Hmdb loader
Identification
HMDB Protein ID HMDBP07918
Secondary Accession Numbers
  • 13629
Name Protocadherin gamma-A9
Synonyms
  1. PCDH-gamma-A9
Gene Name PCDHGA9
Protein Type Unknown
Biological Properties
General Function Involved in calcium ion binding
Specific Function Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain
Pathways Not Available
Reactions Not Available
GO Classification
Component
membrane
cell part
plasma membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
cell adhesion
cellular process
cell-cell adhesion
homophilic cell adhesion
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
Gene Properties
Chromosome Location Chromosome:5
Locus 5q31
SNPs PCDHGA9
Gene Sequence
>2799 bp
ATGGCAGCTCCAACCAAATGCCAGCTCCGCGGAAGATTAGTCCTGCTATGCTCGCTCCTG
GGGATGCTATGGGAGGCCAGGGCCAGTCAGATTCGCTACTCAGTGCCTGAAGAGACAGAA
AAGGGCTATATTGTGGGCAACATCTCCAAGGACCTGGCTCTGGAGCCCCGGGAGCTGGCG
GAGCGCCGAGTCCGCATCGTCTCTAGAGGTAGGACGCAGCTTTTCTCTCTGAACCCGCGC
AGCGGCACCTTGGTCACCGCGGGTAGGATAGACCGGGAGGAGCTCTGTGCTCAGAGCCCG
CGGTGTCTGGTGAACTTTAAAGTCCTGGTTGAAGACAGAGTGAAACTGTACGGAATAGAA
ATAGAAGTAACTGATATTAACGACAGCGCCCCAAAGTTCCAGGCCGAAAGTCTGGAAGTA
AAAATTAACGAAATCGCGGTTCCTGGAGCACGTTATCCACTTCCAGAAGCTATTGATCCG
GATGTTGGCGTGAACTCCCTCCAGAGCTACCAGCTCAGCCCCAATCACCACTTCTCCCTG
AACGTGCAGACTGGAGACAATGGAGCCATAAACCCAGAGCTGGTGCTGGAGCGCGCCCTG
GACAGGGAGGAGGCAACTGCCCACCACCTGGTCCTCACGGCCTCGGATGGCGGCGAGCCG
CGTCGCTCCAGCACAGTGCGCATCCATGTGACAGTGTTGGATACAAATGATAATGCCCCG
GTTTTTGCTCAACGGATTTACCGAGTTAAAGTCCTTGAGAACGTGCCCCCAGGCACCTGG
CTGCTTACTGCAACAGCCAGCGACCTGGATGAGGGAATCAACGGAAAAGTGGCATACAAA
TTCTGGAAAATTAATGAAAAACAATCTCTGCTATTCCAGCTTAATGAAAATACTGGGGAA
ATATCAACAGCAAAAAGTCTAGATTATGAAGAATGTTCATTTTATGAAATGGAAATACAA
GCTGAAGATGGTGGGGGATTGAAAGGGTGGACAAAAGTGCTCATTTCGGTGGAAGATGTA
AATGACAATAGACCTGAAGTGACCATTACATCTCTGTTTAGCCCAGTGAGAGAAGACGCA
CCTCAGGGAACAGTAATTCTTCTTTTCAATGCTCATGACCGAGACTCCGGGAAGAATGGT
CAAGTTGTCTGTTCTATCCAGGAGAATCTATCTTTTACATTAGAAAATTCAGAAGAAGAT
TATTACAGATTGTTGACGGCCCAAATTCTTGACCGAGAAAAAGCCTCAGAATATAATATC
ACGGTGACTGCAACAGACAGAGGAACTCCGCCCCTGTCCACAGAAATTCACATCACCCTG
CAAGTGACTGACATCAATGATAATCCACCTGCTTTCTCTCAAGCCTCCTACTCAGTCTAC
CTCCCGGAAAACAACGCCAGAGGTACTTCCATCTTCTCCGTGATTGCCTATGACCCTGAT
AGCAATGAGAATTCTAGAGTTATTTACTCCTTGGCAGAGGATACCATCCAAGGGTCTCCT
CTCTCCACCTATGTCTCTATTAACTCAGACACTGGTGTGCTGTATGCTCTGTGCTCCTTT
GACTATGAGCAGTTTAGAGATTTGCAAATGCAGGTGACGGCAAGTGACAGTGGAAGCCCA
CCACTTAGCAGCAATGTGTCATTGAGACTGTTTGTTTTGGACCAGAATGACAATGCCCCA
GAAATCCTGTACCCTGCCCTCCCCACTGATGGTTCTACTGGTGTGGAGCTGGCACCCCGC
TCTGCAGAGCCTGGCTACCTGGTGACCAAGGTGGTGGCAGTGGACAGAGACTCAGGCCAG
AATGCTTGGCTCTCCTACCGCCTATTCAAGGCCAGTGAGCCAGGGCTCTTCTCGGTGGGG
CTGCACACAGGTGAAGTGCGCACAGCTCGGGCCCTGCTAGATAGAGATGCGCTCAAACAG
AGCCTTGTGGTGGCTGTACAGGACCATGGCCAGCCCCCTCTCTCGGCCACTGTCACGCTC
ACAGTAGCCATAGCTGACAGCATCCCAGACATCCTGGCTGACCTGGGCAGTCTTCAGATC
CCTGCAGACCTGGAGGCCTCAGACCTTACCCTCTACCTCGTTGTGGCTGTGGCAGTCGTC
TCCTGTGTCTTCCTCACCTTCGTTATCACGCTGCTGGCCCTCAGGCTGAGGCACTGGCAC
TCCTCGCATCTGCTGCGGGCTACCAGTGATGGGTTGGCTGGTGTGCCCACCTCACACTTT
GTGGGTGTAGATGGGGTTCGAGCTTTCCTACAGACCTATTCTCAGGAGTTCTCCCTCACC
GCTGACTCAAGGAAGAGTCACCTGATCTTCCCCCAGCCCAACTATGCAGACACACTCATC
AGCCAGCAGAGCTGTGAGAAAAATGAGCCTTTGTGCGTCTCTGTTGATTCCAAGTTTCCT
ATAGAAGACACCCCTTTGGTTCCGCAAGCCCCGCCCAACACGGACTGGCGTTTCTCTCAG
GCCCAGAGACCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGCACCTGGCCCAAC
AACCAGTTTGACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGTGAAGCTGCT
GATGGGAGCTCCACCCTGGGAGGGGGTGCCGGCACCATGGGATTGAGCGCCCGCTACGGA
CCCCAGTTCACCCTGCAGCACGTGCCCGACTACCGCCAGAATGTCTACATCCCAGGCAGC
AATGCCACACTGACCAACGCAGCTGGCAAGCGGGATGGCAAGGCCCCAGCAGGTGGCAAT
GGCAACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAA
Protein Properties
Number of Residues 932
Molecular Weight 101686.0
Theoretical pI 4.66
Pfam Domain Function
Signals
  • 1-28
Transmembrane Regions
  • 693-713
Protein Sequence
>Protocadherin gamma-A9
MAAPTKCQLRGRLVLLCSLLGMLWEARASQIRYSVPEETEKGYIVGNISKDLALEPRELA
ERRVRIVSRGRTQLFSLNPRSGTLVTAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIE
IEVTDINDSAPKFQAESLEVKINEIAVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSL
NVQTGDNGAINPELVLERALDREEATAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAP
VFAQRIYRVKVLENVPPGTWLLTATASDLDEGINGKVAYKFWKINEKQSLLFQLNENTGE
ISTAKSLDYEECSFYEMEIQAEDGGGLKGWTKVLISVEDVNDNRPEVTITSLFSPVREDA
PQGTVILLFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNI
TVTATDRGTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAYDPD
SNENSRVIYSLAEDTIQGSPLSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDSGSP
PLSSNVSLRLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQ
NAWLSYRLFKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTL
TVAIADSIPDILADLGSLQIPADLEASDLTLYLVVAVAVVSCVFLTFVITLLALRLRHWH
SSHLLRATSDGLAGVPTSHFVGVDGVRAFLQTYSQEFSLTADSRKSHLIFPQPNYADTLI
SQQSCEKNEPLCVSVDSKFPIEDTPLVPQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN
NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS
NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
GenBank ID Protein 5456952
UniProtKB/Swiss-Prot ID Q9Y5G4
UniProtKB/Swiss-Prot Entry Name PCDG9_HUMAN
PDB IDs Not Available
GenBank Gene ID AF152329
GeneCard ID PCDHGA9
GenAtlas ID PCDHGA9
HGNC ID HGNC:8707
References
General References
  1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]
  2. Wu Q, Maniatis T: A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell. 1999 Jun 11;97(6):779-90. [PubMed:10380929 ]