGGGCGCGCGCAGCCCGTCTCGGGACCGCGTCCGGCTGCAGCTGCGCTATGACGCGCCC
GGAGGGGCAGTAGTGCTACCACTGGTACTGGAGGTGGAGGTGGTCTTCACCCAGCTGGAG
GTTGTGACTCGGAACTTGCCTCTGGTCGTGGAAGAGCTGCTGGGGACCAGCAATGCCCTG
GACGCGCGGAGCCTGGAGTTCGCCTTCCAGCCCGAGACAGAGGAGTGCCGCGTGGGCATC
CTGTCCGGCTTGGGCGCGCTGCCTCGCTATGGAGAACTCCTCCACTACCCGCAGGTCCCT
GGAGGAGCCAGAGAGGGAGGCGCCCCGGAGACTCTCCTGATGGACTGCAAAGCTTTCCAG
GAACTAGGCGTGCGCTATCGCCACACAGCCGCCAGTCGCTCACCAAACAGGGACTGGATA
CCCATGGTGGTGGAGCTGCGTTCACGAGGGGCTCCTGTGGGCAGCCCTGCTTTGAAACGC
GAGCACTTCCAGGTTCTGGTGAGGATCCGAGGAGGGGCCGAGAACACTGCACCCAAGCCC
AGTTTCGTGGCCATGATGATGATGGAGGTGGACCAGTTTGTACTGACGGCCCTGACCCCA
GACATGCTGGCAGCCGAGGATGCTGAGTCTCCCTCTGACCTGTTGATCTTCAACCTTACT
TCTCCATTCCAGCCTGGCCAGGGCTACTTGGTGAGCACCGATGATCGCAGCCTGCCCCTT
TCCTCCTTCACTCAGAGGGATCTGCGGCTCCTGAAGATTGCCTACCAGCCCCCTTCTGAA
GACTCTGACCAGGAGCGCCTCTTTGAACTGGAATTGGAGGTAGTGGATCTAGAAGGAGCA
GCTTCAGACCCTTTTGCCTTCATGGTAGTGGTGAAGCCCATGAACACAATGGCTCCGGTG
GTCACCCGGAATACCGGTCTTATTCTCTATGAGGGTCAGTCTCGGCCCCTCACAGGCCCT
GCAGGCAGTGGTCCGCAAAACTTGGTCATCAGCGATGAGGATGACCTAGAAGCAGTGCGG
CTAGAGGTGGTGGCTGGGCTCCGGCATGGTCACCTTGTCATTCTGGGTGCTTCCAGTGGC
AGCTCTGCTCCCAAGAGCTTTACAGTGGCTGAGCTGGCAGCCGGCCAGGTGGTCTACCAG
CATGATGACAGAGACGGCTCGCTGAGCGACAACCTGGTGCTTCGCATGGTGGATGGAGGA
GGCAGGCACCAGGTACAGTTTCTGTTCCCCATCACCTTAGTGCCTGTGGATGACCAGCCA
CCTGTTCTCAATGCCAACACGGGGCTGACACTGGCAGAGGGTGAAACAGTGCCCATCCTG
CCCCTTTCCCTGAGTGCAACTGACATGGATTCAGATGATTCTCTGCTGCTTTTTGTGCTG
GAGTCACCCTTCTTAACTACGGGGCATCTGCTTCTCCGCCAAACTCACCCTCCCCATGAG
AAGCAGGAACTTCTCAGAGGCCTTTGGAGGAAGGAGGGGGCATTTTATGAGCGAACAGTG
ACAGAGTGGCAGCAGCAGGACATAACAGAGGGCAGGCTGTTCTATAGACACTCTGGGCCC
CATAGTCCTGGGCCAGTCACAGACCAGTTCACATTTAGAGTCCAGGATAACCATGACCCT
CCTAATCAGTCCGGGCTACAGCGGTTTGTGATTCGTATCCATCCTGTGGATCGCCTCCCT
CCGGAGCTGGGCAGTGGCTGTCCCCTTCGTATGGTGGTACAGGAATCCCAGCTCACACCA
CTGAGGAAGAAGTGGCTGCGCTACACTGACCTGGACACAGATGACCGAGAACTACGTTAC
ACAGTGACTCAGTCCCCCACAGACACAGACGAAAATCACCTGCCAGCCCCACTGGGTACC
TTGGTCTTGACTGACAACCCCTCAGTCGTGGTGACCCATTTTACCCAAGCCCAGATCAAC
CATCATAAAATTGCTTACAGACCCCCGGGTCAAGAACTGGGCGTGGCTACTCGAGTGGCC
CAGTTCCAGTTCCAGGTGGAAGACCGAGCTGGGAATGTGGCTCCAGGTACCTTTACCCTT
TACTTGCATCCCGTGGACAACCAGCCACCTGAGATCCTCAACACCGGCTTCACTATTCAG
GAGAAGGGTCACCACATCCTGAGTGAGACAGAGTTGCACGTGAATGATGTAGACACTGAT
GTTGCCCATATCTCTTTCACTCTCACTCAGGCACCCAAACATGGCCACATGAGAGTGTCT
GGACAGATCCTGCATGTAGGGGGTCTCTTCCACTTGGAGGACATAAAACAGGGCCGAGTT
TCCTATGCCCATAATGGGGACAAGTCCCTGACTGATAGCTGCTCCTTGGAAGTCAGTGAC
AGACATCATGTGGTGCCCATCACTCTCAGAGTAAATGTCCGGCCAGTGGATGATGAAGTG
CCCATACTGAGCCATCCTACTGGCACTCTGGAGTCCTATCTAGATGTCTTAGAAAATGGG
GCTACTGAAATCACTGCCAATGTTATTAAGGGGACCAATGAGGAAACTGATGACTTGATG
TTGACTTTCCTCTTGGAAGATCCACCTTTGTATGGGGAAATCTTGGTCAATGGCATTCCA
GCAGAGCAGTTTACTCAAAGGGACATCTTGGAGGGCTCTGTTGTATATACCCACACCAGT
GGTGAGATAGGCCTATTGCCTAAAGCGGATTCTTTTAACCTGAGTCTGTCAGATATGTCT
CAAGAATGGAGAATTGGTGGCAATACTATCCAAGGAGTTACTATATGGGTGACCATCCTG
CCTGTTGATAGCCAGGCCCCAGAAATCTTTGTAGGTGAACAGTTGATAGTAATGGAAGGT
GATAAAAGTGTTATAACATCAGTGCATATAAGTGCTGAAGATGTCGACTCCCTGAATGAT
GACATCTTGTGCACTATAGTTATTCAGCCTACTTCAGGTTATGTTGAAAACATTTCTCCA
GCACCAGGCTCTGAGAAATCAAGAGCAGGGATTGCCATAAGTGCTTTCAACTTGAAAGAT
CTCAGGCAGGGCCACATAAACTATGTCCAGAGTGTCCATAAAGGGGTGGAACCTGTGGAG
GACCGATTTGTATTTCGTTGTTCTGATGGCATTAACTTTTCAGAGAGACAGTTCTTCCCC
ATTGTAATCATTCCCACCAATGATGAACAGCCAGAGATGTTTATGAGAGAATTTATGGTG
ATGGAAGGCATGAGTCTGGTAATTGATACACCCATTCTCAATGCTGCTGATGCTGATGTT
CCCCTGGATGATTTAACTTTCACTATTACCCAATTCCCCACTCATGGTCACATCATGAAT
CAGCTGATAAATGGCACGGTTTTGGTCGAAAGCTTCACCTTGGATCAGATCATAGAGAGT
TCCAGCATTATTTATGAGCATGATGACTCCGAGACCCAGGAAGACAGTTTTGTGATTAAA
CTAACAGATGGGAAGCACTCTGTGGAAAAGACGGTCCTCATTATAGTTATCCCTGTTGAT
GATGAGACGCCCAGAATGACTATCAATAATGGACTAGAAATAGAAATTGGGGATACCAAG
ATTATCAACAACAAAATATTAATGGCAACAGATTTAGATTCAGAAGACAAATCTTTGGTT
TATATTATTCGTTATGGGCCAGGACATGGCTTATTACAGAGACGAAAACCTACTGGTGCC
TTTGAAAATATCACACTGGGCATGAATTTTACCCAGGATGAAGTAGACAGAAACTTAATT
CAGTATGTCCATTTGGGGCAAGAGGGCATTCGGGACCTAATTAAATTTGATGTGACTGAT
GGAATAAATCCCCTCATAGATCGTTACTTTTATGTGTCCATCGGGAGCATTGACATTGTC
TTCCCTGATGTGATAAGTAAGGGAGTGTCCTTGAAAGAAGGTGGCAAAGTCACTCTTACA
ACAGACCTACTAAGCACTAGTGACTTGAACAGTCCTGATGAAAACTTGGTTTTTACCATC
ACCAGGGCTCCCATGCGAGGTCACCTGGAATGCACGGATCAGCCTGGTGTGTCCATCACG
TCTTTCACTCAGCTGCAACTGGCTGGAAACAAAATCTACTACATCCACACAGCTGATGAT
GAAGTGAAAATGGACAGTTTTGAGTTTCAAGTCACCGATGGACGTAACCCTGTCTTTCGG
ACATTCCGTATCTCCATTAGCGATGTGGACAATAAAAAGCCAGTGGTCACCATCCACAAG
CTGGTTGTCAGTGAAAGTGAAAACAAGCTGATTACTCCTTTTGAGCTCACTGTCGAAGAC
AGAGATACTCCTGACAAGCTCCTGAAATTCACTATCACCCAGGTGCCTATTCATGGCCAT
CTCCTATTCAACAATACCAGACCTGTCATGGTTTTTACCAAGCAAGACTTGAATGAAAAC
TTAATCAGCTACAAACATGATGGCACTGAGTCAAGTGAAGATAGCTTCTCCTTCACAGTG
ACTGATGGCACCCATACAGACTTCTATGTTTTTCCTGATACGGTGTTTGAAACAAGGAGA
CCCCAAGTGATGAAGATCCAGGTCTTGGCTGTTGACAACAGTGTCCCCCAAATCGCAGTG
AATAAGGGGGCCTCTACACTTCGCACTCTAGCCACTGGCCACTTGGGGTTCATGATCACA
AGCAAAATATTGAAAGTGGAGGACAGAGACAGCTTACACATTTCTCTTAGATTTATCGTG
ACAGAGGCCCCTCAACATGGATATCTTCTCAACCTGGACAAAGGCAACCACAGCATCACT
CAGTTCACACAAGCTGACATTGATGACATGAAAATATGCTATGTCTTAAGAGAAGGGGCT
AATGCCACAAGTGATATGTTCTATTTTGCAGTTGAAGATGGTGGTGGAAACAAGTTAACG
TACCAGAATTTTCGTCTGAATTGGGCATGGATCTCCTTTGAAAAGGAATATTACCTGGTC
AATGAGGACTCCAAATTTCTAGATGTTGTTCTTAAACGTAGAGGTTACTTGGGAGAAACT
TCTTTTATAAGTATTGGCACAAGAGACAGAACTGCAGAAAAAGACAAAGACTTCAAGGGC
AAAGCACAGAAACAAGTGCAGTTCAACCCAGGCCAGACCAGGGCCACATGGCGAGTGCGG
ATCCTGAGTGATGGGGAGCATGAGCAGTCTGAAACCTTTCAGGTGGTACTCTCAGAGCCC
GTGCTGGCTGCCTTGGAATTCCCCACAGTCGCCACTGTTGAGATCGTTGATCCAGGAGAT
GAGCCAACTGTGTTTATTCCCCAGTCCAAATACTCCGTTGAAGAAGATGTTGGTGAGCTG
TTCATTCCCATCAGGAGGAGCGGAGATGTGAGCCAGGAGTTGATGGTGGTCTGTTATACC
CAACAAGGAACAGCAACTGGAACTGTGCCGACTTCCGTGTTGTCTTACTCTGATTACATA
TCCAGGCCTGAGGACCACACCAGTGTTGTCCGCTTTGACAAAGATGAACGGGAGAAACTG
TGTCGGATAGTCATAATTGATGACTCTTTGTACGAGGAGGAGGAAACCTTCCATGTCCTT
CTGAGCATGCCCATGGGGGGAAGAATCGGATCAGAGTTCCCAGGGGCTCAAGTTACAATC
GTTCCTGACAAAGATGATGAACCCATCTTTTACTTCGGTGATGTGGAATACTCTGTGGAT
GAGAGTGCTGGCTATGTGGAAGTGCAGGTGTGGAGAACGGGCACTGACCTGTCCAAGTCT
TCTAGTGTCACAGTGAGGTCTCGGAAAACAGATCCTCCCTCTGCAGATGCTGGAACAGAC
TATGTGGGCATCAGCCGTAATTTAGATTTTGCACCTGGAGTCAACATGCAGCCTGTTCGT
GTTGTCATTCTGGATGACCTTGGACAACCAGCGCTGGAGGGAATTGAGAAATTTGAACTG
GTGCTTCGCATGCCTATGAACGCAGCCCTTGGCGAGCCCAGCAAAGCCACAGTGTCCATA
AATGACTCTGTCTCCGATTTGCCTAAGATGCAATTCAAAGAACGAATATATACTGGCAGC
GAAAGTGATGGGCAGATAGTTACAATGATCCATAGGACTGGGGATGTCCAGTACAGATCT
TCAGTGAGATGCTACACCCGGCAGGGGTCTGCACAGGTGATGATGGACTTTGAAGAACGC
CCAAACACTGATACCTCCATCATCACATTCCTCCCTGGTGAGACAGAAAAGCCCTGCATT
CTTGAGCTGATGGACGATGTGCTCTATGAGGAGGTAGAGGAGCTCCGCCTGGTACTCGGC
ACTCCACAAAGCAACTCTCCCTTTGGGGCTGCAGTTGGTGAACAAAATGAAACTCTCATA
AGGATCCGAGATGATGCTGATAAGACTGTTATTAAATTTGGAGAAACCAAATTTAGTGTC
ACTGAACCCAAAGAACCTGGAGAGTCGGTGGTTATAAGAATTCCAGTGATTCGCCAAGGA
GACACTTCAAAGGTTTCCATTGTGAGAGTCCACACCAAGGATGGCTCGGCCACCTCTGGA
GAAGACTACCACCCTGTGTCAGAAGAAATTGAGTTTAAGGAAGGGGAAACCCAGCACGTG
GTTGAAATCGAAGTTACCTTTGACGGGGTGAGAGAGATGAGAGAGGCCTTCACTGTTCAC
CTAAAACCTGATGAAAATATGATAGCAGAGATGCAGTTGACGAAAGCCATTGTGTACATA
GAAGAAATGAGCAGCATGGCAGATGTCACTTTTCCTTCTGTCCCTCAAATTGTATCCCTG
TTGATGTATGACGACACTTCCAAAGCTAAGGAGAGTGCTGAACCCATGTCTGGCTATCCT
GTCATCTGTATCACAGCTTGCAACCCCAAATATTCAGACTACGATAAAACAGGCTCTATC
TGTGCAAGTGAGAACATCAATGACACTTTGACGCGGTACCGGTGGCTGATTAGTGCACCT
GCGGGCCCTGACGGTGTGACCAGCCCTATGAGAGAAGTGGACTTCGACACCTTTTTTACG
TCATCCAAGATGGTCACACTGGACTCCATATACTTTCAGCCTGGCTCCCGGGTACAGTGC
GCAGCTCGTGCTGTGAACACCAATGGGGATGAAGGCCTGGAGCTCATGAGCCCTATTGTA
ACCATCAGCAGAGAAGAAGGTCTTTGTCAGCCCCGTGTACCTGGGGTTGTTGGAGCAGAG
CCGTTCTCAGCTAAATTGCGCTACACAGGCCCTGAGGATGCAGACTACACAAACCTTATC
AAGCTCACTGTCACAATGCCACACATAGATGGCATGCTCCCCGTGATCTCCACTAGAGAG
CTTTCCAACTTTGAGCTCACCCTCAGCCCTGATGGCACAAGAGTTGGAAACCACAAGTGC
TCCAACCTCCTGGATTATACTGAAGTGAAGACTCATTATGGTTTCTTGACTGATGCTACC
AAAAATCCAGAAATAATTGGAGAGACATATCCTTACCAGTACAGCTTGTCCATCAGAGGT
TCCACTACCTTGCGCTTCTACCGGAACCTGAACCTAGAGGCCTGTTTATGGGAGTTCGTT
AGCTACTATGACATGTCAGAACTCCTTGCTGACTGTGGTGGCACCATTGGAACAGATGGA
CAGGTCCTAAACCTAGTGCAGTCCTATGTGACCCTTCGAGTCCCTCTGTATGTTTCCTAC
GTGTTCCATTCCCCCGTGGGGGTAGGAGGCTGGCAGCATTTTGACTTGAAGTCAGAGCTT
CGTCTAACTTTTGTGTACGACACCGCCATCTTGTGGAATGATGGAATTGGCAGCCCCCCA
GAGGCTGAACTTCAAGGTTCTCTCTATCCAACCAGCATGCGCATCGGTGATGAGGGGCGC
TTGGCCGTGCACTTCAAGACAGAGGCTCAGTTCCATGGCTTATTTGTGCTGTCACATCCC
GCATCCTTTACAAGCTCAGTGATCATGTCAGCTGATCATCCAGGCCTGACATTTTCCCTC
CGCCTCATAAGGAGTGAACCAACCTATAACCAGCCAGTACAGCAGTGGAGCTTTGTCTCT
GACTTTGCCGTACGTGACTACTCAGGGACCTATACTGTGAAGCTGGTGCCATGCACTGCC
CCATCACATCAGGAATACCGCCTGCCAGTCACCTGCAACCCCAGAGAACCTGTCACCTTT
GACCTTGACATCCGATTCCAACAGGTCAGTGATCCAGTGGCTGCTGAGTTTAGCTTGAAC
ACCCAAATGTACCTGCTCTCTAAGAAGAGTCTCTGGTTGTCTGATGGATCCATGGGATTC
GGGCAAGAGAGTGATGTTGCTTTTGCAGAAGGTGATATAATTTATGGTCGTGTCATGGTG
GATCCTGTCCAGAATCTGGGTGACTCCTTTTACTGCAGCATTGAGAAGGTGTTTCTATGC
ACTGGAGCTGATGGCTATGTTCCCAAGTATAGTCCAATGAATGCAGAATATGGCTGCTTA
GCCGACTCTCCTTCACTCTTATATAGATTTAAAATTGTGGACAAAGCTCAGCCAGAGACA
CAAGCGACCAGTTTTGGAAATGTCCTATTTAATGCCAAACTAGCAGTGGATGACCCTGAA
GCCATTCTCTTAGTGAATCAGCCTGGATCTGATGGATTTAAAGTCGACTCAACACCACTC
TTTCAGGTCGCTCTAGGCCGAGAATGGTATATACATACGATCTATACAGTGAGATCGAAA
GACAATGCCAATCGAGGTATTGGCAAAAGAAGTGTGGAGTACCATTCTCTGGTGAGTCAA
GGAAAGCCCCAATCCACCACCAAGAGCCGGAAGAAGAGAGAGATCAGGAGCACACCCTCA
CTGGCATGGGAGATTGGTGCTGAAAACAGTCGAGGAACAAACATCCAGCACATTGCCCTG
GACCGCACCAAGAGGCAGATCCCCCATGGGAGAGCACCTCCAGATGGCATCCTCCCCTGG
GAGCTCAACAGCCCCAGCTCTGCAGTCAGCCTGGTCACTGTGGTGGGAGGCACCACGGTA
GGGTTACTCACCATCTGCCTCACTGTCATTGCAGTGCTGATGTGCAGGGGCAAGGAAAGT
TTCAGGGGGAAGGATGCCCCGAAAGGCTCCAGCAGCAGTGAGCCCATGGTGCCCCCACAG
AGCCATCACAATGACAGCTCAGAAGTTTGA
Protein Properties
Number of Residues 3169
Molecular Weight 351154.0
Theoretical pI 4.65
Pfam Domain Function
Signals
  • 1-46
Transmembrane Regions
  • 3114-3134
Protein Sequence
>FRAS1-related extracellular matrix protein 2
MHSAGTPGLSSRRTGNSTSFQPGPPPPPRLLLLLLLLLSLVSRVPAQPAAFGRALLSPGL
AGAAGVPAEEAIVLANRGLRVPFGREVWLDPLHDLVLQVQPGDRCAVSVLDNDALAQRPG
RLSPKRFPCDFGPGEVRYSHLGARSPSRDRVRLQLRYDAPGGAVVLPLVLEVEVVFTQLE
VVTRNLPLVVEELLGTSNALDARSLEFAFQPETEECRVGILSGLGALPRYGELLHYPQVP
GGAREGGAPETLLMDCKAFQELGVRYRHTAASRSPNRDWIPMVVELRSRGAPVGSPALKR
EHFQVLVRIRGGAENTAPKPSFVAMMMMEVDQFVLTALTPDMLAAEDAESPSDLLIFNLT
SPFQPGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQPPSEDSDQERLFELELEVVDLEGA
ASDPFAFMVVVKPMNTMAPVVTRNTGLILYEGQSRPLTGPAGSGPQNLVISDEDDLEAVR
LEVVAGLRHGHLVILGASSGSSAPKSFTVAELAAGQVVYQHDDRDGSLSDNLVLRMVDGG
GRHQVQFLFPITLVPVDDQPPVLNANTGLTLAEGETVPILPLSLSATDMDSDDSLLLFVL
ESPFLTTGHLLLRQTHPPHEKQELLRGLWRKEGAFYERTVTEWQQQDITEGRLFYRHSGP
HSPGPVTDQFTFRVQDNHDPPNQSGLQRFVIRIHPVDRLPPELGSGCPLRMVVQESQLTP
LRKKWLRYTDLDTDDRELRYTVTQSPTDTDENHLPAPLGTLVLTDNPSVVVTHFTQAQIN
HHKIAYRPPGQELGVATRVAQFQFQVEDRAGNVAPGTFTLYLHPVDNQPPEILNTGFTIQ
EKGHHILSETELHVNDVDTDVAHISFTLTQAPKHGHMRVSGQILHVGGLFHLEDIKQGRV
SYAHNGDKSLTDSCSLEVSDRHHVVPITLRVNVRPVDDEVPILSHPTGTLESYLDVLENG
ATEITANVIKGTNEETDDLMLTFLLEDPPLYGEILVNGIPAEQFTQRDILEGSVVYTHTS
GEIGLLPKADSFNLSLSDMSQEWRIGGNTIQGVTIWVTILPVDSQAPEIFVGEQLIVMEG
DKSVITSVHISAEDVDSLNDDILCTIVIQPTSGYVENISPAPGSEKSRAGIAISAFNLKD
LRQGHINYVQSVHKGVEPVEDRFVFRCSDGINFSERQFFPIVIIPTNDEQPEMFMREFMV
MEGMSLVIDTPILNAADADVPLDDLTFTITQFPTHGHIMNQLINGTVLVESFTLDQIIES
SSIIYEHDDSETQEDSFVIKLTDGKHSVEKTVLIIVIPVDDETPRMTINNGLEIEIGDTK
IINNKILMATDLDSEDKSLVYIIRYGPGHGLLQRRKPTGAFENITLGMNFTQDEVDRNLI
QYVHLGQEGIRDLIKFDVTDGINPLIDRYFYVSIGSIDIVFPDVISKGVSLKEGGKVTLT
TDLLSTSDLNSPDENLVFTITRAPMRGHLECTDQPGVSITSFTQLQLAGNKIYYIHTADD
EVKMDSFEFQVTDGRNPVFRTFRISISDVDNKKPVVTIHKLVVSESENKLITPFELTVED
RDTPDKLLKFTITQVPIHGHLLFNNTRPVMVFTKQDLNENLISYKHDGTESSEDSFSFTV
TDGTHTDFYVFPDTVFETRRPQVMKIQVLAVDNSVPQIAVNKGASTLRTLATGHLGFMIT
SKILKVEDRDSLHISLRFIVTEAPQHGYLLNLDKGNHSITQFTQADIDDMKICYVLREGA
NATSDMFYFAVEDGGGNKLTYQNFRLNWAWISFEKEYYLVNEDSKFLDVVLKRRGYLGET
SFISIGTRDRTAEKDKDFKGKAQKQVQFNPGQTRATWRVRILSDGEHEQSETFQVVLSEP
VLAALEFPTVATVEIVDPGDEPTVFIPQSKYSVEEDVGELFIPIRRSGDVSQELMVVCYT
QQGTATGTVPTSVLSYSDYISRPEDHTSVVRFDKDEREKLCRIVIIDDSLYEEEETFHVL
LSMPMGGRIGSEFPGAQVTIVPDKDDEPIFYFGDVEYSVDESAGYVEVQVWRTGTDLSKS
SSVTVRSRKTDPPSADAGTDYVGISRNLDFAPGVNMQPVRVVILDDLGQPALEGIEKFEL
VLRMPMNAALGEPSKATVSINDSVSDLPKMQFKERIYTGSESDGQIVTMIHRTGDVQYRS
SVRCYTRQGSAQVMMDFEERPNTDTSIITFLPGETEKPCILELMDDVLYEEVEELRLVLG
TPQSNSPFGAAVGEQNETLIRIRDDADKTVIKFGETKFSVTEPKEPGESVVIRIPVIRQG
DTSKVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHVVEIEVTFDGVREMREAFTVH
LKPDENMIAEMQLTKAIVYIEEMSSMADVTFPSVPQIVSLLMYDDTSKAKESAEPMSGYP
VICITACNPKYSDYDKTGSICASENINDTLTRYRWLISAPAGPDGVTSPMREVDFDTFFT
SSKMVTLDSIYFQPGSRVQCAARAVNTNGDEGLELMSPIVTISREEGLCQPRVPGVVGAE
PFSAKLRYTGPEDADYTNLIKLTVTMPHIDGMLPVISTRELSNFELTLSPDGTRVGNHKC
SNLLDYTEVKTHYGFLTDATKNPEIIGETYPYQYSLSIRGSTTLRFYRNLNLEACLWEFV
SYYDMSELLADCGGTIGTDGQVLNLVQSYVTLRVPLYVSYVFHSPVGVGGWQHFDLKSEL
RLTFVYDTAILWNDGIGSPPEAELQGSLYPTSMRIGDEGRLAVHFKTEAQFHGLFVLSHP
ASFTSSVIMSADHPGLTFSLRLIRSEPTYNQPVQQWSFVSDFAVRDYSGTYTVKLVPCTA
PSHQEYRLPVTCNPREPVTFDLDIRFQQVSDPVAAEFSLNTQMYLLSKKSLWLSDGSMGF
GQESDVAFAEGDIIYGRVMVDPVQNLGDSFYCSIEKVFLCTGADGYVPKYSPMNAEYGCL
ADSPSLLYRFKIVDKAQPETQATSFGNVLFNAKLAVDDPEAILLVNQPGSDGFKVDSTPL
FQVALGREWYIHTIYTVRSKDNANRGIGKRSVEYHSLVSQGKPQSTTKSRKKREIRSTPS
LAWEIGAENSRGTNIQHIALDRTKRQIPHGRAPPDGILPWELNSPSSAVSLVTVVGGTTV
GLLTICLTVIAVLMCRGKESFRGKDAPKGSSSSEPMVPPQSHHNDSSEV
GenBank ID Protein 79749430
UniProtKB/Swiss-Prot ID Q5SZK8
UniProtKB/Swiss-Prot Entry Name FREM2_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_207361.4
GeneCard ID FREM2
GenAtlas ID FREM2
HGNC ID HGNC:25396
References
General References
  1. Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S: Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 2004 Jan;36(1):40-5. Epub 2003 Dec 21. [PubMed:14702039 ]
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