Hmdb loader
Identification
HMDB Protein ID HMDBP08423
Secondary Accession Numbers
  • 14135
Name GTPase IMAP family member 1
Synonyms
  1. Immunity-associated protein 1
  2. hIMAP1
Gene Name GIMAP1
Protein Type Unknown
Biological Properties
General Function Involved in GTP binding
Specific Function Not Available
Pathways Not Available
Reactions Not Available
GO Classification
Function
purine nucleotide binding
binding
nucleotide binding
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
Cellular Location
  1. Endoplasmic reticulum membrane
  2. Single-pass type IV membrane protein
Gene Properties
Chromosome Location Chromosome:7
Locus 7q36.1
SNPs GIMAP1
Gene Sequence
>921 bp
ATGGGAGGAAGGAAGATGGCGACAGATGAAGAAAATGTCTATGGTTTAGAAGAGAACGCT
CAGTCCCGGCAGGAGTCCACGCGGAGGCTCATCCTTGTTGGGAGAACAGGGGCCGGGAAG
AGCGCCACTGGGAACAGCATCCTGGGCCAGAGACGGTTCTTCTCCAGGCTGGGGGCCACG
TCTGTGACCAGGGCCTGCACCACGGGCAGCCGCAGGTGGGACAAGTGCCACGTGGAAGTC
GTGGACACTCCGGACATTTTCAGCTCCCAAGTGTCCAAGACAGATCCTGGCTGTGAGGAG
AGAGGTCACTGCTACCTGCTCTCGGCCCCCGGACCCCACGCGCTGCTCCTGGTGACCCAG
TTGGGTCGGTTCACCGCCCAGGACCAGCAGGCGGTGAGGCAGGTGAGGGACATGTTCGGG
GAGGACGTCCTAAAATGGATGGTCATCGTCTTCACCAGGAAGGAGGACCTGGCCGGGGGC
TCCCTGCACGATTACGTGAGCAACACAGAGAACCGGGCCTTGCGCGAGCTGGTGGCCGAG
TGCGGGGGCCGGGTCTGTGCCTTTGATAACCGGGCCACCGGCCGGGAGCAGGAAGCCCAG
GTGGAGCAGCTGCTGGGGATGGTCGAGGGCTTGGTGCTGGAGCACAAGGGCGCCCATTAC
TCCAACGAGGTGTATGAGCTGGCGCAGGTGCTGCGCTGGGCAGGCCCTGAGGAGCGGCTC
CGGCGGGTGGCGGAGCGCGTGGCAGCCAGGGTGCAGAGGAGGCCATGGGGCGCCTGGCTG
TCGGCCCGGCTGTGGAAGTGGCTGAAGTCCCCCAGGAGCTGGAGGCTGGGCCTGGCCCTG
CTGCTGGGGGGCGCGCTCCTGTTCTGGGTGCTGCTCCACAGGCGGTGGTCGGAGGCCGTT
GCGGAGGTCGGGCCTGACTGA
Protein Properties
Number of Residues 306
Molecular Weight 34368.9
Theoretical pI 9.06
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • 273-292
Protein Sequence
>GTPase IMAP family member 1
MGGRKMATDEENVYGLEENAQSRQESTRRLILVGRTGAGKSATGNSILGQRRFFSRLGAT
SVTRACTTGSRRWDKCHVEVVDTPDIFSSQVSKTDPGCEERGHCYLLSAPGPHALLLVTQ
LGRFTAQDQQAVRQVRDMFGEDVLKWMVIVFTRKEDLAGGSLHDYVSNTENRALRELVAE
CGGRVCAFDNRATGREQEAQVEQLLGMVEGLVLEHKGAHYSNEVYELAQVLRWAGPEERL
RRVAERVAARVQRRPWGAWLSARLWKWLKSPRSWRLGLALLLGGALLFWVLLHRRWSEAV
AEVGPD
GenBank ID Protein 18477214
UniProtKB/Swiss-Prot ID Q8WWP7
UniProtKB/Swiss-Prot Entry Name GIMA1_HUMAN
PDB IDs Not Available
GenBank Gene ID AJ306287
GeneCard ID GIMAP1
GenAtlas ID GIMAP1
HGNC ID HGNC:23237
References
General References
  1. Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S: Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 2004 Jan;36(1):40-5. Epub 2003 Dec 21. [PubMed:14702039 ]
  2. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]
  3. Sjoblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE: The consensus coding sequences of human breast and colorectal cancers. Science. 2006 Oct 13;314(5797):268-74. Epub 2006 Sep 7. [PubMed:16959974 ]
  4. Stamm O, Krucken J, Schmitt-Wrede HP, Benten WP, Wunderlich F: Human ortholog to mouse gene imap38 encoding an ER-localizable G-protein belongs to a gene family clustered on chromosome 7q32-36. Gene. 2002 Jan 9;282(1-2):159-67. [PubMed:11814688 ]