Human Metabolome Database: Showing Protein Protein piccolo (HMDBP07933)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 metabolite

Identification

HMDB Protein ID

HMDBP07933

Secondary Accession Numbers

13644

Name

Protein piccolo

Synonyms

Aczonin

Gene Name

PCLO

Protein Type

Unknown

Biological Properties

General Function

Involved in transporter activity

Specific Function

May act as a scaffolding protein involved in the organization of synaptic active zones and in synaptic vesicle trafficking

Pathways

Not Available

Reactions

Not Available

GO Classification

Component
cytoplasmic vesicle
cytoplasmic membrane-bounded vesicle
coated vesicle
clathrin-coated vesicle
synaptic vesicle
membrane
cell part
synapse
organelle
vesicle
Function
ion binding
cation binding
metal ion binding
binding
transition metal ion binding
zinc ion binding
transporter activity
Process
establishment of localization
transport

Cellular Location

Cell junction
synapse

Gene Properties

Chromosome Location

Chromosome:7

Locus

7q11.23-q21.3

SNPs

PCLO

Gene Sequence

>15429 bp
ATGGGCAACGAGGCGAGCTTGGAAGGGGAAGGGCTCCCCGAAGGGCTGGCGGCGGCCGCA
GCGGCTGGAGGAGGAGCTAGCGGGGCGGGGAGCCCCTCTCACACCGCGATCCCGGCCGGC
ATGGAGGCGGATTTGAGCCAGCTGAGCGAAGAGGAGAGGAGACAGATCGCCGCTGTCATG
TCAAGGGCGCAGGGGCTGCCCAAGGGAAGCGTCCCCCCGGCCGCTGCGGAGTCGCCTTCC
ATGCACAGGAAACAAGAGTTGGATAGTAGTCATCCTCCAAAGCAATCAGGAAGACCCCCG
GACCCTGGGCGTCCAGCTCAACCTGGTCTCAGTAAAAGTAGAACTACAGACACTTTCAGG
TCAGAGCAGAAATTGCCTGGGAGGAGTCCTTCCACTATTAGCTTGAAAGAATCAAAGTCC
AGAACTGATTTAAAGGAAGAGCACAAGTCTAGTATGATGCCTGGCTTCCTCTCAGAGGTT
AACGCTTTAAGTGCTGTTTCCTCTGTTGTAAATAAATTCAACCCTTTTGATTTGATATCA
GACTCTGAGGCATCCCAGGAAGAAACCACCAAGAAACAAAAAGTGGTTCAGAAGGAGCAA
GGAAAACCTGAAGGAATCATAAAACCTCCTTTACAACAACAGCCACCCAAGCCGATTCCT
AAGCAGCAAGGACCTGGTAGGGATCCGCTTCAGCAGGATGGCACTCCCAAATCAATATCT
TCTCAACAACCAGAAAAAATTAAATCACAACCTCCAGGTACAGGAAAGCCAATTCAGGGT
CCTACCCAGACTCCTCAGACAGACCATGCAAAATTGCCACTTCAACGAGATGCATCCAGG
CCTCAGACTAAACAGGCAGACATAGTAAGGGGAGAATCAGTTAAACCCTCACTGCCAAGC
CCATCCAAACCACCTATTCAGCAACCAACTCCTGGAAAACCTCCAGCACAGCAGCCTGGA
CATGAAAAATCACAGCCTGGGCCTGCAAAGCCCCCAGCTCAGCCCTCAGGGCTAACAAAG
CCATTGGCTCAACAACCAGGGACAGTGAAACCCCCAGTCCAGCCACCAGGGACAACAAAG
CCTCCAGCTCAGCCTCTTGGTCCTGCTAAGCCTCCAGCTCAGCAGACTGGGTCAGAGAAG
CCTTCATCGGAGCAGCCTGGGCCAAAGGCTTTAGCTCAGCCTCCTGGAGTTGGAAAGACT
CCAGCTCAACAGCCAGGGCCAGCAAAGCCTCCAACCCAGCAGGTGGGGACACCAAAACCC
CTAGCTCAACAACCTGGGCTACAGTCTCCAGCTAAGGCACCTGGGCCTACAAAGACTCCA
GTTCAGCAGCCTGGGCCAGGAAAGATTCCAGCTCAACAGGCAGGACCCGGAAAGACTTCT
GCCCAGCAGACTGGCCCAACAAAGCCTCCTTCACAACTGCCTGGCCCAGCAAAGCCCCCA
CCTCAACAGCCTGGCCCAGCAAAGCCCCCACCTCAACAGCCTGGCTCAGCAAAGCCCCCA
TCTCAACAGCCTGGCTCAACAAAACCCCCACCTCAACAGCCTGGCCCAGCAAAGCCCTCA
CCTCAACAGCCTGGCTCAACAAAACCCCCATCTCAACAGCCTGGCTCAGCAAAACCCTCA
GCTCAACAGCCTAGCCCAGCAAAGCCCTCGGCTCAGCAATCTACAAAACCAGTAAGCCAA
ACAGGATCTGGAAAACCTCTGCAGCCACCAACAGTGTCTCCATCTGCAAAACAGCCTCCT
TCACAAGGCCTCCCTAAAACCATCTGTCCTCTTTGCAATACCACTGAACTTCTGTTGCAT
GTTCCAGAAAAGGCCAATTTTAACACATGCACTGAGTGTCAAACCACTGTCTGTAGTCTC
TGTGGTTTTAATCCCAATCCTCATTTAACGGAGGTAAAAGAGTGGCTCTGTTTGAACTGT
CAAATGAAAAGAGCTCTAGGCGGGGATCTGGCTCCAGTTCCGTCATCACCCCAGCCCAAA
CTGAAGACTGCACCTGTTACCACTACATCAGCAGTGAGCAAATCATCCCCACAGCCACAG
CAGACTTCCCCAAAGAAGGATGCTGCACCAAAACAGGATCTCTCCAAGGCACCTGAGCCT
AAAAAGCCACCACCACTAGTGAAACAACCAACCCTTCATGGCTCTCCTTCAGCCAAGGCC
AAGCAGCCCCCTGAGGCAGATTCTTTGTCCAAGCCAGCCCCTCCCAAAGAACCTTCTGTC
CCATCTGAGCAGGACAAGGCCCCTGTTGCTGATGATAAACCAAAGCAGCCCAAGATGGTA
AAGCCAACCACTGACCTTGTATCTTCATCATCAGCAACAACAAAACCTGATATTCCAAGC
TCCAAAGTACAGTCACAAGCTGAAGAGAAAACAACCCCTCCTCTAAAAACAGACTCTGCC
AAACCCTCACAGAGTTTTCCACCAACAGGGGAAAAAGTCAGCCCATTTGATTCTAAAGCC
ATACCTCGACCTGCATCAGATTCAAAAATTATTTCACATCCTGGTCCCAGTTCAGAGAGC
AAAGGTCAAAAACAAGTTGACCCCGTACAAAAGAAGGAAGAACCCAAGAAAGCACAAACC
AAAATGAGTCCTAAACCAGATGCCAAGCCAATGCCAAAAGGGTCACCAACACCCCCTGGC
CCACGACCTACCGCTGGCCAAACTGTCCCCACACCTCAACAGTCCCCAAAGCCTCAGGAG
CAGTCAAGGCGTTTCAGTCTGAATCTGGGAAGTATTACTGATGCCCCCAAATCACAGCCT
ACAACTCCTCAAGAGACCGTGACTGGGAAACTCTTTGGGTTTGGAGCATCAATCTTCAGC
CAGGCATCAAATTTAATTTCCACTGCAGGCCAACCTGGACCTCATTCACAAAGTGGACCA
GGGGCCCCAATGAAACAAGCCCCTGCCCCTTCACAGCCACCTACTTCACAAGGGCCACCC
AAATCCACAGGTCAAGCACCACCAGCACCTGCAAAAAGTATACCTGTGAAAAAGGAAACA
AAAGCCCCAGCAGCTGAAAAATTAGAGCCCAAAGCTGAACAAGCTCCAACAGTAAAAAGA
ACAGAAACAGAAAAAAAGCCACCACCTATTAAGGATAGCAAATCTTTAACAGCTGAGCCT
CAAAAGGCTGTCCTTCCCACAAAACTGGAGAAATCGCCCAAACCAGAATCAACCTGTCCT
CTCTGCAAAACTGAACTCAACATAGGTTCTAAGGATCCTCCTAACTTCAATACTTGCACT
GAATGCAAGAATCAAGTGTGTAATCTCTGTGGATTTAACCCTACACCACATTTGACTGAG
ATTCAAGAATGGCTTTGTTTAAATTGCCAAACCCAGAGAGCAATATCAGGACAGCTTGGA
GACATACGCAAAATGCCACCTGCACCATCAGGACCCAAAGCATCTCCTATGCCTGTTCCT
ACAGAATCATCATCTCAGAAAACAGCAGTGCCTCCCCAAGTAAAATTAGTGAAAAAGCAA
GAACAAGAAGTAAAAACGGAAGCTGAAAAAGTCATTCTGGAAAAAGTAAAGGAAACACTA
TCAATGGAAAAAATTCCTCCTATGGTAACCACAGATCAAAAACAAGAAGAGAGTAAACTA
GAGAAAGACAAAGCTTCAGCTCTTCAAGAAAAAAAGCCACTCCCTGAAGAAAAAAAACTA
ATCCCTGAAGAAGAAAAGATACGTTCTGAAGAAAAAAAGCCACTCCTAGAAGAAAAAAAG
CCAACCCCTGAAGACAAAAAGCTACTCCCAGAGGCAAAAACATCAGCCCCAGAAGAACAG
AAACATGACTTACTTAAATCTCAAGTACAAATTGCTGAAGAAAAGCTTGAAGGCAGAGTG
GCTCCAAAGACAGTGCAAGAAGGGAAACAACCACAGACCAAGATGGAAGGTTTACCATCT
GGCACACCTCAGAGTTTACCTAAAGAAGATGATAAGACAACCAAAACAATAAAAGAACAG
CCACAGCCACCATGCACAGCAAAACCTGATCAGGTGGAACCTGGGAAAGAAAAAACAGAA
AAGGAAGATGACAAATCAGACACCTCAAGTTCTCAGCAGCCTAAAAGCCCCCAAGGTCTG
AGCGACACGGGATATTCTTCCGATGGAATATCAAGCTCACTTGGTGAAATTCCAAGTCTT
ATTCCAACTGATGAAAAGGATATTCTCAAGGGACTCAAAAAGGACTCTTTTTCACAAGAA
AGCAGCCCTTCCAGCCCCTCAGATTTGGCTAAGTTAGAAAGTACAGTCCTATCTATTTTG
GAAGCTCAAGCAAGTACACTTGCTGATGAAAAGTCAGAAAAGAAAACACAACCCCATGAA
GTTTCTCCTGAACAGCCTAAAGACCAAGAGAAAACTCAGAGTTTATCTGAAACCTTGGAA
ATTACTATTTCAGAAGAGGAGATCAAAGAGAGTCAAGAAGAAAGGAAAGACACTTTTAAA
AAAGATAGCCAACAAGATATTCCTTCCAGCAAGGACCATAAAGAGAAGTCTGAGTTTGTT
GATGACATAACTACTAGAAGAGAGCCTTATGATTCAGTTGAAGAGAGTAGTGAAAGTGAA
AACTCACCTGTTCCACAAAGAAAACGAAGAACTAGTGTTGGCTCATCAAGCAGTGATGAG
TATAAACAGGAAGACAGCCAAGGATCAGGGGAAGAGGAGGACTTCATTCGAAAACAAATC
ATAGAAATGAGTGCTGATGAAGATGCTTCAGGTTCTGAAGATGATGAGTTCATCAGAAAC
CAGCTCAAAGAGATTAGTAGCAGTACTGAGAGCCAGAAGAAGGAAGAAACAAAGGGAAAA
GGCAAAATAACAGCAGGGAAACACAGACGACTGACTCGAAAAAGTAGCACAAGCATTGAT
GAAGATGCAGGAAGACGTCACTCATGGCATGATGAAGACGATGAAGCATTTGATGAAAGT
CCTGAACTTAAATACAGAGAAACTAAAAGTCAGGAAAGTGAAGAACTTGTAGTTACTGGA
GGAGGAGGGCTACGCCGATTTAAAACAATTGAGCTCAACAGTACAATAGCAGATAAATAT
TCTGCAGAGTCATCACAGAAAAAAACAAGTTTGTATTTTGACGAAGAGCCAGAATTGGAA
ATGGAAAGCCTGACAGACTCACCTGAAGATAGGTCAAGGGGAGAGGGATCTTCGAGTCTG
CATGCTTCCAGCTTCACTCCTGGTACATCCCCTACATCAGTATCATCACTTGATGAGGAC
AGTGACAGTAGCCCGAGTCACAAAAAAGGAGAGAGCAAACAGCAACGCAAAGCTCGGCAC
AGACCACATGGCCCTCTTTTGCCTACTATTGAAGATTCTTCAGAGGAAGAAGAATTGAGA
GAGGAAGAAGAATTATTAAAGGAGCAAGAAAAGCAGAGGGAAATAGAACAGCAACAAAGA
AAGAGTTCTAGTAAAAAATCAAAGAAAGACAAAGATGAACTTCGAGCTCAGAGAAGAAGG
GAAAGGCCAAAGACACCACCTAGTAATCTCTCTCCCATTGAAGATGCATCTCCGACAGAA
GAGTTACGTCAGGCTGCAGAAATGGAGGAGCTCCATAGATCTTCTTGTTCTGAATATTCA
CCTAGCATAGAGTCAGACCCAGAAGGTTTTGAAATAAGCCCGGAAAAAATAATAGAAGTA
CAAAAAGTTTATAAATTGCCCACAGCTGTTTCATTATACTCACCAACAGATGAGCAATCT
ATTATGCAGAAAGAAGGTAGCCAAAAGGCGTTAAAAAGTGCTGAGGAGATGTATGAAGAA
ATGATGCATAAAACACACAAATACAAAGCTTTTCCAGCTGCAAATGAACGAGATGAAGTG
TTTGAAAAAGAGCCTTTGTATGGTGGGATGCTAATAGAGGATTATATTTATGAATCTTTA
GTAGAAGACACGTACAATGGATCGGTAGATGGCAGTCTGCTAACAAGGCAAGAAGAAGAA
AATGGATTTATGCAGCAGAAAGGAAGAGAGCAAAAGATAAGACTTTCAGAACAGATTTAT
GAAGATCCTATGCAGAAAATTACAGACCTCCAGAAAGAGTTTTATGAGTTAGAAAGCTTA
CATTCTGTTGTGCCTCAGGAAGATATTGTTTCAAGCTCTTTTATCATCCCAGAAAGCCAT
GAGATAGTGGACCTGGGTACTATGGTAACTTCTACAGAAGAAGAAAGGAAACTACTAGAT
GCTGATGCTGCCTATGAAGAACTTATGAAGAGGCAACAGATGCAATTAACACCTGGATCT
AGCCCAACCCAGGCCCCCATTGGTGAGGATATGACAGAGTCCACCATGGACTTTGACAGA
ATGCCAGATGCCTCTTTGACATCAAGTGTTCTCTCAGGAGCGTCTCTTACAGATTCGACC
AGCAGTGCAACACTCTCTATCCCAGATGTTAAAATAACCCAACATTTTTCAACAGAAGAA
ATTGAGGATGAATATGTAACCGATTATACAAGAGAAATTCAAGAGATAATTGCCCATGAA
TCGCTGATTTTGACCTACTCGGAGCCTTCAGAAAGTGCTACATCTGTCCCACCCTCTGAC
ACACCTTCTCTCACATCATCTGTTTCTTCGGTCTGTACCACAGATAGCTCTTCACCCATT
ACTACCCTGGATAGCATAACCACAGTTTATACAGAGCCAGTGGACATGATAACTAAATTT
GAAGATTCTGAGGAAATTTCTTCATCAACTTATTTTCCAGGCAGCATTATAGACTATCCA
GAAGAAATAAGTGTATCTTTAGATCGGACTGCCCCACCAGATGGTAGAGCTAGTGCTGAT
CATATTGTTATTTCCTTATCTGATATGGCATCTTCTATCATAGAATCTGTAGTACCTAAA
CCTGAAGGGCCAGTTGCTGACACTGTTTCTACTGACTTACTTATATCTGAAAAGGACCCA
GTGAAGAAAGCCAAGAAGGAAACTGGGAATGGAATCATTCTGGAAGTTTTGGAAGCTTAC
AGAGATAAAAAGGAGTTGGAGGCCGAACGAACAAAAAGTAGCTTATCCGAAACCGTGTTT
GATCACCCACCTTCTTCTGTAATAGCCCTTCCAATGAAAGAGCAGCTTTCAACTACATAC
TTTACATCTGGAGAGACCTTTGGTCAGGAAAAACCTGCATCTCAGTTACCATCTGGCAGT
CCTTCTGTTTCCTCTCTTCCAGCTAAACCTCGCCCATTCTTTAGAAGTTCTTCTTTGGAT
ATATCAGCTCAACCTCCTCCCCCTCCTCCCCCTCCCCCTCCTCCTCCTCCTCCACCACCA
CCCCCTCCTCCCCCACCACTTCCTCCACCAACTTCACCTAAACCAACTATTCTTCCTAAA
AAAAAGTTAACAGTTGCATCTCCAGTGACTACAGCTACACCTCTGTTTGATGCTGTTACT
ACTCTAGAGACCACAGCTGTTCTGAGAAGTAATGGATTACCTGTTACAAGAATATGTACT
ACTGCACCTCCTCCTGTTCCTCCTAAGCCATCTTCAATTCCATCTGGACTTGTATTTACC
CACAGGCCTGAGCCAAGCAAACCTCCAATCGCCCCCAAACCAGTGATTCCTCAGCTTCCA
ACAACTACACAAAAACCAACAGATATACACCCCAAACCAACAGGCCTATCTTTAACTTCA
AGTATGACCTTAAATTTAGTGACTTCAGCAGATTATAAATTGCCTTCCCCTACCTCCCCA
CTTTCCCCACACTCCAACAAGTCTTCACCAAGATTTTCCAAATCCCTCACAGAAACTTAT
GTAGTTATTACATTGCCATCTGAACCAGGGACTCCAACAGATTCTTCTGCTAGTCAAGCA
ATTACCAGTTGGCCCTTGGGATCACCCTCCAAAGATCTGGTTTCTGTTGAACCTGTGTTT
TCTGTAGTTCCTCCTGTGACAGCTGTAGAAATTCCAATTTCTTCAGAACAGACCTTCTAC
ATCTCTGGAGCTTTACAGACATTTTCTGCTACCCCTGTCACAGCACCCTCTTCATTTCAA
GCAGCTCCCACATCAGTTACACAGTTTCTCACTACTGAAGTTTCCAAGACTGAGGTTTCA
GCAACCAGAAGTACAGCTCCTAGTGTTGGTCTCAGCAGCATTTCCATAACAATTCCTCCA
GAGCCTCTTGCTCTAGATAACATACATTTAGAGAAGCCTCAGTATAAAGAAGATGGAAAA
TTGCAACTTGTTGGTGATGTAATTGATTTGCGTACAGTACCAAAGGTAGAAGTTAAAACA
ACTGATAAATGTATTGATCTTTCTGCTTCTACAATGGATGTGAAAAGGCAGATCACAGCA
AATGAAGTTTATGGGAAACAAATTAGTGCTGTCCAACCCTCTATTATAAATCTTAGTGTG
ACATCATCAATAGTGACTCCTGTATCTCTGGCCACTGAGACAGTGACCTTTGTCACATGC
ACAGCTAGTGCAAGTTACACTACAGGCACAGAAAGCCTAGTGGGTGCAGAACATGCAATG
ACAACACCACTCCAACTTACAACATCAAAGCATGCTGAGCCCCCATACAGGATACCAAGT
GACCAGGTCTTTCCTATAGCTAGGGAAGAAGCACCAATAAACTTATCTCTAGGTACTCCA
GCACATGCAGTGACATTGGCTATTACAAAACCTGTCACTGTGCCTCCTGTTGGTGTCACA
AATGGATGGACTGATAGCACCGTATCCCAGGGAATCACTGATGGGGAAGTAGTGGATCTC
AGTACAACCAAGTCTCACAGAACAGTCGTAACAATGGATGAGTCTACTTCAAGTGTGATG
ACCAAAATAATAGAAGATGAAAAACCCGTTGATTTAACCGCAGGGAGAAGAGCTGTGTGC
TGTGATGTGGTTTATAAATTACCATTTGGAAGGAGCTGCACAGCACAGCAGCCTGCAACT
ACTCTTCCTGAGGATCGTTTTGGTTATAGGGATGACCACTATCAGTATGATCGATCAGGG
CCATATGGTTATAGAGGGATTGGGGGAATGAAGCCTTCCATGTCTGACACAAATTTAGCA
GAAGCTGGACATTTTTTCTATAAAAGTAAGAATGCTTTTGATTATTCTGAAGGAACTGAC
ACAGCAGTAGATCTGACTTCAGGGAGAGTTACTACAGGTGAGGTAATGGATTATTCAAGC
AAGACTACAGGTCCATATCCAGAAACACGACAAGTCATTTCAGGAGCTGGGATTAGTACC
CCACAGTATTCCACAGCAAGAATGACACCACCACCAGGACCCCAGTATTGTGTGGGGAGT
GTTTTGAGGTCATCTAATGGTGTTGTCTATTCTTCAGTAGCAACTCCAACACCCTCTACA
TTTGCTATCACCACACAACCTGGCTCCATTTTCAGCACCACAGTGAGGGATTTGTCTGGT
ATTCATACGGCTGATGCAGTGACTTCATTACCTGCCATGCACCATAGCCAGCCAATGCCT
AGATCATATTTTATAACAACAGGTGCATCTGAAACGGACATTGCAGTAACTGGTATTGAT
ATCAGTGCCAGTTTGCAAACTATTACTATGGAGTCTCTTACTGCTGAGACGATAGACTCT
GTTCCCACTTTAACCACAGCATCCGAAGTGTTTCCTGAAGTGGTGGGAGATGAAAGTGCT
CTTTTAATTGTCCCTGAAGAAGATAAACAACAGCAGCAGCTAGACTTGGAGCGTGAGCTC
CTGGAACTGGAGAAAATTAAGCAACAGCGCTTTGCTGAGGAATTGGAGTGGGAACGTCAG
GAAATTCAAAGGTTCCGAGAACAAGAAAAGATCATGGTTCAGAAAAAGTTGGAGGAGCTG
CAGTCTATGAAGCAACACCTTCTCTTTCAGCAAGAAGAAGAGCGGCAAGCCCAGTTCATG
ATGAGGCAGGAGACGTTAGCTCAGCAACAGTTACAGCTTGAGCAGATCCAACAGCTGCAA
CAACAGCTTCACCAGCAGCTGGAGGAGCAAAAGATTCGGCAGATCTACCAGTATAACTAT
GACCCTTCTGGAACTGCTTCTCCACAAACCACTACAGAGCAGGCAATTTTGGAAGGTCAG
TATGCTGCTCTGGAAGGCAGTCAATTTTGGGCAACTGAAGATGCAACCACCACAGCTTCA
GCTGTTGTGGCAATTGAAATACCACAAAGCCAAGGATGGTACACCGTTCAGTCTGATGGT
GTTACTCAGTACATTGCCCCACCTGGTATCCTGAGCACTGTTTCAGAAATACCTCTAACA
GATGTTGTTGTGAAAGAGGAAAAACAACCCAAAAAGAGAAGTTCTGGAGCTAAAGTCCGA
GGACAGTATGATGACATGGGAGAAAATATGACAGATGATCCCCGAAGTTTTAAAAAGATA
GTGGACAGTGGTGTACAAACGGATGACGAAGATGCCACAGATCGGAGCTATGTGAGTAGG
AGAAGGAGAACTAAAAAGAGTGTGGATACAAGCGTCCAAACTGATGATGAAGATCAGGAT
GAGTGGGATATGCCTACTAGATCAAGGAGGAAAGCTCGTGTAGGGAAATATGGTGACAGC
ATGACAGAGGCTGACAAGACCAAACCCCTTTCCAAAGTCTCCAGCATAGCAGTTCAAACG
GTAGCAGAGATATCTGTGCAAACTGAACCAGTTGGAACCATAAGAACACCCTCCATACGG
GCACGAGTGGATGCCAAGGTAGAAATAATTAAACACATTTCAGCACCTGAAAAGACTTAC
AAAGGGGGCAGTTTAGGATGTCAAACAGAAGCAGATTCAGACACACAAAGTCCTCAATAT
CTGAGTGCCACATCTCCACCCAAAGACAAGAAACGCCCAACACCTTTAGAGATTGGTTAT
TCATCTCACCTCCGGGCAGATTCCACAGTACAGCTGGCTCCTTCCCCACCCAAATCCCCC
AAAGTCCTTTACTCACCCATCTCACCACTTTCACCAGGCAAAGCCTTAGAATCAGCCTTT
GTACCTTATGAAAAACCCCTCCCTGATGATATAAGTCCACAGAAAGTACTGCATCCAGAT
ATGGCTAAAGTTCCCCCAGCAAGTCCTAAGACAGCCAAGATGATGCAGCGTTCTATGTCT
GACCCCAAGCCTCTGAGTCCAACAGCAGACGAAAGTTCCAGGGCTCCTTTTCAGTATACC
GAGGGCTATACGACTAAAGGTTCTCAAACCATGACATCCTCTGGAGCCCAGAAAAAAGTT
AAAAGAACTCTGCCAAATCCACCTCCTGAGGAGATTTCCACAGGAACTCAATCCACATTC
AGCACAATGGGCACAGTTTCCAGGAGAAGGATCTGCAGAACCAACACAATGGCACGAGCC
AAGATTCTCCAGGACATAGACAGAGAGCTTGATCTTGTGGAAAGGGAGTCTGCAAAACTT
CGAAAGAAACAAGCAGAGCTTGATGAAGAAGAAAAGGAGATTGATGCTAAGCTACGATAC
CTGGAAATGGGAATTAACAGGAGGAAAGAGGCCCTATTAAAGGAGAGAGAAAAGAGAGAA
CGAGCCTACCTCCAGGGAGTAGCTGAGGATCGTGATTACATGTCTGACAGTGAAGTGAGT
AGCACAAGACCAACCCGAATAGAAAGTCAGCATGGCATTGAGCGACCAAGAACTGCTCCC
CAAACTGAATTCAGCCAGTTTATACCACCACAAACCCAAACAGAATCTCAACTAGTTCCT
CCGACAAGTCCTTACACACAATACCAGTACTCTTCCCCTGCTCTTCCTACCCAAGCACCC
ACCTCATACACTCAACAGTCTCATTTTGAGCAACAAACTTTGTACCATCAGCAAGTTTCA
CCTTATCAGACTCAGCCAACATTCCAAGCTGTGGCAACAATGTCCTTCACACCTCAAGTT
CAACCTACACCAACCCCACAGCCTTCTTATCAGTTACCTTCACAGATGATGGTGATACAA
CAGAAGCCACGGCAAACTACATTATATTTGGAGCCCAAGATAACCTCAAACTATGAAGTG
ATTCGCAACCAACCCCTTATGATAGCACCTGTTTCTACGGATAACACATTTGCTGTTTCC
CATCTTGGTAGTAAGTACAATAGTTTAGACTTGAGAATAGGTTTGGAGGAAAGAAGTAGC
ATGGCAAGCAGTCCAATATCAAGCATATCTGCAGATTCTTTCTATGCAGATATTGATCAC
CATACTCCACGAAATTATGTCCTAATTGACGACATTGGAGAGATCACCAAAGGAACAGCG
GCATTAAGCACCGCATTTAGCCTTCATGAAAAGGATCTGTCAAAAACAGACCGTCTCCTT
CGAACCACTGAGACACGCCGGTCTCAAGAAGTGACAGATTTCCTAGCACCTTTACAGTCT
TCCTCTAGATTGCATAGTTATGTGAAGGCGGAGGAAGACCCAATGGAGGATCCTTACGAG
TTAAAGCTTCTGAAACATCAGATTAAACAGGAATTTCGTAGAGGGACAGAGAGCTTAGAT
CACCTTGCTGGTCTTTCTCATTATTACCATGCTGATACTAGCTACAGACATTTTCCAAAA
TCTGAGAAGTATAGCATCAGTAGACTCACACTTGAAAAACAAGCAGCAAAACAACTGCCA
GCAGCCATACTTTATCAAAAGCAGTCAAAGCATAAGAAATCACTAATTGACCCTAAAATG
TCAAAATTTTCACCTATTCAAGAAAGTAGAGACCTTGAACCTGATTATTCAAGCTATATG
ACTTCTAGCACTTCATCTATTGGTGGCATTTCCTCCAGGGCAAGGCTCCTTCAAGATGAC
ATCACTTTTGGCCTCAGAAAAAATATTACAGACCAACAAAAATTTATGGGATCTTCTCTT
GGCACAGGACTGGGCACATTAGGAAATACCATACGCTCAGCTCTGCAGGATGAAGCGGAT
AAGCCATACAGTAGTGGCAGCAGGTCCAGACCTTCCTCCAGACCTTCCTCTGTCTATGGG
CTTGATTTATCAATTAAAAGGGATTCTTCTAGCTCTTCCCTAAGACTGAAAGCTCAAGAG
GCTGAAGCTCTAGATGTTTCCTTTAGTCATGCATCATCCTCTGCCAGAACTAAGCCGACC
AGTTTGCCAATTAGTCAAAGTAGAGGAAGAATACCAATTGTGGCCCAGAATTCTGAAGAA
GAAAGCCCACTCAGTCCTGTTGGCCAGCCAATGGGAATGGCCAGGGCTGCAGCTGGACCC
CTGCCACCAATATCTGCAGACACCAGGGATCAGTTTGGATCAAGCCACTCATTGCCTGAA
GTTCAGCAACACATGAGGGAAGAATCACGGACTCGAGGCTATGACCGTGACATAGCATTC
ATCATGGATGACTTCCAACATGCCATGTCAGACAGTGAAGCCTATCATCTGCGTCGTGAG
GAAACAGATTGGTTTGATAAACCCAGGGAGTCTCGTTTGGAAAATGGACATGGTCTGGAC
CGAAAACTGCCGGAAAGATTGGTCCACTCTAGACCACTCAGTCAACATCAAGAGCAAATT
ATACAGATGAACGGGAAAACTATGCACTACATCTTTCCTCACGCAAGGATAAAAATAACA
AGAGACTCAAAGGATCACACAGTTTCAGGTAATGGATTAGGAATTAGAATTGTGGGTGGT
AAAGAAATCCCGGGACATAGTGGAGAAATTGGAGCCTATATTGCCAAGATTCTTCCTGGG
GGAAGTGCGGAACAGACGGGGAAGCTTATGGAAGGGATGCAAGTATTGGAATGGAATGGA
ATTCCCTTGACTTCTAAAACATATGAAGAAGTTCAGAGTATCATTAGTCAGCAAAGTGGG
GAAGCAGAAATATGTGTAAGACTGGACCTCAATATGCTATCAGATTCTGAAAATTCCCAG
CATCTGGAACTTCATGAGCCACCAAAAGCTGTGGATAAGGCGAAATCCCCAGGGGTTGAT
CCTAAGCAGTTGGCAGCAGAACTCCAGAAGGTTTCACTACAGCAGTCACCGCTGGTTCTG
TCATCAGTTGTTGAAAAAGGATCTCATGTTCATTCAGGTCCTACATCAGCAGGATCCAGT
TCCGTTCCCAGCCCTGGGCAACCAGGGTCCCCCTCAGTGAGCAAAAAGAAGCACGGCAGC
AGCAAGCCTACCGATGGAACAAAGGTTGTCTCTCATCCAATTACAGGAGAAATTCAGCTT
CAAATTAACTATGATCTTGGAAATCTCATAATACATATTCTCCAAGCAAGAAATCTTGTT
CCTCGAGACAACAATGGTTATTCTGACCCTTTTGTGAAAGTGTACCTTCTTCCAGGGAGA
GGTCAAGTCATGGTTGTCCAGAATGCAAGTGCTGAGTACAAGAGAAGGACTAAACATGTC
CAGAAAAGTCTTAATCCTGAGTGGAATCAAACAGTAATTTATAAAAGTATTTCCATGGAA
CAGCTCAAGAAGAAAACACTGGAGGTGACAGTTTGGGATTATGATAGATTTTCATCCAAC
GACTTCCTTGGGGAGGTATTGATTGATTTATCTAGCACATCTCACCTCGATAACACTCCA
AGGTGGTATCCTCTCAAAGAACAGACTGAAAGCATTGATCATGGCAAGTCTCATTCCAGT
CAGAGCAGCCAGCAGTCCCCAAAGCCATCTGTTATCAAAAGCAGAAGCCATGGTATCTTC
CCTGACCCATCAAAGGACATGCAGGTTCCCACCATTGAGAAATCCCATAGTAGTCCTGGT
AGCTCAAAATCATCATCAGAAGGCCATCTCCGTTCTCATGGACCATCTCGCAGTCAAAGC
AAAACCAGCGTCACTCAGACCCACCTGGAAGATGCAGGGGCTGCCATAGCTGCTGCCGAA
GCTGCCGTGCAACAACTCCGCATTCAACCAACAAAGCCTCCCAATCACCGGCCTGCAGAA
AGCTCTGTGTCCACCGGCTCCTCGGGCAGCAGCTTTGGCAGTGGGTATAGCGTGGACAGT
GAAGGAAGCAGCAGCACTGCAGGGGAGACTAATCTATTTCCTATTCCGAGGATAGGGAAG
ATGGGACAGAATGGACAAGAGCCTGTAAAACAGCCAGGGGTAGGAGTAGGACTAGCAGAC
ACTGAAGCTAAAACTCAGGTAATGGGAGAAATCAAGATTGCATTGAAGAAGGAAATGAAG
ACAGATGGTGAACAACTAATAGTTGAAATTCTCCAATGCAGAAATATTACATACAAATTT
AAGTCTCCTGATCATCTACCAGATTTATATGTGAAAATATATGTGATGAATATTTCTACC
CAAAAAAAGGTGATCAAGAAAAAAACAAGAGTATGCAGACATGATCGAGAGCCTTCGTTT
AATGAAACTTTTCGATTCAGTCTAAGTCCTGCAGGACATTCTCTTCAGATTTTACTTTTC
TCCAATGGAGGGAAGTTTATGAAAAAGACCTTGATTGGTGAAGCCTGTATCTGGCTTGAC
AAAGTGGATCTCAGAAAAAGAATAGTCAACTGGCACAAACTTTTGGTCAGTCCTACTCAA
ACGCATTGA

Protein Properties

Number of Residues

5183

Molecular Weight

566652.3

Theoretical pI

6.49

Pfam Domain Function

C2 (PF00168 )
zf-piccolo (PF05715 )

Signals

None

Transmembrane Regions

None

Protein Sequence

>Protein piccolo
MGNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVM
SRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR
SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS
DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS
SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS
PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK
PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP
LAQQPGLQSPAKAPGPTKTPAQTKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP
GSAKPSAQQPSPAKPSAQQFTKPVSQTGFGKPLQPPTVSPSAKQPPSQGLPKTICPLCNT
TELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEAKEWLCLNCQMKRALGGDLAPVP
SSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHG
SPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT
KPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVTPFDSKAIPRPASDSKIISHP
GPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQ
SPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGP
HSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQ
APTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPP
NFNTCTECKNQVCNLCGFNPTPHLTENCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPT
ESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLE
KDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQK
HDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQP
QPPCTAKPDQEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDIL
KGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQ
EKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREP
YDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDA
SGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSW
HDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKT
SLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKK
GESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKK
DKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEG
FEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEEMMHKTHKYK
AFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEENGFMQQKGR
EQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESHEIVDLGTMV
TSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLTSS
VLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHESLILTYSEP
SESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSS
TYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTV
STDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIA
LPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPP
PPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLR
SNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDI
HPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEP
GTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFS
ATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIH
LEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQIS
AVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAMTTPLQLTTS
KHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVTNGWTDSTVS
QGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIEDEKPVDLTAGRRAVCCDVVYKLPF
GRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNLAEAGHFFYKS
KNAFDYSEGTDTAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGAGISTPQYSTARMT
PPPGPQYCVGSVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRDLSGIHTADAVTS
LPAMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMESLTAETIDSVPTLTTASE
VFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQE
KIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEE
QKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTASAVVAIEIPQ
SQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKVRGQYDDMGEN
MTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQDEWDMPTRSR
RKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEI
IKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADST
VQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASP
KTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPP
EEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKLRKKQAELDE
EEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSSTRPTRIES
QHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHF
EQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQQKPRQTTLY
LEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERSSMASSPISSI
SADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRLLRTTETRRSQ
EVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESLDHLAGLSHYY
HADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPKMSKFSPIQES
RDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSLGTGLGTLGN
TIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFS
HASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTR
DQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRREETDWFDKPR
ESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTMHYIFPHARIKITRDSKDHTVS
MQVLEWNGIPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKAVD
KAKSPGVDPKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPS
VSKKKHGSSKLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGAEYKRRTK
HVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDN
TPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSS
PGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAAEAAVQQLRIQPTAHKSGQS
NHARKQHRHSIAGVLPIQRTQSDNLPPPANGNQDQSQLALRKVMSDGPVKPEGAKPPNHR
PAESSVSTGSSGSSFGSGYSVDSEGSSSTAGETNLFPIPRIGKMGQNGQEPVKQPGVGVG
LADTEARGQREPKPGQACFLGARNMKEIQPMPEIYPETDKDGEKYPGSLFLPFSNLCQCL
IKTNWKPVDGEAQADLELLPNLQTRRILPPSMYLLQKTKALQTYKRSDIRGSNGPTINAT
TCFETTSVMGEIKIALKKEMKTDGEQLIVEILQCRNITYKFKSPDHLPDLYVKIYVMNIS
TQKKVIKKKTRVCRHDREPSFNETFRFSLSPAGHSLQILLFSNGGKFMKKTLIGEACIWL
DKVDLRKRIVNWHKLLVSPTQTH

External Links

GenBank ID Protein

150378539

UniProtKB/Swiss-Prot ID

Q9Y6V0

UniProtKB/Swiss-Prot Entry Name

PCLO_HUMAN

PDB IDs

Not Available

GenBank Gene ID

Not Available

GeneCard ID

PCLO

GenAtlas ID

PCLO

HGNC ID

HGNC:13406

References

General References

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Wang X, Kibschull M, Laue MM, Lichte B, Petrasch-Parwez E, Kilimann MW: Aczonin, a 550-kD putative scaffolding protein of presynaptic active zones, shares homology regions with Rim and Bassoon and binds profilin. J Cell Biol. 1999 Oct 4;147(1):151-62. [PubMed:10508862 ]