| Identification |
|---|
| HMDB Protein ID
| HMDBP07919 |
| Secondary Accession Numbers
| |
| Name
| Protocadherin gamma-A10 |
| Synonyms
|
- PCDH-gamma-A10
|
| Gene Name
| PCDHGA10 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHGA10 |
| Gene Sequence
|
>2811 bp
ATGGCCGCTCAAAGGAATCGCTCAAAGGAATCAAAGGATTGCAGCGGGCTGGTCCTGCTC
TGCCTTTTCTTCGGGATTCCATGGGAGGCTGGAGCCCGGCAGATCTCCTACTCAATTCCT
GAGGAATTAGAGAAAGGCTCTTTCGTGGGCAACATCTCCAAGGACTTGGGTCTGGCGCCC
CGGGAGCTGGCGGAGCGCGGAGTCCGCATAGTCTCCAGAGGTAGGACGCAGCTTTTCTCT
CTGAACCCGCGCAGCGGCAGCTTGATCACCGCGGGCAGGATAGACCGGGAGGAGCTCTGC
GCTCAGAGCGCGCGGTGCGTGGTGAGTTTTAATATCCTTGTGGAAGACAGGGTGAAACTT
TTTGGGATAGAAATAGAAGTAACTGATATCAATGACAATGCTCCAAAATTCCAAGCAGAA
AATCTAGACGTAAAAATTAATGAAAATGTCGCTGCGGGAATGCGTTTTCCTCTCCCGGAA
GCTATTGATCCGGATGTGGGCGTGAACTCCCTGCAGAGCTATCAGCTCAGCCCCAATAAG
CACTTCTCCCTAAGAGTTCAGAGCCGTGCCAATGGCGTCAAGTACCCGGAGCTGGTACTG
GAGCACTCCCTAGATCGCGAGGAAGAGGCCATTCACCACCTGGTCCTCACCGCCTCCGAC
GGGGGTGACCCTCTCCGATCTGGCACTGTCCTTGTCAGTGTGACTGTCTTCGATGCAAAT
GACAACGCGCCGGTCTTCACCTTGCCAGAATACCGAGTGAGTGTTCCTGAGAATTTGCCT
GTGGGCACTCAGCTGCTGACAGTCACAGCCACCGACAGGGACGAAGGTGCCAATGGAGAA
GTGACATATTCATTCCGAAAATTACCTGACACGCAATTGTTGAAGTTCCAACTAAACAAA
TATACTGGAGAAATAAAAATATCAGAAAATCTAGATTATGAAGAAACCGGTTTCTATGAA
ATAGAAATACAAGCAGAAGATGGAGGAGCATATCTTGCAACTGCAAAAGTGTTGATTACA
GTAGAAGATGTAAATGACAACAGTCCAGAGCTGACCATCACGTCTCTATTTAGTCCAGTG
ACTGAAGATTCACCTCTGGGAACAGTCGTAGCCCTTTTAAATGTGCATGATTTAGACTCT
GAGCAGAATGGACAGGTAACCTGTTCCATTTTGGCGTATCTACCATTTAAATTAGAAAAG
TCCATTGACAGTTATTACAGATTGGTGATACACAGAGCCCTTGACAGGGAACAGGTATCC
TCTTACAATATCACAGTGACAGCCACAGATGGGGGAAGTCCTCCTCTATCAACGGAAGCT
CACTTTATGCTACAAGTGGCAGATATCAATGACAACCCACCTACCTTCTCTCAAGTCTCC
TACTTTACCTATATCCCAGAGAACAACGCCAGGGGTGCCTCCATCTTCTCAGTGACAGCG
CTGGACCCGGACAGCAAAGAGAATGCCCAGATTATTTACTCCCTGGCTGAAGACACCATC
CAGGGGGTACCTCTGTCCTCATACATATCCATCAACTCAGACACTGGCGTCCTGTATGCA
CTCAGATCCTTCGACTATGAGCAGTTTCATGAGCTACAGATGCAGGTGACAGCCAGCGAC
AGCGGGGATCCTCCACTCAGCAGCAACGTGTCGTTGAGCCTGTTTGTGCTGGACCAGAAC
GACAATGCGCCCGAGATCCTGTACCCCGCCCTCCCCACAGACGGTTCCACAGGCGTGGAG
CTGGCGCCCCGCTCCGCAGAGCCCGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACAGA
GACTCCGGCCAGAACGCCTGGCTGTCCTACCGTCTGCTCAAGGCCAGCGAGCCGGGACTC
TTCGCGGTGGGGGAGCACACGGGCGAGGTGCGCACGGCGCGAGCCCTGCTGGACAGAGAC
GCGCTCAAGCAAAGCCTCGTAGTGGCCGTCCAGGACCACGGCCAGCCCCCTCTCTCCGCC
ACTGTCACGCTCACCGTGGCCGTGGCCGACAGCATCCCCCAAGTCCTGGCGGACCTCGGC
AGCTTCGAGTCTCCAGCTAACTCTGAAACCTCAGACCTCACTCTGTACCTGGTGGTAGCG
GTGGCCGCGGTCTCCTGCGTCTTCCTGGCCTTCGTCATCGTGCTGCTGGCGCACAGGCTG
CGGCGCTGGCACAAGTCACGCCTGCTGCAGGCTTCAGGAGGCGGCTTGACAGGTGTGTCC
GGCTCGCACTTTGTGGGCGTGGACGGGGTTCGGGCTTTCCTGCAGACCTATTCCCACGAG
GTCTCTCTCACCGCGGACTCGCGAAAGAGTCACCTGATCTTCCCCCAGCCCAATTATGCG
GACACGCTCATCAGCCAGGAGAGCTGTGAGAAAAACGATCCTTTGTCTTTGTTAGATGAT
TCGAAGTTTCCTATAGAGGATACCCCATTGGTTCCACAAGCCCCGCCCAACACGGACTGG
CGTTTCTCTCAGGCCCAGAGACCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGC
ACCTGGCCCAACAACCAGTTTGACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCC
AGTGAAGCTGCTGATGGGAGCTCCACCCTGGGAGGGGGTGCCGGCACCATGGGATTGAGC
GCCCGCTACGGACCCCAGTTCACCCTGCAGCACGTGCCCGACTACCGCCAGAATGTCTAC
ATCCCAGGCAGCAATGCCACACTGACCAACGCAGCTGGCAAGCGGGATGGCAAGGCCCCA
GCAGGTGGCAATGGCAACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 936 |
| Molecular Weight
| 101445.5 |
| Theoretical pI
| 4.53 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin gamma-A10
MAAQRNRSKESKDCSGLVLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLAP
RELAERGVRIVSRGRTQLFSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKL
FGIEIEVTDINDNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNK
HFSLRVQSRANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDAN
DNAPVFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLKFQLNK
YTGEIKISENLDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPV
TEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVS
SYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTA
LDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASD
SGDPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDR
DSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSA
TVTLTVAVADSIPQVLADLGSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRL
RRWHKSRLLQASGGGLTGVSGSHFVGVDGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYA
DTLISQESCEKNDPLSLLDDSKFPIEDTPLVPQAPPNTDWRFSQAQRPGTSGSQNGDDTG
TWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVY
IPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
|
| External Links |
|---|
| GenBank ID Protein
| 5456926 |
| UniProtKB/Swiss-Prot ID
| Q9Y5H3 |
| UniProtKB/Swiss-Prot Entry Name
| PCDGA_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152319 |
| GeneCard ID
| PCDHGA10 |
| GenAtlas ID
| PCDHGA10 |
| HGNC ID
| HGNC:8697 |
| References |
|---|
| General References
| - Wu Q, Maniatis T: A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell. 1999 Jun 11;97(6):779-90. [PubMed:10380929 ]
|
