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Identification
HMDB Protein ID HMDBP08171
Secondary Accession Numbers
  • 13882
Name 40S ribosomal protein S27
Synonyms
  1. MPS-1
  2. Metallopan-stimulin 1
Gene Name RPS27
Protein Type Unknown
Biological Properties
General Function Involved in structural constituent of ribosome
Specific Function Not Available
Pathways Not Available
Reactions Not Available
GO Classification
Component
cell part
macromolecular complex
intracellular
ribonucleoprotein complex
ribosome
Function
structural molecule activity
structural constituent of ribosome
Process
macromolecule biosynthetic process
cellular macromolecule biosynthetic process
translation
metabolic process
biosynthetic process
Cellular Location Not Available
Gene Properties
Chromosome Location Chromosome:1
Locus 1q21
SNPs RPS27
Gene Sequence
>255 bp
ATGCCTCTCGCAAAGGATCTCCTTCATCCCTCTCCAGAAGAGGAGAAGAGGAAACACAAG
AAGAAACGCCTGGTGCAGAGCCCCAATTCCTACTTCATGGATGTGAAATGCCCAGGATGC
TATAAAATCACCACGGTCTTTAGCCATGCACAAACGGTAGTTTTGTGTGTTGGCTGCTCC
ACTGTCCTCTGCCAGCCTACAGGAGGAAAAGCAAGGCTTACAGAAGGATGTTCCTTCAGG
AGGAAGCAGCACTAA
Protein Properties
Number of Residues 84
Molecular Weight 9461.1
Theoretical pI 9.99
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>40S ribosomal protein S27
MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCS
TVLCQPTGGKARLTEGCSFRRKQH
GenBank ID Protein 4506711
UniProtKB/Swiss-Prot ID P42677
UniProtKB/Swiss-Prot Entry Name RS27_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001030.4
GeneCard ID RPS27
GenAtlas ID RPS27
HGNC ID HGNC:10416
References
General References
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  2. Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M: Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science. 2009 Aug 14;325(5942):834-40. doi: 10.1126/science.1175371. Epub 2009 Jul 16. [PubMed:19608861 ]
  3. Dephoure N, Zhou C, Villen J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP: A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10762-7. doi: 10.1073/pnas.0805139105. Epub 2008 Jul 31. [PubMed:18669648 ]
  4. Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Korner R, Greff Z, Keri G, Stemmann O, Mann M: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. Mol Cell. 2008 Aug 8;31(3):438-48. doi: 10.1016/j.molcel.2008.07.007. [PubMed:18691976 ]
  5. Oppermann FS, Gnad F, Olsen JV, Hornberger R, Greff Z, Keri G, Mann M, Daub H: Large-scale proteomics analysis of the human kinome. Mol Cell Proteomics. 2009 Jul;8(7):1751-64. doi: 10.1074/mcp.M800588-MCP200. Epub 2009 Apr 15. [PubMed:19369195 ]
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  8. Heibeck TH, Ding SJ, Opresko LK, Zhao R, Schepmoes AA, Yang F, Tolmachev AV, Monroe ME, Camp DG 2nd, Smith RD, Wiley HS, Qian WJ: An extensive survey of tyrosine phosphorylation revealing new sites in human mammary epithelial cells. J Proteome Res. 2009 Aug;8(8):3852-61. doi: 10.1021/pr900044c. [PubMed:19534553 ]
  9. Vladimirov SN, Ivanov AV, Karpova GG, Musolyamov AK, Egorov TA, Thiede B, Wittmann-Liebold B, Otto A: Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry. Eur J Biochem. 1996 Jul 1;239(1):144-9. [PubMed:8706699 ]
  10. Yoshihama M, Uechi T, Asakawa S, Kawasaki K, Kato S, Higa S, Maeda N, Minoshima S, Tanaka T, Shimizu N, Kenmochi N: The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. Genome Res. 2002 Mar;12(3):379-90. [PubMed:11875025 ]
  11. Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC: A map of 75 human ribosomal protein genes. Genome Res. 1998 May;8(5):509-23. [PubMed:9582194 ]
  12. Fernandez-Pol JA, Klos DJ, Hamilton PD: A growth factor-inducible gene encodes a novel nuclear protein with zinc finger structure. J Biol Chem. 1993 Oct 5;268(28):21198-204. [PubMed:8407955 ]
  13. Tsui SK, Lee SM, Fung KP, Waye MM, Lee CY: Primary structures and sequence analysis of human ribosomal proteins L39 and S27. Biochem Mol Biol Int. 1996 Oct;40(3):611-6. [PubMed:8908372 ]