Hmdb loader
Identification
HMDB Protein ID HMDBP08106
Secondary Accession Numbers
  • 13817
Name A-kinase anchor protein 7 isoform gamma
Synonyms
  1. A-kinase anchor protein 18 kDa
  2. AKAP 18
  3. AKAP-7 isoform gamma
  4. Protein kinase A-anchoring protein 7 isoform gamma
Gene Name AKAP7
Protein Type Unknown
Biological Properties
General Function Involved in catalytic activity
Specific Function Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures
Pathways Not Available
Reactions Not Available
GO Classification
Component
cell part
intracellular
Function
catalytic activity
Process
rna metabolic process
metabolic process
macromolecule metabolic process
cellular macromolecule metabolic process
Cellular Location
  1. Cytoplasm
Gene Properties
Chromosome Location Chromosome:6
Locus 6q23
SNPs AKAP7
Gene Sequence
>981 bp
ATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACT
GTAGATATTCAGGATGACTGTGGAATCACTGATGAACCTCAAATAAATTTGAAGAGAAGT
CAAGAAAATGAATGGGTCAAGAGTGATCAAGTAAAGAAGAGGAAAAAAAAGAGAAAAGAT
TATCAACCCAACTATTTCCTGTCCATTCCAATCACCAACAAAGAGATTATAAAAGGAATT
AAGATCCTGCAGAATGCAATAATACAACAAGATGAGCGACTGGCCAAAGCAATGGTCAGT
GATGGTTCCTTTCATATTACCCTGCTGGTGATGCAATTATTAAATGAAGATGAAGTAAAC
ATTGGTATTGATGCTCTTTTGGAATTGAAACCATTCATAGAAGAACTCCTCCAGGGAAAA
CATTTGACTTTGCCCTTTCAAGGGATTGGTACTTTTGGAAATCAGGTTGGATTTGTGAAG
CTGGCAGAAGGAGATCATGTAAACTCACTTTTGGAGATAGCAGAGACTGCAAATAGGACA
TTTCAAGAAAAAGGCATCCTGGTAGGAGAGAGCAGAAGTTTTAAACCTCATTTGACCTTC
ATGAAGTTGTCAAAATCACCGTGGCTCCGTAAGAATGGAGTGAAAAAAATAGATCCTGAT
TTATATGAAAAGTTTATCAGTCACAGATTTGGAGAAGAAATATTATATCGCATAGATCTT
TGCTCCATGCTGAAGAAAAAACAAAGTAATGGTTATTATCACTGTGAATCTTCCATTGTG
ATTGGTGAAAAGAACGGAGGGGAGCCCGATGACGCTGAACTAGTAAGGCTCAGTAAGAGG
CTGGTGGAGAACGCGGTGCTCAAGGCTGTCCAGCAGTATCTGGAGGAAACACAGAATAAA
AACAAGCCGGGGGAGGGGAGCTCTGTGAAAACCGAAGCAGCTGATCAGAATGGCAATGAC
AATGAGAACAACAGGAAATGA
Protein Properties
Number of Residues 326
Molecular Weight 37058.9
Theoretical pI 5.76
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>A-kinase anchor protein 7 isoform gamma
MSEEFEANTMDSLVDMPFATVDIQDDCGITDEPQINLKRSQENEWVKSDQVKKRKKKRKD
YQPNYFLSIPITNKEIIKGIKILQNAIIQQDERLAKAMVSDGSFHITLLVMQLLNEDEVN
IGIDALLELKPFIEELLQGKHLTLPFQGIGTFGNQVGFVKLAEGDHVNSLLEIAETANRT
FQEKGILVGESRSFKPHLTFMKLSKSPWLRKNGVKKIDPDLYEKFISHRFGEEILYRIDL
CSMLKKKQSNGYYHCESSIVIGEKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNK
NKPGEGSSVKTEAADQNGNDNENNRK
GenBank ID Protein 6759917
UniProtKB/Swiss-Prot ID Q9P0M2
UniProtKB/Swiss-Prot Entry Name AKA7G_HUMAN
PDB IDs Not Available
GenBank Gene ID AF152929
GeneCard ID AKAP7
GenAtlas ID AKAP7
HGNC ID HGNC:377
References
General References
  1. Mungall AJ, Palmer SA, Sims SK, Edwards CA, Ashurst JL, Wilming L, Jones MC, Horton R, Hunt SE, Scott CE, Gilbert JG, Clamp ME, Bethel G, Milne S, Ainscough R, Almeida JP, Ambrose KD, Andrews TD, Ashwell RI, Babbage AK, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beare DM, Beasley H, Beasley O, Bird CP, Blakey S, Bray-Allen S, Brook J, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Clark SY, Clark G, Clee CM, Clegg S, Cobley V, Collier RE, Collins JE, Colman LK, Corby NR, Coville GJ, Culley KM, Dhami P, Davies J, Dunn M, Earthrowl ME, Ellington AE, Evans KA, Faulkner L, Francis MD, Frankish A, Frankland J, French L, Garner P, Garnett J, Ghori MJ, Gilby LM, Gillson CJ, Glithero RJ, Grafham DV, Grant M, Gribble S, Griffiths C, Griffiths M, Hall R, Halls KS, Hammond S, Harley JL, Hart EA, Heath PD, Heathcott R, Holmes SJ, Howden PJ, Howe KL, Howell GR, Huckle E, Humphray SJ, Humphries MD, Hunt AR, Johnson CM, Joy AA, Kay M, Keenan SJ, Kimberley AM, King A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd CR, Lloyd DM, Loveland JE, Lovell J, Martin S, Mashreghi-Mohammadi M, Maslen GL, Matthews L, McCann OT, McLaren SJ, McLay K, McMurray A, Moore MJ, Mullikin JC, Niblett D, Nickerson T, Novik KL, Oliver K, Overton-Larty EK, Parker A, Patel R, Pearce AV, Peck AI, Phillimore B, Phillips S, Plumb RW, Porter KM, Ramsey Y, Ranby SA, Rice CM, Ross MT, Searle SM, Sehra HK, Sheridan E, Skuce CD, Smith S, Smith M, Spraggon L, Squares SL, Steward CA, Sycamore N, Tamlyn-Hall G, Tester J, Theaker AJ, Thomas DW, Thorpe A, Tracey A, Tromans A, Tubby B, Wall M, Wallis JM, West AP, White SS, Whitehead SL, Whittaker H, Wild A, Willey DJ, Wilmer TE, Wood JM, Wray PW, Wyatt JC, Young L, Younger RM, Bentley DR, Coulson A, Durbin R, Hubbard T, Sulston JE, Dunham I, Rogers J, Beck S: The DNA sequence and analysis of human chromosome 6. Nature. 2003 Oct 23;425(6960):805-11. [PubMed:14574404 ]
  2. Trotter KW, Fraser ID, Scott GK, Stutts MJ, Scott JD, Milgram SL: Alternative splicing regulates the subcellular localization of A-kinase anchoring protein 18 isoforms. J Cell Biol. 1999 Dec 27;147(7):1481-92. [PubMed:10613906 ]