Showing Protein Tescalcin (HMDBP08051)

• 13762

1. CHP3
2. Calcineurin B homologous protein 3
3. TSC

1. Cytoplasm

>645 bp
ATGGGCGCTGCCCACTCCGCGTCTGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGCTTC
TCATCGGATCAGATCGAGCAGCTCCATCGGAGATTTAAGCAGCTGAGTGGAGATCAGCCT
ACCATTCGCAAGGAGAACTTCAACAATGTCCCGGACCTGGAGCTCAACCCCATCCGATCC
AAAATTGTTCGTGCCTTCTTCGACAACAGGAACCTGCGCAAGGGACCCAGTGGCCTGGCT
GATGAGATCAATTTCGAGGACTTCCTGACCATCATGTCCTACTTCCGGCCCATCGACACC
ACCATGGACGAGGAACAGGTGGAGCTGTCCCGGAAGGAGAAGCTGAGATTTCTGTTCCAC
ATGTACGACTCGGACAGCGACGGCCGCATCACTCTGGAAGAATATCGAAATGTGGTCGAG
GAGCTGCTGTCGGGAAACCCTCACATCGAGAAGGAGTCCGCTCGCTCCATCGCCGACGGG
GCCATGATGGAGGCGGCCAGCGTGTGCATGGGGCAGATGGAGCCTGATCAGGTGTACGAG
GGGATCACCTTCGAGGACTTCCTGAAGATCTGGCAGGGGATCGACATTGAGACCAAGATG
CACGTCCGCTTCCTTAACATGGAAACCATGGCCCTCTGCCACTGA

• None

• None

>Tescalcin
MGAAHSASEEVRELEGKTGFSSDQIEQLHRRFKQLSGDQPTIRKENFNNVPDLELNPIRS
KIVRAFFDNRNLRKGPSGLADEINFEDFLTIMSYFRPIDTTMDEEQVELSRKEKLRFLFH
MYDSDSDGRITLEEYRNVVEELLSGNPHIEKESARSIADGAMMEAASVCMGQMEPDQVYE
GITFEDFLKIWQGIDIETKMHVRFLNMETMALCH

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4. Mailander J, Muller-Esterl W, Dedio J: Human homolog of mouse tescalcin associates with Na(+)/H(+) exchanger type-1. FEBS Lett. 2001 Nov 2;507(3):331-5. [PubMed:11696366 ]
5. Li X, Liu Y, Kay CM, Muller-Esterl W, Fliegel L: The Na+/H+ exchanger cytoplasmic tail: structure, function, and interactions with tescalcin. Biochemistry. 2003 Jun 24;42(24):7448-56. [PubMed:12809501 ]
6. Levay K, Slepak VZ: Tescalcin is an essential factor in megakaryocytic differentiation associated with Ets family gene expression. J Clin Invest. 2007 Sep;117(9):2672-83. [PubMed:17717601 ]
7. Zaun HC, Shrier A, Orlowski J: Calcineurin B homologous protein 3 promotes the biosynthetic maturation, cell surface stability, and optimal transport of the Na+/H+ exchanger NHE1 isoform. J Biol Chem. 2008 May 2;283(18):12456-67. doi: 10.1074/jbc.M800267200. Epub 2008 Mar 5. [PubMed:18321853 ]