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HMDB Protein ID HMDBP08241
Secondary Accession Numbers
  • 13953
Name Probable low affinity copper uptake protein 2
  1. Copper transporter 2
  2. Solute carrier family 31 member 2
  3. hCTR2
Gene Name SLC31A2
Protein Type Transporter
Biological Properties
General Function Involved in copper ion transmembrane transporter activity
Specific Function Involved in low-affinity copper uptake (Potential)
Pathways Not Available
Reactions Not Available
GO Classification
cell part
membrane part
intrinsic to membrane
integral to membrane
di-, tri-valent inorganic cation transmembrane transporter activity
copper ion transmembrane transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
transporter activity
copper ion transport
establishment of localization
ion transport
cation transport
metal ion transport
transition metal ion transport
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein (Probable)
Gene Properties
Chromosome Location Chromosome:9
Locus 9q31-q32
Gene Sequence
>432 bp
Protein Properties
Number of Residues 143
Molecular Weight 15681.3
Theoretical pI 6.79
Pfam Domain Function
  • None
Transmembrane Regions
  • 23-43
  • 94-114
  • 120-140
Protein Sequence
>Probable low affinity copper uptake protein 2
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID O15432
UniProtKB/Swiss-Prot Entry Name COPT2_HUMAN
PDB IDs Not Available
GenBank Gene ID U83461
GeneCard ID SLC31A2
GenAtlas ID SLC31A2
General References
  1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]
  2. Zhou B, Gitschier J: hCTR1: a human gene for copper uptake identified by complementation in yeast. Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7481-6. [PubMed:9207117 ]