Showing Protein Coatomer subunit delta (HMDBP08332)
Identification | |||||||||||||||
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HMDB Protein ID | HMDBP08332 | ||||||||||||||
Secondary Accession Numbers |
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Name | Coatomer subunit delta | ||||||||||||||
Synonyms |
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Gene Name | ARCN1 | ||||||||||||||
Protein Type | Unknown | ||||||||||||||
Biological Properties | |||||||||||||||
General Function | Involved in protein binding | ||||||||||||||
Specific Function | The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors | ||||||||||||||
Pathways | Not Available | ||||||||||||||
Reactions | Not Available | ||||||||||||||
GO Classification |
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Cellular Location |
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Gene Properties | |||||||||||||||
Chromosome Location | Chromosome:1 | ||||||||||||||
Locus | 11q23.3 | ||||||||||||||
SNPs | ARCN1 | ||||||||||||||
Gene Sequence |
>1536 bp ATGGTGCTGTTGGCAGCAGCGGTCTGCACAAAAGCAGGAAAGGCTATTGTTTCTCGACAG TTTGTGGAAATGACCCGAACTCGGATTGAGGGCTTATTAGCAGCTTTTCCAAAGCTCATG AACACTGGAAAACAACATACGTTTGTTGAAACAGAGAGTGTAAGATATGTCTACCAGCCT ATGGAGAAACTGTATATGGTACTGATCACTACCAAAAACAGCAACATTTTAGAAGATTTG GAGACCCTAAGGCTCTTCTCAAGAGTGATCCCTGAATATTGCCGAGCCTTAGAAGAGAAT GAAATATCTGAGCACTGTTTTGATTTGATTTTTGCTTTTGATGAAATTGTCGCACTGGGA TACCGGGAGAATGTTAACTTGGCACAGATCAGAACCTTCACAGAAATGGATTCTCATGAG GAGAAGGTGTTCAGAGCCGTCAGAGAGACTCAAGAACGTGAAGCTAAGGCTGAGATGCGT CGTAAAGCAAAGGAATTACAACAGGCCCGAAGAGATGCAGAGAGACAGGGCAAAAAAGCA CCAGGATTTGGCGGATTTGGCAGCTCTGCAGTATCTGGAGGCAGCACAGCTGCCATGATC ACAGAGACCATCATTGAAACTGATAAACCAAAAGTGGCACCTGCACCAGCCAGGCCTTCA GGCCCCAGCAAGGCTTTAAAACTTGGAGCCAAAGGAAAGGAAGTAGATAACTTTGTGGAC AAATTAAAATCTGAAGGTGAAACCATCATGTCCTCTAGTATGGGCAAGCGTACTTCTGAA GCAACCAAAATGCATGCTCCACCCATTAATATGGAAAGTGTACATATGAAGATTGAAGAA AAGATAACATTAACCTGTGGACGAGACGGAGGATTACAGAATATGGAGTTGCATGGCATG ATCATGCTTAGGATCTCAGATGACAAGTATGGCCGAATTCGTCTTCATGTGGAAAATGAA GATAAGAAAGGGGTGCAGCTACAGACCCATCCAAATGTGGATAAAAAACTTTTCACTGCA GAGTCTCTAATTGGCCTGAAGAATCCAGAGAAGTCATTTCCAGTCAACAGTGACGTAGGG GTGCTAAAGTGGAGACTACAAACCACAGAGGAATCTTTTATTCCACTGACAATTAATTGC TGGCCCTCGGAGAGTGGAAATGGCTGTGATGTCAACATAGAATATGAGCTACAAGAAGAT AATTTAGAACTGAATGATGTGGTTATCACCATCCCACTCCCGTCTGGTGTCGGCGCGCCT GTTATCGGTGAGATCGATGGGGAGTATCGACATGACAGTCGACGAAATACCCTGGAGTGG TGCCTGCCTGTGATTGATGCCAAAAATAAGAGTGGCAGCCTGGAGTTTAGCATTGCTGGG CAGCCCAATGACTTCTTCCCTGTTCAAGTTTCCTTTGTCTCCAAGAAAAATTACTGTAAC ATACAGGTTACCAAAGTGACCCAGGTAGATGGAAACAGCCCCGTCAGGTTTTCCACAGAG ACCACTTTCCTAGTGGATAAGTATGAAATTCTGTAA |
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Protein Properties | |||||||||||||||
Number of Residues | 511 | ||||||||||||||
Molecular Weight | 57209.9 | ||||||||||||||
Theoretical pI | 6.11 | ||||||||||||||
Pfam Domain Function | |||||||||||||||
Signals |
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Transmembrane Regions |
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Protein Sequence |
>Coatomer subunit delta MVLLAAAVCTKAGKAIVSRQFVEMTRTRIEGLLAAFPKLMNTGKQHTFVETESVRYVYQP MEKLYMVLITTKNSNILEDLETLRLFSRVIPEYCRALEENEISEHCFDLIFAFDEIVALG YRENVNLAQIRTFTEMDSHEEKVFRAVRETQEREAKAEMRRKAKELQQARRDAERQGKKA PGFGGFGSSAVSGGSTAAMITETIIETDKPKVAPAPARPSGPSKALKLGAKGKEVDNFVD KLKSEGETIMSSSMGKRTSEATKMHAPPINMESVHMKIEEKITLTCGRDGGLQNMELHGM IMLRISDDKYGRIRLHVENEDKKGVQLQTHPNVDKKLFTAESLIGLKNPEKSFPVNSDVG VLKWRLQTTEESFIPLTINCWPSESGNGCDVNIEYELQEDNLELNDVVITIPLPSGVGAP VIGEIDGEYRHDSRRNTLEWCLPVIDAKNKSGSLEFSIAGQPNDFFPVQVSFVSKKNYCN IQVTKVTQVDGNSPVRFSTETTFLVDKYEIL |
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External Links | |||||||||||||||
GenBank ID Protein | 62739405 | ||||||||||||||
UniProtKB/Swiss-Prot ID | P48444 | ||||||||||||||
UniProtKB/Swiss-Prot Entry Name | COPD_HUMAN | ||||||||||||||
PDB IDs | Not Available | ||||||||||||||
GenBank Gene ID | BC093636 | ||||||||||||||
GeneCard ID | ARCN1 | ||||||||||||||
GenAtlas ID | ARCN1 | ||||||||||||||
HGNC ID | HGNC:649 | ||||||||||||||
References | |||||||||||||||
General References |
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