Hmdb loader
Identification
HMDB Protein ID HMDBP08253
Secondary Accession Numbers
  • 13965
Name Putative DBH-like monooxygenase protein 2
Synonyms Not Available
Gene Name MOXD2
Protein Type Unknown
Biological Properties
General Function Involved in monooxygenase activity
Specific Function Not Available
Pathways Not Available
Reactions Not Available
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
catalytic activity
transition metal ion binding
monooxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
copper ion binding
dopamine beta-monooxygenase activity
Process
metabolic process
cellular process
cellular metabolic process
oxidation reduction
cellular amino acid derivative metabolic process
cellular biogenic amine metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process
catecholamine metabolic process
histidine family amino acid metabolic process
histidine metabolic process
histidine catabolic process
Cellular Location Not Available
Gene Properties
Chromosome Location Chromosome:7
Locus 7q34
SNPs MOXD2
Gene Sequence Not Available
Protein Properties
Number of Residues 499
Molecular Weight 56319.0
Theoretical pI 4.4
Pfam Domain Function
Signals
  • 1-16
Transmembrane Regions
  • None
Protein Sequence
>Putative DBH-like monooxygenase protein 2
MAHDLLFRLFPLLALGVPLQSNRLGPTSRLRYSRFLDPSNVIFLRWDFDLEAEIISFELQ
VRTAGWVGFGVTNRYTNVGSDLVVGGVLPNGNVYFSDQHLVEEDTLKEDGSQDAELLGLT
EDAVYTTMHFSRPFRSCDPHDLDITSNTVRVLAAYGLDDTLKLYRERTFVKSIFLLQVVH
PDDLDVPEDTIIHDLEITNFLIPEDDTTYACTFLPLPIVSEKHHIYKFEPKLVYHNETTV
HHILVYACGNASVLPTGISDCYGADPAFSLCSQVIVGSAVGGTSYQFPDDVGVSIGTPLD
PQWILEIHYSNFNNLPGVYDSSGIRVYYTSQLCKYDTDVLQLGFFTFPIHFIPPGAESFM
SYGLCRTEKFEEMNGAPMPDIQVYGYLLHTHLAGRALQAVQYRNGTQLRKICKDDSYDFN
LQETRDLPSRVEIKPGDELLVECHYQTLDRDSMTFGGPSTINEMCLIFLFYYPQNNISSC
MGYPDIIYVAHELGEEASE
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID A6NHM9
UniProtKB/Swiss-Prot Entry Name MOXD2_HUMAN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID MOXD2
GenAtlas ID MOXD2
HGNC ID HGNC:33605
References
General References
  1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]
  2. Hillier LW, Fulton RS, Fulton LA, Graves TA, Pepin KH, Wagner-McPherson C, Layman D, Maas J, Jaeger S, Walker R, Wylie K, Sekhon M, Becker MC, O'Laughlin MD, Schaller ME, Fewell GA, Delehaunty KD, Miner TL, Nash WE, Cordes M, Du H, Sun H, Edwards J, Bradshaw-Cordum H, Ali J, Andrews S, Isak A, Vanbrunt A, Nguyen C, Du F, Lamar B, Courtney L, Kalicki J, Ozersky P, Bielicki L, Scott K, Holmes A, Harkins R, Harris A, Strong CM, Hou S, Tomlinson C, Dauphin-Kohlberg S, Kozlowicz-Reilly A, Leonard S, Rohlfing T, Rock SM, Tin-Wollam AM, Abbott A, Minx P, Maupin R, Strowmatt C, Latreille P, Miller N, Johnson D, Murray J, Woessner JP, Wendl MC, Yang SP, Schultz BR, Wallis JW, Spieth J, Bieri TA, Nelson JO, Berkowicz N, Wohldmann PE, Cook LL, Hickenbotham MT, Eldred J, Williams D, Bedell JA, Mardis ER, Clifton SW, Chissoe SL, Marra MA, Raymond C, Haugen E, Gillett W, Zhou Y, James R, Phelps K, Iadanoto S, Bubb K, Simms E, Levy R, Clendenning J, Kaul R, Kent WJ, Furey TS, Baertsch RA, Brent MR, Keibler E, Flicek P, Bork P, Suyama M, Bailey JA, Portnoy ME, Torrents D, Chinwalla AT, Gish WR, Eddy SR, McPherson JD, Olson MV, Eichler EE, Green ED, Waterston RH, Wilson RK: The DNA sequence of human chromosome 7. Nature. 2003 Jul 10;424(6945):157-64. [PubMed:12853948 ]
  3. Hahn Y, Jeong S, Lee B: Inactivation of MOXD2 and S100A15A by exon deletion during human evolution. Mol Biol Evol. 2007 Oct;24(10):2203-12. Epub 2007 Jul 21. [PubMed:17642472 ]