Hmdb loader
Identification
HMDB Protein ID HMDBP08389
Secondary Accession Numbers
  • 14101
Name F-box only protein 8
Synonyms
  1. F-box/SEC7 protein FBS
Gene Name FBXO8
Protein Type Unknown
Biological Properties
General Function Involved in ARF guanyl-nucleotide exchange factor activity
Specific Function May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential)
Pathways Not Available
Reactions Not Available
GO Classification
Component
cell part
intracellular
Function
small gtpase regulator activity
enzyme regulator activity
arf guanyl-nucleotide exchange factor activity
nucleoside-triphosphatase regulator activity
gtpase regulator activity
Process
regulation of ras protein signal transduction
biological regulation
regulation of biological process
regulation of arf protein signal transduction
regulation of cellular process
regulation of cell communication
regulation of signal transduction
regulation of small gtpase mediated signal transduction
Cellular Location Not Available
Gene Properties
Chromosome Location Chromosome:4
Locus 4q34.1
SNPs FBXO8
Gene Sequence
>960 bp
ATGGGTCAAGGGTTGTGGAGAGTGGTCAGAAACCAGCAGCTGCAACAAGAAGGCTACAGT
GAGCAAGGCTACCTCACCAGAGAGCAGAGCAGGAGAATGGCTGCGAGCAACATTTCTAAC
ACCAATCATCGTAAACAAGTCCAAGGAGGCATTGACATATATCATCTTTTGAAGGCAAGG
AAATCGAAAGAACAGGAAGGATTCATTAATTTGGAAATGTTGCCTCCTGAGCTAAGCTTT
ACCATCTTGTCCTACCTGAATGCAACTGACCTTTGCTTGGCTTCATGTGTTTGGCAGGAC
CTTGCGAATGATGAACTTCTCTGGCAAGGGTTGTGCAAATCCACTTGGGGTCACTGTTCC
ATATACAATAAGAACCCACCTTTAGGATTTTCTTTTAGAAAATTGTATATGCAGCTGGAT
GAAGGCAGCCTCACCTTTAATGCCAACCCAGATGAGGGAGTGAACTACTTTATGTCCAAG
GGTATCCTGGATGATTCGCCAAAGGAAATAGCAAAGTTTATCTTCTGTACAAGAACACTA
AATTGGAAAAAACTGAGAATCTATCTTGATGAAAGGAGAGATGTCTTGGATGACCTTGTA
ACATTGCATAATTTTAGAAATCAGTTCTTGCCAAATGCACTGAGAGAATTTTTTCGTCAT
ATCCATGCCCCTGAAGAGCGTGGAGAGTATCTTGAAACTCTTATAACAAAGTTCTCACAT
AGATTCTGTGCTTGCAACCCTGATTTAATGCGAGAACTTGGCCTTAGTCCTGATGCTGTC
TATGTACTGTGCTACTCTTTGATTCTACTTTCCATTGACCTCACTAGCCCTCATGTGAAG
AATAAAATGTCAAAAAGGGAATTTATTCGAAATACCCGTCGCGCTGCTCAAAATATTAGT
GAAGATTTTGTAGGGCATCTTTATGACAATATCTACCTTATTGGCCATGTGGCTGCATAA
Protein Properties
Number of Residues 319
Molecular Weight 37068.0
Theoretical pI 7.78
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>F-box only protein 8
MGQGLWRVVRNQQLQQEGYSEQGYLTREQSRRMAASNISNTNHRKQVQGGIDIYHLLKAR
KSKEQEGFINLEMLPPELSFTILSYLNATDLCLASCVWQDLANDELLWQGLCKSTWGHCS
IYNKNPPLGFSFRKLYMQLDEGSLTFNANPDEGVNYFMSKGILDDSPKEIAKFIFCTRTL
NWKKLRIYLDERRDVLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSH
RFCACNPDLMRELGLSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTRRAAQNIS
EDFVGHLYDNIYLIGHVAA
GenBank ID Protein 48928044
UniProtKB/Swiss-Prot ID Q9NRD0
UniProtKB/Swiss-Prot Entry Name FBX8_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_012180.2
GeneCard ID FBXO8
GenAtlas ID FBXO8
HGNC ID HGNC:13587
References
General References
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